7AQY
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7AR0
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7AQZ
| Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB14) | 分子名称: | CITRIC ACID, Nanobody VSG2(NB14), SODIUM ION, ... | 著者 | Stebbins, C.E, Hempelmann, A, VanStraaten, M. | 登録日 | 2020-10-23 | 公開日 | 2021-11-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome. Cell Rep, 37, 2021
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6L5G
| Crystal structure of yak lactoperoxidase with disordered heme moiety at 2.50 A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Singh, P.K, Rani, C, Sharma, P, Sharma, S, Singh, T.P. | 登録日 | 2019-10-23 | 公開日 | 2019-11-06 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Potassium-induced partial inhibition of lactoperoxidase: structure of the complex of lactoperoxidase with potassium ion at 2.20 angstrom resolution. J.Biol.Inorg.Chem., 26, 2021
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2A7C
| On the Routine Use of Soft X-Rays in Macromolecular Crystallography, Part III- The Optimal Data Collection Wavelength | 分子名称: | Elastase 1, GLYCEROL, SULFATE ION, ... | 著者 | Mueller-Dieckmann, C, Panjikar, S, Tucker, P.A, Weiss, M.S. | 登録日 | 2005-07-05 | 公開日 | 2005-07-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | On the routine use of soft X-rays in macromolecular crystallography. Part III. The optimal data-collection wavelength. Acta Crystallogr.,Sect.D, 61, 2005
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4NGA
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6M7E
| Structure of bovine lactoperoxidase with multiple iodide ions in the distaline heme cavity. | 分子名称: | 1-(OXIDOSULFANYL)METHANAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Maurya, A, Viswanathan, V, Pandey, N, Singh, A.K, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2020-03-18 | 公開日 | 2020-04-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Structure of bovine lactoperoxidase with multiple iodide ions in the distaline heme cavity. To Be Published
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6GJD
| Erk2 signalling protein | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, Mitogen-activated protein kinase 1, ... | 著者 | O'Reilly, M. | 登録日 | 2018-05-16 | 公開日 | 2019-01-02 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Quantitation of ERK1/2 inhibitor cellular target occupancies with a reversible slow off-rate probe. Chem Sci, 9, 2018
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3JUU
| Crystal structure of porphyranase B (PorB) from Zobellia galactanivorans | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, SULFATE ION, ... | 著者 | Hehemann, J.H, Correc, G, Barbeyron, T, Michel, G, Czjzek, M. | 登録日 | 2009-09-15 | 公開日 | 2010-04-07 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Transfer of carbohydrate-active enzymes from marine bacteria to Japanese gut microbiota. Nature, 464, 2010
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1YS6
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7N3V
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2H5X
| RuvA from Mycobacterium tuberculosis | 分子名称: | GLYCEROL, Holliday junction ATP-dependent DNA helicase ruvA | 著者 | Prabu, J.R, Thamotharan, S, Khanduja, J.S, Alipio, E.Z, Kim, C.Y, Waldo, G.S, Terwilliger, T.C, Segelke, B, Lekin, T, Toppani, D, Hung, L.W, Yu, M, Bursey, E, Muniyappa, K, Chandra, N.R, Vijayan, M. | 登録日 | 2006-05-28 | 公開日 | 2006-08-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis RuvA, a protein involved in recombination. ACTA CRYSTALLOGR.,SECT.F, 62, 2006
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2C6D
| Aurora A kinase activated mutant (T287D) in complex with ADPNP | 分子名称: | GLYCEROL, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Pauptit, R.A, Pannifer, A.D, Breed, J, McMiken, H.H.J, Rowsell, S, Anderson, M. | 登録日 | 2005-11-09 | 公開日 | 2006-01-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Sar and Inhibitor Complex Structure Determination of a Novel Class of Potent and Specific Aurora Kinase Inhibitors. Bioorg.Med.Chem.Lett., 16, 2006
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2GK4
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7NT9
| Trimeric SARS-CoV-2 spike ectodomain in complex with biliverdin (closed conformation) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | 著者 | Rosa, A, Pye, V.E, Nans, A, Cherepanov, P. | 登録日 | 2021-03-09 | 公開日 | 2021-04-28 | 最終更新日 | 2021-06-09 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity. Sci Adv, 7, 2021
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7NTA
| Trimeric SARS-CoV-2 spike ectodomain in complex with biliverdin (one RBD erect) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | 著者 | Rosa, A, Pye, V.E, Nans, A, Cherepanov, P. | 登録日 | 2021-03-09 | 公開日 | 2021-04-28 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity. Sci Adv, 7, 2021
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7NTC
| Trimeric SARS-CoV-2 spike ectodomain bound to P008_056 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | 著者 | Rosa, A, Pye, V.E, Nans, A, Cherepanov, P. | 登録日 | 2021-03-09 | 公開日 | 2021-04-28 | 最終更新日 | 2021-06-09 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity. Sci Adv, 7, 2021
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7SG6
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8R7G
| Crystal structure of the kinase domain of ACVR1 (ALK2) with M4K2234 | 分子名称: | 2-fluoranyl-6-methoxy-4-[4-methyl-5-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pyridin-3-yl]benzamide, Activin receptor type I | 著者 | Williams, E.P, Cros, J, Ensan, D, Smil, D, Edwards, A.M, O'Meara, J.A, Fernandez-Cid, A, Isaac, M.B, Al-awar, R, Bullock, A.N. | 登録日 | 2023-11-24 | 公開日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma. J.Med.Chem., 63, 2020
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2RHK
| Crystal structure of influenza A NS1A protein in complex with F2F3 fragment of human cellular factor CPSF30, Northeast Structural Genomics Targets OR8C and HR6309A | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cleavage and polyadenylation specificity factor subunit 4, NITRATE ION, ... | 著者 | Das, K, Ma, L.-C, Xiao, R, Radvansky, B, Aramini, J, Zhao, L, Arnold, E, Krug, R.M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-10-09 | 公開日 | 2008-07-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural basis for suppression of a host antiviral response by influenza A virus. Proc.Natl.Acad.Sci.Usa, 105, 2008
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4X6X
| Human soluble epoxide hydrolase in complex with a three substituted cyclopropane derivative | 分子名称: | 3-{4-[(1-{[(1s,2R,3S)-2,3-diphenylcyclopropyl]carbamoyl}piperidin-4-yl)oxy]phenyl}propanoic acid, Bifunctional epoxide hydrolase 2 | 著者 | Chiyo, N, Takai, K, Ishii, T. | 登録日 | 2014-12-09 | 公開日 | 2015-04-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Three-dimensional rational approach to the discovery of potent substituted cyclopropyl urea soluble epoxide hydrolase inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
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3IDX
| Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C222 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fab b13 heavy chain, ... | 著者 | Chen, L, Kwon, Y.D, Zhou, T, Wu, X, O'Dell, S, Cavacini, L, Hessell, A.J, Pancera, M, Tang, M, Xu, L, Yang, Z.Y, Zhang, M.Y, Arthos, J, Burton, D.R, Dimitrov, D.S, Nabel, G.J, Posner, M, Sodroski, J, Wyatt, R, Mascola, J.R, Kwong, P.D. | 登録日 | 2009-07-22 | 公開日 | 2009-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120. Science, 326, 2009
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4LY9
| Human GKRP complexed to AMG-1694 [(2R)-1,1,1-trifluoro-2-{4-[(2S)-2-{[(3S)-3-methylmorpholin-4-yl]methyl}-4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol] and sorbitol-6-phosphate | 分子名称: | (2R)-1,1,1-trifluoro-2-{4-[(2S)-2-{[(3S)-3-methylmorpholin-4-yl]methyl}-4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... | 著者 | Jordan, S.R. | 登録日 | 2013-07-30 | 公開日 | 2013-11-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors. Nature, 504, 2013
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2VE7
| Crystal structure of a bonsai version of the human Ndc80 complex | 分子名称: | GLYCEROL, KINETOCHORE PROTEIN HEC1, KINETOCHORE PROTEIN SPC25, ... | 著者 | Ciferri, C, Pasqualato, S, Dos Reis, G, Screpanti, E, Maiolica, A, Polka, J, De Luca, J.G, De Wulf, P, Salek, M, Rappsilber, J, Moores, C.A, Salmon, E.D, Musacchio, A. | 登録日 | 2007-10-17 | 公開日 | 2008-05-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex Cell(Cambridge,Mass.), 133, 2008
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1ZG7
| Crystal Structure of 2-(5-{[amino(imino)methyl]amino}-2-chlorophenyl)-3-sulfanylpropanoic acid Bound to Activated Porcine Pancreatic Carboxypeptidase B | 分子名称: | 2-(5-{[AMINO(IMINO)METHYL]AMINO}-2-CHLOROPHENYL)-3-SULFANYLPROPANOIC ACID, ZINC ION, procarboxypeptidase B | 著者 | Adler, M, Bryant, J, Buckman, B, Islam, I, Larsen, B, Finster, S, Kent, L, May, K, Mohan, R, Yuan, S, Whitlow, M. | 登録日 | 2005-04-20 | 公開日 | 2005-07-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b. Biochemistry, 44, 2005
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