2WHQ
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![BU of 2whq by Molmil](/molmil-images/mine/2whq) | Crystal structure of acetylcholinesterase, phosphonylated by sarin (aged) in complex with HI-6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(AMINOCARBONYL)-1-[({2-[(E)-(HYDROXYIMINO)METHYL]PYRIDINIUM-1-YL}METHOXY)METHYL]PYRIDINIUM, ACETYLCHOLINESTERASE, ... | 著者 | Ekstrom, F, Hornberg, A, Artursson, E, Hammarstrom, L.G, Schneider, G, Pang, Y.P. | 登録日 | 2009-05-06 | 公開日 | 2009-06-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure of Hi-6Sarin-Acetylcholinesterase Determined by X-Ray Crystallography and Molecular Dynamics Simulation: Reactivator Mechanism and Design. Plos One, 4, 2009
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2WU3
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![BU of 2wu3 by Molmil](/molmil-images/mine/2wu3) | CRYSTAL STRUCTURE OF MOUSE ACETYLCHOLINESTERASE IN COMPLEX WITH FENAMIPHOS AND HI-6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(AMINOCARBONYL)-1-[({2-[(E)-(HYDROXYIMINO)METHYL]PYRIDINIUM-1-YL}METHOXY)METHYL]PYRIDINIUM, ACETYLCHOLINESTERASE, ... | 著者 | Hornberg, A, Artursson, E, Warme, R, Pang, Y.-P, Ekstrom, F. | 登録日 | 2009-09-28 | 公開日 | 2009-10-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structures of Oxime-Bound Fenamiphos-Acetylcholinesterases: Reactivation Involving Flipping of the His447 Ring to Form a Reactive Glu334-His447-Oxime Triad. Biochem.Pharm., 79, 2010
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2WLS
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![BU of 2wls by Molmil](/molmil-images/mine/2wls) | Crystal structure of Mus musculus Acetylcholinesterase in complex with AMTS13 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Pang, Y.P, Ekstrom, F, Polsinelli, G.A, Gao, Y, Rana, S, Hua, D.H, Andersson, B, Andersson, P.O, Peng, L, Singh, S.K, Mishra, R.K, Zhu, K.Y, Fallon, A.M, Ragsdale, D.W, Brimijoin, S. | 登録日 | 2009-06-25 | 公開日 | 2009-09-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Selective and Irreversible Inhibitors of Mosquito Acetylcholinesterases for Controlling Malaria and Other Mosquito-Borne Diseases. Plos One, 4, 2009
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3ODY
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![BU of 3ody by Molmil](/molmil-images/mine/3ody) | Crystal structure of p38alpha Y323Q active mutant | 分子名称: | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | 著者 | Livnah, O, Tzarum, N. | 登録日 | 2010-08-12 | 公開日 | 2011-01-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Active mutants of the TCR-mediated p38alpha alternative activation site show changes in the phosphorylation lip and DEF site formation. J.Mol.Biol., 405, 2011
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2WZA
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3OF5
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![BU of 3of5 by Molmil](/molmil-images/mine/3of5) | Crystal Structure of a Dethiobiotin Synthetase from Francisella tularensis subsp. tularensis SCHU S4 | 分子名称: | ACETATE ION, Dethiobiotin synthetase, SODIUM ION | 著者 | Brunzelle, J.S, Skarina, T, Gordon, E, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-08-13 | 公開日 | 2011-02-02 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Crystal Structure of a Dethiobiotin Synthetase from Francisella tularensis subsp. tularensis SCHU S4 TO BE PUBLISHED
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6FHL
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![BU of 6fhl by Molmil](/molmil-images/mine/6fhl) | Cryo-EM structure of F-actin in complex with ADP-Pi | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Merino, F, Pospich, S, Funk, J, Wagner, T, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S. | 登録日 | 2018-01-15 | 公開日 | 2018-06-13 | 最終更新日 | 2018-08-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM. Nat. Struct. Mol. Biol., 25, 2018
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3OSU
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![BU of 3osu by Molmil](/molmil-images/mine/3osu) | Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, FabG, from Staphylococcus aureus | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] reductase, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | 著者 | Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Edwards, A, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-09-09 | 公開日 | 2010-09-29 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, FabG, from Staphylococcus aureus To be Published
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6FYH
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![BU of 6fyh by Molmil](/molmil-images/mine/6fyh) | Disulfide between ubiquitin G76C and the E3 HECT ligase Huwe1 | 分子名称: | E3 ubiquitin-protein ligase HUWE1, Polyubiquitin-B, SULFATE ION, ... | 著者 | Jaeckl, M, Hartmann, M.D, Wiesner, S. | 登録日 | 2018-03-12 | 公開日 | 2018-07-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.906 Å) | 主引用文献 | beta-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation. J. Mol. Biol., 430, 2018
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3OJC
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![BU of 3ojc by Molmil](/molmil-images/mine/3ojc) | Crystal structure of a putative Asp/Glu Racemase from Yersinia pestis | 分子名称: | CALCIUM ION, HEXANE-1,6-DIOL, Putative aspartate/glutamate racemase | 著者 | Anderson, S.M, Wawrzak, Z, Kudritska, M, Kwon, K, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-08-21 | 公開日 | 2010-09-15 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of a putative Asp/Glu Racemase from Yersinia pestis To be Published
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2WK6
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![BU of 2wk6 by Molmil](/molmil-images/mine/2wk6) | Structural features of native human thymidine phosphorylase and in complex with 5-iodouracil | 分子名称: | 5-IODOURACIL, THYMIDINE PHOSPHORYLASE | 著者 | Mitsiki, E, Papageorgiou, A.C, Iyer, S, Thiyagarajan, N, Prior, S.H, Sleep, D, Finnis, C, Acharya, K.R. | 登録日 | 2009-06-05 | 公開日 | 2009-07-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures of Native Human Thymidine Phosphorylase and in Complex with 5-Iodouracil. Biochem.Biophys.Res.Commun., 386, 2009
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2WL0
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![BU of 2wl0 by Molmil](/molmil-images/mine/2wl0) | HIV-1 Protease Inhibitors Containing a Tertiary Alcohol in the Transition-State Mimic with Improved Cell-Based Antiviral Activity | 分子名称: | METHYL [(1S)-1-({2-[(3S)-3-BENZYL-3-HYDROXY-4-{[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]AMINO}-4-OXOBUTYL]-2-(4-PYRIDIN-2-YLBENZYL)HYDRAZINO}CARBONYL)-2,2-DIMETHYLPROPYL]CARBAMATE, PROTEASE | 著者 | Mahalingam, A.K, Axelsson, L, Ekegren, J.K, Wannberg, J, Kihlstrom, J, Wallberg, H, Samuelsson, B, Larhed, M, Hallberg, A, Unge, T. | 登録日 | 2009-06-19 | 公開日 | 2009-12-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | HIV-1 Protease Inhibitors with a Transition-State Mimic Comprising a Tertiary Alcohol: Improved Antiviral Activity in Cells. J.Med.Chem., 53, 2010
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2VHY
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2VAJ
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![BU of 2vaj by Molmil](/molmil-images/mine/2vaj) | Crystal structure of NCAM2 Ig1 (I4122 cell unit) | 分子名称: | NEURAL CELL ADHESION MOLECULE 2 | 著者 | Kulahin, N, Rasmussen, K.K, Kristensen, O, Kastrup, J.S, Navarro-Poulsen, J.-C, Berezin, V, Bock, E, Walmod, P.S, Gajhede, M. | 登録日 | 2007-08-31 | 公開日 | 2008-08-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | 主引用文献 | Crystal Structure of the Ig1 Domain of the Neural Cell Adhesion Molecule Ncam2 Displays Domain Swapping. J.Mol.Biol., 382, 2008
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6FV7
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![BU of 6fv7 by Molmil](/molmil-images/mine/6fv7) | Dimer structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state | 分子名称: | Aq128 | 著者 | Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H. | 登録日 | 2018-03-01 | 公開日 | 2019-03-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Dimer structure of Aq128 in the outward-facing state To Be Published
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2WCT
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![BU of 2wct by Molmil](/molmil-images/mine/2wct) | human SARS coronavirus unique domain (triclinic form) | 分子名称: | NON-STRUCTURAL PROTEIN 3 | 著者 | Tan, J, Vonrhein, C, Smart, O.S, Bricogne, G, Bollati, M, Hansen, G, Mesters, J.R, Hilgenfeld, R. | 登録日 | 2009-03-16 | 公開日 | 2009-05-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | The Sars-Unique Domain (Sud) of Sars Coronavirus Contains Two Macrodomains that Bind G-Quadruplexes. Plos Pathog., 5, 2009
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6G1K
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![BU of 6g1k by Molmil](/molmil-images/mine/6g1k) | Electron cryo-microscopy structure of the canonical TRPC4 ion channel | 分子名称: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily c member 4a | 著者 | Vinayagam, D, Mager, T, Apelbaum, A, Bothe, A, Merino, F, Hofnagel, O, Gatsogiannis, C, Raunser, S. | 登録日 | 2018-03-21 | 公開日 | 2018-05-02 | 最終更新日 | 2018-08-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Electron cryo-microscopy structure of the canonical TRPC4 ion channel. Elife, 7, 2018
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2WHP
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![BU of 2whp by Molmil](/molmil-images/mine/2whp) | Crystal structure of acetylcholinesterase, phosphonylated by sarin and in complex with HI-6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(AMINOCARBONYL)-1-[({2-[(E)-(HYDROXYIMINO)METHYL]PYRIDINIUM-1-YL}METHOXY)METHYL]PYRIDINIUM, ACETYLCHOLINESTERASE, ... | 著者 | Ekstrom, F, Hornberg, A, Artursson, E, Hammarstrom, L.G, Schneider, G, Pang, Y.P. | 登録日 | 2009-05-06 | 公開日 | 2009-06-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of Hi-6Sarin-Acetylcholinesterase Determined by X-Ray Crystallography and Molecular Dynamics Simulation: Reactivator Mechanism and Design. Plos One, 4, 2009
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2WLQ
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![BU of 2wlq by Molmil](/molmil-images/mine/2wlq) | Nucleophile-disabled Lam16A mutant holds laminariheptaose (L7) in a cyclical conformation | 分子名称: | PUTATIVE LAMINARINASE, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose | 著者 | Vasur, J, Kawai, R, Andersson, E, Widmalm, G, Jonsson, K.H, Hansson, H, Engstrom, A, Igarashi, K, Sandgren, M, Samejima, M, Stahlberg, J. | 登録日 | 2009-06-24 | 公開日 | 2010-01-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Synthesis of Cyclic Beta-Glucan Using Laminarinase 16A Glycosynthase Mutant from the Basidiomycete Phanerochaete Chrysosporium. J.Am.Chem.Soc., 132, 2010
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2WKZ
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![BU of 2wkz by Molmil](/molmil-images/mine/2wkz) | HIV-1 Protease Inhibitors Containing a Tertiary Alcohol in the Transition-State Mimic with Improved Cell-Based Antiviral Activity | 分子名称: | METHYL [(1S)-1-({2-[(3S)-3-BENZYL-3-HYDROXY-4-{[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]AMINO}-4-OXOBUTYL]-2-(4-PYRIDIN-2-YLBENZYL)HYDRAZINO}CARBONYL)-2,2-DIMETHYLPROPYL]CARBAMATE, PROTEASE | 著者 | Mahalingam, A.K, Axelsson, L, Ekegren, J.K, Wannberg, J, Kihlstrom, J, Wallberg, H, Samuelsson, B, Larhed, M, Hallberg, A, Unge, T. | 登録日 | 2009-06-19 | 公開日 | 2009-12-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | HIV-1 Protease Inhibitors with a Transition-State Mimic Comprising a Tertiary Alcohol: Improved Antiviral Activity in Cells. J.Med.Chem., 53, 2010
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3MXC
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![BU of 3mxc by Molmil](/molmil-images/mine/3mxc) | |
3MXY
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3MVM
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![BU of 3mvm by Molmil](/molmil-images/mine/3mvm) | P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7V | 分子名称: | 4-{[5-(isoxazol-3-ylcarbamoyl)-2-methylphenyl]amino}-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide, Mitogen-activated protein kinase 14 | 著者 | Sack, J.S. | 登録日 | 2010-05-04 | 公開日 | 2010-10-13 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of 4-(5-(Cyclopropylcarbamoyl)-2-Methylphenylamino)-5-Methyl-Npropylpyrrolo[1,2-F][1,2,4] Triazine-6-Carboxamide (Bms-582949), a Clinical P38? Map Kinase Inhibitor for the Treatment of Inflammatory Diseases J.Med.Chem., 53, 2010
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2W52
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![BU of 2w52 by Molmil](/molmil-images/mine/2w52) | 2 beta-glucans (6-O-glucosyl-laminaritriose) in both donor and acceptor sites of GH16 Laminarinase 16A from Phanerochaete chrysosporium. | 分子名称: | PUTATIVE LAMINARINASE, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose, ... | 著者 | Vasur, J, Kawai, R, Andersson, E, Igarashi, K, Sandgren, M, Samejima, M, Stahlberg, J. | 登録日 | 2008-12-03 | 公開日 | 2009-07-21 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | X-Ray Crystal Structures of Phanerochaete Chrysosporium Laminarinase 16A in Complex with Products from Lichenin and Laminarin Hydrolysis FEBS J., 276, 2009
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3N8M
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![BU of 3n8m by Molmil](/molmil-images/mine/3n8m) | |