7Z2P

Tubulin-nocodazole complex

Summary for 7Z2P

• Entry DOI: 10.2210/pdb7z2p/pdb
• Descriptor: Tubulin alpha-1B chain, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Tubulin beta-2B chain, ... (11 entities in total)
• Functional Keywords: tubulin fold, cytoskeleton, microtubule, cell cycle
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 6
• Total formula weight: 265183.93

Authors

Prota, A.E.,Muehlethaler, T.,Cavalli, A.,Steinmetz, M.O. (deposition date: 2022-02-28, release date: 2022-08-31, Last modification date: 2024-01-31)

• Primary citation: de la Roche, N.M.,Muhlethaler, T.,Di Martino, R.M.C.,Ortega, J.A.,Gioia, D.,Roy, B.,Prota, A.E.,Steinmetz, M.O.,Cavalli, A.; Novel fragment-derived colchicine-site binders as microtubule-destabilizing agents.; Eur.J.Med.Chem., 241:114614-114614, 2022; PubMed: 35939994; DOI: 10.1016/j.ejmech.2022.114614

Experimental method

X-RAY DIFFRACTION (2 Å)