1PR2
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![BU of 1pr2 by Molmil](/molmil-images/mine/1pr2) | Escherichia coli Purine Nucleoside Phosphorylase Complexed with 9-beta-D-[2-deoxyribofuranosyl]-6-methylpurine and Phosphate/Sulfate | 分子名称: | 9-(2-DEOXY-BETA-D-RIBOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type | 著者 | Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E. | 登録日 | 2003-06-19 | 公開日 | 2003-11-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase. J.Biol.Chem., 278, 2003
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1PTW
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1Q3W
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![BU of 1q3w by Molmil](/molmil-images/mine/1q3w) | GSK-3 Beta complexed with Alsterpaullone | 分子名称: | 9-NITRO-5,12-DIHYDRO-7H-BENZO[2,3]AZEPINO[4,5-B]INDOL-6-ONE, GLYCOGEN SYNTHASE KINASE-3 BETA | 著者 | Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M. | 登録日 | 2003-08-01 | 公開日 | 2003-10-21 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors J.Mol.Biol., 333, 2003
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1Q6S
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![BU of 1q6s by Molmil](/molmil-images/mine/1q6s) | THE STRUCTURE OF PHOSPHOTYROSINE PHOSPHATASE 1B IN COMPLEX WITH COMPOUND 9 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 6-[4-((2R)-2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-3-{4-[DIFLUORO(PHOSPHONO)METHYL]PHENYL}-2-PHENYLPROPYL)PHENYL]-2-METHYLQUINOLIN-8-YLPHOSPHONIC ACID, CHLORIDE ION, ... | 著者 | Scapin, G, Patel, S.B, Becker, J.W, Wang, Q, Desponts, C, Waddleton, D, Skorey, K, Cromlish, W, Bayly, C, Therien, M, Gauthier, J.Y, Li, C.S, Lau, C.K, Ramachandran, C, Kennedy, B.P, Asante-Appiah, E. | 登録日 | 2003-08-13 | 公開日 | 2003-09-30 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Structural Basis for the Selectivity of Benzotriazole Inhibitors of Ptp1B Biochemistry, 42, 2003
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1Q8T
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![BU of 1q8t by Molmil](/molmil-images/mine/1q8t) | The Catalytic Subunit of cAMP-dependent Protein Kinase (PKA) in Complex with Rho-kinase Inhibitor Y-27632 | 分子名称: | (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... | 著者 | Breitenlechner, C, Gassel, M, Hidaka, H, Kinzel, V, Huber, R, Engh, R.A, Bossemeyer, D. | 登録日 | 2003-08-22 | 公開日 | 2003-12-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity. Structure, 11, 2003
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1QYD
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![BU of 1qyd by Molmil](/molmil-images/mine/1qyd) | Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases, and their relationship to isoflavone reductases | 分子名称: | pinoresinol-lariciresinol reductase | 著者 | Min, T, Kasahara, H, Bedgar, D.L, Youn, B, Lawrence, P.K, Gang, D.R, Halls, S.C, Park, H, Hilsenbeck, J.L, Davin, L.B, Kang, C. | 登録日 | 2003-09-10 | 公開日 | 2003-11-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases and their relationship to isoflavone reductases. J.Biol.Chem., 278, 2003
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1QNX
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![BU of 1qnx by Molmil](/molmil-images/mine/1qnx) | Ves v 5, an allergen from Vespula vulgaris venom | 分子名称: | SODIUM ION, VES V 5 | 著者 | Henriksen, A, Gajhede, M, Spangfort, M.D. | 登録日 | 1999-10-25 | 公開日 | 2000-10-26 | 最終更新日 | 2018-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Major Venom Allergen of Yellow Jackets, Ves V 5: Structural Characterization of a Pathogenesis-Related Protein Superfamily. Proteins: Struct.,Funct., Genet., 45, 2001
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1OAL
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![BU of 1oal by Molmil](/molmil-images/mine/1oal) | Active site copper and zinc ions modulate the quaternary structure of prokaryotic Cu,Zn superoxide dismutase | 分子名称: | COPPER (II) ION, SUPEROXIDE DISMUTASE, ZINC ION | 著者 | Cioni, P, Pesce, A, Rocca, B.M.D, Castellifalconiparrilli, L, Bolognesi, M, Strambini, G, Desideri, A. | 登録日 | 2003-01-15 | 公開日 | 2003-02-27 | 最終更新日 | 2019-10-09 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Active-Site Copper and Zinc Ions Modulate the Quaternary Structure of Prokaryotic Cu,Zn Superoxide Dismutase J.Mol.Biol., 326, 2003
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1PR4
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![BU of 1pr4 by Molmil](/molmil-images/mine/1pr4) | Escherichia coli Purine Nucleoside Phosphorylase Complexed with 9-beta-D-ribofuranosyl-6-methylthiopurine and Phosphate/Sulfate | 分子名称: | 2-HYDROXYMETHYL-5-(6-METHYLSULFANYL-PURIN-9-YL)-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type | 著者 | Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E. | 登録日 | 2003-06-19 | 公開日 | 2003-11-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase. J.Biol.Chem., 278, 2003
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1PPO
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![BU of 1ppo by Molmil](/molmil-images/mine/1ppo) | DETERMINATION OF THE STRUCTURE OF PAPAYA PROTEASE OMEGA | 分子名称: | MERCURY (II) ION, PROTEASE OMEGA | 著者 | Pickersgill, R.W, Rizkallah, P.J, Harris, G.W, Goodenough, P.W. | 登録日 | 1991-07-12 | 公開日 | 1993-10-31 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Determination of the Structure of Papaya Protease Omega Acta Crystallogr.,Sect.B, 47, 1991
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1PUO
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![BU of 1puo by Molmil](/molmil-images/mine/1puo) | Crystal structure of Fel d 1- the major cat allergen | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Major allergen I polypeptide, fused chain 2, ... | 著者 | Kaiser, L, Gronlund, H, Sandalova, T, Ljunggren, H.G, van Hage-Hamsten, M, Achour, A, Schneider, G. | 登録日 | 2003-06-25 | 公開日 | 2003-10-14 | 最終更新日 | 2019-07-03 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The crystal structure of the major cat allergen Fel d 1, a member of the secretoglobin family. J.Biol.Chem., 278, 2003
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1PW7
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![BU of 1pw7 by Molmil](/molmil-images/mine/1pw7) | Crystal Structure of E. coli purine nucleoside phosphorylase complexed with 9-beta-D-arabinofuranosyladenine and sulfate/phosphate | 分子名称: | 2-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type | 著者 | Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E. | 登録日 | 2003-06-30 | 公開日 | 2003-11-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase. J.Biol.Chem., 278, 2003
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1Q4J
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1Q4X
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![BU of 1q4x by Molmil](/molmil-images/mine/1q4x) | Crystal Structure of Human Thyroid Hormone Receptor beta LBD in complex with specific agonist GC-24 | 分子名称: | Thyroid hormone receptor beta-1, [4-(3-BENZYL-4-HYDROXYBENZYL)-3,5-DIMETHYLPHENOXY]ACETIC ACID | 著者 | Borngraeber, S, Budny, M.J, Chiellini, G, Cunha-Lima, S.T, Togashi, M, Webb, P, Baxter, J.D, Scanlan, T.S, Fletterick, R.J. | 登録日 | 2003-08-04 | 公開日 | 2004-02-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor. Proc.Natl.Acad.Sci.USA, 100, 2003
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1PXH
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![BU of 1pxh by Molmil](/molmil-images/mine/1pxh) | Crystal structure of protein tyrosine phosphatase 1B with potent and selective bidentate inhibitor compound 2 | 分子名称: | ACETIC ACID, MAGNESIUM ION, N-{1-[5-(1-CARBAMOYL-2-MERCAPTO-ETHYLCARBAMOYL)-PENTYLCARBAMOYL]-2-[4-(DIFLUORO-PHOSPHONO-METHYL)-PHENYL]-ETHYL}-3-{2-[4-(DIFLUORO-PHOSPHONO-METHYL)-PHENYL]-ACETYLAMINO}-SUCCINAMIC ACID, ... | 著者 | Sun, J.P, Fedorov, A, Lee, S.Y, Guo, X.L, Shen, K, Lawrence, D.S, Almo, S.C, Zhang, Z.Y. | 登録日 | 2003-07-04 | 公開日 | 2003-08-12 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor. J.Biol.Chem., 278, 2003
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1PR1
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![BU of 1pr1 by Molmil](/molmil-images/mine/1pr1) | Escherichia coli Purine Nucleoside Phosphorylase Complexed with Formycin B and Phosphate/Sulfate | 分子名称: | FORMYCIN B, PHOSPHATE ION, Purine nucleoside phosphorylase | 著者 | Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E. | 登録日 | 2003-06-19 | 公開日 | 2003-11-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase. J.Biol.Chem., 278, 2003
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1Q4L
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![BU of 1q4l by Molmil](/molmil-images/mine/1q4l) | GSK-3 Beta complexed with Inhibitor I-5 | 分子名称: | 2-CHLORO-5-[4-(3-CHLORO-PHENYL)-2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-3-YLAMINO]-BENZOIC ACID, GLYCOGEN SYNTHASE KINASE-3 BETA | 著者 | Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M. | 登録日 | 2003-08-04 | 公開日 | 2003-10-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors J.Mol.Biol., 333, 2003
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1QX8
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![BU of 1qx8 by Molmil](/molmil-images/mine/1qx8) | Crystal structure of a five-residue deletion mutant of the Rop protein | 分子名称: | Regulatory protein ROP | 著者 | Glykos, N.M, Vlassi, M, Papanikolaou, Y, Kotsifaki, D, Cesareni, G, Kokkinidis, M. | 登録日 | 2003-09-04 | 公開日 | 2004-09-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Loopless Rop: structure and dynamics of an engineered homotetrameric variant of the repressor of primer protein. Biochemistry, 45, 2006
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1R0A
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![BU of 1r0a by Molmil](/molmil-images/mine/1r0a) | Crystal structure of HIV-1 reverse transcriptase covalently tethered to DNA template-primer solved to 2.8 angstroms | 分子名称: | 5'-D(*A*TP*GP*CP*AP*TP*CP*GP*GP*CP*GP*CP*TP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*GP*GP*T)-3', 5'-D(*C*CP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*AP*GP*CP*GP*CP*CP*GP*(2DA))-3', GLYCEROL, ... | 著者 | Tuske, S, Ding, J, Arnold, E. | 登録日 | 2003-09-19 | 公開日 | 2004-08-03 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Nonnucleoside inhibitor binding affects the interactions of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase with DNA. J.Virol., 78, 2004
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1HVR
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![BU of 1hvr by Molmil](/molmil-images/mine/1hvr) | RATIONAL DESIGN OF POTENT, BIOAVAILABLE, NONPEPTIDE CYCLIC UREAS AS HIV PROTEASE INHIBITORS | 分子名称: | HIV-1 PROTEASE, [4R-(4ALPHA,5ALPHA,6BETA,7BETA)]-HEXAHYDRO-5,6-DIHYDROXY-1,3-BIS[2-NAPHTHYL-METHYL]-4,7-BIS(PHENYLMETHYL)-2H-1,3-DIAZEPIN-2-ONE | 著者 | Chang, C.-H. | 登録日 | 1994-02-14 | 公開日 | 1995-01-26 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors. Science, 263, 1994
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1EHW
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![BU of 1ehw by Molmil](/molmil-images/mine/1ehw) | HUMAN NUCLEOSIDE DIPHOSPHATE KINASE 4 | 分子名称: | NUCLEOSIDE DIPHOSPHATE KINASE, SULFATE ION | 著者 | Milon, L, Meyer, P, Chiadmi, M, Munier, A, Johansson, M, Karlsson, A, Lascu, I, Capeau, J, Janin, J, Lacombe, M.-L. | 登録日 | 2000-02-23 | 公開日 | 2000-05-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase. J.Biol.Chem., 275, 2000
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1HW8
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![BU of 1hw8 by Molmil](/molmil-images/mine/1hw8) | COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH COMPACTIN (ALSO KNOWN AS MEVASTATIN) | 分子名称: | (3R,5R)-3,5-dihydroxy-7-[(1S,2S,8S,8aR)-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]h eptanoic acid, ADENOSINE-5'-DIPHOSPHATE, HMG-COA REDUCTASE | 著者 | Istvan, E.S, Deisenhofer, J. | 登録日 | 2001-01-09 | 公開日 | 2001-05-11 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural mechanism for statin inhibition of HMG-CoA reductase. Science, 292, 2001
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1EXX
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![BU of 1exx by Molmil](/molmil-images/mine/1exx) | ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE INACTIVE S-ENANTIOMER BMS270395. | 分子名称: | 3-FLUORO-4-[2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8,-TETRAHYDRO-NAPHTALEN-2-YL)-ACETYLAMINO]-BENZOIC ACID, DODECYL-ALPHA-D-MALTOSIDE, RETINOIC ACID RECEPTOR GAMMA-2 | 著者 | Klaholz, B.P, Mitschler, A, Belema, M, Zusi, C, Moras, D, Structural Proteomics in Europe (SPINE) | 登録日 | 2000-05-05 | 公開日 | 2000-06-09 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma. Proc.Natl.Acad.Sci.USA, 97, 2000
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1HWL
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1EPQ
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![BU of 1epq by Molmil](/molmil-images/mine/1epq) | ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH PD-133,450 (SOT PHE GLY+SCC GCL) | 分子名称: | ENDOTHIAPEPSIN, N-[(1S)-2-{[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino}-1-(ethylsulfanyl)-2-oxoethyl]-Nalpha-(morpholin-4-ylsulfonyl)-L-phenylalaninamide, SULFATE ION | 著者 | Dealwis, C, Cooper, J.B, Blundell, T.L. | 登録日 | 1994-07-27 | 公開日 | 1994-12-20 | 最終更新日 | 2020-05-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Analyses of ligand binding in five endothiapepsin crystal complexes and their use in the design and evaluation of novel renin inhibitors. J.Med.Chem., 36, 1993
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