1YYF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yyf by Molmil](/molmil-images/mine/1yyf) | Correction of X-ray Intensities from an HslV-HslU co-crystal containing lattice translocation defects | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent hsl protease ATP-binding subunit hslU, ATP-dependent protease hslV | 著者 | Wang, J, Rho, S.H, Park, H.H, Eom, S.H. | 登録日 | 2005-02-24 | 公開日 | 2005-07-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (4.16 Å) | 主引用文献 | Correction of X-ray intensities from an HslV-HslU co-crystal containing lattice-translocation defects. Acta Crystallogr.,Sect.D, 61, 2005
|
|
4HSE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hse by Molmil](/molmil-images/mine/4hse) | Crystal structure of ClpB NBD1 in complex with guanidinium chloride and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Chaperone protein ClpB, ... | 著者 | Zeymer, C, Werbeck, N.D, Schlichting, I, Reinstein, J. | 登録日 | 2012-10-30 | 公開日 | 2013-01-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The molecular mechanism of hsp100 chaperone inhibition by the prion curing agent guanidinium chloride. J.Biol.Chem., 288, 2013
|
|
8OOI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ooi by Molmil](/molmil-images/mine/8ooi) | Full composite cryo-EM map of p97/VCP in ADP.Pi state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Cheng, T.C, Sakata, E, Schuetz, A.K. | 登録日 | 2023-04-05 | 公開日 | 2024-01-31 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | 主引用文献 | Characterizing ATP processing by the AAA+ protein p97 at the atomic level. Nat.Chem., 16, 2024
|
|
8OVF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ovf by Molmil](/molmil-images/mine/8ovf) | Human Mitochondrial Lon Y186F Mutant ADP Bound | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial | 著者 | Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E. | 登録日 | 2023-04-26 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (7.23 Å) | 主引用文献 | Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions. Sci Rep, 14, 2024
|
|
8OVG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ovg by Molmil](/molmil-images/mine/8ovg) | Human Mitochondrial Lon Y186E Mutant ADP Bound | 分子名称: | Lon protease homolog, mitochondrial | 著者 | Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E. | 登録日 | 2023-04-26 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (8.47 Å) | 主引用文献 | Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions. Sci Rep, 14, 2024
|
|
7SXO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sxo by Molmil](/molmil-images/mine/7sxo) | Yeast Lon (PIM1) with endogenous substrate | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ... | 著者 | Yang, J, Song, A.S, Wiseman, R.L, Lander, G.C. | 登録日 | 2021-11-24 | 公開日 | 2022-01-12 | 最終更新日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structure of hexameric yeast Lon protease (PIM1) highlights the importance of conserved structural elements. J.Biol.Chem., 298, 2022
|
|
7SWL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7swl by Molmil](/molmil-images/mine/7swl) | CryoEM structure of the N-terminal-deleted Rix7 AAA-ATPase | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Kocaman, S, Stanley, R.E, Lo, Y.H, Krahn, J, Dandey, V.P, Sobhany, M, Petrovich, M, Williams, J.G, Deterding, L.J, Borgnia, M.J, Etigunta, S. | 登録日 | 2021-11-20 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly. Pnas Nexus, 1, 2022
|
|
7T0V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7t0v by Molmil](/molmil-images/mine/7t0v) | CryoEM structure of the crosslinked Rix7 AAA-ATPase | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Kocaman, S, Stanley, R.E, Lo, Y.H, Krahn, J, Dandey, V.P, Sobhany, M, Petrovich, M, Williams, J.G, Deterding, L.J, Borgnia, M.J, Etigunta, S. | 登録日 | 2021-11-30 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | 主引用文献 | Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly. Pnas Nexus, 1, 2022
|
|
2ZAO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zao by Molmil](/molmil-images/mine/2zao) | Crystal structure of mouse SKD1/VPS4B ADP-form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Vacuolar protein sorting-associating protein 4B | 著者 | Inoue, M, Kawasaki, M, Kamikubo, H, Kataoka, M, Kato, R, Yoshimori, T, Wakatsuki, S. | 登録日 | 2007-10-08 | 公開日 | 2008-10-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B Traffic, 9, 2008
|
|
2ZAN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zan by Molmil](/molmil-images/mine/2zan) | Crystal structure of mouse SKD1/VPS4B ATP-form | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Vacuolar protein sorting-associating protein 4B | 著者 | Inoue, M, Kawasaki, M, Kamikubo, H, Kataoka, M, Kato, R, Yoshimori, T, Wakatsuki, S. | 登録日 | 2007-10-08 | 公開日 | 2008-10-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B Traffic, 9, 2008
|
|
2ZAM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zam by Molmil](/molmil-images/mine/2zam) | Crystal structure of mouse SKD1/VPS4B apo-form | 分子名称: | Vacuolar protein sorting-associating protein 4B | 著者 | Inoue, M, Kawasaki, M, Kamikubo, H, Kataoka, M, Kato, R, Yoshimori, T, Wakatsuki, S. | 登録日 | 2007-10-08 | 公開日 | 2008-10-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B Traffic, 9, 2008
|
|
3B9P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b9p by Molmil](/molmil-images/mine/3b9p) | Spastin | 分子名称: | CG5977-PA, isoform A, CHLORIDE ION | 著者 | Roll-Mecak, A, Vale, R.D. | 登録日 | 2007-11-06 | 公開日 | 2008-01-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin. Nature, 451, 2008
|
|
6W20
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6w20 by Molmil](/molmil-images/mine/6w20) | ClpAP Disengaged State bound to RepA-GFP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... | 著者 | Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. | 登録日 | 2020-03-04 | 公開日 | 2020-05-06 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
|
|
1QVR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qvr by Molmil](/molmil-images/mine/1qvr) | Crystal Structure Analysis of ClpB | 分子名称: | ClpB protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PLATINUM (II) ION | 著者 | Lee, S, Sowa, M.E, Watanabe, Y, Sigler, P.B, Chiu, W, Yoshida, M, Tsai, F.T.F. | 登録日 | 2003-08-28 | 公開日 | 2003-10-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The Structure of ClpB: A Molecular Chaperone that Rescues Proteins from an Aggregated State Cell(Cambridge,Mass.), 115, 2003
|
|
6W21
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6w21 by Molmil](/molmil-images/mine/6w21) | ClpAP Engaged2 State bound to RepA-GFP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... | 著者 | Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. | 登録日 | 2020-03-04 | 公開日 | 2020-05-13 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
|
|
1S3S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s3s by Molmil](/molmil-images/mine/1s3s) | Crystal structure of AAA ATPase p97/VCP ND1 in complex with p47 C | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin containing protein) (VCP) [Contains: Valosin], p47 protein | 著者 | Dreveny, I, Kondo, H, Uchiyama, K, Shaw, A, Zhang, X, Freemont, P.S. | 登録日 | 2004-01-14 | 公開日 | 2004-03-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47. Embo J., 23, 2004
|
|
6W22
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6w22 by Molmil](/molmil-images/mine/6w22) | ClpA Engaged1 State bound to RepA-GFP (ClpA Focused Refinement) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... | 著者 | Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. | 登録日 | 2020-03-04 | 公開日 | 2020-04-29 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
|
|
6VVO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vvo by Molmil](/molmil-images/mine/6vvo) | Structure of the human clamp loader (Replication Factor C, RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen, PCNA) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Gaubitz, C, Liu, X, Stone, N.P, Kelch, B.A. | 登録日 | 2020-02-18 | 公開日 | 2020-02-26 | 最終更新日 | 2020-03-25 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism Biorxiv, 2020
|
|
6W1Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6w1z by Molmil](/molmil-images/mine/6w1z) | ClpAP Engaged1 State bound to RepA-GFP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... | 著者 | Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. | 登録日 | 2020-03-04 | 公開日 | 2020-05-06 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
|
|
1KYI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kyi by Molmil](/molmil-images/mine/1kyi) | HslUV (H. influenzae)-NLVS Vinyl Sulfone Inhibitor Complex | 分子名称: | 4-IODO-3-NITROPHENYL ACETYL-LEUCINYL-LEUCINYL-LEUCINYL-VINYLSULFONE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent hsl protease ATP-binding subunit hslU, ... | 著者 | Sousa, M.C, Kessler, B.M, Overkleeft, H.S, McKay, D.B. | 登録日 | 2002-02-04 | 公開日 | 2002-05-15 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal Structure of HslUV Complexed with a Vinyl Sulfone Inhibitor:
Corroboration of a Proposed Mechanism of Allosteric Activation of
HslV by HslU J.Mol.Biol., 318, 2002
|
|
1R6B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1r6b by Molmil](/molmil-images/mine/1r6b) | High resolution crystal structure of ClpA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ClpA protein, MAGNESIUM ION | 著者 | Xia, D, Maurizi, M.R, Guo, F, Singh, S.K, Esser, L. | 登録日 | 2003-10-15 | 公開日 | 2004-08-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone. J.Struct.Biol., 146, 2004
|
|
1R7R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1r7r by Molmil](/molmil-images/mine/1r7r) | The crystal structure of murine p97/VCP at 3.6A | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | 著者 | Huyton, T, Pye, V.E, Briggs, L.C, Flynn, T.C, Beuron, F, Kondo, H, Ma, J, Zhang, X, Freemont, P.S. | 登録日 | 2003-10-22 | 公開日 | 2003-12-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | The crystal structure of murine p97/VCP at 3.6A J.Struct.Biol., 144, 2003
|
|
1OFI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ofi by Molmil](/molmil-images/mine/1ofi) | Asymmetric complex between HslV and I-domain deleted HslU (H. influenzae) | 分子名称: | 4-IODO-3-NITROPHENYL ACETYL-LEUCINYL-LEUCINYL-LEUCINYL-VINYLSULFONE, ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ... | 著者 | Kwon, A.R, Kessler, B.M, Overkleeft, H.S, McKay, D.B. | 登録日 | 2003-04-14 | 公開日 | 2003-07-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure and Reactivity of an Asymmetric Complex between Hslv and I-Domain Deleted Hslu, a Prokaryotic Homolog of the Eukaryotic Proteasome J.Mol.Biol., 330, 2003
|
|
1OFH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ofh by Molmil](/molmil-images/mine/1ofh) | Asymmetric complex between HslV and I-domain deleted HslU (H. influenzae) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV, ... | 著者 | Kwon, A.R, Kessler, B.M, Overkleeft, H.S, McKay, D.B. | 登録日 | 2003-04-14 | 公開日 | 2003-07-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure and Reactivity of an Asymmetric Complex between Hslv and I-Domain Deleted Hslu, a Prokaryotic Homolog of the Eukaryotic Proteasome J.Mol.Biol., 330, 2003
|
|
1NSF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nsf by Molmil](/molmil-images/mine/1nsf) | D2 HEXAMERIZATION DOMAIN OF N-ETHYLMALEIMIDE SENSITIVE FACTOR (NSF) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, N-ETHYLMALEIMIDE SENSITIVE FACTOR | 著者 | Yu, R.C, Hanson, P.I, Jahn, R, Brunger, A.T. | 登録日 | 1998-06-26 | 公開日 | 1998-11-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the ATP-dependent oligomerization domain of N-ethylmaleimide sensitive factor complexed with ATP. Nat.Struct.Biol., 5, 1998
|
|