PDB: 468 件ウェブページステータス検索Chemie searchBIRD

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1FKH	DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS, AND THE X-RAY CRYSTAL STRUCTURES OF THEIR COMPLEXES WITH FKBP12 分子名称: 1-CYCLOHEXYL-3-PHENYL-1-PROPYL-1-(3,3-DIMETHYL-1,2-DIOXYPENTYL)-2-PIPERIDINE CARBOXYLATE, FK506 BINDING PROTEIN 著者 Holt, D.A, Luengo, J.I, Yamashita, D.S, Oh, H.-J, Konialian, A.L, Yen, H.-K, Rozamus, L.W, Brandt, M, Bossard, M.J, Levy, M.A, Eggleston, D.S, Stout, T.J, Liang, J, Schultz, L.W, Clardy, J. 登録日 1993-08-05 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS AND THE X-RAY CRYSTAL-STRUCTURES OF THEIR COMPLEXES WITH FKBP12. J.Am.Chem.Soc., 115, 1993
1FKG	DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS, AND THE X-RAY CRYSTAL STRUCTURES OF THEIR COMPLEXES WITH FKBP12 分子名称: 1,3-DIPHENYL-1-PROPYL-1-(3,3-DIMETHYL-1,2-DIOXYPENTYL)-2-PIPERIDINE CARBOXYLATE, FK506 BINDING PROTEIN 著者 Holt, D.A, Luengo, J.I, Yamashita, D.S, Oh, H.-J, Konialian, A.L, Yen, H.-K, Rozamus, L.W, Brandt, M, Bossard, M.J, Levy, M.A, Eggleston, D.S, Stout, T.J, Liang, J, Schultz, L.W, Clardy, J. 登録日 1993-08-05 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS AND THE X-RAY CRYSTAL-STRUCTURES OF THEIR COMPLEXES WITH FKBP12. J.Am.Chem.Soc., 115, 1993
1FKF	ATOMIC STRUCTURE OF FKBP-FK506, AN IMMUNOPHILIN-IMMUNOSUPPRESSANT COMPLEX 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, FK506 BINDING PROTEIN 著者 Vanduyne, G.D, Standaert, R.F, Karplus, P.A, Schreiber, S.L, Clardy, J. 登録日 1991-05-07 公開日 1991-07-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex. Science, 252, 1991
1FKD	FK-506 BINDING PROTEIN: THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX WITH THE ANTAGONIST L-685,818 分子名称: 18-HYDROXYASCOMYCIN, FK506 BINDING PROTEIN 著者 Becker, J.W, Rotonda, J, Mckeever, B.M. 登録日 1992-12-02 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818. J.Biol.Chem., 268, 1993
1FKB	ATOMIC STRUCTURE OF THE RAPAMYCIN HUMAN IMMUNOPHILIN FKBP-12 COMPLEX 分子名称: FK506 BINDING PROTEIN, RAPAMYCIN IMMUNOSUPPRESSANT DRUG 著者 Van Duyne, G.D, Standaert, R.F, Schreiber, S.L, Clardy, J.C. 登録日 1992-07-02 公開日 1993-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Atomic Structure of the Rapamycin Human Immunophilin Fkbp-12 Complex J.Am.Chem.Soc., 113, 1991
1FD9	CRYSTAL STRUCTURE OF THE MACROPHAGE INFECTIVITY POTENTIATOR PROTEIN (MIP) A MAJOR VIRULENCE FACTOR FROM LEGIONELLA PNEUMOPHILA 分子名称: PROTEIN (MACROPHAGE INFECTIVITY POTENTIATOR PROTEIN), ZINC ION 著者 Riboldi-Tunnicliffe, A, Jessen, S, Konig, B, Rahfeld, J, Hacker, J, Fischer, G, Hilgenfeld, R. 登録日 2000-07-20 公開日 2001-07-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Crystal structure of Mip, a prolylisomerase from Legionella pneumophila Nat.Struct.Biol., 8, 2001
1FAP	THE STRUCTURE OF THE IMMUNOPHILIN-IMMUNOSUPPRESSANT FKBP12-RAPAMYCIN COMPLEX INTERACTING WITH HUMAN FRAP 分子名称: FK506-BINDING PROTEIN, FRAP, RAPAMYCIN IMMUNOSUPPRESSANT DRUG 著者 Choi, J, Chen, J, Schreiber, S.L, Clardy, J. 登録日 1996-03-15 公開日 1997-07-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP. Science, 273, 1996
1F40	SOLUTION STRUCTURE OF FKBP12 COMPLEXED WITH GPI-1046, A NEUROTROPHIC LIGAND 分子名称: (2S)-[3-PYRIDYL-1-PROPYL]-1-[3,3-DIMETHYL-1,2-DIOXOPENTYL]-2-PYRROLIDINECARBOXYLATE, FK506 BINDING PROTEIN (FKBP12) 著者 Sich, C, Improta, S, Cowley, D.J, Guenet, C, Merly, J.P, Teufel, M, Saudek, V. 登録日 2000-06-07 公開日 2000-11-08 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of a neurotrophic ligand bound to FKBP12 and its effects on protein dynamics. Eur.J.Biochem., 267, 2000
1EYM	FK506 BINDING PROTEIN MUTANT, HOMODIMERIC COMPLEX 分子名称: FK506 BINDING PROTEIN 著者 Rollins, C.T, Rivera, V.M, Woolfson, D.N, Keenan, T, Hatada, M, Adams, S.E, Andrade, L.J, Yaeger, D, van Schravendijk, M.R, Holt, D.A, Gilman, M, Clackson, T. 登録日 2000-05-07 公開日 2000-08-09 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A ligand-reversible dimerization system for controlling protein-protein interactions. Proc.Natl.Acad.Sci.USA, 97, 2000
1D7J	FKBP COMPLEXED WITH 4-HYDROXY-2-BUTANONE 分子名称: 4-HYDROXY-2-BUTANONE, AMMONIUM ION, PROTEIN (FK506-BINDING PROTEIN), ... 著者 Burkhard, P, Taylor, P, Walkinshaw, M.D. 登録日 1999-10-18 公開日 1999-10-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies. J.Mol.Biol., 295, 2000
1D7I	FKBP COMPLEXED WITH METHYL METHYLSULFINYLMETHYL SULFIDE (DSS) 分子名称: AMMONIUM ION, METHYL METHYLSULFINYLMETHYL SULFIDE, PROTEIN (FK506-BINDING PROTEIN), ... 著者 Burkhard, P, Taylor, P, Walkinshaw, M.D. 登録日 1999-10-18 公開日 1999-10-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies. J.Mol.Biol., 295, 2000
1D7H	FKBP COMPLEXED WITH DMSO 分子名称: AMMONIUM ION, DIMETHYL SULFOXIDE, PROTEIN (FK506-BINDING PROTEIN), ... 著者 Burkhard, P, Taylor, P, Walkinshaw, M.D. 登録日 1999-10-18 公開日 1999-10-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies. J.Mol.Biol., 295, 2000
1D6O	NATIVE FKBP 分子名称: AMMONIUM ION, PROTEIN (FK506-BINDING PROTEIN), SULFATE ION 著者 Burkhard, P, Taylor, P, Walkinshaw, M.D. 登録日 1999-10-15 公開日 1999-10-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies. J.Mol.Biol., 295, 2000
1C9H	CRYSTAL STRUCTURE OF FKBP12.6 IN COMPLEX WITH RAPAMYCIN 分子名称: FKBP12.6, RAPAMYCIN IMMUNOSUPPRESSANT DRUG 著者 Deivanayagam, C.C.S, Carson, M, Thotakura, A, Narayana, S.V.L, Chodavarapu, C.S. 登録日 1999-08-02 公開日 2000-08-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of FKBP12.6 in complex with rapamycin. Acta Crystallogr.,Sect.D, 56, 2000
1BL4	FKBP MUTANT F36V COMPLEXED WITH REMODELED SYNTHETIC LIGAND 分子名称: PROTEIN (FK506 BINDING PROTEIN), {3-[3-(3,4-DIMETHOXY-PHENYL)-1-(1-{1-[2-(3,4,5-TRIMETHOXY-PHENYL)-BUTYRYL]-PIPERIDIN-2YL}-VINYLOXY)-PROPYL]-PHENOXY}-ACETIC ACID 著者 Hatada, M.H, Clackson, T, Yang, W, Rozamus, L.W, Amara, J, Rollins, C.T, Stevenson, L.F, Magari, S.R, Wood, S.A, Courage, N.L, Lu, X, Cerasoli Junior, F, Gilman, M, Holt, D. 登録日 1998-07-23 公開日 1998-09-02 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity. Proc.Natl.Acad.Sci.USA, 95, 1998
1BKF	FK506 BINDING PROTEIN FKBP MUTANT R42K/H87V COMPLEX WITH IMMUNOSUPPRESSANT FK506 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, FK506 BINDING PROTEIN 著者 Itoh, S, Decenzo, M.T, Livingston, D.J, Pearlman, D.A, Navia, M.A. 登録日 1995-10-18 公開日 1996-08-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Conformation of Fk506 in X-Ray Structures of its Complexes with Human Recombinant Fkbp12 Mutants Bioorg.Med.Chem.Lett., 5, 1995
1B6C	CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF THE TYPE I TGF-BETA RECEPTOR IN COMPLEX WITH FKBP12 分子名称: FK506-BINDING PROTEIN, SULFATE ION, TGF-B SUPERFAMILY RECEPTOR TYPE I 著者 Huse, M, Chen, Y.-G, Massague, J, Kuriyan, J. 登録日 1999-01-13 公開日 1999-06-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12. Cell(Cambridge,Mass.), 96, 1999
1A7X	FKBP12-FK1012 COMPLEX 分子名称: BENZYL-CARBAMIC ACID [8-DEETHYL-ASCOMYCIN-8-YL]ETHYL ESTER, FKBP12 著者 Schultz, L.W, Clardy, J. 登録日 1998-03-18 公開日 1998-06-17 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Chemical inducers of dimerization: the atomic structure of FKBP12-FK1012A-FKBP12. Bioorg.Med.Chem.Lett., 8, 1998

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