PDB: 45118 件ウェブページステータス検索Chemie searchBIRD

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4J43	PylD holoenzyme 分子名称: MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PylD, ... 著者 Quitterer, F, Beck, P, Bacher, A, Groll, M. 登録日 2013-02-06 公開日 2013-06-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and Reaction Mechanism of Pyrrolysine Synthase (PylD). Angew.Chem.Int.Ed.Engl., 52, 2013
1NZX	Human mitochondrial aldehyde dehydrogenase complexed with NAD+ in the presence of low Mg2+ 分子名称: Aldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION 著者 Perez-Miller, S.J, Hurley, T.D. 登録日 2003-02-20 公開日 2003-06-24 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Coenzyme isomerization is integral to catalysis in aldehyde dehydrogenase Biochemistry, 42, 2003
4J1E	CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-Cyano-pyridine-2-carboxylic acid [3-((4S,6S)-2-amino-4-fluoromethyl-6-trifluoromethyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide 分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, N-{3-[(4S,6S)-2-amino-4-(fluoromethyl)-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide, ... 著者 Kuglstatter, A, Stihle, M. 登録日 2013-02-01 公開日 2013-05-01 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 beta-Secretase (BACE1) Inhibitors with High In Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer s Disease J.Med.Chem., 56, 2013
4J0T	CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-Ethoxy-pyridine-2-carboxylic acid [3-((R)-2-amino-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide 分子名称: 5-Ethoxy-pyridine-2-carboxylic acid [3-((R)-2-amino-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide, Beta-secretase 1, DIMETHYL SULFOXIDE, ... 著者 Kuglstatter, A, Stihle, M. 登録日 2013-01-31 公開日 2013-05-01 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 beta-Secretase (BACE1) Inhibitors with High In Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer s Disease J.Med.Chem., 56, 2013
2AMF	Crystal structure of 1-Pyrroline-5-Carboxylate Reductase from Human Pathogen Streptococcus Pyogenes 分子名称: 1-Pyrroline-5-Carboxylate reductase, PROLINE, SODIUM ION 著者 Nocek, B, Lezondra, L, Holzle, D, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2005-08-09 公開日 2005-09-27 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structures of Delta(1)-Pyrroline-5-carboxylate Reductase from Human Pathogens Neisseria meningitides and Streptococcus pyogenes J.Mol.Biol., 354, 2005
4IKB	Crystal structure of SNX11 PX domain 分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CHLORIDE ION, SODIUM ION, ... 著者 Xu, J, Xu, T, Liu, J. 登録日 2012-12-26 公開日 2013-04-24 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structure of Sorting Nexin 11 (SNX11) Reveals a Novel Extended PX Domain (PXe Domain) Critical for the Inhibition of Sorting Nexin 10 (SNX10) Induced Vacuolation to be published
4IIL	Crystal Structure of RfuA (TP0298) of T. pallidum Bound to Riboflavin 分子名称: 1,2-ETHANEDIOL, Membrane lipoprotein TpN38(b), POTASSIUM ION, ... 著者 Brautigam, C.A, Deka, R.K, Norgard, M.V. 登録日 2012-12-20 公開日 2013-02-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Evidence for an ABC-type riboflavin transporter system in pathogenic spirochetes. MBio, 4, 2013
4INB	Crystal Structure of the N-Terminal Domain of HIV-1 Capsid in Complex With benzodiazepine Inhibitor 分子名称: (3Z)-3-{[(2-methoxyethyl)amino]methylidene}-1-methyl-5-phenyl-7-(trifluoromethyl)-1H-1,5-benzodiazepine-2,4(3H,5H)-dione, Gag protein, SODIUM ION 著者 Coulombe, R. 登録日 2013-01-04 公開日 2013-02-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Monitoring Binding of HIV-1 Capsid Assembly Inhibitors Using (19) F Ligand-and (15) N Protein-Based NMR and X-ray Crystallography: Early Hit Validation of a Benzodiazepine Series. Chemmedchem, 8, 2013
2WC8	S100A12 complex with zinc in the absence of calcium 分子名称: CITRIC ACID, PROTEIN S100-A12, SODIUM ION, ... 著者 Moroz, O.V, Blagova, E.V, Wilkinson, A.J, Wilson, K.S, Bronstein, I.B. 登録日 2009-03-10 公開日 2009-06-23 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 The Crystal Structures of Human S100A12 in Apo Form and in Complex with Zinc: New Insights Into S100A12 Oligomerisation. J.Mol.Biol., 391, 2009
4GOG	Crystal structure of the GES-1 imipenem acyl-enzyme complex 分子名称: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase GES-1, IODIDE ION, ... 著者 Smith, C.A, Vakulenko, S.B, Munoz, J. 登録日 2012-08-20 公開日 2013-07-24 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Structural basis for progression toward the carbapenemase activity in the GES family of beta-lactamases. J.Am.Chem.Soc., 134, 2012
4GWE	W116L-OYE1 complexed with (R)-carvone 分子名称: (5R)-2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-one, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... 著者 Pompeu, Y.A, Stewart, J.D. 登録日 2012-09-02 公開日 2012-10-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 X‑ray Crystallography Reveals How Subtle Changes Control the Orientation of Substrate Binding in an Alkene Reductase ACS CATALYSIS, 3, 2013
4J0V	CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-Cyano-pyridine-2-carboxylic acid [3-((4R,5R)-2-amino-5-fluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide 分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, N-{3-[(4R,5R)-2-amino-5-fluoro-4-methyl-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide, ... 著者 Kuglstatter, A, Stihle, M. 登録日 2013-01-31 公開日 2013-05-01 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 beta-Secretase (BACE1) Inhibitors with High In Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer s Disease J.Med.Chem., 56, 2013
4J1I	CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-Cyano-pyridine-2-carboxylic acid [3-((4R,5R,6R)-2-amino-5-fluoro-4-methyl-6-trifluoromethyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide 分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, N-{3-[(4R,5R,6R)-2-amino-5-fluoro-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide, ... 著者 Kuglstatter, A, Stihle, M. 登録日 2013-02-01 公開日 2013-05-01 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 beta-Secretase (BACE1) Inhibitors with High In Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer s Disease J.Med.Chem., 56, 2013
4J0Y	CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-Cyano-pyridine-2-carboxylic acid [3-((4R,5S)-2-amino-5-fluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide 分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, N-{3-[(4R,5S)-2-amino-5-fluoro-4-methyl-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide, ... 著者 Kuglstatter, A, Stihle, M. 登録日 2013-01-31 公開日 2013-05-01 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 beta-Secretase (BACE1) Inhibitors with High In Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer s Disease J.Med.Chem., 56, 2013
4J1C	CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-Cyano-pyridine-2-carboxylic acid [3-((S)-2-amino-5,5-difluoro-4-fluoromethyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide 分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, N-{3-[(4S)-2-amino-5,5-difluoro-4-(fluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide, ... 著者 Kuglstatter, A, Stihle, M. 登録日 2013-02-01 公開日 2013-05-01 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 beta-Secretase (BACE1) Inhibitors with High In Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer s Disease J.Med.Chem., 56, 2013
4J3G	Crystal structure of Ribosomal-protein-alanine N-acetyltransferase from Brucella melitensis 分子名称: 1,2-ETHANEDIOL, GCN5-related N-acetyltransferase, IMIDAZOLE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-02-05 公開日 2013-03-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of Ribosomal-protein-alanine N-acetyltransferase from Brucella melitensis TO BE PUBLISHED
4J17	CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-Cyano-pyridine-2-carboxylic acid [3-((S)-2-amino-4-difluoromethyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide 分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, N-{3-[(4S)-2-amino-4-(difluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide, ... 著者 Kuglstatter, A, Stihle, M. 登録日 2013-02-01 公開日 2013-05-01 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 beta-Secretase (BACE1) Inhibitors with High In Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer s Disease J.Med.Chem., 56, 2013
4GZV	Crystal structure of a lipocalin family protein (BACOVA_00364) from Bacteroides ovatus ATCC 8483 at 1.95 A resolution 分子名称: ACETATE ION, GLYCEROL, SODIUM ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2012-09-06 公開日 2012-11-07 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of a hypothetical protein (BACOVA_00364) from Bacteroides ovatus ATCC 8483 at 1.95 A resolution To be published
2WSJ	Crystal Structure of single point mutant Glu71Ser p-coumaric Acid Decarboxylase 分子名称: BARIUM ION, CHLORIDE ION, ISOPROPYL ALCOHOL, ... 著者 Rodriguez, H, Angulo, I, De Las Rivas, B, Campillo, N, Paez, J.A, Munoz, R, Mancheno, J.M. 登録日 2009-09-07 公開日 2010-02-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 P-Coumaric Acid Decarboxylase from Lactobacillus Plantarum: Structural Insights Into the Active Site and Decarboxylation Catalytic Mechanism. Proteins, 78, 2010
4HCD	Crystal structure of D-glucarate dehydratase from agrobacterium tumefaciens complexed with magnesium 分子名称: CHLORIDE ION, Isomerase/lactonizing enzyme, MAGNESIUM ION, ... 著者 Fedorov, A.A, Fedorov, E.V, Sakai, A, Millikin, C, Gerlt, J.A, Almo, S.C. 登録日 2012-09-29 公開日 2013-10-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of D-glucarate dehydratase from agrobacterium tumefaciens complexed with magnesium To be Published
3G3J	Crystal structure of the GluR6 ligand binding domain dimer I442H K494E K665R I749L Q753K mutant with glutamate and NaCl at 1.32 Angstrom resolution 分子名称: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ... 著者 Chaudhry, C, Mayer, M.L. 登録日 2009-02-02 公開日 2009-06-02 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.321 Å) 主引用文献 Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization. Embo J., 28, 2009
4J0Z	CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-Cyano-pyridine-2-carboxylic acid [3-((4S,5R)-2-amino-5-fluoro-4-fluoromethyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide 分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, N-{3-[(4S,5R)-2-amino-5-fluoro-4-(fluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide, ... 著者 Kuglstatter, A, Stihle, M. 登録日 2013-01-31 公開日 2013-05-01 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 beta-Secretase (BACE1) Inhibitors with High In Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer s Disease J.Med.Chem., 56, 2013
4J1F	CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-Cyano-pyridine-2-carboxylic acid [3-((4S,6S)-2-amino-4-methyl-6-trifluoromethyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide 分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, N-{3-[(4S,6S)-2-amino-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide, ... 著者 Kuglstatter, A, Stihle, M. 登録日 2013-02-01 公開日 2013-05-01 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 beta-Secretase (BACE1) Inhibitors with High In Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer s Disease J.Med.Chem., 56, 2013
3GDF	Crystal structure of the NADP-dependent mannitol dehydrogenase from Cladosporium herbarum. 分子名称: Probable NADP-dependent mannitol dehydrogenase, ZINC ION 著者 Nuess, D, Goettig, P, Magler, I, Denk, U, Breitenbach, M, Schneider, P.B, Brandstetter, H, Simon-Nobbe, B. 登録日 2009-02-24 公開日 2010-05-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the NADP-dependent mannitol dehydrogenase from Cladosporium herbarum: Implications for oligomerisation and catalysis. Biochimie, 92, 2010
4J4B	PylD in complex with L-lysine-Ne-D-ornithine and NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MAGNESIUM ION, N~6~-D-ornithyl-L-lysine, ... 著者 Quitterer, F, Beck, P, Bacher, A, Groll, M. 登録日 2013-02-06 公開日 2013-06-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and Reaction Mechanism of Pyrrolysine Synthase (PylD). Angew.Chem.Int.Ed.Engl., 52, 2013

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