1M8V
| Structure of Pyrococcus abyssii Sm Protein in Complex with a Uridine Heptamer | 分子名称: | 5'-R(P*UP*UP*UP*UP*UP*UP*U)-3', CALCIUM ION, PUTATIVE SNRNP SM-LIKE PROTEIN, ... | 著者 | Thore, S, Mayer, C, Sauter, C, Weeks, S, Suck, D. | 登録日 | 2002-07-26 | 公開日 | 2003-02-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of Pyrococcus abyssii Sm core and its Complex with RNA: Common Features of RNA-binding in Archaea and Eukarya J.Biol.Chem., 278, 2003
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4U7W
| The crystal structure of the terminal R domain from the myxalamid PKS-NRPS biosynthetic pathway | 分子名称: | ACETATE ION, MxaA, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Tsai, S.C, Keasling, J.D, Luo, R, Barajas, J.F, Phelan, R.M, Schaub, A.J, Kliewer, J. | 登録日 | 2014-07-31 | 公開日 | 2015-08-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | 主引用文献 | Comprehensive Structural and Biochemical Analysis of the Terminal Myxalamid Reductase Domain for the Engineered Production of Primary Alcohols. Chem.Biol., 22, 2015
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4TWD
| X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with memantine | 分子名称: | Cys-loop ligand-gated ion channel, Memantine | 著者 | Ulens, C, Spurny, R, Thompson, A.J, Alqazzaz, M, Debaveye, S, Lu, H, Price, K, Villalgordo, J.M, Tresadern, G, Lynch, J.W, Lummis, S.C.R. | 登録日 | 2014-06-30 | 公開日 | 2014-09-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine. Structure, 22, 2014
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4U2B
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4U2E
| Crystal structure of dienelactone hydrolase S-3 variant (Q35H, F38L, Q110L, C123S, Y137C, Y145C, N154D, E199G, S208G, G211D and K234N) at 1.70 A resolution | 分子名称: | Carboxymethylenebutenolidase, SULFATE ION | 著者 | Porter, J.L, Collyer, C.A, Ollis, D.L. | 登録日 | 2014-07-16 | 公開日 | 2014-12-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Directed evolution of new and improved enzyme functions using an evolutionary intermediate and multidirectional search. Acs Chem.Biol., 10, 2015
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4U2F
| Crystal structure of dienelactone hydrolase B-1 variant (Q35H, F38L, Y64H, Q110L, C123S, Y137C, Y145C, N154D, E199G, S208G and G211D) at 1.80 A resolution | 分子名称: | Carboxymethylenebutenolidase, SULFATE ION | 著者 | Porter, J.L, Collyer, C.A, Ollis, D.L. | 登録日 | 2014-07-16 | 公開日 | 2014-12-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Directed evolution of new and improved enzyme functions using an evolutionary intermediate and multidirectional search. Acs Chem.Biol., 10, 2015
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4TWH
| X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) mutant F16'S | 分子名称: | Cys-loop ligand-gated ion channel | 著者 | Ulens, C, Spurny, R, Thompson, A.J, Alqazzaz, M, Debaveye, S, Lu, H, Price, K, Villalgordo, J.M, Tresadern, G, Lynch, J.W, Lummis, S.C.R. | 登録日 | 2014-06-30 | 公開日 | 2014-09-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine. Structure, 22, 2014
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4TWF
| X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromomemantine | 分子名称: | Bromomemantine, Cys-loop ligand-gated ion channel | 著者 | Ulens, C, Spurny, R, Thompson, A.J, Alqazzaz, M, Debaveye, S, Lu, H, Price, K, Villalgordo, J.M, Tresadern, G, Lynch, J.W, Lummis, S.C.R. | 登録日 | 2014-06-30 | 公開日 | 2014-09-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.901 Å) | 主引用文献 | The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine. Structure, 22, 2014
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1ZYL
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4U2C
| Crystal structure of dienelactone hydrolase A-6 variant (S7T, A24V, Q35H, F38L, Q110L, C123S, Y145C, E199G and S208G) at 1.95 A resolution | 分子名称: | Carboxymethylenebutenolidase, SULFATE ION | 著者 | Porter, J.L, Collyer, C.A, Ollis, D.L. | 登録日 | 2014-07-16 | 公開日 | 2014-12-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Directed evolution of new and improved enzyme functions using an evolutionary intermediate and multidirectional search. Acs Chem.Biol., 10, 2015
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4U2D
| Crystal structure of dienelactone hydrolase S-2 variant (Q35H, F38L, Q110L, C123S, Y137C, Y145C, N154D, E199G, S208G and G211D) at 1.67 A resolution | 分子名称: | Carboxymethylenebutenolidase, SULFATE ION | 著者 | Porter, J.L, Collyer, C.A, Ollis, D.L. | 登録日 | 2014-07-16 | 公開日 | 2014-12-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Directed evolution of new and improved enzyme functions using an evolutionary intermediate and multidirectional search. Acs Chem.Biol., 10, 2015
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4U2G
| Crystal structure of dienelactone hydrolase B-4 variant (Q35H, F38L, Y64H, Q76L, Q110L, C123S, Y137C, A141V, Y145C, N154D, E199G, S208G, G211D, S233G and 237Q) at 1.80 A resolution | 分子名称: | Carboxymethylenebutenolidase, SULFATE ION | 著者 | Porter, J.L, Collyer, C.A, Ollis, D.L. | 登録日 | 2014-07-16 | 公開日 | 2014-12-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Directed evolution of new and improved enzyme functions using an evolutionary intermediate and multidirectional search. Acs Chem.Biol., 10, 2015
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2LC5
| Calmodulin-like Protein from Entamoeba histolytica: Solution Structure and Calcium-Binding Properties of a Partially Folded Protein | 分子名称: | CALCIUM ION, Calmodulin, putative | 著者 | Rout, A.K, Padhan, N, Barnwal, R.P, Bhattacharya, A, Chary, K.V. | 登録日 | 2011-04-23 | 公開日 | 2011-06-08 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Calmodulin like protein from Entamoeba histolytica: solution structure and calcium binding properties of a partially folded protein. Biochemistry, 50, 2010
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4UFB
| Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with Lys-Pro | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, CHLORIDE ION, ... | 著者 | Masuyer, G, Douglas, R.G, Sturrock, E.D, Acharya, K.R. | 登録日 | 2015-03-16 | 公開日 | 2015-10-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Basis of Ac-Sdkp Hydrolysis by Angiotensin-I Converting Enzyme Sci.Rep., 5, 2015
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4UFA
| Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with Ac-SD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME, ... | 著者 | Masuyer, G, Douglas, R.G, Sturrock, E.D, Acharya, K.R. | 登録日 | 2015-03-16 | 公開日 | 2015-10-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Basis of Ac-Sdkp Hydrolysis by Angiotensin-I Converting Enzyme Sci.Rep., 5, 2015
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4UW6
| Human galectin-7 in complex with a galactose based dendron D3 | 分子名称: | DENDRON-D3, GALECTIN-7 | 著者 | Ramaswamy, S, Sleiman, M.H, Masuyer, G, Arbez-Gindre, C, Micha-Screttas, M, Calogeropoulou, T, Steele, B.R, Acharya, K.R. | 登録日 | 2014-08-08 | 公開日 | 2014-11-12 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structural Basis of Multivalent Galactose-Based Dendrimer Recognition by Human Galectin-7. FEBS J., 282, 2015
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2EUD
| Structures of Yeast Ribonucleotide Reductase I complexed with Ligands and Subunit Peptides | 分子名称: | GEMCITABINE DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Dealwis, C, Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J. | 登録日 | 2005-10-28 | 公開日 | 2006-03-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1OX6
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1OX4
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1JU8
| Solution structure of Leginsulin, a plant hormon | 分子名称: | Leginsulin | 著者 | Yamazaki, T, Takaoka, M, Katoh, E, Hanada, K, Sakita, M, Sakata, K, Nishiuchi, Y, Hirano, H. | 登録日 | 2001-08-23 | 公開日 | 2003-06-17 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | A possible physiological function and the tertiary structure of a 4-kDa peptide in legumes EUR.J.BIOCHEM., 270, 2003
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8I0C
| Crystal structure of Aldo-keto reductase 1C3 complexed with compound S0703 | 分子名称: | 1-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Jiang, J, He, S, Liu, Y, Fang, P, Sun, H. | 登録日 | 2023-01-10 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Development of Biaryl-Containing Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors for Reversing AKR1C3-Mediated Drug Resistance in Cancer Treatment. J.Med.Chem., 66, 2023
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4M3Y
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8IFM
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8IFL
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6WVX
| Crystal structure of the first bromodomain of human BRD4 with benzodiazepine inhibitor | 分子名称: | 6'-(4-chlorophenyl)-1'-methyl-8'-(1-methyl-1H-pyrazol-4-yl)spiro[cyclopropane-1,4'-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine], Bromodomain-containing protein 4 | 著者 | Eron, S.J. | 登録日 | 2020-05-07 | 公開日 | 2021-09-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural Characterization of Degrader-Induced Ternary Complexes Using Hydrogen-Deuterium Exchange Mass Spectrometry and Computational Modeling: Implications for Structure-Based Design. Acs Chem.Biol., 16, 2021
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