PDB: 253 件ウェブページステータス検索Chemie searchBIRD

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3KAR	THE MOTOR DOMAIN OF KINESIN-LIKE PROTEIN KAR3, A SACCHAROMYCES CEREVISIAE KINESIN-RELATED PROTEIN 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION 著者 Gulick, A.M, Song, H, Endow, S, Rayment, I. 登録日 1997-11-26 公開日 1998-04-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 X-ray crystal structure of the yeast Kar3 motor domain complexed with Mg.ADP to 2.3 A resolution. Biochemistry, 37, 1998
3LRE	Crystal Structure Analysis of Human Kinesin-8 Motor Domain 分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF18A, MAGNESIUM ION 著者 Brejc, K, Moores, C.A, Hartman, J. 登録日 2010-02-11 公開日 2010-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Insight into the molecular mechanism of the multitasking kinesin-8 motor. Embo J., 29, 2010
7RIK	Magic-Angle-Spinning NMR Structure of Kinesin-1 Motor Domain Assembled with Microtubules 分子名称: Kinesin-1 heavy chain 著者 Zhang, C, Guo, C, Russell, R.W, Quinn, C.M, Li, M, Williams, J.C, Gronenborn, A.M, Polenova, T. 登録日 2021-07-20 公開日 2022-11-23 最終更新日 2024-05-15 実験手法 SOLID-STATE NMR 主引用文献 Magic-angle-spinning NMR structure of the kinesin-1 motor domain assembled with microtubules reveals the elusive neck linker orientation Nat Commun, 13, 2022
8HFH	CENP-E motor domain in complex with AMPPNP and Mg2+ 分子名称: Centromere-associated protein E, IMIDAZOLE, MAGNESIUM ION, ... 著者 Shibuya, A, Yokoyama, H. 登録日 2022-11-10 公開日 2023-03-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the motor domain of centromere-associated protein E in complex with a non-hydrolysable ATP analogue. Febs Lett., 597, 2023
3T0Q	Motor Domain Structure of the Kar3-like kinesin from Ashbya gossypii 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, AGR253Wp, ... 著者 Duan, D, Hnatchuk, D.J, Brenner, J, Davis, D, Allingham, J.S. 登録日 2011-07-20 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structure of the Kar3-like kinesin motor domain from the filamentous fungus Ashbya gossypii. Proteins, 80, 2012
5W3D	The structure of kinesin-14 wild-type Ncd-ADP dimer 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein claret segregational 著者 Park, H.W, Ma, Z, Chacko, J, Jiang, S.M, Robinson, R.C, Endow, S.A. 登録日 2017-06-07 公開日 2017-12-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein. Sci Rep, 7, 2017
7EO9	Crystal structure of KIF1A Motor-Neck domain with ADP-Mg-AlFx 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Kinesin-like protein KIF1A, ... 著者 Ogawa, T, Jiang, X, Hirokawa, N. 登録日 2021-04-21 公開日 2021-12-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 A neuropathy-associated kinesin KIF1A mutation hyper-stabilizes the motor-neck interaction during the ATPase cycle. Embo J., 41, 2022
7EOB	Crystal structure of KIF1A Motor-Neck domain E239K mutant with ADP-Mg-AlFx 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Kinesin-like protein KIF1A, ... 著者 Ogawa, T, Jiang, X, Hirokawa, N. 登録日 2021-04-21 公開日 2021-12-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 A neuropathy-associated kinesin KIF1A mutation hyper-stabilizes the motor-neck interaction during the ATPase cycle. Embo J., 41, 2022
5WDH	Motor domain of human kinesin family member C1 分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIFC1, MAGNESIUM ION, ... 著者 Zhu, H, Tempel, W, He, H, Shen, Y, Wang, J, Brothers, G, Landry, R, Arrowsmith, C.H, Edwards, A.M, Park, H, Structural Genomics Consortium (SGC) 登録日 2017-07-05 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.248 Å) 主引用文献 Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein. Sci Rep, 7, 2017
5WDE	Crystal structure of the KIFC3 motor domain in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIFC3, MAGNESIUM ION, ... 著者 Shen, Y, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Park, H, Structural Genomics Consortium (SGC) 登録日 2017-07-05 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein. Sci Rep, 7, 2017
3U06	Crystal structure of the kinesin-14 NcdG347D 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... 著者 Liu, H.-L, Pemble IV, C.W, Endow, S.A. 登録日 2011-09-28 公開日 2012-03-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Neck-motor interactions trigger rotation of the kinesin stalk. Sci Rep, 2, 2012
1F9U	CRYSTAL STRUCTURES OF MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE KINESIN MOTOR ATPASE 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION 著者 Yun, M, Zhang, X, Park, C.G, Park, H.W, Endow, S.A. 登録日 2000-07-11 公開日 2001-06-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A structural pathway for activation of the kinesin motor ATPase. EMBO J., 20, 2001
1F9W	CRYSTAL STRUCTURES OF MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE KINESIN MOTOR ATPASE 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION 著者 Yun, M, Zhang, X, Park, C.G, Park, H.W, Endow, S.A. 登録日 2000-07-11 公開日 2001-06-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A structural pathway for activation of the kinesin motor ATPase. EMBO J., 20, 2001
1F9T	CRYSTAL STRUCTURES OF KINESIN MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE MOTOR ATPASE 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION 著者 Yun, M, Zhang, X, Park, C.-G, Park, H.-W, Endow, S.A. 登録日 2000-07-11 公開日 2001-06-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A structural pathway for activation of the kinesin motor ATPase. EMBO J., 20, 2001
4FRZ	Arabidopsis KCBP motor domain dimerized via regulatory domain 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, IMIDAZOLE, ... 著者 Vinogradova, M. 登録日 2012-06-26 公開日 2013-07-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Plant Kinesin-Like Calmodulin Binding Protein Employs Its Regulatory Domain for Dimerization. Plos One, 8, 2013
4GKR	Structure of the C-terminal motor domain of Kar3 from Candida glabrata 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Duan, D, Allingham, J.S. 登録日 2012-08-13 公開日 2012-10-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Neck Rotation and Neck Mimic Docking in the Noncatalytic Kar3-associated Protein Vik1. J.Biol.Chem., 287, 2012
1GOJ	Structure of a fast kinesin: Implications for ATPase mechanism and interactions with microtubules 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN HEAVY CHAIN, MAGNESIUM ION 著者 Song, Y.-H, Marx, A, Muller, J, Woehlke, G, Schliwa, M, Krebs, A, Hoenger, A, Mandelkow, E. 登録日 2001-10-21 公開日 2001-11-30 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of a Fast Kinesin: Implications for ATPase Mechanism and Interactions with Microtubules Embo J., 20, 2001
5LT0	nucleotide-free kinesin-1 motor domain, P212121 crystal form 分子名称: ACETATE ION, Kinesin-like protein, STRONTIUM ION, ... 著者 Cao, L, Gigant, B. 登録日 2016-09-06 公開日 2017-03-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structural switch of nucleotide-free kinesin. Sci Rep, 7, 2017
5LT2	nucleotide-free kinesin-1 motor domain, P1 crystal form 分子名称: Kinesin-like protein, SULFATE ION 著者 Cao, L, Gigant, B. 登録日 2016-09-06 公開日 2017-03-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The structural switch of nucleotide-free kinesin. Sci Rep, 7, 2017
5LT4	nucleotide-free kinesin-1 motor domain T92V mutant, P1 crystal form 分子名称: Kinesin-1 heavy chain, SULFATE ION 著者 Cao, L, Gigant, B. 登録日 2016-09-06 公開日 2017-03-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.881 Å) 主引用文献 The structural switch of nucleotide-free kinesin. Sci Rep, 7, 2017
5LT1	nucleotide-free kinesin-1 motor domain T92V mutant, P21 crystal form 分子名称: ACETATE ION, Kinesin-like protein, STRONTIUM ION, ... 著者 Cao, L, Gigant, B. 登録日 2016-09-06 公開日 2017-03-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.949 Å) 主引用文献 The structural switch of nucleotide-free kinesin. Sci Rep, 7, 2017
2FME	Crystal structure of the mitotic kinesin eg5 (ksp) in complex with mg-adp and (r)-4-(3-hydroxyphenyl)-n,n,7,8-tetramethyl-3,4-dihydroisoquinoline-2(1h)-carboxamide 分子名称: (4R)-4-(3-HYDROXYPHENYL)-N,N,7,8-TETRAMETHYL-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... 著者 Sheriff, S. 登録日 2006-01-09 公開日 2006-04-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Inhibitors of human mitotic kinesin Eg5: Characterization of the 4-phenyl-tetrahydroisoquinoline lead series Bioorg.Med.Chem.Lett., 16, 2006
2FKY	crystal structure of KSP in complex with inhibitor 13 分子名称: (2S)-4-(2,5-DIFLUOROPHENYL)-N-METHYL-2-PHENYL-N-PIPERIDIN-4-YL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... 著者 Yan, Y. 登録日 2006-01-05 公開日 2006-02-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Kinesin spindle protein (KSP) inhibitors. Part 2: the design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP. Bioorg.Med.Chem.Lett., 16, 2006
2FL2	crystal structure of KSP in complex with inhibitor 19 分子名称: (1S)-1-CYCLOPROPYL-2-[(2S)-4-(2,5-DIFLUOROPHENYL)-2-PHENYL-2,5-DIHYDRO-1H-PYRROL-1-YL]-2-OXOETHANAMINE, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... 著者 Yan, Y. 登録日 2006-01-05 公開日 2006-02-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Kinesin spindle protein (KSP) inhibitors. Part 2: the design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP. Bioorg.Med.Chem.Lett., 16, 2006
2FL6	crystal structure of KSP in complex with inhibitor 6 分子名称: (2S)-4-(2,5-DIFLUOROPHENYL)-N,N-DIMETHYL-2-PHENYL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... 著者 Yan, Y. 登録日 2006-01-05 公開日 2006-02-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Kinesin spindle protein (KSP) inhibitors. Part 2: the design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP. Bioorg.Med.Chem.Lett., 16, 2006

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