PDB: 116 件ウェブページステータス検索Chemie searchBIRD

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6EUQ	MdfA(Q131R/L339E) 分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, ACETATE ION, HEXANE, ... 著者 Tam, H.K, Zomot, E, Bibi, E, Pos, K.M. 登録日 2017-10-31 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A New Critical Conformational Determinant of Multidrug Efflux by an MFS Transporter. J. Mol. Biol., 430, 2018
4GBZ	The structure of the MFS (major facilitator superfamily) proton:xylose symporter XylE bound to D-glucose 分子名称: D-xylose-proton symporter, beta-D-glucopyranose, nonyl beta-D-glucopyranoside 著者 Sun, L.F, Zeng, X, Yan, C.Y, Yan, N. 登録日 2012-07-28 公開日 2012-10-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.894 Å) 主引用文献 Crystal structure of a bacterial homologue of glucose transporters GLUT1-4. Nature, 490, 2012
4GC0	The structure of the MFS (major facilitator superfamily) proton:xylose symporter XylE bound to 6-bromo-6-deoxy-D-glucose 分子名称: 6-bromo-6-deoxy-beta-D-glucopyranose, D-xylose-proton symporter, nonyl beta-D-glucopyranoside 著者 Yan, N, Sun, L.F, Zeng, X, Yan, C.Y. 登録日 2012-07-28 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of a bacterial homologue of glucose transporters GLUT1-4. Nature, 490, 2012
7D5Q	Structure of NorC transporter (K398A mutant) in an outward-open conformation in complex with a single-chain Indian camelid antibody 分子名称: Drug transporter, putative, ICab, ... 著者 Kumar, S, Athreya, A, Penmatsa, A. 登録日 2020-09-27 公開日 2021-06-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural basis of inhibition of a transporter from Staphylococcus aureus, NorC, through a single-domain camelid antibody. Commun Biol, 4, 2021
7D5P	Structure of NorC transporter in an outward-open conformation in complex with a single-chain Indian camelid antibody 分子名称: Drug transporter, putative, ICab, ... 著者 Kumar, S, Athreya, A, Penmatsa, A. 登録日 2020-09-27 公開日 2021-06-09 最終更新日 2021-07-14 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 Structural basis of inhibition of a transporter from Staphylococcus aureus, NorC, through a single-domain camelid antibody. Commun Biol, 4, 2021
4LDS	The inward-facing structure of the glucose transporter from Staphylococcus epidermidis 分子名称: Glucose transporter GlcP 著者 Choe, J, Aleshin, A, Iancu, C.V. 登録日 2013-06-25 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of a glucose/H+ symporter and its mechanism of action. Proc.Natl.Acad.Sci.USA, 110, 2013
6THA	Crystal structure of human sugar transporter GLUT1 (SLC2A1) in the inward conformation 分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, Solute carrier family 2, ... 著者 Pedersen, B.P, Paulsen, P.A, Custodio, T.F. 登録日 2019-11-19 公開日 2020-11-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural comparison of GLUT1 to GLUT3 reveal transport regulation mechanism in sugar porter family. Life Sci Alliance, 4, 2021
6OOQ	protein C 分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, Multidrug transporter MdfA 著者 Lu, M. 登録日 2019-04-23 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of an engineered multidrug transporter MdfA reveals the molecular basis for substrate recognition. Commun Biol, 2, 2019
6OOP	protein B 分子名称: 1,1'-dimethyl-4,4'-bipyridin-1-ium, Multidrug transporter MdfA, PRASEODYMIUM ION 著者 Lu, M. 登録日 2019-04-23 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of an engineered multidrug transporter MdfA reveals the molecular basis for substrate recognition. Commun Biol, 2, 2019
6OOM	PROTEIN A 分子名称: LAURYL DIMETHYLAMINE-N-OXIDE, Multidrug transporter MdfA, PRASEODYMIUM ION 著者 Lu, M. 登録日 2019-04-23 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of an engineered multidrug transporter MdfA reveals the molecular basis for substrate recognition. Commun Biol, 2, 2019
6N3I	Crystal structure of a double Trp XylE mutants (G58W/L315W) 分子名称: D-xylose transporter 著者 Jiang, X, Wu, J.P, Yan, N. 登録日 2018-11-15 公開日 2019-03-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.69 Å) 主引用文献 Engineered XylE as a tool for mechanistic investigation and ligand discovery of the glucose transporters GLUTs. Cell Discov, 5, 2019
4JA3	Partially occluded inward open conformation of the xylose transporter XylE from E. coli 分子名称: CADMIUM ION, D-xylose-proton symporter, LUTETIUM (III) ION 著者 Quistgaard, E.M, Low, C, Moberg, P, Tresaugues, L, Nordlund, P. 登録日 2013-02-18 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters. Nat.Struct.Mol.Biol., 20, 2013
7CRZ	Crystal structure of human glucose transporter GLUT3 bound with C3361 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol, Solute carrier family 2, ... 著者 Yuan, Y.Y, Zhang, S, Wang, N, Jiang, X, Yan, N. 登録日 2020-08-14 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents. Proc.Natl.Acad.Sci.USA, 118, 2021
6GV1	Crystal structure of E.coli Multidrug/H+ antiporter MdfA in outward open conformation with bound Fab fragment 分子名称: Fab fragment YN1074 heavy chain, Fab fragment YN1074 light chain, Major Facilitator Superfamily multidrug/H+ antiporter MdfA from E.coli, ... 著者 Nagarathinam, K, Parthier, C, Stubbs, M.T, Tanabe, M. 登録日 2018-06-20 公開日 2018-10-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Outward open conformation of a Major Facilitator Superfamily multidrug/H+antiporter provides insights into switching mechanism. Nat Commun, 9, 2018
5C65	Structure of the human glucose transporter GLUT3 / SLC2A3 分子名称: CHOLESTEROL HEMISUCCINATE, Octyl Glucose Neopentyl Glycol, Solute carrier family 2, ... 著者 Pike, A.C.W, Quigley, A, Chu, A, Tessitore, A, Xia, X, Mukhopadhyay, S, Wang, D, Kupinska, K, Strain-Damerell, C, Chalk, R, Burgess-Brown, N.A, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) 登録日 2015-06-22 公開日 2015-07-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure of the human glucose transporter GLUT3 / SLC2A3 To Be Published
6VS0	protein B 分子名称: CHLORAMPHENICOL, Multidrug transporter MdfA, PRASEODYMIUM ION 著者 Lu, M, Lu, M.M. 登録日 2020-02-10 公開日 2020-06-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily. Sci Rep, 10, 2020
6VS2	protein D 分子名称: LAURYL DIMETHYLAMINE-N-OXIDE, Multidrug transporter MdfA, PRASEODYMIUM ION 著者 Lu, M, Lu, M.M. 登録日 2020-02-10 公開日 2020-06-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily. Sci Rep, 10, 2020
6VS1	protein C 分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, Multidrug transporter MdfA, PRASEODYMIUM ION 著者 Lu, M, Lu, M.M. 登録日 2020-02-10 公開日 2020-06-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily. Sci Rep, 10, 2020
6VRZ	protein A 分子名称: CHLORAMPHENICOL, Multidrug transporter MdfA, PRASEODYMIUM ION 著者 Lu, M, Lu, M.M. 登録日 2020-02-10 公開日 2020-06-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily. Sci Rep, 10, 2020
5EQG	Human GLUT1 in complex with inhibitor (2~{S})-3-(4-fluorophenyl)-2-[2-(3-hydroxyphenyl)ethanoylamino]-~{N}-[(1~{S})-1-phenylethyl]propanamide 分子名称: (2~{S})-3-(4-fluorophenyl)-2-[2-(3-hydroxyphenyl)ethanoylamino]-~{N}-[(1~{S})-1-phenylethyl]propanamide, Solute carrier family 2, facilitated glucose transporter member 1 著者 Kapoor, K, Finer-Moore, J, Pedersen, B.P, Caboni, L, Waight, A.B, Hillig, R, Bringmann, P, Heisler, I, Muller, T, Siebeneicher, H, Stroud, R.M. 登録日 2015-11-12 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides. Proc.Natl.Acad.Sci.USA, 113, 2016
5EQI	Human GLUT1 in complex with Cytochalasin B 分子名称: Cytochalasin B, Solute carrier family 2, facilitated glucose transporter member 1 著者 Kapoor, K, Finer-Moore, J, Pedersen, B.P, Caboni, L, Waight, A.B, Hillig, R, Bringmann, P, Heisler, I, Muller, T, Siebeneicher, H, Stroud, R.M. 登録日 2015-11-12 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.002 Å) 主引用文献 Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides. Proc.Natl.Acad.Sci.USA, 113, 2016
5EQH	Human GLUT1 in complex with inhibitor (2~{S})-3-(2-bromophenyl)-2-[2-(4-methoxyphenyl)ethanoylamino]-~{N}-[(1~{S})-1-phenylethyl]propanamide 分子名称: (2~{S})-3-(2-bromophenyl)-2-[2-(4-methoxyphenyl)ethanoylamino]-~{N}-[(1~{S})-1-phenylethyl]propanamide, Solute carrier family 2, facilitated glucose transporter member 1 著者 Kapoor, K, Finer-Moore, J, Pedersen, B.P, Caboni, L, Waight, A.B, Hillig, R, Bringmann, P, Heisler, I, Muller, T, Siebeneicher, H, Stroud, R.M. 登録日 2015-11-12 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides. Proc.Natl.Acad.Sci.USA, 113, 2016
4ZP0	Crystal structure of E. coli multidrug transporter MdfA in complex with deoxycholate 分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, LAURYL DIMETHYLAMINE-N-OXIDE, Multidrug transporter MdfA 著者 Zhang, X.C, Heng, J, Zhao, Y, Wang, X. 登録日 2015-05-07 公開日 2015-08-19 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Substrate-bound structure of the E. coli multidrug resistance transporter MdfA Cell Res., 25, 2015
4ZOW	Crystal structure of E. coli multidrug transporter MdfA in complex with chloramphenicol 分子名称: CHLORAMPHENICOL, Multidrug transporter MdfA 著者 Zhang, X.C, Heng, J, Zhao, Y, Wang, X. 登録日 2015-05-07 公開日 2015-08-19 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Substrate-bound structure of the E. coli multidrug resistance transporter MdfA Cell Res., 25, 2015
4ZP2	Crystal structure of E. coli multidrug transporter MdfA in complex with n-dodecyl-N,N-dimethylamine-N-oxide 分子名称: LAURYL DIMETHYLAMINE-N-OXIDE, Multidrug transporter MdfA 著者 Zhang, X.C, Heng, J, Zhao, Y, Wang, X. 登録日 2015-05-07 公開日 2015-08-19 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Substrate-bound structure of the E. coli multidrug resistance transporter MdfA Cell Res., 25, 2015

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