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2Q63
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HIV-1 PR mutant in complex with nelfinavir
分子名称: 2-[2-HYDROXY-3-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-4-PHENYL SULFANYL-BUTYL]-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID TERT-BUTYLAMIDE, PROTEASE RETROPEPSIN
著者Rezacova, P, Kozisek, M, Saskova, K, Brynda, J, Konvalinka, J.
登録日2007-06-04
公開日2008-02-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular analysis of the HIV-1 resistance development: enzymatic activities, crystal structures, and thermodynamics of nelfinavir-resistant HIV protease mutants
J.Mol.Biol., 374, 2007
2Q64
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HIV-1 PR mutant in complex with nelfinavir
分子名称: 2-[2-HYDROXY-3-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-4-PHENYL SULFANYL-BUTYL]-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID TERT-BUTYLAMIDE, PROTEASE RETROPEPSIN
著者Rezacova, P, Kozisek, M, Saskova, K, Brynda, J, Konvalinka, J.
登録日2007-06-04
公開日2008-02-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular analysis of the HIV-1 resistance development: enzymatic activities, crystal structures, and thermodynamics of nelfinavir-resistant HIV protease mutants
J.Mol.Biol., 374, 2007
2Q66
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Structure of Yeast Poly(A) Polymerase with ATP and oligo(A)
分子名称: 1,2-ETHANEDIOL, 5'-R(P*AP*AP*AP*AP*A)-3', ADENOSINE-5'-TRIPHOSPHATE, ...
著者Bohm, A, Balbo, P.
登録日2007-06-04
公開日2007-08-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mechanism of poly(A) polymerase: structure of the enzyme-MgATP-RNA ternary complex and kinetic analysis.
Structure, 15, 2007
2Q67
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BU of 2q67 by Molmil
Crystal Structure of Nak channel D66A mutant
分子名称: CALCIUM ION, Potassium channel protein, SODIUM ION
著者Alam, A, Shi, N, Jiang, Y.
登録日2007-06-04
公開日2007-10-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insight into Ca2+ specificity in tetrameric cation channels.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q68
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Crystal Structure of Nak channel D66A, S70E double mutants
分子名称: CALCIUM ION, Potassium channel protein, SODIUM ION
著者Alam, A, Shi, N, Jiang, Y.
登録日2007-06-04
公開日2007-10-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insight into Ca2+ specificity in tetrameric cation channels.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q69
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Crystal Structure of Nak channel D66N mutant
分子名称: CALCIUM ION, Potassium channel protein, SODIUM ION
著者Alam, A, Shi, N, Jiang, Y.
登録日2007-06-04
公開日2007-10-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insight into Ca2+ specificity in tetrameric cation channels.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q6A
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BU of 2q6a by Molmil
Crystal Structure of Nak channel D66E mutant
分子名称: CALCIUM ION, Potassium channel protein, SODIUM ION
著者Alam, A, Shi, N, Jiang, Y.
登録日2007-06-04
公開日2007-10-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insight into Ca2+ specificity in tetrameric cation channels.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q6B
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Design and synthesis of novel, conformationally restricted HMG-COA reductase inhibitors
分子名称: (3R,5R)-7-[3-(4-FLUOROPHENYL)-1-ISOPROPYL-8-OXO-7-PHENYL-1,4,5,6,7,8-HEXAHYDROPYRROLO[2,3-C]AZEPIN-2-YL]-3,5-DIHYDROXYHEPTANOIC ACID, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION
著者Pavlovsky, A, Pfefferkorn, J.A, Harris, M.S, Finzel, B.C.
登録日2007-06-04
公開日2007-07-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2Q6C
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BU of 2q6c by Molmil
Design and synthesis of novel, conformationally restricted HMG-COA reductase inhibitors
分子名称: (3R,5R)-7-[1-(4-FLUOROPHENYL)-3-ISOPROPYL-4-OXO-5-PHENYL-4,5-DIHYDRO-3H-PYRROLO[2,3-C]QUINOLIN-2-YL]-3,5-DIHYDROXYHEPTANOIC ACID, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION
著者Pavlovsky, A, Pfefferkorn, J.A, Harris, M.S, Finzel, B.C.
登録日2007-06-04
公開日2007-07-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2Q6D
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BU of 2q6d by Molmil
Crystal structure of infectious bronchitis virus (IBV) main protease
分子名称: Infectious bronchitis virus (IBV) main protease
著者Xue, X.Y, Yang, H.T, Xue, F, Bartlam, M, Rao, Z.H.
登録日2007-06-04
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design.
J.Virol., 82, 2008
2Q6E
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BU of 2q6e by Molmil
Crystal structure of glucuronate isomerase from Bacillus halodurans complexed with Zn
分子名称: BH0493 protein, CHLORIDE ION, SODIUM ION, ...
著者Fedorov, A.A, Fedorov, E.V, Patskovsky, Y, Toro, R, Sauder, J.M, Burley, S.K, Rauschel, F.M, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-06-05
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of glucuronate isomerase from Bacillus halodurans complexed with Zn.
To be Published
2Q6F
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Crystal structure of infectious bronchitis virus (IBV) main protease in complex with a Michael acceptor inhibitor N3
分子名称: Infectious bronchitis virus (IBV) main protease, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
著者Xue, X.Y, Yang, H.T, Xue, F, Bartlam, M, Rao, Z.H.
登録日2007-06-05
公開日2008-02-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design.
J.Virol., 82, 2008
2Q6G
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BU of 2q6g by Molmil
Crystal structure of SARS-CoV main protease H41A mutant in complex with an N-terminal substrate
分子名称: Polypeptide chain, severe acute respiratory syndrome coronavirus (SARS-CoV)
著者Xue, X.Y, Yang, H.T, Xue, F, Bartlam, M, Rao, Z.H.
登録日2007-06-05
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design.
J.Virol., 82, 2008
2Q6H
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BU of 2q6h by Molmil
Crystal Structure Analysis of LeuT complexed with L-leucine, sodium, and clomipramine
分子名称: 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, LEUCINE, SODIUM ION, ...
著者Singh, S.K, Yamashita, A, Gouaux, E.
登録日2007-06-05
公開日2007-08-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Antidepressant binding site in a bacterial homologue of neurotransmitter transporters.
Nature, 448, 2007
2Q6I
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salL with ClDA and LMet
分子名称: 5'-CHLORO-5'-DEOXYADENOSINE, DI(HYDROXYETHYL)ETHER, Hypothetical protein, ...
著者Noel, J.P, Pojer, F.
登録日2007-06-05
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery and characterization of a marine bacterial SAM-dependent chlorinase
Nat.Chem.Biol., 4, 2008
2Q6J
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Crystal Structure of Estrogen Receptor alpha Complexed to a B-N Substituted Ligand
分子名称: 4-[(DIMESITYLBORYL)(2,2,2-TRIFLUOROETHYL)AMINO]PHENOL, Estrogen receptor, GRIP peptide
著者Zhou, H, Nettles, K.W, Bruning, J.B, Kim, Y, Joachimiak, A, Sharma, S, Carlson, K.E, Stossi, F, Katzenellenbogen, B.S, Greene, G.L, Katzenellenbogen, J.A.
登録日2007-06-05
公開日2007-06-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands
Chem.Biol., 14, 2007
2Q6K
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BU of 2q6k by Molmil
SalL with adenosine
分子名称: ADENOSINE, DI(HYDROXYETHYL)ETHER, chlorinase
著者Pojer, F, Noel, J.P.
登録日2007-06-05
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Discovery and characterization of a marine bacterial SAM-dependent chlorinase
Nat.Chem.Biol., 4, 2008
2Q6L
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BU of 2q6l by Molmil
SalL double mutant Y70T/G131S with CLDA and L-MET
分子名称: 5'-CHLORO-5'-DEOXYADENOSINE, Hypothetical protein, METHIONINE
著者Pojer, F, Noel, J.P.
登録日2007-06-05
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Discovery and characterization of a marine bacterial SAM-dependent chlorinase
Nat.Chem.Biol., 4, 2008
2Q6M
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BU of 2q6m by Molmil
Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with the PJ34 inhibitor
分子名称: Cholix toxin, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
著者Merrill, A.R, Jorgensen, R.
登録日2007-06-05
公開日2008-02-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Cholix Toxin, a Novel ADP-ribosylating Factor from Vibrio cholerae.
J.Biol.Chem., 283, 2008
2Q6N
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BU of 2q6n by Molmil
Structure of Cytochrome P450 2B4 with Bound 1-(4-cholorophenyl)imidazole
分子名称: 1-(4-CHLOROPHENYL)-1H-IMIDAZOLE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE
著者Zhao, Y, Sun, L, Muralidhara, B.K, Kumar, S, White, M.A, Stout, C.D, Halpert, J.R.
登録日2007-06-05
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural and thermodynamic consequences of 1-(4-chlorophenyl)imidazole binding to cytochrome P450 2B4.
Biochemistry, 46, 2007
2Q6O
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SalL-Y70T with SAM and Cl
分子名称: CHLORIDE ION, Hypothetical Protein, S-ADENOSYLMETHIONINE
著者Noel, J.P, Pojer, F.
登録日2007-06-05
公開日2007-12-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery and characterization of a marine bacterial SAM-dependent chlorinase
Nat.Chem.Biol., 4, 2008
2Q6P
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The Chemical Control of Protein Folding: Engineering a Superfolder Green Fluorescent Protein
分子名称: Green fluorescent protein mutant 3
著者Steiner, T, Hess, P, Bae, J.H, Wiltschi, B, Moroder, L, Budisa, N.
登録日2007-06-05
公開日2007-06-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Synthetic biology of proteins: tuning GFPs folding and stability with fluoroproline.
Plos One, 3, 2008
2Q6Q
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Crystal structure of Spc42p, a critical component of spindle pole body in budding yeast
分子名称: CHLORIDE ION, COBALT (II) ION, Spindle pole body component SPC42
著者Malashkevich, V.N, Newman, J.R, Kim, P.S.
登録日2007-06-05
公開日2008-05-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Analysis of coiled-coil interactions between core proteins of the spindle pole body.
Biochemistry, 47, 2008
2Q6R
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Crystal structure of PPAR gamma complexed with partial agonist SF147
分子名称: 5-CHLORO-1-(3-METHOXYBENZYL)-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID, Peroxisome Proliferator-Activated Receptor gamma
著者Bruning, J.B, Nettles, K.W.
登録日2007-06-01
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.407 Å)
主引用文献Partial Agonists Activate PPARgamma Using a Helix 12 Independent Mechanism
Structure, 15, 2007
2Q6S
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2.4 angstrom crystal structure of PPAR gamma complexed to BVT.13 without co-activator peptides
分子名称: 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID, Peroxisome Proliferator-Activated Receptor gamma
著者Bruning, J.B, Nettles, K.W.
登録日2007-06-01
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Partial Agonists Activate PPARgamma Using a Helix 12 Independent Mechanism
Structure, 15, 2007

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