7X3K
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7Z38
| Structure of the RAF1-HSP90-CDC37 complex (RHC-I) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... | 著者 | Mesa, P, Garcia-Alonso, S, Barbacid, M, Montoya, G. | 登録日 | 2022-03-01 | 公開日 | 2022-09-14 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation. Mol.Cell, 82, 2022
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7Z37
| Structure of the RAF1-HSP90-CDC37 complex (RHC-II) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... | 著者 | Mesa, P, Garcia-Alonso, S, Barbacid, M, Montoya, G. | 登録日 | 2022-03-01 | 公開日 | 2022-09-14 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | 主引用文献 | Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation. Mol.Cell, 82, 2022
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7X42
| Cryo-EM structure of Coxsackievirus B1 pre-A-particle in complex with nAb 8A10 (classified from CVB1 mature virion in complex with 8A10 and 2E6) | 分子名称: | 8A10 heavy chain, 8A10 light chain, Capsid protein VP0, ... | 著者 | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | 登録日 | 2022-03-01 | 公開日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.88 Å) | 主引用文献 | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7X40
| Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 8A10 (classified from CVB1 mature virion in complex with 8A10 and 2E6) | 分子名称: | 8A10 heavy chain, 8A10 light chain, Capsid protein VP4, ... | 著者 | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | 登録日 | 2022-03-01 | 公開日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7U4T
| Human V-ATPase in state 2 with SidK and mEAK-7 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, MTOR-associated protein MEAK7, ... | 著者 | Wang, L, Fu, T.M. | 登録日 | 2022-03-01 | 公開日 | 2022-08-24 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Identification of mEAK-7 as a human V-ATPase regulator via cryo-EM data mining. Proc.Natl.Acad.Sci.USA, 119, 2022
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7Z2P
| Tubulin-nocodazole complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Prota, A.E, Muehlethaler, T, Cavalli, A, Steinmetz, M.O. | 登録日 | 2022-02-28 | 公開日 | 2022-08-31 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Novel fragment-derived colchicine-site binders as microtubule-destabilizing agents. Eur.J.Med.Chem., 241, 2022
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7Z2N
| Tubulin-18-complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Muehlethaler, T, Prota, A.E, Cavalli, A, Steinmetz, M.O. | 登録日 | 2022-02-28 | 公開日 | 2022-08-31 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Novel fragment-derived colchicine-site binders as microtubule-destabilizing agents. Eur.J.Med.Chem., 241, 2022
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7Z2R
| Differences between the GluD1 and GluD2 receptors revealed by GluD1 X-ray crystallography, binding studies and molecular dynamics | 分子名称: | Glutamate receptor ionotropic, delta-1, SULFATE ION | 著者 | Masternak, M, Laulumaa, S, Kastrup, J.S. | 登録日 | 2022-02-28 | 公開日 | 2023-01-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.574 Å) | 主引用文献 | Differences between the GluD1 and GluD2 receptors revealed by GluD1 X-ray crystallography, binding studies and molecular dynamics. Febs J., 290, 2023
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7U4G
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7U4S
| Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from Candida albicans | 分子名称: | GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase | 著者 | Miranda, R.R, Silva, M, Iulek, J. | 登録日 | 2022-02-28 | 公開日 | 2022-04-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Expression, purification, crystallization and structure of Glyceraldehyde-3-Phosphate Dehydrogenase from Candida albicans, main causative agent of candidiasis Chem. Data Coll., 39, 2022
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7X38
| Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 8A10 (CVB1-E:8A10) | 分子名称: | 8A10 heavy chain, 8A10 light chain, VP2, ... | 著者 | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | 登録日 | 2022-02-28 | 公開日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7X3F
| Cryo-EM structure of Coxsackievirus B1 A-particle in complex with nAb 9A3 (CVB1-A:9A3) | 分子名称: | 9A3 heavy chain, 9A3 light chain, VP2, ... | 著者 | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | 登録日 | 2022-02-28 | 公開日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7X37
| Cryo-EM structure of Coxsackievirus B1 A particle in complex with nAb 2E6 (CVB1-A:2E6) | 分子名称: | 2E6 heavy chain, 2E6 light chain, VP2, ... | 著者 | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | 登録日 | 2022-02-28 | 公開日 | 2022-09-28 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7X3E
| Cryo-EM structure of Coxsackievirus B1 pre-A-particle in complex with nAb 9A3 (CVB1-pre-A:9A3) | 分子名称: | 9A3 heavy chain, 9A3 light chain, Capsid protein VP4, ... | 著者 | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | 登録日 | 2022-02-28 | 公開日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7X3D
| Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 9A3 (CVB1-M:9A3) | 分子名称: | 9A3 heavy chain, 9A3 light chain, Capsid protein VP4, ... | 著者 | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | 登録日 | 2022-02-28 | 公開日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7X3C
| Cryo-EM structure of Coxsackievirus B1 muture virion in complex with nAbs 8A10 and 5F5 (CVB1-M:8A10:5F5) | 分子名称: | 5F5 heavy chain, 5F5 light chain, 8A10 heavy chain, ... | 著者 | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | 登録日 | 2022-02-28 | 公開日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7U4E
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7U4F
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7Z2I
| TRYPSIN (BOVINE) COMPLEXED WITH compound 4 | 分子名称: | 5-[[3-(trifluoromethyl)phenyl]methyl]-1,4,6,7-tetrahydroimidazo[4,5-c]pyridine, CALCIUM ION, DIMETHYL SULFOXIDE, ... | 著者 | Schiering, N, Dalvit, C, Vulpetti, A. | 登録日 | 2022-02-27 | 公開日 | 2022-05-25 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Efficient Screening of Target-Specific Selected Compounds in Mixtures by 19 F NMR Binding Assay with Predicted 19 F NMR Chemical Shifts. Chemmedchem, 17, 2022
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7Z2H
| Cryo-EM structure of NNRTI resistant M184I/E138K mutant HIV-1 reverse transcriptase with a DNA aptamer in complex with doravirine | 分子名称: | 3-chloro-5-({1-[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl}oxy)benzonitrile, DNA (38-MER), Reverse transcriptase/ribonuclease H, ... | 著者 | Singh, A.K, Das, K. | 登録日 | 2022-02-27 | 公開日 | 2022-07-20 | 最終更新日 | 2022-10-12 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine. Proc.Natl.Acad.Sci.USA, 119, 2022
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7Z2D
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7Z2A
| P. berghei kinesin-8B motor domain in no nucleotide state bound to tubulin dimer | 分子名称: | Detyrosinated tubulin alpha-1B chain, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-8, ... | 著者 | Liu, T, Shilliday, F, Cook, A.D, Moores, C.A. | 登録日 | 2022-02-26 | 公開日 | 2022-10-19 | 最終更新日 | 2022-11-30 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Mechanochemical tuning of a kinesin motor essential for malaria parasite transmission. Nat Commun, 13, 2022
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7Z29
| Cryo-EM structure of NNRTI resistant M184I/E138K mutant HIV-1 reverse transcriptase with a DNA aptamer in complex with nevirapine | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, DNA (38-MER), Reverse transcriptase/ribonuclease H, ... | 著者 | Singh, A.K, Das, K. | 登録日 | 2022-02-26 | 公開日 | 2022-07-20 | 最終更新日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine. Proc.Natl.Acad.Sci.USA, 119, 2022
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7Z2E
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