2AMF

Crystal structure of 1-Pyrroline-5-Carboxylate Reductase from Human Pathogen Streptococcus Pyogenes

Summary for 2AMF

Entry DOI	10.2210/pdb2amf/pdb
Related	1YQG 2AG8 2AHR
Descriptor	1-Pyrroline-5-Carboxylate reductase, SODIUM ION, PROLINE, ... (4 entities in total)
Functional Keywords	1-pyrroline-5-reductase, pyrroline-5-carboxylate reductase, pyrroline reductase, proline biosynthesis, nad(p)binding protein, rossmann fold, domain swapping, human pathogen, streptococcus pyogenes, structural genomics, mcsg, psi, protein structure initiative, midwest center for structural genomics, oxidoreductase
Biological source	Streptococcus pyogenes
Total number of polymer chains	5
Total formula weight	139291.18
Authors	Nocek, B.,Lezondra, L.,Holzle, D.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2005-08-09, release date: 2005-09-27, Last modification date: 2023-08-23)
Primary citation	Nocek, B.,Chang, C.,Li, H.,Lezondra, L.,Holzle, D.,Collart, F.,Joachimiak, A. Crystal Structures of Delta(1)-Pyrroline-5-carboxylate Reductase from Human Pathogens Neisseria meningitides and Streptococcus pyogenes J.Mol.Biol., 354:91-106, 2005 Cited by PubMed: 16233902 DOI: 10.1016/j.jmb.2005.08.036 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation