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6FBB
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BU of 6fbb by Molmil
Crystal structure of 14-3-3 sigma in complex with wild-type Shroom3
分子名称: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ...
著者Leysen, S, Meijer, F.A, Milroy, L.G, Ottmann, C.
登録日2017-12-18
公開日2018-03-14
最終更新日2018-05-09
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Characterization of Coding/Noncoding Variants forSHROOM3in Patients with CKD.
J. Am. Soc. Nephrol., 29, 2018
6FAV
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BU of 6fav by Molmil
Crystal structure of C-terminal modified Tau peptide-hybrid 4.2f-I with 14-3-3sigma
分子名称: (2~{R})-2-[(~{R})-(3-methoxyphenyl)-phenyl-methyl]pyrrolidine, 14-3-3 protein sigma, ACE-ARG-THR-PRO-SEP-LEU-PRO-GLY, ...
著者Andrei, S.A, Meijer, F.A, Ottmann, C, Milroy, L.G.
登録日2017-12-18
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes.
ACS Chem Neurosci, 9, 2018
6FAW
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BU of 6faw by Molmil
Crystal structure of C-terminal modified Tau peptide-hybrid 4.2c-I with 14-3-3sigma
分子名称: (2~{R})-2-[(~{R})-[2-(2-methoxyethoxy)phenyl]-phenyl-methyl]pyrrolidine, 14-3-3 protein sigma, ACE-ARG-THR-PRO-SEP-LEU-PRO-GLY, ...
著者Andrei, S.A, Meijer, F.A, Ottmann, C, Milroy, L.G.
登録日2017-12-18
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes.
ACS Chem Neurosci, 9, 2018
6BQT
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BU of 6bqt by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and T360
分子名称: 1,2-ETHANEDIOL, 14-3-3 protein theta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ...
著者Kast, D.J, Dominguez, R.
登録日2017-11-28
公開日2018-12-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
6F08
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BU of 6f08 by Molmil
14-3-3 zeta in complex with the human Son of sevenless homolog 1 (SOS1)
分子名称: 14-3-3 protein zeta/delta, PENTAETHYLENE GLYCOL, Son of sevenless homolog 1
著者Ballone, A, Centorrino, F, Ottmann, C, Guo, S, Leysen, S.
登録日2017-11-17
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterization of 14-3-3 zeta in complex with the human Son of sevenless homolog 1 (SOS1).
J. Struct. Biol., 202, 2018
6F09
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BU of 6f09 by Molmil
Binary complex of 14-3-3 zeta with ubiquitin specific protease 8 (USP8) pSer718 peptide
分子名称: 14-3-3 protein zeta/delta, Ubiquitin carboxyl-terminal hydrolase 8
著者Centorrino, F, Ballone, A, Ottmann, C, Guo, S, Leysen, S.
登録日2017-11-17
公開日2018-03-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.594 Å)
主引用文献Biophysical and structural insight into the USP8/14-3-3 interaction.
FEBS Lett., 592, 2018
5YQG
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BU of 5yqg by Molmil
The structure of 14-3-3 and pNumb peptide
分子名称: 14-3-3 protein eta, Peptide from Protein numb homolog
著者Chen, X, Liu, Z, Wen, W.
登録日2017-11-06
公開日2018-02-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural determinants controlling 14-3-3 recruitment to the endocytic adaptor Numb and dissociation of the Numb/alpha-adaptin complex.
J. Biol. Chem., 293, 2018
6EWW
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BU of 6eww by Molmil
Structure of 14-3-3 zeta in complex with CaMKK2 14-3-3 binding motif
分子名称: 14-3-3 protein zeta/delta, ARG-LYS-LEU-SEP-LEU-GLN-GLU-ARG
著者Lentini Santo, D, Obsilova, V, Obsil, T.
登録日2017-11-06
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.679 Å)
主引用文献14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2).
Biochim. Biophys. Acta, 1862, 2018
6BCR
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BU of 6bcr by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at T340
分子名称: 1,2-ETHANEDIOL, 14-3-3 protein theta, DI(HYDROXYETHYL)ETHER, ...
著者Kast, D.J, Dominguez, R.
登録日2017-10-20
公開日2018-10-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.986 Å)
主引用文献Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
6BD1
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BU of 6bd1 by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at S366
分子名称: 14-3-3 protein theta, DI(HYDROXYETHYL)ETHER, Insulin receptor substrate protein of 53 kDa, ...
著者Kast, D.J, Dominguez, R.
登録日2017-10-20
公開日2018-10-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
6BD2
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BU of 6bd2 by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and S366
分子名称: 1,2-ETHANEDIOL, 14-3-3 protein theta, DI(HYDROXYETHYL)ETHER, ...
著者Kast, D.J, Dominguez, R.
登録日2017-10-20
公開日2018-10-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
6BCY
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BU of 6bcy by Molmil
Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at T360
分子名称: 14-3-3 protein theta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, ...
著者Kast, D.J, Dominguez, R.
登録日2017-10-20
公開日2018-10-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanism of IRSp53 inhibition by 14-3-3.
Nat Commun, 10, 2019
6EJL
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BU of 6ejl by Molmil
Structure of 14-3-3 zeta in complex with ASK1 14-3-3 binding motif
分子名称: 14-3-3 protein zeta/delta, Mitogen-activated protein kinase kinase kinase 5
著者Petrvalska, O, Lentini Santo, D, Obsilova, V, Obsil, T.
登録日2017-09-21
公開日2017-11-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.382 Å)
主引用文献Crystal structure of 14-3-3 zeta in complex with ASK1 14-3-3 binding motif
To Be Published
6EIH
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BU of 6eih by Molmil
The crystal structure of 14-3-3 epsilon in complex with the phosphorylated NELFE peptide
分子名称: 14-3-3 protein epsilon, SER-ILE-SEP-ARG
著者Akutsu, M, Wagner, S.A, Beli, P.
登録日2017-09-19
公開日2018-02-14
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage.
Nat Commun, 9, 2018
5OM0
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BU of 5om0 by Molmil
CH2 chimera of human 14-3-3 sigma with the Gli1 phosphopeptide around Ser640
分子名称: 14-3-3 protein sigma,Zinc finger protein GLI1, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION
著者Sluchanko, N.N, Tugaeva, K.V, Greive, S.J, Antson, A.A.
登録日2017-07-28
公開日2017-10-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners.
Sci Rep, 7, 2017
5OMA
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BU of 5oma by Molmil
CH3 chimera of human 14-3-3 sigma with the StARD1 peptide including Ser57
分子名称: 14-3-3 protein sigma,Steroidogenic acute regulatory protein, mitochondrial, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Sluchanko, N.N, Tugaeva, K.V, Greive, S.J, Antson, A.A.
登録日2017-07-28
公開日2017-10-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners.
Sci Rep, 7, 2017
5OK9
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BU of 5ok9 by Molmil
CH1 chimera of human 14-3-3 sigma with the HSPB6 phosphopeptide in a conformation with swapped phosphopeptides
分子名称: 14-3-3 protein sigma,Heat shock protein beta-6, DI(HYDROXYETHYL)ETHER
著者Sluchanko, N.N, Tugaeva, K.V, Greive, S.J, Antson, A.A.
登録日2017-07-25
公開日2017-10-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners.
Sci Rep, 7, 2017
5OKF
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BU of 5okf by Molmil
CH1 chimera of human 14-3-3 sigma with the HSPB6 phosphopeptide in a conformation with self-bound phosphopeptides
分子名称: 14-3-3 protein sigma,Heat shock protein beta-6, CADMIUM ION
著者Sluchanko, N.N, Tugaeva, K.V, Greive, S.J, Antson, A.A.
登録日2017-07-25
公開日2017-10-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners.
Sci Rep, 7, 2017
5WFX
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BU of 5wfx by Molmil
Structural basis for the interaction of 14-3-3beta with Tricarboxylic Acid Cycle intermediate Malate
分子名称: 14-3-3 protein beta/alpha
著者Hou, Z.Q.
登録日2017-07-12
公開日2018-05-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.651 Å)
主引用文献Structural basis for the interaction of 14-3-3 beta withTricarboxylic Acid Cycle intermediate Malate
To Be Published
5WFU
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BU of 5wfu by Molmil
Structural basis for the interaction of 14-3-3beta with Tricarboxylic Acid Cycle intermediate Malate
分子名称: 14-3-3 protein beta/alpha, D-MALATE
著者Hou, Z.Q, Liu, X.Y.
登録日2017-07-12
公開日2018-07-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural basis for the interaction of 14-3-3beta with Tricarboxylic Acid Cycle intermediate Malate
To Be Published
5OEH
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BU of 5oeh by Molmil
Molecular tweezers modulate 14-3-3 protein-protein interactions.
分子名称: (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein sigma, CHLORIDE ION, ...
著者Bier, D, Ottmann, C.
登録日2017-07-07
公開日2017-07-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Molecular tweezers modulate 14-3-3 protein-protein interactions.
Nat Chem, 5, 2013
5OEG
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BU of 5oeg by Molmil
Molecular tweezers modulate 14-3-3 protein-protein interactions
分子名称: (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, 14-3-3 protein sigma, CHLORIDE ION
著者Bier, D, Ottmann, C.
登録日2017-07-07
公開日2017-07-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Molecular tweezers modulate 14-3-3 protein-protein interactions.
Nat Chem, 5, 2013
5XY9
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BU of 5xy9 by Molmil
Structure of the MST4 and 14-3-3 complex
分子名称: 14-3-3 protein zeta/delta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, ...
著者Shi, Z.B, Zhou, Z.C.
登録日2017-07-06
公開日2018-07-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Structure of the MST4 and 14-3-3 complex
To Be Published
5NWK
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BU of 5nwk by Molmil
14-3-3c in complex with CPP and fusicoccin
分子名称: 14-3-3 c-1 protein, FUSICOCCIN, PHOSPHOSERINE, ...
著者Saponaro, A, Porro, A, Chaves-Sanjuan, A, Nardini, M, Thiel, G, Moroni, A.
登録日2017-05-06
公開日2017-11-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins.
Plant Cell, 29, 2017
5NWJ
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BU of 5nwj by Molmil
14-3-3c in complex with CPP7
分子名称: 14-3-3-like protein C, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Saponaro, A, Porro, A, Chaves-Sanjuan, A, Nardini, M, Thiel, G, Moroni, A.
登録日2017-05-06
公開日2017-11-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins.
Plant Cell, 29, 2017

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件を2024-06-26に公開中

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