5CWU
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![BU of 5cwu by Molmil](/molmil-images/mine/5cwu) | Crystal structure of Chaetomium thermophilum Nup188 TAIL domain | 分子名称: | GLYCEROL, Nucleoporin NUP188 | 著者 | Stuwe, T, Bley, C.J, Thierbach, K, Petrovic, S, Schilbach, S, Mayo, D.J, Perriches, T, Rundlet, E.J, Jeon, Y.E, Collins, L.N, Lin, D.H, Paduch, M, Koide, A, Lu, V, Fischer, J, Hurt, E, Koide, S, Kossiakoff, A.A, Hoelz, A. | 登録日 | 2015-07-28 | 公開日 | 2015-09-16 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Architecture of the fungal nuclear pore inner ring complex. Science, 350, 2015
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7LGV
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![BU of 7lgv by Molmil](/molmil-images/mine/7lgv) | |
7LO0
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![BU of 7lo0 by Molmil](/molmil-images/mine/7lo0) | Structure of human ASF1a in complex with a TLK2 peptide | 分子名称: | Histone chaperone ASF1A, Serine/threonine-protein kinase tousled-like 2 | 著者 | Simon, B, Calderwood, D, Turk, B.E, Boggon, T.J. | 登録日 | 2021-02-08 | 公開日 | 2022-02-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry. Nat Commun, 13, 2022
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2Y56
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![BU of 2y56 by Molmil](/molmil-images/mine/2y56) | Fragment growing induces conformational changes in acetylcholine- binding protein: A structural and thermodynamic analysis - (Compound 3) | 分子名称: | CHLORIDE ION, GLYCEROL, SOLUBLE ACETYLCHOLINE RECEPTOR, ... | 著者 | Rucktooa, P, Edink, E, deEsch, I.J.P, Sixma, T.K. | 登録日 | 2011-01-12 | 公開日 | 2011-06-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.59 Å) | 主引用文献 | Fragment Growing Induces Conformational Changes in Acetylcholine-Binding Protein: A Structural and Thermodynamic Analysis. J.Am.Chem.Soc., 133, 2011
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7RTH
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![BU of 7rth by Molmil](/molmil-images/mine/7rth) | Crystal structure of an anti-lysozyme nanobody in complex with an anti-nanobody Fab "NabFab" | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Fragment Antigen-Binding Heavy Chain, ... | 著者 | Filippova, E.V, Mukherjee, S, Bloch, J.S, Locher, K.P, Kossiakoff, A.A. | 登録日 | 2021-08-13 | 公開日 | 2021-09-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins. Proc.Natl.Acad.Sci.USA, 118, 2021
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6Z1S
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![BU of 6z1s by Molmil](/molmil-images/mine/6z1s) | Structure of Polyphenol Oxidase (mutant G292N) from Thermothelomyces thermophila | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Dimarogona, M, Nikolaivits, E, Valmas, A, Topakas, E. | 登録日 | 2020-05-14 | 公開日 | 2021-03-24 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Considerations Regarding Activity Determinants of Fungal Polyphenol Oxidases Based on Mutational and Structural Studies. Appl.Environ.Microbiol., 87, 2021
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4OGC
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![BU of 4ogc by Molmil](/molmil-images/mine/4ogc) | Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii | 分子名称: | ACETATE ION, HNH endonuclease domain protein, MAGNESIUM ION, ... | 著者 | Jiang, F, Ma, E, Lin, S, Doudna, J.A. | 登録日 | 2014-01-15 | 公開日 | 2014-02-12 | 最終更新日 | 2014-03-26 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science, 343, 2014
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3UJG
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![BU of 3ujg by Molmil](/molmil-images/mine/3ujg) | Crystal structure of SnRK2.6 in complex with HAB1 | 分子名称: | MAGNESIUM ION, Protein phosphatase 2C 16, SULFATE ION, ... | 著者 | Zhou, X.E, Soon, F.-F, Ng, L.-M, Kovach, A, Tan, M.H.E, Suino-Powell, K.M, He, Y, Xu, Y, Brunzelle, J.S, Li, J, Melcher, K, Xu, H.E. | 登録日 | 2011-11-07 | 公開日 | 2012-02-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases. Science, 335, 2012
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4OGE
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![BU of 4oge by Molmil](/molmil-images/mine/4oge) | Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii | 分子名称: | HNH endonuclease domain protein, MAGNESIUM ION, SPERMIDINE, ... | 著者 | Jiang, F, Ma, E, Lin, S, Doudna, J.A. | 登録日 | 2014-01-15 | 公開日 | 2014-02-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science, 343, 2014
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3UJK
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![BU of 3ujk by Molmil](/molmil-images/mine/3ujk) | Crystal structure of protein phosphatase ABI2 | 分子名称: | MAGNESIUM ION, Protein phosphatase 2C 77 | 著者 | Zhou, X.E, Soon, F.-F, Ng, L.-M, Kovach, A, Tan, M.H.E, Suino-Powell, K.M, He, Y, Xu, Y, Brunzelle, J.S, Li, J, Melcher, K, Xu, H.E. | 登録日 | 2011-11-07 | 公開日 | 2012-02-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases. Science, 335, 2012
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2GDM
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![BU of 2gdm by Molmil](/molmil-images/mine/2gdm) | LEGHEMOGLOBIN (OXY) | 分子名称: | LEGHEMOGLOBIN (OXY), OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Harutyunyan, E.H, Safonova, T.N, Kuranova, I.P, Popov, A.N, Teplyakov, A.V, Obmolova, G.V, Rusakov, A.A, Dodson, G.G, Wilson, J.C, Perutz, M.F. | 登録日 | 1994-09-14 | 公開日 | 1995-10-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Structure of Deoxy-and Oxy-Leghaemoglobin from Lupin J.Mol.Biol., 251, 1995
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5VHX
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![BU of 5vhx by Molmil](/molmil-images/mine/5vhx) | GluA2-1xGSG1L bound to ZK | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | 著者 | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | 登録日 | 2017-04-13 | 公開日 | 2017-05-03 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (8.3 Å) | 主引用文献 | Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes. Neuron, 94, 2017
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1MQD
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![BU of 1mqd by Molmil](/molmil-images/mine/1mqd) | X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with (S)-Des-Me-AMPA at 1.46 A resolution. Crystallization in the presence of lithium sulfate. | 分子名称: | (S)-2-AMINO-3-(3-HYDROXY-ISOXAZOL-4-YL)PROPIONIC ACID, GLYCEROL, Glutamate receptor subunit 2, ... | 著者 | Kasper, C, Lunn, M.-L, Liljefors, T, Gouaux, E, Egebjerg, J, Kastrup, J.S. | 登録日 | 2002-09-16 | 公開日 | 2003-07-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | GluR2 ligand-binding core complexes: Importance of the isoxazolol moiety and 5-substituent for the binding mode of AMPA-type agonists. FEBS Lett., 531, 2002
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2XZ6
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![BU of 2xz6 by Molmil](/molmil-images/mine/2xz6) | MTSET-modified Y53C mutant of Aplysia AChBP | 分子名称: | 2-(TRIMETHYLAMMONIUM)ETHYL THIOL, SOLUBLE ACETYLCHOLINE RECEPTOR | 著者 | Brams, M, Gay, E.A, Colon Saez, J, Guskov, A, Van Elk, R, Van Der Schors, R.C, Peigneur, S, Tytgat, J, Strelkov, S.V, Smit, A.B, Yakel, J.L, Ulens, C. | 登録日 | 2010-11-23 | 公開日 | 2010-12-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.137 Å) | 主引用文献 | Crystal Structures of a Cysteine-Modified Mutant in Loop D of Acetylcholine Binding Protein J.Biol.Chem., 286, 2011
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5VGB
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![BU of 5vgb by Molmil](/molmil-images/mine/5vgb) | Crystal structure of NmeCas9 HNH domain bound to anti-CRISPR AcrIIC1 | 分子名称: | Anti-CRISPR protein (AcrIIC1), CRISPR-associated endonuclease Cas9, GLYCEROL, ... | 著者 | Harrington, L.B, Doxzen, K.W, Ma, E, Knott, G.J, Kranzusch, P.J, Doudna, J.A. | 登録日 | 2017-04-10 | 公開日 | 2017-08-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.497 Å) | 主引用文献 | A Broad-Spectrum Inhibitor of CRISPR-Cas9. Cell, 170, 2017
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1MDN
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![BU of 1mdn by Molmil](/molmil-images/mine/1mdn) | WILD TYPE MYOGLOBIN WITH CO | 分子名称: | PROTEIN (MYOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE | 著者 | Murshudov, G.N, Krzywda, S, Brzozowski, A.M, Jaskolski, M, Scott, E.E, Klizas, S.A, Gibson, Q.H, Olson, J.S, Wilkinson, A.J. | 登録日 | 1998-08-12 | 公開日 | 1998-09-30 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Stabilizing bound O2 in myoglobin by valine68 (E11) to asparagine substitution. Biochemistry, 37, 1998
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7LXT
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![BU of 7lxt by Molmil](/molmil-images/mine/7lxt) | Structure of Plasmodium falciparum 20S proteasome with bound bortezomib | 分子名称: | 20S proteasome alpha-1 subunit, 20S proteasome alpha-2 subunit, 20S proteasome alpha-3 subunit, ... | 著者 | Morton, C.J, Metcalfe, R.D, Liu, B, Xie, S.C, Hanssen, E, Leis, A.P, Tilley, L, Griffin, M.D.W. | 登録日 | 2021-03-05 | 公開日 | 2021-09-22 | 最終更新日 | 2022-04-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome. Proc.Natl.Acad.Sci.USA, 118, 2021
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7LXU
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![BU of 7lxu by Molmil](/molmil-images/mine/7lxu) | Structure of Plasmodium falciparum 20S proteasome with bound MPI-5 | 分子名称: | 20S proteasome alpha-1 subunit, 20S proteasome alpha-2 subunit, 20S proteasome alpha-3 subunit, ... | 著者 | Metcalfe, R.D, Morton, C.J, Xie, S.C, Liu, B, Hanssen, E, Leis, A.P, Tilley, L, Griffin, M.D.W. | 登録日 | 2021-03-05 | 公開日 | 2021-09-22 | 最終更新日 | 2022-04-13 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome. Proc.Natl.Acad.Sci.USA, 118, 2021
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1W1O
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![BU of 1w1o by Molmil](/molmil-images/mine/1w1o) | Native Cytokinin Dehydrogenase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYTOKININ DEHYDROGENASE 1, ... | 著者 | Malito, E, Mattevi, A. | 登録日 | 2004-06-23 | 公開日 | 2004-08-26 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structures of Michaelis and Product Complexes of Plant Cytokinin Dehydrogenase: Implications for Flavoenzyme Catalysis J.Mol.Biol., 341, 2004
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1M5B
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![BU of 1m5b by Molmil](/molmil-images/mine/1m5b) | X-RAY STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH 2-Me-Tet-AMPA AT 1.85 A RESOLUTION. | 分子名称: | (S)-2-AMINO-3-[3-HYDROXY-5-(2-METHYL-2H-TETRAZOL-5-YL)ISOXAZOL-4-YL]PROPIONIC ACID, Glutamate receptor 2, ZINC ION | 著者 | Hogner, A, Kastrup, J.S, Jin, R, Liljefors, T, Mayer, M.L, Egebjerg, J, Larsen, I.K, Gouaux, E. | 登録日 | 2002-07-09 | 公開日 | 2002-09-18 | 最終更新日 | 2017-08-16 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Basis for AMPA Receptor Activation and Ligand Selectivity:
Crystal Structures of Five Agonist Complexes with the GluR2 Ligand-binding
Core J.Mol.Biol., 322, 2002
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7LXV
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![BU of 7lxv by Molmil](/molmil-images/mine/7lxv) | Structure of human 20S proteasome with bound MPI-5 | 分子名称: | N-[(1R)-2-([1,1'-biphenyl]-4-yl)-1-boronoethyl]-1-methyl-L-prolinamide, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... | 著者 | Metcalfe, R.D, Morton, C.J, Liu, B, Xie, S.C, Hanssen, E, Leis, A.P, Tilley, L, Griffin, M.D.W. | 登録日 | 2021-03-05 | 公開日 | 2021-09-22 | 最終更新日 | 2022-04-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome. Proc.Natl.Acad.Sci.USA, 118, 2021
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7QJQ
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![BU of 7qjq by Molmil](/molmil-images/mine/7qjq) | Crystal structure of a cutinase enzyme from Thermobifida fusca NTU22 (702) | 分子名称: | Acetylxylan esterase, DI(HYDROXYETHYL)ETHER | 著者 | Zahn, M, Gill, R.S, Avilan, L, Beckham, G.T, McGeehan, J.E. | 登録日 | 2021-12-17 | 公開日 | 2022-12-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Sourcing thermotolerant poly(ethylene terephthalate) hydrolase scaffolds from natural diversity Nat Commun, 13, 2022
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5VSU
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![BU of 5vsu by Molmil](/molmil-images/mine/5vsu) | Structure of yeast U6 snRNP with 2'-phosphate terminated U6 RNA | 分子名称: | Saccharomyces cerevisiae strain T8 chromosome XII sequence, U4/U6 snRNA-associated-splicing factor PRP24, U6 snRNA-associated Sm-like protein LSm2, ... | 著者 | Montemayor, E.J. | 登録日 | 2017-05-12 | 公開日 | 2018-05-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA. Nat Commun, 9, 2018
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7QJN
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![BU of 7qjn by Molmil](/molmil-images/mine/7qjn) | Crystal structure of an alpha/beta-hydrolase enzyme from Candidatus Kryptobacter tengchongensis (306) | 分子名称: | Dienelactone hydrolase, PHOSPHATE ION | 著者 | Zahn, M, Gill, R.S, Erickson, E, Beckham, G.T, McGeehan, J.E. | 登録日 | 2021-12-17 | 公開日 | 2022-12-28 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.885 Å) | 主引用文献 | Sourcing thermotolerant poly(ethylene terephthalate) hydrolase scaffolds from natural diversity Nat Commun, 13, 2022
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5VD3
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![BU of 5vd3 by Molmil](/molmil-images/mine/5vd3) | |