5M2K
Crystal structure of vancomycin-Zn(II) complex
Summary for 5M2K
Entry DOI | 10.2210/pdb5m2k/pdb |
Related PRD ID | PRD_000204 |
Descriptor | vancomycin, vancosamine-(1-2)-beta-D-glucopyranose, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | vancomycin, zinc, glycopeptide, antibiotic |
Biological source | Amycolatopsis orientalis |
Total number of polymer chains | 2 |
Total formula weight | 3136.18 |
Authors | Zarkan, A.,Macklyne, H.-R.,Chirgadze, D.Y.,Bond, A.D.,Hesketh, A.R.,Hong, H.-J. (deposition date: 2016-10-13, release date: 2017-07-19, Last modification date: 2020-07-29) |
Primary citation | Zarkan, A.,Macklyne, H.R.,Chirgadze, D.Y.,Bond, A.D.,Hesketh, A.R.,Hong, H.J. Zn(II) mediates vancomycin polymerization and potentiates its antibiotic activity against resistant bacteria. Sci Rep, 7:4893-4893, 2017 Cited by PubMed: 28687742DOI: 10.1038/s41598-017-04868-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1 Å) |
Structure validation
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