4HSE

Crystal structure of ClpB NBD1 in complex with guanidinium chloride and ADP

Summary for 4HSE

• Entry DOI: 10.2210/pdb4hse/pdb
• Related: 1JBK 1QVR
• Descriptor: Chaperone protein ClpB, GUANIDINE, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: nucleotide binding domain, aaa+ protein, molecular chaperone, chaperone
• Biological source: Thermus thermophilus
• Cellular location: Cytoplasm (Probable): Q9RA63
• Total number of polymer chains: 1
• Total formula weight: 45565.13

Authors

Zeymer, C.,Werbeck, N.D.,Schlichting, I.,Reinstein, J. (deposition date: 2012-10-30, release date: 2013-01-30, Last modification date: 2023-09-20)

• Primary citation: Zeymer, C.,Werbeck, N.D.,Schlichting, I.,Reinstein, J.; The molecular mechanism of hsp100 chaperone inhibition by the prion curing agent guanidinium chloride.; J.Biol.Chem., 288:7065-7076, 2013; PubMed: 23341453; DOI: 10.1074/jbc.M112.432583

Experimental method

X-RAY DIFFRACTION (2.2 Å)