PDB: 224931 件ウェブページステータス検索Chemie searchBIRD

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2PVL	Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 分子名称: 2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE, Casein kinase II subunit alpha 著者 Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. 登録日 2007-05-09 公開日 2008-05-13 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
2PVM	Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 分子名称: 4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE, Casein kinase II subunit alpha 著者 Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. 登録日 2007-05-09 公開日 2008-05-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
2PVN	Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 分子名称: Casein kinase II subunit alpha, N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE 著者 Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. 登録日 2007-05-09 公開日 2008-05-13 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
2PVO	Crystal srtucture of the ternary complex between thioredoxin f, ferredoxin, and ferredoxin: thioredoxin reductase 分子名称: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-1, Ferredoxin-thioredoxin reductase, ... 著者 Dai, S. 登録日 2007-05-09 公開日 2007-07-10 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural snapshots along the reaction pathway of ferredoxin-thioredoxin reductase. Nature, 448, 2007
2PVP	Crystal structure of D-Alanine-D-Alanine Ligase from Helicobacter pylori 分子名称: D-alanine-D-alanine ligase 著者 Wu, D, Zhang, L, Jiang, H, Shen, X. 登録日 2007-05-10 公開日 2008-04-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Enzymatic characterization and crystal structure analysis of the D-alanine-D-alanine ligase from Helicobacter pylori. Proteins, 72, 2008
2PVQ	Crystal structure of Ochrobactrum anthropi glutathione transferase Cys10Ala mutant with glutathione bound at the H-site 分子名称: GLUTATHIONE, SULFATE ION, glutathione S-transferase 著者 Allocati, N, Federici, L, Masulli, M, Favaloro, B, Di Ilio, C. 登録日 2007-05-10 公開日 2008-01-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.803 Å) 主引用文献 Cysteine 10 is critical for the activity of Ochrobactrum anthropi glutathione transferase and its mutation to alanine causes the preferential binding of glutathione to the H-site. Proteins, 71, 2008
2PVR	Crystal structure of the catalytic subunit of protein kinase CK2 (C-terminal deletion mutant 1-335) in complex with two sulfate ions 分子名称: Casein kinase II subunit alpha, catalytic subunit, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Niefind, K, Yde, C.W, Ermakova, I, Issinger, O.-G. 登録日 2007-05-10 公開日 2007-06-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.605 Å) 主引用文献 Evolved to Be Active: Sulfate Ions Define Substrate Recognition Sites of CK2alpha and Emphasise its Exceptional Role within the CMGC Family of Eukaryotic Protein Kinases J.Mol.Biol., 370, 2007
2PVS	Structure of human pancreatic lipase related protein 2 mutant N336Q 分子名称: CALCIUM ION, Pancreatic lipase-related protein 2, SULFATE ION 著者 Spinelli, S, Eydoux, C, Carriere, F, Cambillau, C. 登録日 2007-05-10 公開日 2007-12-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation. Biochemistry, 47, 2008
2PVT	Crystal structure of a new isoform of phospholipase A2 from russells viper at 2.1 A resolution 分子名称: phospholipase A2 著者 Kumar, S, Singh, N, Sharma, S, Kaur, P, Singh, T.P. 登録日 2007-05-10 公開日 2007-05-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of a new isoform of phospholipase A2 from russells viper at 2.1 A resolution To be Published
2PVU	Crystal structures of the arginine-, lysine-, histidine-binding protein ArtJ from the thermophilic bacterium Geobacillus stearothermophilus 分子名称: ArtJ, LYSINE, SULFATE ION 著者 Vahedi-Faridi, A, Scheffel, F, Eckey, V, Saenger, W, Schneider, E. 登録日 2007-05-10 公開日 2008-01-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Crystal structures and mutational analysis of the arginine-, lysine-, histidine-binding protein ArtJ from Geobacillus stearothermophilus. Implications for interactions of ArtJ with its cognate ATP-binding cassette transporter, Art(MP)2 J.Mol.Biol., 375, 2008
2PVV	Structure of human glutamate carboxypeptidase II (GCPII) in complex with L-serine-O-sulfate 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Barinka, C, Lubkowski, J. 登録日 2007-05-10 公開日 2007-05-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II. J.Med.Chem., 50, 2007
2PVW	A high resolution structure of human glutamate carboxypeptidase II (GCPII) in complex with 2-(phosphonomethyl)pentanedioic acid (2-PMPA) 分子名称: (2S)-2-(PHOSPHONOMETHYL)PENTANEDIOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Barinka, C, Lubkowski, J. 登録日 2007-05-10 公開日 2007-05-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II. J.Med.Chem., 50, 2007
2PVX	NMR and X-ray Analysis of Structural Additivity in Metal Binding Site-Swapped Hybrids of Rubredoxin 分子名称: Rubredoxin, ZINC ION 著者 Wang, L, LeMaster, D.M, Hernandez, G, Li, H. 登録日 2007-05-10 公開日 2007-12-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.04 Å) 主引用文献 NMR and X-ray analysis of structural additivity in metal binding site-swapped hybrids of rubredoxin Bmc Struct.Biol., 7, 2007
2PVY	Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome. 分子名称: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION 著者 Chen, H, Mohammadi, M. 登録日 2007-05-10 公開日 2007-09-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007
2PVZ	Crystal structure of methylaconitate isomerase PrpF from Shewanella oneidensis 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, PrpF methylaconitate isomerase 著者 Garvey, G.S, Rayment, I.R. 登録日 2007-05-10 公開日 2007-08-21 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 The three-dimensional crystal structure of the PrpF protein of Shewanella oneidensis complexed with trans-aconitate: insights into its biological function. Protein Sci., 16, 2007
2PW0	crystal structure of trans-aconitate bound to methylaconitate isomerase PrpF from Shewanella oneidensis 分子名称: 1,2-ETHANEDIOL, PrpF methylaconitate isomerase, TRICARBALLYLIC ACID 著者 Garvey, G.S, Rayment, I.R. 登録日 2007-05-10 公開日 2007-08-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 The three-dimensional crystal structure of the PrpF protein of Shewanella oneidensis complexed with trans-aconitate: insights into its biological function. Protein Sci., 16, 2007
2PW1	Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ELDKWNSL 分子名称: 2F5 Fab fragment heavy chain, 2F5 Fab fragment light chain, peptide epitope 著者 Bryson, S, Julien, J.-P, Hynes, R.C, Pai, E.F. 登録日 2007-05-10 公開日 2007-05-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications. J.Virol., 83, 2009
2PW2	Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ELDKWKSL 分子名称: 2F5 Fab' heavy chain, 2F5 Fab' light chain, peptide epitope 著者 Bryson, S, Julien, J.-P, Hynes, R.C, Pai, E.F. 登録日 2007-05-10 公開日 2007-05-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications. J.Virol., 83, 2009
2PW3	Structure of the PDE4D-cAMP complex 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ZINC ION, cAMP-specific 3',5'-cyclic phosphodiesterase 4D 著者 Wang, H, Robinson, H, Ke, H. 登録日 2007-05-10 公開日 2007-10-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 The molecular basis for different recognition of substrates by phosphodiesterase families 4 and 10. J.Mol.Biol., 371, 2007
2PW5	Crystal Structure of Staphylococcal nuclease variant V66Y/P117G/H124L/S128A at room temperature 分子名称: Thermonuclease 著者 Schlessman, J.L, Abe, C, Garcia-Moreno, E.B. 登録日 2007-05-10 公開日 2008-04-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystallographic study of hydration of an internal cavity in engineered proteins with buried polar or ionizable groups. Biophys.J., 94, 2008
2PW6	Crystal structure of uncharacterized protein JW3007 from Escherichia coli K12 分子名称: Uncharacterized protein ygiD, ZINC ION 著者 Newton, M.G, Takagi, Y, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokayama, S, Li, Y, Chen, L, Zhu, J, Ruble, J, Liu, Z.J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-05-10 公開日 2007-06-12 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Crystal structure of uncharacterized protein JW3007 from Escherichia coli K12. To be Published
2PW7	Crystal Structure of Staphylococcal nuclease variant V66Y/P117G/H124L/S128A at 100K 分子名称: Thermonuclease 著者 Schlessman, J.L, Abe, C, Garcia-Moreno, E.B. 登録日 2007-05-10 公開日 2008-04-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystallographic study of hydration of an internal cavity in engineered proteins with buried polar or ionizable groups. Biophys.J., 94, 2008
2PW8	Crystal structure of sulfo-hirudin complexed to thrombin 分子名称: Hirudin variant-1, NICKEL (II) ION, SODIUM ION, ... 著者 Liu, C.C, Brustad, E, Liu, W, Schultz, P.G. 登録日 2007-05-10 公開日 2007-08-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin. J.Am.Chem.Soc., 129, 2007
2PW9	Crystal structure of a putative formate dehydrogenase accessory protein from Desulfotalea psychrophila 分子名称: Putative formate dehydrogenase accessory protein, SULFATE ION 著者 Bonanno, J.B, Dickey, M, Bain, K.T, Logan, C, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2007-05-10 公開日 2007-05-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of a putative formate dehydrogenase accessory protein from Desulfotalea psychrophila. To be Published
2PWA	Crystal Structure of the complex of Proteinase K with Alanine Boronic acid at 0.83A resolution 分子名称: ALANINE BORONIC ACID, CALCIUM ION, NITRATE ION, ... 著者 Jain, R, Singh, N, Perbandt, M, Betzel, C, Sharma, S, Kaur, P, Srinivasan, A, Singh, T.P. 登録日 2007-05-11 公開日 2007-05-29 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (0.83 Å) 主引用文献 Crystal structure of the complex of Proteinase K with Alanine Boronic Acid at 0.83A Resolution To be Published

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