4Y2C
 
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6Z11
 | | Structure of Mycobacterium smegmatis HelD protein in complex with RNA polymerase core - State III, primary channel dis-engaged and active site interfering | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Kouba, T, Koval, T, Krasny, L, Dohnalek, J. | | 登録日 | 2020-05-11 | | 公開日 | 2020-11-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | | 主引用文献 | HelD, a helicase-like protein from gram-positive bacteria
in complex with RNA polymerase
To Be Published
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6L6V
 | | SPO1 Gp44 N-terminal region (1-55) | | 分子名称: | E3 protein | | 著者 | Liu, B, Wang, Z. | | 登録日 | 2019-10-29 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Bacteriophage DNA Mimic Protein Employs a Non-specific Strategy to Inhibit the Bacterial RNA Polymerase.
Front Microbiol, 12, 2021
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6PMI
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1FQZ
 | | NMR VALIDATED MODEL OF DOMAIN IIID OF HEPATITIS C VIRUS INTERNAL RIBOSOME ENTRY SITE | | 分子名称: | HEPATITIS C VIRUS IRES DOMAIN IIID | | 著者 | Klinck, R, Westhof, E, Walker, S, Afshar, M, Collier, A, Aboul-ela, F. | | 登録日 | 2000-09-07 | | 公開日 | 2001-01-17 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A potential RNA drug target in the hepatitis C virus internal ribosomal entry site.
RNA, 6, 2000
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4IQJ
 | | Structure of PolIIIalpha-Tauc-DNA complex suggests an atomic model of the replisome | | 分子名称: | DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*GP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*CP*G)-3'), DNA (5'-D(P*CP*GP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*A)-3'), DNA (5'-D(P*CP*GP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DOC))-3'), ... | | 著者 | Liu, B, Lin, J, Steitz, T. | | 登録日 | 2013-01-11 | | 公開日 | 2013-03-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure of PolIIIalpha-Tauc-DNA complex suggests an atomic model of the replisome
Structure, 21, 2013
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6YI2
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4IQZ
 | | The crystal structure of a large insert in RNA polymerase (RpoC) subunit from E. coli | | 分子名称: | DNA-directed RNA polymerase subunit beta', IODIDE ION, SODIUM ION | | 著者 | Bhandari, V, Sugiman-Marangos, S.N, Naushad, H.S, Gupta, R.S, Junop, M.S. | | 登録日 | 2013-01-14 | | 公開日 | 2013-02-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The crystal structure of a large insert in RNA polymerase (RpoC) subunit from E. coli
To be Published
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8BYQ
 | | RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W) | | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | 著者 | Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. | | 登録日 | 2022-12-14 | | 公開日 | 2023-05-03 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
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8BZ1
 | | RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W) | | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ... | | 著者 | Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. | | 登録日 | 2022-12-14 | | 公開日 | 2023-05-03 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
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7NKX
 | | RNA polymerase II-Spt4/5-nucleosome-Chd1 structure | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin elongation factor SPT4, ... | | 著者 | Farnung, L, Ochmann, M, Engeholm, M, Cramer, P. | | 登録日 | 2021-02-19 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of nucleosome transcription mediated by Chd1 and FACT.
Nat.Struct.Mol.Biol., 28, 2021
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8BVW
 | | RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W) | | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | 著者 | Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. | | 登録日 | 2022-12-20 | | 公開日 | 2023-05-03 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
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2E2J
 | | RNA polymerase II elongation complex in 5 mM Mg+2 with GMPCPP | | 分子名称: | 27-MER DNA template strand, 5'-D(P*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*A)-3', 5'-R(P*AP*UP*CP*GP*AP*GP*AP*GP*G)-3', ... | | 著者 | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | | 登録日 | 2006-11-14 | | 公開日 | 2006-12-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
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2E2H
 | | RNA polymerase II elongation complex at 5 mM Mg2+ with GTP | | 分子名称: | 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... | | 著者 | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | | 登録日 | 2006-11-14 | | 公開日 | 2006-12-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.95 Å) | | 主引用文献 | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
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2E2I
 | | RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dGTP | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', ... | | 著者 | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | | 登録日 | 2006-11-14 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | | 主引用文献 | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
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3S1M
 | | RNA Polymerase II Initiation Complex with a 5-nt RNA (variant 1) | | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*GP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | | 登録日 | 2011-05-15 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | | 主引用文献 | Initiation complex structure and promoter proofreading.
Science, 333, 2011
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3RZD
 | | RNA Polymerase II Initiation Complex with a 5-nt RNA | | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | | 登録日 | 2011-05-11 | | 公開日 | 2011-08-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Initiation complex structure and promoter proofreading.
Science, 333, 2011
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3RZO
 | | RNA Polymerase II Initiation Complex with a 4-nt RNA | | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | | 登録日 | 2011-05-12 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Initiation complex structure and promoter proofreading.
Science, 333, 2011
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3S1R
 | | RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with GTP | | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | | 登録日 | 2011-05-16 | | 公開日 | 2011-08-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Initiation complex structure and promoter proofreading.
Science, 333, 2011
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3S16
 | | RNA Polymerase II Initiation Complex with an 8-nt RNA | | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | | 登録日 | 2011-05-14 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.241 Å) | | 主引用文献 | Initiation complex structure and promoter proofreading.
Science, 333, 2011
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3S14
 | | RNA Polymerase II Initiation Complex with a 6-nt RNA | | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | | 登録日 | 2011-05-14 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Initiation complex structure and promoter proofreading.
Science, 333, 2011
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3S1N
 | | RNA Polymerase II Initiation Complex with a 5-nt RNA (variant 2) | | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*GP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | | 登録日 | 2011-05-15 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Initiation complex structure and promoter proofreading.
Science, 333, 2011
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3S2D
 | | RNA Polymerase II Initiation Complex with a 5-nt RNA containing a 5Br-U | | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*AP*CP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | | 登録日 | 2011-05-16 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Initiation complex structure and promoter proofreading.
Science, 333, 2011
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3S1Q
 | | RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | | 登録日 | 2011-05-16 | | 公開日 | 2011-08-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Initiation complex structure and promoter proofreading.
Science, 333, 2011
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3S15
 | | RNA Polymerase II Initiation Complex with a 7-nt RNA | | 分子名称: | DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | | 著者 | Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D. | | 登録日 | 2011-05-14 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Initiation complex structure and promoter proofreading.
Science, 333, 2011
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