7X40

Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 8A10 (classified from CVB1 mature virion in complex with 8A10 and 2E6)

Summary for 7X40

• Entry DOI: 10.2210/pdb7x40/pdb
• EMDB information: 32998
• Descriptor: 8A10 light chain, 8A10 heavy chain, Virion protein 1, ... (7 entities in total)
• Functional Keywords: coxsackievirus b1, neutralizing antibody, cryo-em, virus
• Biological source: Mus musculus; More
• Total number of polymer chains: 6
• Total formula weight: 119668.32

Authors

Zheng, Q.,Zhu, R.,Sun, H.,Cheng, T.,Li, S.,Xia, N. (deposition date: 2022-03-01, release date: 2022-09-28)

• Primary citation: Zheng, Q.,Zhu, R.,Yin, Z.,Xu, L.,Sun, H.,Yu, H.,Wu, Y.,Jiang, Y.,Huang, Q.,Huang, Y.,Zhang, D.,Liu, L.,Yang, H.,He, M.,Zhou, Z.,Jiang, Y.,Chen, Z.,Zhao, H.,Que, Y.,Kong, Z.,Zhou, L.,Li, T.,Zhang, J.,Luo, W.,Gu, Y.,Cheng, T.,Li, S.,Xia, N.; Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.; Cell Host Microbe, 30:1279-1294.e6, 2022; PubMed: 36002016; DOI: 10.1016/j.chom.2022.08.001

Experimental method

ELECTRON MICROSCOPY (3.02 Å)