PDB: 45118 件ウェブページステータス検索Chemie searchBIRD

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4ZIX	Structure of HEWL using Serial Femtosecond Crystallography of Soluble Proteins in Lipidic Cubic Phase 分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION 著者 Fromme, R, Ishchenko, A, Metz, M, Roy-Chowdhury, S, Basu, S, Boutet, S, Fromme, P, White, T.A, Barty, A, Spence, J.C.H, Weierstall, U, Liu, W, Cherezov, V. 登録日 2015-04-28 公開日 2015-08-12 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Serial Femtosecond Crystallography of Soluble Proteins in Lipidic Cubic Phase IUCrJ, 2, 2015
1MMX	Crystal structure of galactose mutarotase from Lactococcus lactis complexed with D-fucose 分子名称: Aldose 1-epimerase, SODIUM ION, alpha-L-fucopyranose 著者 Thoden, J.B, Kim, J, Raushel, F.M, Holden, H.M. 登録日 2002-09-04 公開日 2002-09-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and kinetic studies of sugar binding to galactose mutarotase from Lactococcus lactis. J.Biol.Chem., 277, 2002
6E3R	Structure of human DNA polymerase beta complexed with 8OA as the template base in a 1-nucleotide gapped DNA 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2018-07-14 公開日 2019-04-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases. J. Am. Chem. Soc., 141, 2019
6DZ4	Crystal structure of Salmonella typhimurium Tryptophan Synthase with sodium ion at the metal coordination site and (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine at the beta-site 分子名称: (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Hilario, E, Dunn, M.F, Mueller, L.J, Fan, L. 登録日 2018-07-02 公開日 2019-07-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of Salmonella typhimurium Tryptophan Synthase with sodium ion at the metal coordination site and (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine at the beta site To be Published
6E3V	Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable TTP 分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2018-07-15 公開日 2019-04-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases. J. Am. Chem. Soc., 141, 2019
6E3W	Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable GTP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2018-07-15 公開日 2019-04-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases. J. Am. Chem. Soc., 141, 2019
1WKY	Crystal structure of alkaline mannanase from Bacillus sp. strain JAMB-602: catalytic domain and its Carbohydrate Binding Module 分子名称: CALCIUM ION, CHLORIDE ION, SODIUM ION, ... 著者 Akita, M, Takeda, N, Hirasawa, K, Sakai, H, Kawamoto, M, Yamamoto, M, Grant, W.D, Hatada, Y, Ito, S, Horikoshi, K. 登録日 2004-06-15 公開日 2005-06-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystallization and preliminary X-ray study of alkaline mannanase from an alkaliphilic Bacillus isolate. Acta Crystallogr.,Sect.D, 60, 2004
6E3X	Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable ATP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2018-07-15 公開日 2019-04-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable ATP To Be Published
4Z6F	Structure of human DNA polymerase beta 279NA mutant complexed with G in the template base paired with incoming non-hydrolyzable TTP and MANGANESE 分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2015-04-04 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.444 Å) 主引用文献 Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase beta. Biochem. J., 475, 2018
3I4Q	Structure of a putative inorganic pyrophosphatase from the oil-degrading bacterium Oleispira antarctica 分子名称: APC40078, SODIUM ION 著者 Singer, A.U, Evdokimova, E, Kagan, O, Edwards, A.M, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) 登録日 2009-07-02 公開日 2009-07-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica. Nat Commun, 4, 2013
4ZLS	HIV-1 wild Type protease with GRL-096-13A (a Boc-derivative P2-Ligand, 3,-5-dimethylbiphenyl P1-Ligand) 分子名称: ACETATE ION, CHLORIDE ION, Protease, ... 著者 Wang, Y.-F, Agniswamy, J, Weber, I.T. 登録日 2015-05-01 公開日 2015-07-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Structure-Based Design of Potent HIV-1 Protease Inhibitors with Modified P1-Biphenyl Ligands: Synthesis, Biological Evaluation, and Enzyme-Inhibitor X-ray Structural Studies. J.Med.Chem., 58, 2015
4ZJU	Structure of a NADH-dependent enoyl-ACP reductase from Acinetobacter baumannii in complex with NAD 分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2015-04-29 公開日 2015-05-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Structure of a NADH-dependent enoyl-ACP reductase from Acinetobacter baumannii in complex with NAD to be published
1N11	D34 REGION OF HUMAN ANKYRIN-R AND LINKER 分子名称: Ankyrin, BROMIDE ION, CHLORIDE ION 著者 Michaely, P, Tomchick, D.R, Machius, M, Anderson, R.G.W. 登録日 2002-10-16 公開日 2002-12-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of a 12 ANK repeat stack from human ankyrinR Embo J., 21, 2002
6E6G	KRAS G13D bound to GDP (K13GDP) 分子名称: CALCIUM ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Johnson, C.W, Mattos, C. 登録日 2018-07-24 公開日 2019-07-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D. Cell Rep, 28, 2019
1J70	CRYSTAL STRUCTURE OF YEAST ATP SULFURYLASE 分子名称: ATP SULPHURYLASE, PHOSPHATE ION, SODIUM ION 著者 Lalor, D.J, Schnyder, T, Saridakis, V, Pilloff, D.E, Dong, A, Tang, H, Leyh, T.S, Pai, E.F. 登録日 2001-05-15 公開日 2003-06-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and functional analysis of a truncated form of Saccharomyces cerevisiae ATP sulfurylase: C-terminal domain essential for oligomer formation but not for activity. Protein Eng., 16, 2003
6EPZ	Structure of the periplasmic binding protein MelB (Atu4661) in complex with melibiose from Agrobacterium fabrum C58 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Vigouroux, A, Morera, S. 登録日 2017-10-12 公開日 2018-04-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The plant defense signal galactinol is specifically used as a nutrient by the bacterial pathogenAgrobacterium fabrum. J. Biol. Chem., 293, 2018
6E7J	HIV-1 wild type protease with GRL-042-17A, 3-phenylhexahydro-2h-cyclopenta[d]oxazol-2-one with a bicyclic oxazolidinone scaffold as the P2 ligand 分子名称: (3aS,5R,6aR)-2-oxo-3-phenylhexahydro-2H-cyclopenta[d][1,3]oxazol-5-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, CHLORIDE ION, Protease, ... 著者 Wang, Y.-F, Agniswamy, J, Weber, I.T. 登録日 2018-07-26 公開日 2018-11-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Design and Synthesis of Potent HIV-1 Protease Inhibitors Containing Bicyclic Oxazolidinone Scaffold as the P2 Ligands: Structure-Activity Studies and Biological and X-ray Structural Studies. J. Med. Chem., 61, 2018
3HTL	Structure of the Corynebacterium diphtheriae major pilin SpaA points to a modular pilus assembly with stabilizing isopeptide bonds 分子名称: CALCIUM ION, Putative surface-anchored fimbrial subunit, SODIUM ION 著者 Kang, H.J, Paterson, N.G, Gaspar, A.H, Ton-That, H, Baker, E.N. 登録日 2009-06-11 公開日 2009-09-15 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Corynebacterium diphtheriae shaft pilin SpaA is built of tandem Ig-like modules with stabilizing isopeptide and disulfide bonds Proc.Natl.Acad.Sci.USA, 106, 2009
3I6O	Crystal structure of wild type HIV-1 protease with macrocyclic inhibitor GRL-0216A 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(1S,2R)-1-benzyl-2-hydroxy-3-[(7E)-13-methoxy-1,1-dioxido-3,4,5,6,9,10-hexahydro-2H-11,1,2-benzoxathiazacyclotridecin-2-yl]propyl}carbamate, GLYCEROL, IODIDE ION, ... 著者 Chumanevich, A.A, Wang, Y.-F, Kovalevsky, A.Y, Weber, I.T. 登録日 2009-07-07 公開日 2009-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 Design, Synthesis, Protein-Ligand X-ray Structure, and Biological Evaluation of a Series of Novel Macrocyclic Human Immunodeficiency Virus-1 Protease Inhibitors to Combat Drug Resistance. J.Med.Chem., 52, 2009
5AZP	Crystal structure of a membrane protein from Pseudomonas aeruginosa 分子名称: (2S)-1-(pentanoyloxy)propan-2-yl hexanoate, ACETATE ION, FORMIC ACID, ... 著者 Yonehara, R, Yamashita, E, Nakagawa, A. 登録日 2015-10-21 公開日 2016-06-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Crystal structures of OprN and OprJ, outer membrane factors of multidrug tripartite efflux pumps of Pseudomonas aeruginosa. Proteins, 84, 2016
3V7K	Co-crystal structure of K72E variant of rat polymerase beta: Enzyme-DNA binary complex 分子名称: DNA (5'-D(P*AP*TP*GP*TP*GP*AP*GP*T)-3'), DNA (5'-D(P*CP*AP*AP*AP*CP*TP*CP*AP*CP*AP*A)-3'), DNA polymerase beta, ... 著者 Rangarajan, S, Jaeger, J. 登録日 2011-12-21 公開日 2013-01-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.271 Å) 主引用文献 Crystallographic studies of K72E mutant DNA polymerase explain loss of lyase function and reveal changes in the overall conformational state of the polymerase domain To be Published
7W8N	Microbial Hormone-sensitive lipase E53 wild type 分子名称: (4-nitrophenyl) hexanoate, 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, ... 著者 Yang, X, Li, Z, Xu, X, Li, J. 登録日 2021-12-08 公開日 2022-02-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Mechanism and Structural Insights Into a Novel Esterase, E53, Isolated From Erythrobacter longus . Front Microbiol, 12, 2021
5BPL	Crystal structure of ADP and Pi bound human Hsp70 NBD mutant R272K. 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Narayanan, D, Engh, R.A. 登録日 2015-05-28 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Nucleotide binding to variants of the HSP70-NBD. To Be Published
7W4A	Cryo-EM structure of the gastric proton pump complexed with revaprazan 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... 著者 Abe, K, Tanaka, S, Morita, M, Yamagishi, T. 登録日 2021-11-26 公開日 2022-03-02 最終更新日 2022-07-20 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump. J.Med.Chem., 65, 2022
5AXC	Crystal structure of mouse SAHH complexed with 3'-keto aristeromycin 分子名称: (2S,3R,5R)-3-(6-amino-9H-purin-9-yl)-2-hydroxy-5-(hydroxymethyl)cyclopentanone, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Kusakabe, Y, Ishihara, M, Tanaka, N. 登録日 2015-07-24 公開日 2016-07-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of mouse SAHH complexed with 3'-keto aristeromycin To Be Published

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