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2CSW
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Solution structure of the FHA domain of human ubiquitin ligase protein RNF8
分子名称: Ubiquitin ligase protein RNF8
著者Hayashi, F, Nagashima, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-23
公開日2005-11-23
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the FHA domain of human ubiquitin ligase protein RNF8
To be Published
6AR0
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BU of 6ar0 by Molmil
Structure of human SLMAP FHA domain
分子名称: Sarcolemmal membrane-associated protein
著者Ni, L, Luo, X.
登録日2017-08-21
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
Elife, 6, 2017
6AR2
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BU of 6ar2 by Molmil
Structure of human SLMAP FHA domain in complex with pMST2
分子名称: ASP-GLY-TPO-MET-LYS-ARG, Sarcolemmal membrane-associated protein
著者Osinski, A, Ni, L, Luo, X.
登録日2017-08-21
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
Elife, 6, 2017
1FHR
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BU of 1fhr by Molmil
SOLUTION STRUCTURE OF THE FHA2 DOMAIN OF RAD53 COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE
分子名称: DNA REPAIR PROTEIN RAD9, PROTEIN KINASE SPK1
著者Byeon, I.-J.L, Liao, H, Yongkiettrakul, S, Tsai, M.-D.
登録日2000-08-02
公開日2000-10-18
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides.
J.Mol.Biol., 302, 2000
1FHQ
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REFINED SOLUTION STRUCTURE OF THE FHA2 DOMAIN OF RAD53
分子名称: PROTEIN KINASE SPK1
著者Byeon, I.-J.L, Liao, H, Tsai, M.-D.
登録日2000-08-02
公開日2000-10-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides.
J.Mol.Biol., 302, 2000
6C4U
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BU of 6c4u by Molmil
Engineered FHA with Myc-pTBD peptide
分子名称: Forkhead-associated 1, GLYCEROL, Myc-pTBD peptide
著者Kall, S.L, Lavie, A.
登録日2018-01-12
公開日2018-05-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Generating a recombinant phosphothreonine-binding domain for a phosphopeptide of the human transcription factor, c-Myc.
N Biotechnol, 45, 2018
1G6G
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BU of 1g6g by Molmil
X-RAY STRUCTURE OF THE N-TERMINAL FHA DOMAIN FROM S. CEREVISIAE RAD53P IN COMPLEX WITH A PHOSPHOTHREONINE PEPTIDE AT 1.6 A RESOLUTION
分子名称: PROTEIN KINASE RAD53, SER-LEU-GLU-VAL-TPO-GLU-ALA-ASPALA-THR-PHE-ALA-LYS
著者Durocher, D, Taylor, I.A.
登録日2000-11-06
公開日2000-12-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms.
Mol.Cell, 6, 2000
6CAH
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BU of 6cah by Molmil
NMR-based structure of the FHA-2 domain from Mycobacterium tuberculosis ABC transporter Rv1747
分子名称: ABC transporter ATP-binding/permease protein Rv1747
著者Heinkel, F, Okon, M, Gsponer, J, McIntosh, L.P.
登録日2018-01-30
公開日2018-06-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747.
Structure, 26, 2018
1G3G
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NMR STRUCTURE OF THE FHA1 DOMAIN OF YEAST RAD53
分子名称: PROTEIN KINASE SPK1
著者Yuan, C, Liao, H, Su, M, Yongkiettrakul, S, Byeon, I.-J.L, Tsai, M.-D.
登録日2000-10-24
公開日2001-01-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the FHA1 domain of yeast Rad53 and identification of binding sites for both FHA1 and its target protein Rad9
J.Mol.Biol., 304, 2000
1GXC
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BU of 1gxc by Molmil
FHA domain from human Chk2 kinase in complex with a synthetic phosphopeptide
分子名称: SERINE/THREONINE-PROTEIN KINASE CHK2, SYNTHETIC PHOSPHOPEPTIDE
著者Li, J, Williams, B.L, Haire, L.F, Goldberg, M, Wilker, E, Durocher, D, Yaffe, M.B, Jackson, S.P, Smerdon, S.J.
登録日2002-04-02
公開日2002-06-13
最終更新日2016-12-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2
Mol.Cell, 9, 2002
6CCD
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BU of 6ccd by Molmil
The crystal structure of Mycobacterium tuberculosis Rv1747 FHA-1
分子名称: ABC transporter ATP-binding/permease protein Rv1747, SULFATE ION
著者Gay, L.M, Gee, C.L, Alber, T.
登録日2018-02-06
公開日2018-06-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747.
Structure, 26, 2018
3UN0
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BU of 3un0 by Molmil
Crystal Structure of MDC1 FHA Domain
分子名称: Mediator of DNA damage checkpoint protein 1, SULFATE ION
著者Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J.
登録日2011-11-15
公開日2011-12-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.
Nucleic Acids Res., 40, 2012
3UMZ
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BU of 3umz by Molmil
Crystal Structure of the human MDC1 FHA Domain
分子名称: Mediator of DNA damage checkpoint protein 1
著者Luo, S, Ye, K.
登録日2011-11-15
公開日2012-01-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
Nucleic Acids Res., 40, 2012
3UOT
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Crystal Structure of MDC1 FHA Domain in Complex with a Phosphorylated Peptide from the MDC1 N-terminus
分子名称: Mediator of DNA damage checkpoint protein 1
著者Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J.
登録日2011-11-17
公開日2011-12-28
最終更新日2012-07-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.
Nucleic Acids Res., 40, 2012
3UNM
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BU of 3unm by Molmil
Crystal Structure of The Human MDC1 FHA Domain
分子名称: Mediator of DNA damage checkpoint protein 1
著者Luo, S, Ye, K.
登録日2011-11-16
公開日2012-01-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
Nucleic Acids Res., 40, 2012
3UNN
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BU of 3unn by Molmil
Monomeric structure of the human MDC1 FHA domain in complex with an MDC1 phospho-T4 peptide
分子名称: Mediator of DNA damage checkpoint protein 1, phospho-T4 peptide from Mediator of DNA damage checkpoint protein 1
著者Luo, S, Ye, K.
登録日2011-11-16
公開日2012-01-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
Nucleic Acids Res., 40, 2012
3VA4
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BU of 3va4 by Molmil
Crystal structure of the mammalian MDC1 FHA domain complexed with CHK2 pThr68 peptide
分子名称: Mediator of DNA damage checkpoint protein 1, Serine/threonine-protein kinase Chk2
著者Wu, H.H, Wu, P.Y, Huang, K.F, Kao, Y.Y, Tsai, M.D.
登録日2011-12-28
公開日2012-02-01
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68.
Biochemistry, 2012
3I0N
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Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain
分子名称: DNA repair and telomere maintenance protein nbs1, GLYCEROL
著者Clapperton, J.A, Lloyd, J, Chapman, J.R, Jackson, S.P, Smerdon, S.J.
登録日2009-06-25
公開日2009-10-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage
Cell(Cambridge,Mass.), 139, 2009
3HX1
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BU of 3hx1 by Molmil
Crystal structure of the Slr1951 protein from Synechocystis sp. Northeast Structural Genomics Consortium Target SgR167A
分子名称: Slr1951 protein
著者Vorobiev, S, Chen, Y, Seetharaman, J, Janjua, J, Xiao, R, Ciccosanti, C, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2009-06-19
公開日2009-06-30
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the Slr1951 protein from Synechocystis sp.
To be Published
3HUF
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Structure of the S. pombe Nbs1-Ctp1 complex
分子名称: DNA repair and telomere maintenance protein nbs1, Double-strand break repair protein ctp1, THIOCYANATE ION
著者Williams, R.S, Guenther, G, Tainer, J.A.
登録日2009-06-13
公開日2009-10-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.
Cell(Cambridge,Mass.), 139, 2009
3I0M
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BU of 3i0m by Molmil
Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain
分子名称: DNA repair and telomere maintenance protein nbs1, GLYCEROL
著者Clapperton, J.A, Lloyd, J, Chapman, J.R, Jackson, S.P, Smerdon, S.J.
登録日2009-06-25
公開日2009-10-13
最終更新日2012-05-02
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage
Cell(Cambridge,Mass.), 139, 2009
3HUE
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BU of 3hue by Molmil
Structure of the S. pombe Nbs1 FHA-BRCT1-BRCT2 domains
分子名称: DNA repair and telomere maintenance protein nbs1
著者Williams, R.S, Guenther, G, Tainer, J.A.
登録日2009-06-13
公開日2009-10-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.
Cell(Cambridge,Mass.), 139, 2009
2JQJ
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BU of 2jqj by Molmil
NMR structure of yeast Dun1 FHA domain
分子名称: DNA damage response protein kinase DUN1
著者Yuan, C, Lee, H, Chang, C, Heierhorst, J, Tsai, M.
登録日2007-06-02
公開日2008-06-24
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade.
Mol.Cell, 30, 2008
2JQL
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NMR structure of the yeast Dun1 FHA domain in complex with a doubly phosphorylated (pT) peptide derived from Rad53 SCD1
分子名称: DNA damage response protein kinase DUN1, Serine/threonine-protein kinase RAD53
著者Yuan, C, Lee, H, Chang, C, Heierhorst, J, Tsai, M.
登録日2007-06-02
公開日2008-06-24
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade.
Mol.Cell, 30, 2008
5YYZ
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Crystal structure of the MEK1 FHA domain in complex with the HOP1 pThr318 peptide.
分子名称: Meiosis-specific protein HOP1, Meiosis-specific serine/threonine-protein kinase MEK1
著者Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y.
登録日2017-12-11
公開日2018-10-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献Structural insights into the recognition of phosphorylated Hop1 by Mek1
Acta Crystallogr D Struct Biol, 74, 2018

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