PDB: 302 件ウェブページステータス検索Chemie searchBIRD

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8V6H	DNA initiation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... 著者 Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. 登録日 2023-12-01 公開日 2023-12-20 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (11.11 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
8V6I	DNA elongation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... 著者 Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. 登録日 2023-12-01 公開日 2023-12-20 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (14.06 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
8HOY	Cryo-EM structure of monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex without DNA at 2.76 angostram 分子名称: DNA polymerase, DNA polymerase processivity factor component A20, E4R 著者 Xu, Y, Wu, Y, Zhang, Y, Fan, R, Yang, Y, Li, D, Yang, B, Zhang, Z, Dong, C. 登録日 2022-12-11 公開日 2023-12-13 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Structure of DNA replication machinery from human monkeypox virus To Be Published
8KG6	Yeast replisome in state I 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ... 著者 Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. 登録日 2023-08-17 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
8KG8	Yeast replisome in state II 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ... 著者 Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. 登録日 2023-08-17 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (4.23 Å) 主引用文献 Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
8KG9	Yeast replisome in state III 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ... 著者 Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. 登録日 2023-08-17 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (4.52 Å) 主引用文献 Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
8WPE	Structure of monkeypox virus polymerase complex F8-A22-E4-H5 (tag-free A22) with exogenous DNA 分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, A22R DNA polymerase processivity factor, DNA polymerase, ... 著者 Wang, X, Li, N, Gao, N. 登録日 2023-10-10 公開日 2023-11-29 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
8WPF	Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with exogenous DNA bearing one abasic site 分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, A22R DNA polymerase processivity factor, DNA polymerase, ... 著者 Wang, X, Li, N, Gao, N. 登録日 2023-10-10 公開日 2023-11-29 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
8WPK	Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with exgenous DNA 分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA polymerase, DNA polymerase processivity factor, ... 著者 Wang, X, Li, N, Gao, N. 登録日 2023-10-10 公開日 2023-11-29 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
8WPP	Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with endogenous DNA 分子名称: A22R DNA polymerase processivity factor, DNA polymerase, E4R Uracil-DNA glycosylase, ... 著者 Wang, X, Li, N, Gao, N. 登録日 2023-10-10 公開日 2023-11-29 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
8HDZ	Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in an apo form 分子名称: A22 DNA replication processivity factor, E4 uracil-DNA glycosylase, F8 DNA polymerase 著者 Xu, Y, Wu, Y, Zhang, Y, Fan, R, Yang, Y, Li, D, Yang, B, Zhang, Z, Dong, C. 登録日 2022-11-07 公開日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 Cryo-EM structures of human monkeypox viral replication complexes with and without DNA duplex. Cell Res., 33, 2023
8B76	The crystal structure of M644G variant of DNA Pol Epsilon containing dTTP in the polymerase active site 分子名称: ACETATE ION, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ... 著者 Parkash, V, Johansson, E. 登録日 2022-09-28 公開日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res., 2023
8B67	The crystal structure of M644G variant of DNA Pol Epsilon containing CTP in the polymerase active site 分子名称: ACETATE ION, CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Parkash, V, Johansson, E. 登録日 2022-09-26 公開日 2023-10-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res., 2023
8B79	The crystal structure of M644G variant of DNA Pol Epsilon containing UTP in the polymerase active site 分子名称: ACETATE ION, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ... 著者 Parkash, V, Johansson, E. 登録日 2022-09-29 公開日 2023-10-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res., 2023
8B7E	The crystal structure of N828V variant of DNA Pol Epsilon containing UTP in the polymerase active site 分子名称: CALCIUM ION, DNA polymerase epsilon catalytic subunit A, GLYCEROL, ... 著者 Parkash, V, Johansson, E. 登録日 2022-09-29 公開日 2023-10-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res., 2023
8B6K	The crystal structure of M644G variant of DNA Pol Epsilon containing dCTP in the polymerase active site 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ... 著者 Parkash, V, Johansson, E. 登録日 2022-09-27 公開日 2023-10-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res., 2023
8B77	The crystal structure of N828V variant of DNA Pol Epsilon containing dATP in the polymerase active site 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ... 著者 Parkash, V, Johansson, E. 登録日 2022-09-29 公開日 2023-10-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res., 2023
8UCV	Complete DNA termination subcomplex 1 of Xenopus laevis DNA polymerase alpha-primase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ... 著者 Mullins, E.A, Chazin, W.C, Eichman, B.F. 登録日 2023-09-27 公開日 2023-10-11 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.81 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
8UCU	Partial DNA termination subcomplex of Xenopus laevis DNA polymerase alpha-primase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ... 著者 Mullins, E.A, Chazin, W.J, Eichman, B.F. 登録日 2023-09-27 公開日 2023-10-11 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
8UCW	Complete DNA termination subcomplex 2 of Xenopus laevis DNA polymerase alpha-primase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ... 著者 Mullins, E.A, Chazin, W.C, Eichman, B.F. 登録日 2023-09-27 公開日 2023-10-11 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.64 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
8B9B	S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand. 分子名称: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ... 著者 Jones, M.L, Yeeles, J.T.P. 登録日 2022-10-05 公開日 2023-08-09 最終更新日 2023-08-30 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
8B9A	S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand. 分子名称: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ... 著者 Jones, M.L, Yeeles, J.T.P. 登録日 2022-10-05 公開日 2023-08-09 最終更新日 2023-08-30 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
8B9C	S. cerevisiae pol alpha - replisome complex 分子名称: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ... 著者 Jones, M.L, Yeeles, J.T.P. 登録日 2022-10-05 公開日 2023-08-09 最終更新日 2023-08-30 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
8B9D	Human replisome bound by Pol Alpha 分子名称: Cell division control protein 45 homolog, Claspin, DNA Molecule, ... 著者 Jones, M.L, Yeeles, J.T.P. 登録日 2022-10-05 公開日 2023-08-09 最終更新日 2023-08-30 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
8FOJ	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the post RNA handoff state 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023

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