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2PZF
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Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer with delta F508
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
著者Atwell, S, Conners, K, Emtage, S, Gheyi, T, Glenn, N.R, Hendle, J, Lewis, H.A, Lu, F, Rodgers, L.A, Romero, R, Sauder, J.M, Smith, D, Tien, H, Wasserman, S.R, Zhao, X.
登録日2007-05-18
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.
Protein Eng.Des.Sel., 23, 2010
2PZG
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Minimal human CFTR first nucleotide binding domain as a monomer
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, GLYCEROL, ...
著者Atwell, S, Conners, K, Emtage, S, Gheyi, T, Glenn, N.R, Hendle, J, Lewis, H.A, Lu, F, Rodgers, L.A, Romero, R, Sauder, J.M, Smith, D, Tien, H, Wasserman, S.R, Zhao, X.
登録日2007-05-18
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.
Protein Eng.Des.Sel., 23, 2010
2PZH
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YbgC thioesterase (Hp0496) from Helicobacter pylori
分子名称: Hypothetical protein HP_0496
著者Angelini, A, Cendron, L, Goncalves, S, Zanotti, G, Terradot, L.
登録日2007-05-18
公開日2008-04-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and enzymatic characterization of HP0496, a YbgC thioesterase from Helicobacter pylori.
Proteins, 72, 2008
2PZI
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Crystal Structure of Protein kinase PknG from Mycobacterium tuberculosis in Complex with Tetrahydrobenzothiophene AX20017
分子名称: 2-[(CYCLOPROPYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE, CADMIUM ION, CHLORIDE ION, ...
著者Honnappa, S, Steinmetz, M.O.
登録日2007-05-18
公開日2007-07-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2PZJ
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Crystal structure of the Bordetella bronchiseptica enzyme WbmF in complex with NAD+
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative nucleotide sugar epimerase/ dehydratase
著者Harmer, N.J, King, J.D, Palmer, C.M, Maskell, D, Blundell, T.L.
登録日2007-05-18
公開日2007-10-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Predicting protein function from structure--the roles of short-chain dehydrogenase/reductase enzymes in Bordetella O-antigen biosynthesis.
J.Mol.Biol., 374, 2007
2PZK
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Crystal structure of the Bordetella bronchiseptica enzyme WbmG in complex with NAD
分子名称: MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative nucleotide sugar epimerase/ dehydratase
著者King, J.D, Harmer, N.J, Maskell, D.J, Blundell, T.L.
登録日2007-05-18
公開日2007-10-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Predicting protein function from structure--the roles of short-chain dehydrogenase/reductase enzymes in Bordetella O-antigen biosynthesis.
J.Mol.Biol., 374, 2007
2PZL
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Crystal structure of the Bordetella bronchiseptica enzyme WbmG in complex with NAD and UDP
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative nucleotide sugar epimerase/ dehydratase, URIDINE-5'-DIPHOSPHATE
著者King, J.D, Harmer, N.J, Maskell, D.J, Blundell, T.L.
登録日2007-05-18
公開日2007-10-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Predicting protein function from structure--the roles of short-chain dehydrogenase/reductase enzymes in Bordetella O-antigen biosynthesis.
J.Mol.Biol., 374, 2007
2PZM
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Crystal structure of the Bordetella bronchiseptica enzyme WbmG in complex with NAD and UDP
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative nucleotide sugar epimerase/ dehydratase, SULFATE ION, ...
著者Harmer, N.J, King, J.D, Palmer, C.M, Maskell, D, Blundell, T.L.
登録日2007-05-18
公開日2007-10-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Predicting protein function from structure--the roles of short-chain dehydrogenase/reductase enzymes in Bordetella O-antigen biosynthesis.
J.Mol.Biol., 374, 2007
2PZN
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The crystallographic structure of Aldose Reductase IDD393 complex confirms Leu300 as a specificity determinant
分子名称: (5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Ruiz, F, Hazemann, I, Darmanin, C, Mitschler, A, Van Zandt, M, Joachimiak, A, El-Kabbani, O, Podjarny, A.
登録日2007-05-18
公開日2008-05-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献The Crystallographic Structure of Alr2-Idd393 Complex Confirms Leu300 as a Specificity Determinant
To be Published
2PZP
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Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K526E Mutation Responsible for Crouzon Syndrome
分子名称: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Chen, H, Mohammadi, M.
登録日2007-05-18
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PZR
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Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K641R Mutation Responsible for Pfeiffer Syndrome
分子名称: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
著者Chen, H, Mohammadi, M.
登録日2007-05-18
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PZS
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Phi29 DNA polymerase complexed with primer-template DNA (post-translocation binary complex)
分子名称: 5'-d(CTAACACGTAAGCAGTC)-3', 5'-d(GACTGCTTAC)-3', DNA polymerase
著者Berman, A.J, Kamtekar, S, Goodman, J.L, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
登録日2007-05-18
公開日2007-07-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases
Embo J., 26, 2007
2PZT
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Crystal structure of Staphylococcal nuclease variant V66Q/P117G/H124L/S128A at 100 K
分子名称: PHOSPHATE ION, Thermonuclease
著者Schlessman, J.L, Abe, C, Garcia-Moreno, E.B.
登録日2007-05-18
公開日2008-05-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic study of hydration of an internal cavity in engineered proteins with buried polar or ionizable groups.
Biophys.J., 94, 2008
2PZU
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Crystal structure of Staphylococcal nuclease variant V66N/P117G/H124L/S128A at cryogenic temperature
分子名称: PHOSPHATE ION, Thermonuclease
著者Schlessman, J.L, Abe, C, Garcia-Moreno, E.B.
登録日2007-05-18
公開日2008-05-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic study of hydration of an internal cavity in engineered proteins with buried polar or ionizable groups.
Biophys.J., 94, 2008
2PZV
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BU of 2pzv by Molmil
Crystal Structure of Ketosteroid Isomerase D40N from Pseudomonas Putida (pksi) with bound Phenol
分子名称: PHENOL, Steroid Delta-isomerase
著者Pybus, B, Caaveiro, J.M.M, Petsko, G.A, Ringe, D.
登録日2007-05-18
公開日2007-06-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Testing Electrostatic complementarity in Enzyme Catalysis: Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion Hole
PLoS Biol., 4, 2006
2PZW
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Crystal structure of Staphylococcal nuclease variant V66N/P117G/H124L/S128A at room temperature
分子名称: Thermonuclease
著者Schlessman, J.L, Abe, C, Garcia-Moreno, E.B.
登録日2007-05-18
公開日2008-05-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic study of hydration of an internal cavity in engineered proteins with buried polar or ionizable groups.
Biophys.J., 94, 2008
2PZX
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BU of 2pzx by Molmil
Structure of the methuselah ectodomain with peptide inhibitor
分子名称: G-protein coupled receptor Mth
著者West Jr, A.P, Ja, W.W, Delker, S.L, Bjorkman, P.J, Benzer, S, Roberts, R.W.
登録日2007-05-18
公開日2007-08-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor.
Nat.Chem.Biol., 3, 2007
2PZY
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Structure of MK2 Complexed with Compound 76
分子名称: (4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE, MAP kinase-activated protein kinase 2, STAUROSPORINE
著者White, A, Wu, J.P, Wang, J, Abeywardane, A, Andersen, D, Emmanuel, M, Gautschi, E, Goldberg, D.R, Kashem, M.A, Lukas, S, Mao, W, Martin, L, Morwick, T, Moss, N, Pargellis, C, Patel, U.R, Patnaude, L, Peet, G.W, Skow, D, Snow, R.J, Ward, Y, Werneburg, B.
登録日2007-05-18
公開日2007-07-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The discovery of carboline analogs as potent MAPKAP-K2 inhibitors
Bioorg.Med.Chem.Lett., 17, 2007
2PZZ
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2.2 A resolution crystal structure of UPF0201 protein from Methanococcus jannaschii
分子名称: UPF0201 protein MJ1564
著者Rao, K.N, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-05-18
公開日2007-05-29
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献UPF201 archaeal specific family members reveal structural similarity to RNA-binding proteins but low likelihood for RNA-binding function.
Plos One, 3, 2008
2Q00
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Crystal structure of the P95883_SULSO protein from Sulfolobus solfataricus. NESG target SsR10.
分子名称: Orf c02003 protein
著者Vorobiev, S.M, Chen, Y, Seetharaman, J, Wang, D, Owens, L, Ma, L.-C, Cunningham, K, Fang, Y, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2007-05-18
公開日2007-05-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the P95883_SULSO protein from Sulfolobus solfataricus.
To be Published
2Q01
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Crystal structure of glucuronate isomerase from Caulobacter crescentus
分子名称: POTASSIUM ION, Uronate isomerase
著者Patskovsky, Y, Bonanno, J, Sridhar, V, Sauder, J.M, Freeman, J, Powell, A, Koss, J, Groshong, C, Gheyi, T, Wasserman, S.R, Raushel, F, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-05-18
公開日2007-05-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Crystal Structure of Glucuronate Isomerase from Caulobacter crescentus.
To be Published
2Q02
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Crystal structure of a xylose isomerase domain containing protein (stm4435) from salmonella typhimurium lt2 at 2.40 A resolution
分子名称: CHLORIDE ION, Putative cytoplasmic protein, UNKNOWN LIGAND, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2007-05-18
公開日2007-06-05
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of putative cytoplasmic protein (NP_463296.1) from Salmonella typhimurium LT2 at 2.40 A resolution
To be published
2Q03
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Crystal structure of uncharacterized protein (YP_563039.1) from Shewanella denitrificans OS217 at 1.80 A resolution
分子名称: GLYCEROL, Uncharacterized protein
著者Joint Center for Structural Genomics (JCSG)
登録日2007-05-18
公開日2007-05-29
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of uncharacterized protein (YP_563039.1) from Shewanella denitrificans OS217 at 1.80 A resolution
To be published
2Q04
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Crystal structure of acetoin utilization protein (ZP_00540088.1) from Exiguobacterium sibiricum 255-15 at 2.33 A resolution
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, Acetoin utilization protein, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2007-05-18
公開日2007-06-12
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal structure of acetoin utilization protein (ZP_00540088.1) from Exiguobacterium sibiricum 255-15 at 2.33 A resolution
To be published
2Q05
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Crystal structure of tyr/ser protein phosphatase from Vaccinia virus WR
分子名称: Dual specificity protein phosphatase
著者Osipiuk, J, Skarina, T, Kagan, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2007-05-18
公開日2007-06-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Crystal structure of tyr/ser protein phosphatase from Vaccinia virus WR.
To be Published

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