PDB: 106 件ウェブページステータス検索Chemie searchBIRD

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4MFL	The crystal structure of acyltransferase in complex with decanoyl-CoA and Tei pseudoaglycone 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, Putative uncharacterized protein tcp24, ... 著者 Lyu, S.Y, Liu, Y.C, Chang, C.Y, Huang, C.J, Li, T.L. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136, 2014
4MFQ	The crystal structure of acyltransferase in complex with CoA and 10C-Teicoplanin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, COENZYME A, ... 著者 Lyu, S.Y, Liu, Y.C, Chang, C.Y, Huang, C.J, Li, T.L. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136, 2014
4MFZ	The crystal structure of acyltransferase in complex with decanoyl-CoA 分子名称: Dbv8 protein, SODIUM ION, SULFATE ION, ... 著者 Lyu, S.Y, Liu, Y.C, Chang, C.Y, Huang, C.J, Li, T.L. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136, 2014
4MFJ	The crystal structure of acyltransferase 分子名称: Putative uncharacterized protein tcp24 著者 Lyu, S.Y, Liu, Y.C, Chang, C.Y, Huang, C.J, Li, T.L. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136, 2014
4MFK	The crystal structure of acyltransferase in complex with decanoyl-CoA 分子名称: Putative uncharacterized protein tcp24, SULFATE ION, decanoyl-CoA 著者 Lyu, S.Y, Liu, Y.C, Chang, C.Y, Huang, C.J, Li, T.L. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136, 2014
1LG9	Crystal structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction During Vancomycin Biosynthesis 分子名称: P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE 著者 Pylypenko, O, Zerbe, K, Vitali, F, Zhang, W, Vrijbloed, J.W, Robinson, J.A, Schlichting, I. 登録日 2002-04-15 公開日 2002-12-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction during Vancomycin Biosynthesis. J.Biol.Chem., 277, 2002
1LGF	Crystal structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction During Vancomycin Biosynthesis 分子名称: P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE 著者 Pylypenko, O, Zerbe, K, Vitali, F, Zhang, W, Vrijbloed, J.W, Robinson, J.A, Schlichting, I. 登録日 2002-04-15 公開日 2002-12-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction during Vancomycin Biosynthesis. J.Biol.Chem., 277, 2002
5M2H	Crystal structure of vancomycin-Zn(II)-citrate complex 分子名称: CITRIC ACID, HEXAETHYLENE GLYCOL, Vancomycin, ... 著者 Zarkan, A, Macklyne, H.-R, Chirgadze, D.Y, Bond, A.D, Hesketh, A.R, Hong, H.-J. 登録日 2016-10-13 公開日 2017-07-19 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Zn(II) mediates vancomycin polymerization and potentiates its antibiotic activity against resistant bacteria. Sci Rep, 7, 2017
5M2K	Crystal structure of vancomycin-Zn(II) complex 分子名称: 1,2-ETHANEDIOL, ZINC ION, vancomycin, ... 著者 Zarkan, A, Macklyne, H.-R, Chirgadze, D.Y, Bond, A.D, Hesketh, A.R, Hong, H.-J. 登録日 2016-10-13 公開日 2017-07-19 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Zn(II) mediates vancomycin polymerization and potentiates its antibiotic activity against resistant bacteria. Sci Rep, 7, 2017
1FVM	Complex of vancomycin with DI-acetyl-LYS-D-ALA-D-ALA 分子名称: DI-ACETYL-LYS-D-ALA-D-ALA, VANCOMYCIN, vancosamine-(1-2)-beta-D-glucopyranose 著者 Nitanai, Y, Kakoi, K, Aoki, K. 登録日 2000-09-20 公開日 2000-11-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structures of the Complexes between Vancomycin and Cell-Wall Precursor Analogs. J.Mol.Biol., 385, 2009
1SHO	CRYSTAL STRUCTURE OF VANCOMYCIN AT ATOMIC RESOLUTION 分子名称: ACETATE ION, CHLORIDE ION, VANCOMYCIN, ... 著者 Sheldrick, G.M. 登録日 1997-07-23 公開日 1997-12-24 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Crystal Structure of Vancomycin. Structure, 4, 1996
3VFJ	The structure of monodechloro-teicoplanin in complex with its ligand, using MBP as a ligand carrier 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, 8-METHYLNONANOIC ACID, ... 著者 Economou, N.J, Weeks, S.D, Grasty, K.C, Loll, P.J. 登録日 2012-01-09 公開日 2013-01-09 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure of the complex between teicoplanin and a bacterial cell-wall peptide: use of a carrier-protein approach. Acta Crystallogr.,Sect.D, 69, 2013
3VFK	The structure of monodechloro-teicoplanin in complex with its ligand, using ubiquitin as a ligand carrier 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, 8-METHYLNONANOIC ACID, ... 著者 Economou, N.J, Weeks, S.D, Grasty, K.C, Loll, P.J. 登録日 2012-01-09 公開日 2013-01-09 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of the complex between teicoplanin and a bacterial cell-wall peptide: use of a carrier-protein approach. Acta Crystallogr.,Sect.D, 69, 2013
1GHG	CRYSTAL STRUCTURE OF VANCOMYCIN AGLYCON 分子名称: ACETIC ACID, DIMETHYL SULFOXIDE, VANCOMYCIN AGLYCON 著者 Kaplan, J, Korty, B.D, Axelsen, P.H, Loll, P.J. 登録日 2000-12-13 公開日 2001-02-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 The Role of Sugar Residues in Molecular Recognition by Vancomycin J.Med.Chem., 44, 2001
7TTP	P450 (OxyA) from kistamicin biosynthesis, mixed heme conformation 分子名称: GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 hydroxylase 著者 Greule, A, Izore, T, Cryle, M.J. 登録日 2022-02-01 公開日 2022-05-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
7TTB	P450 (OxyA) from kistamicin biosynthesis, Y99F mutant 分子名称: GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 hydroxylase 著者 Greule, A, Izore, T, Cryle, M.J. 登録日 2022-02-01 公開日 2022-05-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.801592 Å) 主引用文献 The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
7TTQ	P450 (OxyA) from kistamicin biosynthesis, imidazole complex 分子名称: GLYCEROL, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Greule, A, Izore, T, Cryle, M.J. 登録日 2022-02-01 公開日 2022-05-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
7TTA	P450 (OxyA) from kistamicin biosynthesis, mixed heme conformation, attenuated beam 分子名称: GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 hydroxylase 著者 Greule, A, Izore, T, Cryle, M.J. 登録日 2022-02-01 公開日 2022-05-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
7TTO	P450 (OxyA) from kistamicin biosynthesis, mixed heme conformation 分子名称: PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 hydroxylase 著者 Greule, A, Izore, T, Cryle, M.J. 登録日 2022-02-01 公開日 2022-05-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
3MGB	Teg 12 Ternary Structure Complexed with PAP and the Teicoplanin Aglycone 分子名称: 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, ACETATE ION, CHLORIDE ION, ... 著者 Bick, M.J, Banik, J.J, Darst, S.A, Brady, S.F. 登録日 2010-04-05 公開日 2010-06-09 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Crystal Structures of the Glycopeptide Sulfotransferase Teg12 in a Complex with the Teicoplanin Aglycone. Biochemistry, 49, 2010
8GJ4	A1 Tei: Adenylation domain 1 core construct from teicoplanin biosynthesis 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, MbtH-like short polypeptide, ... 著者 Hansen, M.H, Cryle, M.J. 登録日 2023-03-14 公開日 2023-12-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nat Commun, 14, 2023
8GKM	A1 Leu graft + Leu: Adenylation domain 1 core construct from teicoplanin biosynthesis, leucine selection pocket graft; leucine bound 分子名称: ACETIC ACID, DI(HYDROXYETHYL)ETHER, LEUCINE, ... 著者 Hansen, M.H, Cryle, M.J. 登録日 2023-03-20 公開日 2023-12-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nat Commun, 14, 2023
8GJP	A1 Int graft: Adenylation domain 1 core construct from teicoplanin biosynthesis, intermediate selection pocket graft 分子名称: MbtH-like short polypeptide, Non-ribosomal peptide synthetase 著者 Hansen, M.H, Cryle, M.J. 登録日 2023-03-16 公開日 2023-12-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nat Commun, 14, 2023
8GIC	A1 Tei + Hpg: Adenylation domain 1 core construct from teicoplanin biosynthesis; 4-hydroxyphenylglycine bound 分子名称: (2S)-AMINO(4-HYDROXYPHENYL)ACETIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MbtH-like short polypeptide, ... 著者 Hansen, M.H, Cryle, M.J. 登録日 2023-03-14 公開日 2023-12-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides. Nat Commun, 14, 2023
3RUL	New strategy to analyze structures of glycopeptide-target complexes 分子名称: 10-METHYLUNDECANOIC ACID, 2-amino-2-deoxy-beta-D-glucopyranuronic acid, CHLORIDE ION, ... 著者 Economou, N.J, Nahoum, V, Weeks, S.D, Grasty, K.C, Loll, P.J. 登録日 2011-05-05 公開日 2012-06-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A carrier protein strategy yields the structure of dalbavancin. J.Am.Chem.Soc., 134, 2012

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