7U4E

Neuraminidase from influenza virus A/Bilthoven/17938/1969(H3N2)

Summary for 7U4E

• Entry DOI: 10.2210/pdb7u4e/pdb
• Descriptor: Neuraminidase, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (6 entities in total)
• Functional Keywords: neuraminidase, influenza, viral protein, hydrolase
• Biological source: Influenza A virus (A/Bilthoven/17938/1969(H3N2))
• Total number of polymer chains: 4
• Total formula weight: 215501.47

Authors

Lei, R.,Hernandez Garcia, A. (deposition date: 2022-02-28, release date: 2022-10-19, Last modification date: 2023-10-18)

• Primary citation: Lei, R.,Tan, T.J.C.,Hernandez Garcia, A.,Wang, Y.,Diefenbacher, M.,Teo, C.,Gopan, G.,Tavakoli Dargani, Z.,Teo, Q.W.,Graham, C.S.,Brooke, C.B.,Nair, S.K.,Wu, N.C.; Prevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase.; Nat Commun, 13:6443-6443, 2022; PubMed: 36307418; DOI: 10.1038/s41467-022-34060-8

Experimental method

X-RAY DIFFRACTION (1.54 Å)