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7R6Q
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BU of 7r6q by Molmil
State E2 nucleolar 60S ribosome biogenesis intermediate - Foot region model
分子名称: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
著者Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
登録日2021-06-23
公開日2022-11-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7W6S
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BU of 7w6s by Molmil
CryoEM structure of human KChIP2-Kv4.3 complex
分子名称: Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 2
著者Ma, D.M, Guo, J.T.
登録日2021-12-02
公開日2022-11-02
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for the gating modulation of Kv4.3 by auxiliary subunits.
Cell Res., 32, 2022
7W6N
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CryoEM structure of human KChIP1-Kv4.3 complex
分子名称: Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 1
著者Ma, D.M, Guo, J.T.
登録日2021-12-02
公開日2022-11-02
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for the gating modulation of Kv4.3 by auxiliary subunits.
Cell Res., 32, 2022
7W6T
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BU of 7w6t by Molmil
CryoEM structure of human KChIP1-Kv4.3-DPP6 complex
分子名称: Dipeptidyl aminopeptidase-like protein 6, Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 1
著者Ma, D.M, Guo, J.T.
登録日2021-12-02
公開日2022-11-02
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Structural basis for the gating modulation of Kv4.3 by auxiliary subunits.
Cell Res., 32, 2022
6HMX
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BU of 6hmx by Molmil
RIP2 Kinase Catalytic Domain complex with N(4,5dimethyl1Hpyrazol3yl)7methoxy6(2methylpropane2sulfonyl)quinolin4amine
分子名称: 6-~{tert}-butylsulfonyl-~{N}-(3,4-dimethyl-1~{H}-pyrazol-5-yl)-7-methoxy-quinolin-4-amine, Receptor-interacting serine/threonine-protein kinase 2
著者Convery, M.A, Haile, P.A.
登録日2018-09-13
公開日2018-11-07
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel.
ACS Med Chem Lett, 9, 2018
5FJJ
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BU of 5fjj by Molmil
Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. Family GH3 beta-D-glucosidases
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-GLUCOSIDASE, ...
著者Agirre, J, Ariza, A, Offen, W.A, Turkenburg, J.P, Roberts, S.M, McNicholas, S, Harris, P.V, McBrayer, B, Dohnalek, J, Cowtan, K.D, Davies, G.J, Wilson, K.S.
登録日2015-10-09
公開日2016-02-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Three-Dimensional Structures of Two Heavily N-Glycosylated Aspergillus Sp. Family Gh3 Beta-D-Glucosidases
Acta Crystallogr.,Sect.D, 72, 2016
5G0Q
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beta-glucuronidase with an activity-based probe (N-alkyl cyclophellitol aziridine) bound
分子名称: (1R,2S,3R,4S,5S,6R)-7-(8-AZIDOOCTYL)-3,4,5-TRIHYDROXY-, BETA-GLUCURONIDASE, GLYCEROL
著者Jin, Y, Wu, L, Jiang, J.B, Overkleeft, H.S, Davies, G.J.
登録日2016-03-22
公開日2017-04-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Activity-based probes for functional interrogation of retaining beta-glucuronidases.
Nat. Chem. Biol., 13, 2017
2H96
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Discovery of Potent, Highly Selective, and Orally Bioavailable Pyridine Carboxamide C-jun NH2-terminal Kinase Inhibitors
分子名称: 5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE, C-jun-amino-terminal kinase-interacting protein 1, GLYCEROL, ...
著者Abad-Zapatero, C.
登録日2006-06-09
公開日2006-07-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Discovery of potent, highly selective, and orally bioavailable pyridine carboxamide c-Jun NH2-terminal kinase inhibitors.
J.Med.Chem., 49, 2006
5FJI
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BU of 5fji by Molmil
Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. Family GH3 beta-D-glucosidases
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-GLUCOSIDASE, ...
著者Agirre, J, Ariza, A, Offen, W.A, Turkenburg, J.P, Roberts, S.M, McNicholas, S, Harris, P.V, McBrayer, B, Dohnalek, J, Cowtan, K.D, Davies, G.J, Wilson, K.S.
登録日2015-10-09
公開日2016-02-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Three-Dimensional Structures of Two Heavily N-Glycosylated Aspergillus Sp. Family Gh3 Beta-D-Glucosidases
Acta Crystallogr.,Sect.D, 72, 2016
5ECP
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BU of 5ecp by Molmil
Crystal Structure of FIN219-FIP1 complex with JA, MET and ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE, Glutathione S-transferase U20, ...
著者Chen, C.Y, Cheng, Y.S.
登録日2015-10-20
公開日2016-11-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.25001574 Å)
主引用文献Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5ECR
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BU of 5ecr by Molmil
Crystal Structure of FIN219-FIP1 complex with JA, VAL and Mg
分子名称: GLUTATHIONE, Glutathione S-transferase U20, Jasmonic acid-amido synthetase JAR1, ...
著者Chen, C.Y, Cheng, Y.S.
登録日2015-10-20
公開日2016-11-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7A09
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BU of 7a09 by Molmil
Structure of a human ABCE1-bound 43S pre-initiation complex - State III
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-08-07
公開日2020-10-14
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
5ECM
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BU of 5ecm by Molmil
Crystal Structure of FIN219-FIP1 complex with JA and Leu
分子名称: GLUTATHIONE, Glutathione S-transferase U20, Jasmonic acid-amido synthetase JAR1, ...
著者Chen, C.Y, Cheng, Y.S.
登録日2015-10-20
公開日2016-11-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5ECO
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BU of 5eco by Molmil
Crystal Structure of FIN219-FIP1 complex with JA, Leu and Mg
分子名称: GLUTATHIONE, Glutathione S-transferase U20, Jasmonic acid-amido synthetase JAR1, ...
著者Chen, C.Y, Cheng, Y.S.
登録日2015-10-20
公開日2016-11-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5ECH
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BU of 5ech by Molmil
Crystal Structure of FIN219-FIP1 complex with JA and ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE, Glutathione S-transferase U20, ...
著者Chen, C.Y, Cheng, Y.S.
登録日2015-10-20
公開日2016-11-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6KOR
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BU of 6kor by Molmil
Crystal structure of the RRM domain of SYNCRIP
分子名称: Heterogeneous nuclear ribonucleoprotein Q
著者Chen, Y, Chan, J, Chen, W, Jobichen, C.
登録日2019-08-12
公開日2020-01-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.602 Å)
主引用文献SYNCRIP, a new player in pri-let-7a processing.
Rna, 26, 2020
8DWD
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BU of 8dwd by Molmil
Adenine glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired with an AP site generated by the enzyme acting on purine
分子名称: ACETATE ION, Adenine DNA glycosylase, CALCIUM ION, ...
著者Russelburg, L.P, Demir, M, David, S.S, Horvath, M.P.
登録日2022-08-01
公開日2023-08-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY
To Be Published
6AC5
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BU of 6ac5 by Molmil
Crystal structure of RIPK1 death domain GlcNAcylated by EPEC effector NleB
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-interacting serine/threonine-protein kinase 1, SULFATE ION
著者Ding, J, Shao, F.
登録日2018-07-25
公開日2019-05-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.
Mol.Cell, 74, 2019
6B43
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BU of 6b43 by Molmil
CryoEM structure and atomic model of the Kaposi's sarcoma-associated herpesvirus capsid
分子名称: Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ...
著者Dai, X.H, Gong, D.Y, Sun, R, Zhou, Z.H.
登録日2017-09-25
公開日2017-11-08
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure and mutagenesis reveal essential capsid protein interactions for KSHV replication.
Nature, 553, 2018
2MWN
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BU of 2mwn by Molmil
Talin-F3 / RIAM N-terminal Peptide complex
分子名称: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, Talin-1
著者Yang, J, Zhu, L, Zhang, H, Hirbawi, J, Fukuda, K, Dwivedi, P, Liu, J, Byzova, T, Plow, E.F, Wu, J, Qin, J.
登録日2014-11-13
公開日2014-12-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion.
Nat Commun, 5, 2014
2MWI
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BU of 2mwi by Molmil
The structure of the carboxy-terminal domain of DNTTIP1
分子名称: Deoxynucleotidyltransferase terminal-interacting protein 1
著者Schwabe, J.W.R, Muskett, F.W, Itoh, T.
登録日2014-11-11
公開日2015-02-18
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting.
Nucleic Acids Res., 43, 2015
2NO3
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BU of 2no3 by Molmil
Novel 4-anilinopyrimidines as potent JNK1 Inhibitors
分子名称: 2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE, C-JUN-AMINO-TERMINAL KINASE-INTERACTING protein 1, Mitogen-activated protein kinase 8, ...
著者Abad-Zapatero, C.
登録日2006-10-24
公開日2007-04-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies.
Bioorg.Med.Chem.Lett., 17, 2007
4D6K
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BU of 4d6k by Molmil
Structure of DNTTIP1 dimerisation domain.
分子名称: DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1
著者Itoh, T, Fairall, L, Schwabe, J.W.R.
登録日2014-11-11
公開日2015-02-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Functional Characterization of a Cell Cycle Associated Hdac1/2 Complex Reveals the Structural Basis for Complex Assembly and Nucleosome Targeting.
Nucleic Acids Res., 43, 2015
2OEX
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BU of 2oex by Molmil
Structure of ALIX/AIP1 V Domain
分子名称: Programmed cell death 6-interacting protein
著者Fisher, R.D, Zhai, Q, Robinson, H, Hill, C.P.
登録日2007-01-01
公開日2007-03-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structural and Biochemical Studies of ALIX/AIP1 and Its Role in Retrovirus Budding
Cell(Cambridge,Mass.), 128, 2007
5ECI
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BU of 5eci by Molmil
Crystal Structure of FIN219-FIP1 complex with JA, ATP and Mg
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE, Glutathione S-transferase U20, ...
著者Chen, C.Y, Cheng, Y.S.
登録日2015-10-20
公開日2016-11-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

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