PDB: 6545 件ウェブページステータス検索Chemie searchBIRD

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5QPZ	PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000524a 分子名称: 1-[2-methyl-1,3-bis(oxidanyl)propan-2-yl]-3-phenyl-urea, ACETATE ION, Farnesyl diphosphate synthase, ... 著者 Petrick, J.K, Nelson, E.R, Muenzker, L, Krojer, T, Douangamath, A, Brandao-Neto, J, von Delft, F, Dekker, C, Jahnke, W. 登録日 2019-03-12 公開日 2020-04-29 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library To Be Published
7BUR	Chalcone synthase from Glycine max (L.) Merr (soybean) complexed with naringenin 分子名称: CITRIC ACID, Chalcone synthase 1, NARINGENIN 著者 Imaizumi, R, Mameda, R, Takeshita, K, Waki, T, Kubo, H, Sakai, N, Nakata, S, Takahashi, S, Kataoka, K, Yamamoto, M, Yamashita, S, Nakayama, T. 登録日 2020-04-08 公開日 2020-08-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Crystal structure of chalcone synthase, a key enzyme for isoflavonoid biosynthesis in soybean. Proteins, 2020
3N6K	Human FPPS complex with NOV_823 分子名称: 1-(carboxymethyl)-1H-benzo[g]indole-2-carboxylic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION 著者 Rondeau, J.-M. 登録日 2010-05-26 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
2VI7	Structure of a Putative Acetyltransferase (PA1377)from Pseudomonas aeruginosa 分子名称: ACETYLTRANSFERASE PA1377, AZIDE ION, GLYCEROL, ... 著者 Davies, A.M, Tata, R, Chauviac, F.X, Sutton, B.J, Brown, P.R. 登録日 2007-11-28 公開日 2008-05-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure of a Putative Acetyltransferase (Pa1377) from Pseudomonas Aeruginosa. Acta Crystallogr.,Sect.F, 64, 2008
7KWH	Spermidine N-acetyltransferase SpeG K23-Y30 chimera from Vibrio cholerae and hSSAT 分子名称: PHOSPHATE ION, Spermidine N(1)-acetyltransferase 著者 Le, V.T.B, Tsimbalyuk, S, Lim, E.Q, Solis, A, Gawat, D, Boeck, P, Renolo, R, Forwood, J.K. 登録日 2020-12-01 公開日 2020-12-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The Vibrio cholerae SpeG Spermidine/Spermine N -Acetyltransferase Allosteric Loop and beta 6-beta 7 Structural Elements Are Critical for Kinetic Activity. Front Mol Biosci, 8, 2021
5QTE	T. brucei FPPS in complex with CID 4563894 分子名称: (4S)-3-(4-chlorobenzene-1-carbonyl)-1,3-thiazolidine-4-carboxylic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ... 著者 Muenzker, L, Petrick, J.K, Schleberger, C, Cornaciu, I, Marquez, J.A, Jahnke, W. 登録日 2019-08-09 公開日 2020-10-07 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.072 Å) 主引用文献 T. brucei FPPS in complex with CID 4563894 To Be Published
5KSX	Crystal structure of human FPPS in complex with an allosteric inhibitor AM-02-072 分子名称: Farnesyl pyrophosphate synthase, PHOSPHATE ION, [[(2~{S})-2-[[6-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]amino]-3-phenyl-propanoyl]amino]phosphonic acid 著者 Park, J, Matralis, A, Tsantrizos, Y.S, Berghuis, A.M. 登録日 2016-07-10 公開日 2017-03-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. J. Med. Chem., 60, 2017
4DXJ	Crystal structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-propylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+ 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Aripirala, S, Amzel, L.M, Gabelli, S.B. 登録日 2012-02-27 公開日 2013-01-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase. J.Med.Chem., 55, 2012
4E0U	Crystal structure of CdpNPT in complex with thiolodiphosphate and (S)-benzodiazependione 分子名称: (3S)-3-(1H-indol-3-ylmethyl)-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione, 1,2-ETHANEDIOL, Cyclic dipeptide N-prenyltransferase, ... 著者 Schuller, J.M, Zocher, G, Stehle, T. 登録日 2012-03-05 公開日 2012-05-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure and catalytic mechanism of a cyclic dipeptide prenyltransferase with broad substrate promiscuity. J.Mol.Biol., 422, 2012
5US1	Crystal structure of aminoglycoside acetyltransferase AAC(2')-Ia in complex with N2'-acetylgentamicin C1A and coenzyme A 分子名称: (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-(acetylamino)-6-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranoside, ACETYL COENZYME *A, Aminoglycoside 2'-N-acetyltransferase, ... 著者 Stogios, P.J, Evdokimova, E, Xu, Z, Wawrzak, Z, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-02-13 公開日 2017-03-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes. ACS Infect Dis, 4, 2018
5QPE	PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000295a 分子名称: ACETATE ION, Farnesyl diphosphate synthase, SULFATE ION, ... 著者 Petrick, J.K, Nelson, E.R, Muenzker, L, Krojer, T, Douangamath, A, Brandao-Neto, J, von Delft, F, Dekker, C, Jahnke, W. 登録日 2019-03-12 公開日 2020-04-29 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library To Be Published
5QPY	PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000449a 分子名称: 1-ethyl-N-[(4-fluorophenyl)methyl]-1H-pyrazole-4-carboxamide, ACETATE ION, Farnesyl diphosphate synthase, ... 著者 Petrick, J.K, Nelson, E.R, Muenzker, L, Krojer, T, Douangamath, A, Brandao-Neto, J, von Delft, F, Dekker, C, Jahnke, W. 登録日 2019-03-12 公開日 2020-04-29 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library To Be Published
5QT4	T. brucei FPPS in complex with CID 3599333 分子名称: 1-[3-(4-chlorophenoxy)propyl]-1H-imidazole, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... 著者 Muenzker, L, Petrick, J.K, Schleberger, C, Jahnke, W. 登録日 2019-08-07 公開日 2020-10-07 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.324 Å) 主引用文献 T. brucei FPPS in complex with CID 3599333 To Be Published
7W93	Crystal structure of E.coli pseudouridine kinase PsuK complexed with N1-methyl-pseudouridine 分子名称: 5-[(2S,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-1-methyl-pyrimidine-2,4-dione, POTASSIUM ION, PfkB domain protein 著者 Li, K.J, Li, X.J, Wu, B.X. 登録日 2021-12-09 公開日 2022-06-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure Characterization of Escherichia coli Pseudouridine Kinase PsuK. Front Microbiol, 13, 2022
5QPF	PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000478a 分子名称: 2-(4-methylpiperazin-1-yl)-1,3-benzothiazole, ACETATE ION, Farnesyl diphosphate synthase, ... 著者 Petrick, J.K, Nelson, E.R, Muenzker, L, Krojer, T, Douangamath, A, Brandao-Neto, J, von Delft, F, Dekker, C, Jahnke, W. 登録日 2019-03-12 公開日 2020-04-29 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library To Be Published
5QPR	PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with XST00001145b 分子名称: 1-phenylmethoxyurea, ACETATE ION, Farnesyl diphosphate synthase, ... 著者 Petrick, J.K, Nelson, E.R, Muenzker, L, Krojer, T, Douangamath, A, Brandao-Neto, J, von Delft, F, Dekker, C, Jahnke, W. 登録日 2019-03-12 公開日 2020-04-29 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library To Be Published
5QQ5	PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with PKTTA024495b 分子名称: 1-methyl-N-(3-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, ACETATE ION, Farnesyl diphosphate synthase, ... 著者 Petrick, J.K, Nelson, E.R, Muenzker, L, Krojer, T, Douangamath, A, Brandao-Neto, J, von Delft, F, Dekker, C, Jahnke, W. 登録日 2019-03-12 公開日 2020-04-29 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library To Be Published
6TDF	Crystal structure of Aspergillus fumigatus Glucosamine-6-phosphate N-acetyltransferase 1 in complex with compound 3 分子名称: 2-[[3,5-bis(chloranyl)-4-(4~{H}-1,2,4-triazol-3-yl)phenyl]-(2-hydroxyethyl)amino]ethanol, 6-O-phosphono-alpha-D-glucopyranose, ACETYL COENZYME *A, ... 著者 Raimi, O.G, Stanley, M, Lockhart, D. 登録日 2019-11-08 公開日 2020-04-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Targeting a critical step in fungal hexosamine biosynthesis. J.Biol.Chem., 295, 2020
7VYU	Crystal structure of NatS 分子名称: 3-oxoacyl-ACP synthase 著者 Yu, Y, He, C, Wu, L, Zhang, Y. 登録日 2021-11-15 公開日 2022-08-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of NatS To Be Published
5GM2	Crystal structure of methyltransferase TleD complexed with SAH and teleocidin A1 分子名称: (2S,5S)-9-[(3R)-3,7-dimethylocta-1,6-dien-3-yl]-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one, O-methylransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Yu, F, Li, M.J, Xu, C.Y, Zhou, H, Sun, B, Wang, Z.J, Xu, Q, Xie, M.Y, Zuo, G, Huang, P, Wang, Q.S, He, J.H. 登録日 2016-07-12 公開日 2016-09-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure and enantioselectivity of terpene cyclization in SAM-dependent methyltransferase TleD Biochem.J., 473, 2016
5QT6	T. brucei FPPS in complex with CID 112445 分子名称: 6-methyl-~{N}-(phenylmethyl)pyridin-2-amine, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... 著者 Muenzker, L, Petrick, J.K, Schleberger, C, Jahnke, W. 登録日 2019-08-07 公開日 2020-10-07 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.189 Å) 主引用文献 T. brucei FPPS in complex with CID 112445 To Be Published
6CX8	Crystal structure of spermidine/spermine N-acetyltransferase SpeG from Vibrio cholerae in complex with manganese ions. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ISOPROPYL ALCOHOL, MANGANESE (II) ION, ... 著者 Filippova, E.V, Minasov, G, Kiryukhina, O, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2018-04-02 公開日 2018-04-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Crystal structure of spermidine/spermine N-acetyltransferase SpeG from Vibrio cholerae in complex with manganese ions. To Be Published
5GI6	Crystal Structure of Drosophila melanogaster Dopamine N-Acetyltransferase Bound to CoA and Phenylethylamine 分子名称: 2-PHENYLETHYLAMINE, COENZYME A, Dopamine N-acetyltransferase 著者 Yang, Y.C, Cheng, H.C, Lyu, P.C. 登録日 2016-06-22 公開日 2017-07-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal Structure of Drosophila melanogaster Dopamine N-Acetyltransferase Bound to CoA and Phenylethylamine To Be Published
7DXH	Cryo-EM structure of PSII intermediate Psb28-PSII complex 分子名称: (1S)-2-(ALPHA-L-ALLOPYRANOSYLOXY)-1-[(TRIDECANOYLOXY)METHYL]ETHYL PALMITATE, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 5-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-HEPTAMETHYLOCTACOSA-2,6,10,14,18,22,26-HEPTAENYL]-2,3-DIMETHYLBENZO-1,4-QUINONE, ... 著者 Sui, S.F, Shen, J.R, Han, G.Y, Xiao, Y.N, Huang, G.Q. 登録日 2021-01-18 公開日 2021-06-30 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 Structural insights into cyanobacterial photosystem II intermediates associated with Psb28 and Tsl0063. Nat.Plants, 7, 2021
5QPQ	PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000631a 分子名称: ACETATE ION, Farnesyl diphosphate synthase, SULFATE ION, ... 著者 Petrick, J.K, Nelson, E.R, Muenzker, L, Krojer, T, Douangamath, A, Brandao-Neto, J, von Delft, F, Dekker, C, Jahnke, W. 登録日 2019-03-12 公開日 2020-04-29 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library To Be Published

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