PDB: 30760 件ウェブページステータス検索Chemie searchBIRD

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7C7F	Crystal structures of AKR1C3 binary complex with NADP+ 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Aldo-keto reductase family 1 member C3, ... 著者 Irie, K, Toyooka, N, Endo, S. 登録日 2020-05-25 公開日 2020-09-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Development of Novel AKR1C3 Inhibitors as New Potential Treatment for Castration-Resistant Prostate Cancer. J.Med.Chem., 63, 2020
4UH9	Structure of bovine endothelial nitric oxide synthase heme domain in complex with N1-(3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)-5- fluorophenyl)-N1,N2-dimethylethane-1,2-diamine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, GLYCEROL, ... 著者 Li, H, Poulos, T.L. 登録日 2015-03-23 公開日 2015-07-15 最終更新日 2015-08-05 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 2-Aminopyridines with a Truncated Side Chain to Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity. J.Med.Chem., 58, 2015
5KUR	Human cyclophilin A at 100K, Data set 5 分子名称: Peptidyl-prolyl cis-trans isomerase A 著者 Russi, S, Gonzalez, A, Kenner, L.R, Keedy, D.A, Fraser, J.S, van den Bedem, H. 登録日 2016-07-13 公開日 2016-09-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Conformational variation of proteins at room temperature is not dominated by radiation damage. J Synchrotron Radiat, 24, 2017
4UFK	Mouse Galactocerebrosidase complexed with dideoxy-imino-lyxitol DIL 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E. 登録日 2015-03-17 公開日 2015-03-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.402 Å) 主引用文献 Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease. Chem.Sci., 6, 2015
8SIP	Structure of a mouse IgG antibody fragment that binds Inosine, an RNA modification 分子名称: INOSINE, Inosine binding IgG Fab, heavy chain, ... 著者 Aoki, S.T. 登録日 2023-04-16 公開日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Structure of a mouse IgG antibody fragment that binds Inosine, an RNA modification To Be Published
7C8W	Structure of sybody MR17 in complex with the SARS-CoV-2 S receptor-binding domain (RBD) 分子名称: GLYCEROL, Spike protein S1, Synthetic nanobody MR17, ... 著者 Li, T, Cai, H, Yao, H, Qin, W, Li, D. 登録日 2020-06-03 公開日 2020-06-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection. Nat Commun, 12, 2021
7CC4	A biodegradable plastic-degrading cutinase-like enzyme from the phyllosphere yeast Pseudozyma antarctica 分子名称: Cutinase-like enzyme, SODIUM ION 著者 Suzuki, K, Watanabe, T, Kitamoto, H. 登録日 2020-06-16 公開日 2020-07-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A biodegradable plastic-degrading cutinase-like enzyme from the phyllosphere yeast Pseudozyma antarctica To Be Published
4UGY	Structure of Bacillus subtilis Nitric Oxide Synthase in complex with N1-(5-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyridin-3-yl)-N1,N2- dimethylethane-1,2-diamine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, CHLORIDE ION, GLYCEROL, ... 著者 Holden, J.K, Poulos, T.L. 登録日 2015-03-22 公開日 2015-06-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Inhibitor Bound Crystal Structures of Bacterial Nitric Oxide Synthase. Biochemistry, 54, 2015
8SUD	JC Polyomavirus LTA NLS bound to importin alpha 2 分子名称: Importin subunit alpha-1, Large T antigen 著者 Cross, E.M, Forwood, J.K, Alvisi, G. 登録日 2023-05-12 公開日 2024-02-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8SWE	FGFR2 Kinase Domain Bound to Reversible Inhibitor Cmpd 3 分子名称: Fibroblast growth factor receptor 2, GLUTATHIONE, GLYCEROL, ... 著者 Valverde, R, Foster, L. 登録日 2023-05-18 公開日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2. Proc.Natl.Acad.Sci.USA, 121, 2024
5KYD	Crystal structure of USP7 catalytic domain [V302K] mutant in complex with ubiquitin 分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7 著者 Rouge, L, Ozen, A. 登録日 2016-07-21 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation. Structure, 26, 2018
7CCA	Crystal structure of White Spot Syndrome Virus Thymidylate Synthase - ternary complex with Methotrexate and dUMP 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, METHOTREXATE, Thymidylate Synthase 著者 Panchal, N.V, Kumar, S, Shaikh, N, Vasudevan, D. 登録日 2020-06-16 公開日 2020-11-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structure analysis of thymidylate synthase from white spot syndrome virus reveals WSSV-specific structural elements. Int.J.Biol.Macromol., 167, 2021
7CQY	Tetrathionate hydrolase from Acidithiobacillus ferrooxidans mutant - D325N 分子名称: SULFATE ION, Tetrathionate hydrolase 著者 Tamada, T, Hirano, Y. 登録日 2020-08-12 公開日 2021-01-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.80035782 Å) 主引用文献 Reaction mechanism of tetrathionate hydrolysis based on the crystal structure of tetrathionate hydrolase from Acidithiobacillus ferrooxidans. Protein Sci., 30, 2020
4UP5	Crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a chemical fragment 分子名称: 6-methoxy-1,3-benzothiazol-2-amine, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ... 著者 Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M. 登録日 2014-06-12 公開日 2014-11-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger. Acs Chem.Biol., 9, 2014
8SDD	Crystal structure of fluoroacetate dehalogenase Daro3835 H274N mutant with D107-glycolyl intermediate 分子名称: Alpha/beta hydrolase fold protein 著者 Stogios, P.J, Skarina, T, Khusnutdinova, A, Iakounine, A, Savchenko, A. 登録日 2023-04-06 公開日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases. Febs J., 290, 2023
7CDI	Crystal structure of SARS-CoV-2 antibody P2C-1F11 with RBD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P2C-1F11 heavy chain, ... 著者 Wang, X, Zhang, L, Ge, J, Wang, R. 登録日 2020-06-19 公開日 2020-11-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry. Nat Commun, 12, 2021
8SSH	MtrR from Neisseria gonorrhoeae bound to Ethinyl Estradiol 分子名称: Ethinyl estradiol, HTH-type transcriptional regulator MtrR, PHOSPHATE ION 著者 Hooks, G.M, Brennan, R.G. 登録日 2023-05-08 公開日 2024-02-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR. Nat Commun, 15, 2024
8SY2	Peanut USP-type BURP Domain Peptide Cyclase 分子名称: BURP domain-containing protein 著者 Mydy, L.S, Kersten, R.D, Smith, J.L. 登録日 2023-05-24 公開日 2024-02-14 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 An intramolecular macrocyclase in plant ribosomal peptide biosynthesis. Nat.Chem.Biol., 20, 2024
5L2L	Nab2 Zn fingers 5-7 bound to A11G RNA 分子名称: Nab2p, RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*G)-3'), ZINC ION 著者 Stewart, M, Aibara, S. 登録日 2016-08-02 公開日 2016-12-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural basis for the dimerization of Nab2 generated by RNA binding provides insight into its contribution to both poly(A) tail length determination and transcript compaction in Saccharomyces cerevisiae. Nucleic Acids Res., 45, 2017
5L1V	X-ray Structure of M81C mutant of Cytochrome P450 PntM with pentalenolactone F 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone F 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016
7CU0	Crystal structure of Streptomyces albogriseolus flavin-dependent tryptophan 6-halogenase Thal in complex with tryptophan 分子名称: TRYPTOPHAN, Tryptophan 6-halogenase 著者 Chitnumsub, P, Jaruwat, A, Phintha, A, Chaiyen, P. 登録日 2020-08-20 公開日 2020-11-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Dissecting the low catalytic capability of flavin-dependent halogenases. J.Biol.Chem., 296, 2020
8SKQ	RNA oligonucleotide containing an alpha-(L)-threofuranosyl nucleic acid (TNA) 分子名称: TNA-containing RNA oligonucleotide 著者 Harp, J.M, Egli, M. 登録日 2023-04-20 公開日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Shorter Is Better: The alpha-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs. J.Am.Chem.Soc., 145, 2023
5L3F	LSD1-CoREST1 in complex with polymyxin B 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, Polmyxin B, ... 著者 Speranzini, V, Rotili, D, Ciossani, G, Pilotto, S, Forgione, M, Lucidi, A, Forneris, F, Velankar, S, Mai, A, Mattevi, A. 登録日 2016-04-10 公開日 2016-09-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features. Sci Adv, 2, 2016
4UP7	Crystal structure of Entamoeba histolytica lysyl-tRNA synthetase in complex with lysyl-adenylate 分子名称: ADENOSINE-5'-[LYSYL-PHOSPHATE], LYSINE--TRNA LIGASE 著者 Bonnefond, L, Nureki, O. 登録日 2014-06-14 公開日 2014-10-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.789 Å) 主引用文献 Crystal Structures of Entamoeba Histolytica Lysyl-tRNA Synthetase Reveal Conformational Changes Upon Lysine Binding and a Specific Helix Bundle Domain. FEBS Lett., 588, 2014
5L3T	Structure of the Saccharomyces cerevisiae TREX-2 complex 分子名称: 26S proteasome complex subunit SEM1, Nuclear mRNA export protein SAC3, Nuclear mRNA export protein THP1, ... 著者 Stewart, M, Aibara, S. 登録日 2016-05-24 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (4.927 Å) 主引用文献 The Sac3 TPR-like region in the Saccharomyces cerevisiae TREX-2 complex is more extensive but independent of the CID region. J. Struct. Biol., 195, 2016

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