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1OU5
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BU of 1ou5 by Molmil
Crystal structure of human CCA-adding enzyme
分子名称: tRNA CCA-adding enzyme
著者Augustin, M.A, Reichert, A.S, Betat, H, Huber, R, Moerl, M, Steegborn, C.
登録日2003-03-24
公開日2003-05-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal Structure of the Human CCA-adding Enzyme: Insights into Template-independent Polymerization
J.Mol.Biol., 328, 2003
7Z27
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BU of 7z27 by Molmil
Crystal structure of the SPOC domain of human RBM15
分子名称: RNA-binding protein 15
著者Grishkovskaya, I, Appel, L.M, Djinovic-Carugo, K, Slade, D.
登録日2022-02-25
公開日2022-12-07
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Nat Commun, 14, 2023
5URN
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BU of 5urn by Molmil
NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the transactivation domain 1 of p65
分子名称: RNA polymerase II transcription factor B subunit 1, Transcription factor p65
著者Lecoq, L, Omichinski, J.G, Raiola, L, Cyr, N, Chabot, P, Arseneault, G, Legault, P.
登録日2017-02-11
公開日2017-03-08
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural characterization of interactions between transactivation domain 1 of the p65 subunit of NF-kappa B and transcription regulatory factors.
Nucleic Acids Res., 45, 2017
4OWR
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BU of 4owr by Molmil
Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair Rae1-Nup98
分子名称: Matrix protein, Nuclear pore complex protein Nup98-Nup96, mRNA export factor
著者Ren, Y, Quan, B, Seo, H.S, Blobel, G.
登録日2014-02-03
公開日2014-06-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair (Rae1 Nup98).
Proc.Natl.Acad.Sci.USA, 111, 2014
6G2Q
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BU of 6g2q by Molmil
Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CHCL (S-isomer), beta, gamma dTTP analogue
分子名称: CHLORIDE ION, DNA polymerase beta, Downstream Primer Strand, ...
著者Batra, V.K, Wilson, S.H.
登録日2018-03-23
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.148 Å)
主引用文献Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs.
Biochemistry, 57, 2018
2B7E
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BU of 2b7e by Molmil
First FF domain of Prp40 Yeast Protein
分子名称: Pre-mRNA processing protein PRP40
著者Gasch, A, Wiesner, S, Martin-Malpartida, P, Ramirez-Espain, X, Ruiz, L, Macias, M.J.
登録日2005-10-04
公開日2005-11-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structure of Prp40 FF1 domain and its interaction with the crn-TPR1 motif of Clf1 gives a new insight into the binding mode of FF domains.
J.Biol.Chem., 281, 2006
1TCO
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BU of 1tco by Molmil
TERNARY COMPLEX OF A CALCINEURIN A FRAGMENT, CALCINEURIN B, FKBP12 AND THE IMMUNOSUPPRESSANT DRUG FK506 (TACROLIMUS)
分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CALCIUM ION, FE (III) ION, ...
著者Griffith, J.P, Kim, J.L, Kim, E.E, Sintchak, M.D, Thomson, J.A, Fitzgibbon, M.J, Fleming, M.A, Caron, P.R, Hsiao, K, Navia, M.A.
登録日1996-08-21
公開日1997-02-12
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex.
Cell(Cambridge,Mass.), 82, 1995
4RT3
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BU of 4rt3 by Molmil
Ternary complex crystal structure of DNA polymerase Beta with (alpha, beta)-NH-(beta,gamma)-CH2-dTTP
分子名称: 2'-deoxy-5'-O-[(S)-hydroxy{[(R)-hydroxy(phosphonomethyl)phosphoryl]amino}phosphoryl]-3,4-dihydrothymidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
著者Batra, V.K, Wilson, S.H.
登録日2014-11-12
公開日2015-07-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Two Scaffolds from Two Flips: (alpha, beta)/(beta, gamma) CH2/NH "Met-Im" Analogues of dTTP.
Org.Lett., 17, 2015
8KIA
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BU of 8kia by Molmil
Tomato spotted wilt virus L protein (apo state)
分子名称: RNA-directed RNA polymerase L
著者Cao, L, Wang, X.
登録日2023-08-23
公開日2024-09-25
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure of Tomato spotted wilt virus L protein.
To Be Published
7Y5M
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BU of 7y5m by Molmil
The OTU domain of Tacheng Tick Virus 1
分子名称: RNA-directed RNA polymerase
著者Li, Z, Wang, W.J, Xiao, Y.S, Sun, L.T.
登録日2022-06-17
公開日2023-06-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The OTU domain of Tacheng Tick Virus 1
To Be Published
4C0H
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BU of 4c0h by Molmil
Extended interface between Pcf11p and Clp1p and structural basis for ATP loss in Gly135Arg point mutant
分子名称: MRNA CLEAVAGE AND POLYADENYLATION FACTOR CLP1, PCF11P
著者Dupin, A.F, Fribourg, S.
登録日2013-08-02
公開日2014-02-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for ATP loss by Clp1p in a G135R mutant protein.
Biochimie, 101, 2014
7YZV
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BU of 7yzv by Molmil
Ryegrass mottle virus serine protease domain S159A mutant
分子名称: RNA-directed RNA polymerase
著者Kalnins, G.
登録日2022-02-21
公開日2022-03-02
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献VPg Impact on Ryegrass Mottle Virus Serine-like 3C Protease Proteolysis and Structure.
Int J Mol Sci, 24, 2023
1O6W
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BU of 1o6w by Molmil
Solution Structure of the Prp40 WW Domain Pair of the Yeast Splicing Factor Prp40
分子名称: PRE-MRNA PROCESSING PROTEIN PRP40
著者Wiesner, S, Stier, G, Sattler, M, Macias, M.J.
登録日2002-10-16
公開日2002-12-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure and Ligand Recognition of the Ww Domain Pair of the Yeast Splicing Factor Prp40
J.Mol.Biol., 324, 2002
3DOM
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BU of 3dom by Molmil
Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2
分子名称: RNA polymerase II transcription factor B subunit 2, RNA polymerase II transcription factor B subunit 5
著者Kainov, D.E, Cavarelli, J, Egly, J.M, Poterszman, A.
登録日2008-07-04
公開日2008-08-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for group A trichothiodystrophy
Nat.Struct.Mol.Biol., 15, 2008
4RT2
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BU of 4rt2 by Molmil
Ternary complex crystal structure of DNA polymerase Beta with (alpha,beta)-CH2-(beta,gamma)-NH-dTTP
分子名称: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonoamino)phosphoryl]methyl}phosphoryl]-3,4-dihydrothymidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
著者Batra, V.K, Wilson, S.H.
登録日2014-11-12
公開日2015-07-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Two Scaffolds from Two Flips: (alpha, beta)/(beta, gamma) CH2/NH "Met-Im" Analogues of dTTP.
Org.Lett., 17, 2015
3DGP
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BU of 3dgp by Molmil
Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2
分子名称: RNA polymerase II transcription factor B subunit 2, RNA polymerase II transcription factor B subunit 5
著者Kainov, D.E, Cavarelli, J, Egly, J.M, Poterszman, A.
登録日2008-06-14
公開日2008-08-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for group A trichothiodystrophy
Nat.Struct.Mol.Biol., 15, 2008
4TQR
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BU of 4tqr by Molmil
Ternary complex of Y-family DNA polymerase Dpo4 with (5'S)-8,5'-Cyclo-2'-deoxyguanosine and dTTP
分子名称: 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*T)-3'), ...
著者Zhao, L.
登録日2014-06-11
公開日2015-01-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Kinetic and Structural Mechanisms of (5'S)-8,5'-Cyclo-2'-deoxyguanosine-Induced DNA Replication Stalling.
Biochemistry, 54, 2015
4TQS
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BU of 4tqs by Molmil
Ternary complex of Y-family DNA polymerase Dpo4 with (5'S)-8,5'-Cyclo-2'-deoxyguanosine and dCTP
分子名称: 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*T)-3'), ...
著者Zhao, L.
登録日2014-06-11
公開日2015-01-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Kinetic and Structural Mechanisms of (5'S)-8,5'-Cyclo-2'-deoxyguanosine-Induced DNA Replication Stalling.
Biochemistry, 54, 2015
5V5I
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BU of 5v5i by Molmil
OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.1
分子名称: RNA-directed RNA polymerase L, Ubiquitin variant CC.1
著者Khare, B, Mark, B.L.
登録日2017-03-14
公開日2017-05-10
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.1
To be published
4I1T
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BU of 4i1t by Molmil
Crystal structure of the cap-snatching endonuclease from Pichinde virus
分子名称: RNA-directed RNA polymerase L
著者Bussetta, C, Choi, K.H.
登録日2012-11-21
公開日2014-02-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the cap-snatching endonuclease from Pichinde virus, a new world arenavirus
To be Published
4KHQ
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BU of 4khq by Molmil
Ternary complex of RB69 mutant L415F wit DUMPNPP
分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ...
著者Clausen, A.R, Pedersen, L.C.
登録日2013-05-01
公開日2013-10-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.186 Å)
主引用文献Structure-function analysis of ribonucleotide bypass by B family DNA replicases.
Proc.Natl.Acad.Sci.USA, 110, 2013
6BEL
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BU of 6bel by Molmil
Ternary complex crystal structure of DNA polymerase Beta with R-isomer of beta-gamma-CHF-dCTP
分子名称: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-deoxy-5'-O-[(R)-{[(R)-[(R)-fluoro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine, CHLORIDE ION, ...
著者Batra, V.K, Wilson, S.H.
登録日2017-10-25
公開日2018-10-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs.
Biochemistry, 57, 2018
6CR3
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BU of 6cr3 by Molmil
Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CBr2, beta, gamma dATP analogue
分子名称: 2'-deoxy-5'-O-[(R)-{[(R)-[dibromo(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]adenosine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
著者Batra, V.K, Wilson, S.H.
登録日2018-03-16
公開日2018-06-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs.
Biochemistry, 57, 2018
6CTM
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BU of 6ctm by Molmil
Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CHCL(R-isomer), beta, gamma dTTP analogue
分子名称: 5'-O-[(R)-{[(R)-[(R)-chloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]thymidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
著者Batra, V.K, Wilson, S.H.
登録日2018-03-23
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs.
Biochemistry, 57, 2018
6CTN
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BU of 6ctn by Molmil
Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CFCL,beta-gamma dTTP analogue
分子名称: 5'-O-[(R)-{[(R)-[(S)-chloro(fluoro)phosphonomethyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3'), ...
著者Batra, V.K, Wilson, S.H.
登録日2018-03-23
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs.
Biochemistry, 57, 2018

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件を2024-11-06に公開中

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