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2V7D
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14-3-3 protein zeta in complex with Thr758 phosphorylated integrin beta2 peptide
分子名称: 14-3-3 PROTEIN ZETA/DELTA, INTEGRIN BETA CHAIN, BETA 2 VARIANT
著者Takala, H, Ylanne, J.
登録日2007-07-30
公開日2008-06-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Beta2 Integrin Phosphorylation on Thr758 Acts as a Molecular Switch to Regulate 14-3-3 and Filamin Binding.
Blood, 112, 2008
2WH0
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BU of 2wh0 by Molmil
Recognition of an intrachain tandem 14-3-3 binding site within protein kinase C epsilon
分子名称: 14-3-3 PROTEIN ZETA/DELTA, CALCIUM ION, PROTEIN KINASE C EPSILON TYPE, ...
著者Kostelecky, B, Saurin, A.T, Purkiss, A, Parker, P.J, McDonald, N.Q.
登録日2009-04-28
公開日2009-08-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Recognition of an Intra-Chain Tandem 14-3-3 Binding Site within Pkc Epsilon.
Embo Rep., 10, 2009
3AXY
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BU of 3axy by Molmil
Structure of Florigen Activation Complex Consisting of Rice Florigen Hd3a, 14-3-3 Protein GF14 and Rice FD Homolog OsFD1
分子名称: 14-3-3-like protein GF14-C, Protein HEADING DATE 3A, Rice FD homolog OsFD1
著者Ohki, I, Furuita, K, Hayashi, K, Taoka, K, Tsuji, H, Nakagawa, A, Shimamoto, K, Kojima, C.
登録日2011-04-19
公開日2011-08-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献14-3-3 proteins act as intracellular receptors for rice Hd3a florigen
Nature, 476, 2011
3CU8
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BU of 3cu8 by Molmil
Impaired binding of 14-3-3 to Raf1 is linked to Noonan and LEOPARD syndrome
分子名称: 14-3-3 protein zeta/delta, MAGNESIUM ION, PROPANOIC ACID, ...
著者Schumacher, B, Weyand, M, Kuhlmann, J, Ottmann, C.
登録日2008-04-16
公開日2009-05-05
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol. Cell. Biol., 30, 2010
3E6Y
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BU of 3e6y by Molmil
Structure of 14-3-3 in complex with the differentiation-inducing agent Cotylenin A
分子名称: 14-3-3-like protein C, CHLORIDE ION, Cotylenin A, ...
著者Ottmann, C, Weyand, M, Wittinghofer, A, Oecking, C.
登録日2008-08-17
公開日2009-03-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A
J.Mol.Biol., 386, 2009
3EFZ
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BU of 3efz by Molmil
Crystal Structure of a 14-3-3 protein from cryptosporidium parvum (cgd1_2980)
分子名称: 1,2-ETHANEDIOL, 14-3-3 protein
著者Wernimont, A.K, Dong, A, Qiu, W, Lew, J, Wasney, G.A, Vedadi, M, Kozieradzki, I, Zhao, Y, Ren, H, Alam, Z, Lin, Y.H, Sundstrom, M, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Hui, R, Brokx, S, Structural Genomics Consortium (SGC)
登録日2008-09-10
公開日2008-09-23
最終更新日2012-02-22
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Characterization of 14-3-3 proteins from Cryptosporidium parvum.
Plos One, 6, 2011
3IQJ
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BU of 3iqj by Molmil
Crystal Structure of human 14-3-3 sigma in Complex with Raf1 peptide (10mer)
分子名称: 10-mer peptide from RAF proto-oncogene serine/threonine-protein kinase, 14-3-3 protein sigma, CHLORIDE ION, ...
著者Ottmann, C, Weyand, M.
登録日2009-08-20
公開日2010-09-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol.Cell.Biol., 30, 2010
3IQU
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Crystal Structure of human 14-3-3 sigma in Complex with Raf1 peptide (6mer)
分子名称: 14-3-3 protein sigma, 6-mer from RAF proto-oncogene serine/threonine-protein kinase, CHLORIDE ION, ...
著者Ottmann, C, Weyand, M.
登録日2009-08-21
公開日2010-09-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol.Cell.Biol., 30, 2010
3IQV
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BU of 3iqv by Molmil
Crystal Structure of human 14-3-3 sigma in Complex with Raf1 peptide (6mer) and stabilisator Fusicoccin
分子名称: 14-3-3 protein sigma, 6-mer peptide from RAF proto-oncogene serine/threonine-protein kinase, CHLORIDE ION, ...
著者Ottmann, C, Weyand, M.
登録日2009-08-21
公開日2010-09-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol.Cell.Biol., 30, 2010
3LW1
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BU of 3lw1 by Molmil
Binary complex of 14-3-3 sigma and p53 pT387-peptide
分子名称: 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ...
著者Schumacher, B, Mondry, J, Thiel, P, Weyand, M, Ottmann, C.
登録日2010-02-23
公開日2010-03-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Structure of the p53 C-terminus bound to 14-3-3: Implications for stabilization of the p53 tetramer
Febs Lett., 584, 2010
3M50
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BU of 3m50 by Molmil
Structure of the 14-3-3/PMA2 complex stabilized by Epibestatin
分子名称: 14-3-3-like protein C, N-[(2R,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]-L-leucine, N.plumbaginifolia H+-translocating ATPase mRNA
著者Ottmann, C, Rose, R, Waldmann, H.
登録日2010-03-12
公開日2010-05-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Identification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactions
Angew.Chem.Int.Ed.Engl., 49, 2010
3M51
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BU of 3m51 by Molmil
Structure of the 14-3-3/PMA2 complex stabilized by Pyrrolidone1
分子名称: 14-3-3-like protein C, 2-hydroxy-5-[(5S)-3-hydroxy-5-(4-nitrophenyl)-2-oxo-4-(phenylcarbonyl)-2,5-dihydro-1H-pyrrol-1-yl]benzoic acid, N.plumbaginifolia H+-translocating ATPase mRNA
著者Ottmann, C, Rose, R, Waldmann, H.
登録日2010-03-12
公開日2010-05-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Identification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactions
Angew.Chem.Int.Ed.Engl., 49, 2010
3MHR
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14-3-3 sigma in complex with YAP pS127-peptide
分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ...
著者Schumacher, B, Skwarczynska, M, Rose, R, Ottmann, C.
登録日2010-04-08
公開日2010-09-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structure of a 14-3-3[sigma]-YAP phosphopeptide complex at 1.15 A resolution
Acta Crystallogr.,Sect.F, 66, 2010
3NKX
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BU of 3nkx by Molmil
Impaired binding of 14-3-3 to Raf1 is linked to Noonan and LEOPARD syndrome
分子名称: 14-3-3 protein zeta/delta, PROPANOIC ACID, Peptide of RAF proto-oncogene serine/threonine-protein kinase
著者Schumacher, B, Weyand, M, Ottmann, C.
登録日2010-06-21
公開日2010-09-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling
Mol.Cell.Biol., 30, 2010
3O8I
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BU of 3o8i by Molmil
Structure of 14-3-3 isoform sigma in complex with a C-Raf1 peptide and a stabilizing small molecule fragment
分子名称: 14-3-3 binding site peptide of RAF proto-oncogene serine/threonine-protein kinase, 14-3-3 protein sigma, 6,6-dihydroxy-1-methoxyhexan-2-one
著者Ottmann, C, Rose, R, Kaiser, M, Kuhenne, P.
登録日2010-08-03
公開日2010-09-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling
Mol.Cell.Biol., 30, 2010
3P1N
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BU of 3p1n by Molmil
Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide
分子名称: 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CHLORIDE ION, ...
著者Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C.
登録日2010-09-30
公開日2011-10-12
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface
Chem. Biol., 20, 2013
3P1O
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BU of 3p1o by Molmil
Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilisator Fusicoccin A
分子名称: 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CALCIUM ION, ...
著者Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C.
登録日2010-09-30
公開日2011-10-12
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface
Chem. Biol., 20, 2013
3P1P
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BU of 3p1p by Molmil
Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide
分子名称: 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CHLORIDE ION, ...
著者Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C.
登録日2010-09-30
公開日2011-10-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface
Chem. Biol., 20, 2013
3P1Q
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BU of 3p1q by Molmil
Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 Peptide and stabilizer fusicoccin A
分子名称: 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CALCIUM ION, ...
著者Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C.
登録日2010-09-30
公開日2011-10-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface
Chem. Biol., 20, 2013
3P1R
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BU of 3p1r by Molmil
Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide
分子名称: 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CALCIUM ION, ...
著者Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C.
登録日2010-09-30
公開日2011-10-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface
Chem. Biol., 20, 2013
3P1S
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BU of 3p1s by Molmil
Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide and stabilizer fusicoccin A
分子名称: 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CHLORIDE ION, ...
著者Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C.
登録日2010-09-30
公開日2011-10-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface
Chem. Biol., 20, 2013
3RDH
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BU of 3rdh by Molmil
X-ray induced covalent inhibition of 14-3-3
分子名称: 14-3-3 protein zeta/delta, 4-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]benzoic acid, NICKEL (II) ION
著者Horton, J.R, Upadhyay, A.K, Fu, H, Cheng, X.
登録日2011-04-01
公開日2011-09-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor.
Proc.Natl.Acad.Sci.USA, 108, 2011
3SMK
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BU of 3smk by Molmil
Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer Cotylenin A
分子名称: 14-3-3 protein sigma, Cotylenin A, MAGNESIUM ION, ...
著者Anders, C, Schumacher, B, Ottmann, C.
登録日2011-06-28
公開日2012-07-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface.
Chem. Biol., 20, 2013
3SML
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BU of 3sml by Molmil
Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide and stabilizer Fusicoccin A aglycone
分子名称: 14-3-3 protein sigma, CHLORIDE ION, Fusicoccin A aglycone, ...
著者Anders, C, Schumacher, B, Ottmann, C.
登録日2011-06-28
公開日2012-07-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface.
Chem. Biol., 20, 2013
3SMM
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BU of 3smm by Molmil
Crystal structure of human 14-3-3 sigma C38N/N166H in complex with task-3 peptide and stabilizer Fusicoccin J aglycone
分子名称: 14-3-3 protein sigma, CHLORIDE ION, Fusicoccin J aglycone, ...
著者Anders, C, Schumacher, B, Ottmann, C.
登録日2011-06-28
公開日2012-07-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface.
Chem. Biol., 20, 2013

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