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1M8V
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Structure of Pyrococcus abyssii Sm Protein in Complex with a Uridine Heptamer
分子名称: 5'-R(P*UP*UP*UP*UP*UP*UP*U)-3', CALCIUM ION, PUTATIVE SNRNP SM-LIKE PROTEIN, ...
著者Thore, S, Mayer, C, Sauter, C, Weeks, S, Suck, D.
登録日2002-07-26
公開日2003-02-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Pyrococcus abyssii Sm core and its Complex with RNA: Common Features of RNA-binding in Archaea and Eukarya
J.Biol.Chem., 278, 2003
4U7W
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BU of 4u7w by Molmil
The crystal structure of the terminal R domain from the myxalamid PKS-NRPS biosynthetic pathway
分子名称: ACETATE ION, MxaA, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Tsai, S.C, Keasling, J.D, Luo, R, Barajas, J.F, Phelan, R.M, Schaub, A.J, Kliewer, J.
登録日2014-07-31
公開日2015-08-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.899 Å)
主引用文献Comprehensive Structural and Biochemical Analysis of the Terminal Myxalamid Reductase Domain for the Engineered Production of Primary Alcohols.
Chem.Biol., 22, 2015
4TWD
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BU of 4twd by Molmil
X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with memantine
分子名称: Cys-loop ligand-gated ion channel, Memantine
著者Ulens, C, Spurny, R, Thompson, A.J, Alqazzaz, M, Debaveye, S, Lu, H, Price, K, Villalgordo, J.M, Tresadern, G, Lynch, J.W, Lummis, S.C.R.
登録日2014-06-30
公開日2014-09-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine.
Structure, 22, 2014
4U2B
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BU of 4u2b by Molmil
Crystal structure of dienelactone hydrolase (C123S) at 1.70 A resolution
分子名称: Carboxymethylenebutenolidase, SULFATE ION
著者Porter, J.L, Collyer, C.A, Ollis, D.L.
登録日2014-07-16
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Directed evolution of new and improved enzyme functions using an evolutionary intermediate and multidirectional search.
Acs Chem.Biol., 10, 2015
4U2E
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BU of 4u2e by Molmil
Crystal structure of dienelactone hydrolase S-3 variant (Q35H, F38L, Q110L, C123S, Y137C, Y145C, N154D, E199G, S208G, G211D and K234N) at 1.70 A resolution
分子名称: Carboxymethylenebutenolidase, SULFATE ION
著者Porter, J.L, Collyer, C.A, Ollis, D.L.
登録日2014-07-16
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Directed evolution of new and improved enzyme functions using an evolutionary intermediate and multidirectional search.
Acs Chem.Biol., 10, 2015
4U2F
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BU of 4u2f by Molmil
Crystal structure of dienelactone hydrolase B-1 variant (Q35H, F38L, Y64H, Q110L, C123S, Y137C, Y145C, N154D, E199G, S208G and G211D) at 1.80 A resolution
分子名称: Carboxymethylenebutenolidase, SULFATE ION
著者Porter, J.L, Collyer, C.A, Ollis, D.L.
登録日2014-07-16
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Directed evolution of new and improved enzyme functions using an evolutionary intermediate and multidirectional search.
Acs Chem.Biol., 10, 2015
4TWH
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BU of 4twh by Molmil
X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) mutant F16'S
分子名称: Cys-loop ligand-gated ion channel
著者Ulens, C, Spurny, R, Thompson, A.J, Alqazzaz, M, Debaveye, S, Lu, H, Price, K, Villalgordo, J.M, Tresadern, G, Lynch, J.W, Lummis, S.C.R.
登録日2014-06-30
公開日2014-09-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine.
Structure, 22, 2014
4TWF
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BU of 4twf by Molmil
X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromomemantine
分子名称: Bromomemantine, Cys-loop ligand-gated ion channel
著者Ulens, C, Spurny, R, Thompson, A.J, Alqazzaz, M, Debaveye, S, Lu, H, Price, K, Villalgordo, J.M, Tresadern, G, Lynch, J.W, Lummis, S.C.R.
登録日2014-06-30
公開日2014-09-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.901 Å)
主引用文献The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine.
Structure, 22, 2014
1ZYL
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BU of 1zyl by Molmil
Crystal Structure of Hypothetical Protein YihE from Escherichia coli
分子名称: Hypothetical protein yihE
著者Zheng, J, Jia, Z, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2005-06-10
公開日2006-09-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a novel prokaryotic Ser/Thr kinase and its implication in the Cpx stress response pathway.
Mol.Microbiol., 63, 2007
4U2C
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BU of 4u2c by Molmil
Crystal structure of dienelactone hydrolase A-6 variant (S7T, A24V, Q35H, F38L, Q110L, C123S, Y145C, E199G and S208G) at 1.95 A resolution
分子名称: Carboxymethylenebutenolidase, SULFATE ION
著者Porter, J.L, Collyer, C.A, Ollis, D.L.
登録日2014-07-16
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Directed evolution of new and improved enzyme functions using an evolutionary intermediate and multidirectional search.
Acs Chem.Biol., 10, 2015
4U2D
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BU of 4u2d by Molmil
Crystal structure of dienelactone hydrolase S-2 variant (Q35H, F38L, Q110L, C123S, Y137C, Y145C, N154D, E199G, S208G and G211D) at 1.67 A resolution
分子名称: Carboxymethylenebutenolidase, SULFATE ION
著者Porter, J.L, Collyer, C.A, Ollis, D.L.
登録日2014-07-16
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Directed evolution of new and improved enzyme functions using an evolutionary intermediate and multidirectional search.
Acs Chem.Biol., 10, 2015
4U2G
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BU of 4u2g by Molmil
Crystal structure of dienelactone hydrolase B-4 variant (Q35H, F38L, Y64H, Q76L, Q110L, C123S, Y137C, A141V, Y145C, N154D, E199G, S208G, G211D, S233G and 237Q) at 1.80 A resolution
分子名称: Carboxymethylenebutenolidase, SULFATE ION
著者Porter, J.L, Collyer, C.A, Ollis, D.L.
登録日2014-07-16
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Directed evolution of new and improved enzyme functions using an evolutionary intermediate and multidirectional search.
Acs Chem.Biol., 10, 2015
2LC5
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BU of 2lc5 by Molmil
Calmodulin-like Protein from Entamoeba histolytica: Solution Structure and Calcium-Binding Properties of a Partially Folded Protein
分子名称: CALCIUM ION, Calmodulin, putative
著者Rout, A.K, Padhan, N, Barnwal, R.P, Bhattacharya, A, Chary, K.V.
登録日2011-04-23
公開日2011-06-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Calmodulin like protein from Entamoeba histolytica: solution structure and calcium binding properties of a partially folded protein.
Biochemistry, 50, 2010
4UFB
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BU of 4ufb by Molmil
Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with Lys-Pro
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, CHLORIDE ION, ...
著者Masuyer, G, Douglas, R.G, Sturrock, E.D, Acharya, K.R.
登録日2015-03-16
公開日2015-10-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of Ac-Sdkp Hydrolysis by Angiotensin-I Converting Enzyme
Sci.Rep., 5, 2015
4UFA
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BU of 4ufa by Molmil
Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with Ac-SD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, ...
著者Masuyer, G, Douglas, R.G, Sturrock, E.D, Acharya, K.R.
登録日2015-03-16
公開日2015-10-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of Ac-Sdkp Hydrolysis by Angiotensin-I Converting Enzyme
Sci.Rep., 5, 2015
4UW6
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BU of 4uw6 by Molmil
Human galectin-7 in complex with a galactose based dendron D3
分子名称: DENDRON-D3, GALECTIN-7
著者Ramaswamy, S, Sleiman, M.H, Masuyer, G, Arbez-Gindre, C, Micha-Screttas, M, Calogeropoulou, T, Steele, B.R, Acharya, K.R.
登録日2014-08-08
公開日2014-11-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural Basis of Multivalent Galactose-Based Dendrimer Recognition by Human Galectin-7.
FEBS J., 282, 2015
2EUD
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BU of 2eud by Molmil
Structures of Yeast Ribonucleotide Reductase I complexed with Ligands and Subunit Peptides
分子名称: GEMCITABINE DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Dealwis, C, Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J.
登録日2005-10-28
公開日2006-03-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1OX6
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BU of 1ox6 by Molmil
TOWARDS UNDERSTANDING THE MECHANISM OF THE COMPLEX CYCLIZATION REACTION CATALYZED BY IMIDAZOLE GLYCEROPHOSPHATE SYNTHASE
分子名称: Imidazole glycerol phosphate synthase hisHF, NICKEL (II) ION, PYROPHOSPHATE 2-, ...
著者Chaudhuri, B.N, Smith, J.L.
登録日2003-04-01
公開日2003-06-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Towards Understanding the Mechanism of the Complex Cyclization Reaction Catalyzed by Imidazole Glycerophosphate Synthase: Crystal Structures of a Ternary Complex and the Free Enzyme
Biochemistry, 42, 2003
1OX4
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BU of 1ox4 by Molmil
TOWARDS UNDERSTANDING THE MECHANISM OF THE COMPLEX CYCLIZATION REACTION CATALYZED BY IMIDAZOLE GLYCEROPHOSPHATE SYNTHASE
分子名称: Imidazole glycerol phosphate synthase hisHF, NICKEL (II) ION, PYROPHOSPHATE 2-, ...
著者Chaudhuri, B.N, Smith, J.L.
登録日2003-04-01
公開日2003-06-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Towards Understanding the Mechanism of the Complex Cyclization Reaction Catalyzed by Imidazole Glycerophosphate Synthase: Crystal Structures of a Ternary Complex and the Free Enzyme
Biochemistry, 42, 2003
1JU8
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BU of 1ju8 by Molmil
Solution structure of Leginsulin, a plant hormon
分子名称: Leginsulin
著者Yamazaki, T, Takaoka, M, Katoh, E, Hanada, K, Sakita, M, Sakata, K, Nishiuchi, Y, Hirano, H.
登録日2001-08-23
公開日2003-06-17
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献A possible physiological function and the tertiary structure of a 4-kDa peptide in legumes
EUR.J.BIOCHEM., 270, 2003
8I0C
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BU of 8i0c by Molmil
Crystal structure of Aldo-keto reductase 1C3 complexed with compound S0703
分子名称: 1-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Jiang, J, He, S, Liu, Y, Fang, P, Sun, H.
登録日2023-01-10
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Development of Biaryl-Containing Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors for Reversing AKR1C3-Mediated Drug Resistance in Cancer Treatment.
J.Med.Chem., 66, 2023
4M3Y
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BU of 4m3y by Molmil
RB69 DNA polymerase ternary complex with dG/dT at position n-1 of primer/template duplex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
著者Xia, S, Konigsberg, W.H.
登録日2013-08-06
公開日2014-02-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant.
Protein Sci., 23, 2014
8IFM
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BU of 8ifm by Molmil
Cryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 2
分子名称: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ...
著者Zhang, J.T, Jia, N.
登録日2023-02-18
公開日2024-01-17
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
8IFL
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BU of 8ifl by Molmil
Cryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 1
分子名称: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ...
著者Zhang, J.T, Jia, N.
登録日2023-02-18
公開日2024-01-17
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
6WVX
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BU of 6wvx by Molmil
Crystal structure of the first bromodomain of human BRD4 with benzodiazepine inhibitor
分子名称: 6'-(4-chlorophenyl)-1'-methyl-8'-(1-methyl-1H-pyrazol-4-yl)spiro[cyclopropane-1,4'-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine], Bromodomain-containing protein 4
著者Eron, S.J.
登録日2020-05-07
公開日2021-09-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural Characterization of Degrader-Induced Ternary Complexes Using Hydrogen-Deuterium Exchange Mass Spectrometry and Computational Modeling: Implications for Structure-Based Design.
Acs Chem.Biol., 16, 2021

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