6GJD

Erk2 signalling protein

Summary for 6GJD

Entry DOI	10.2210/pdb6gjd/pdb
Descriptor	Mitogen-activated protein kinase 1, SULFATE ION, DIMETHYL SULFOXIDE, ... (6 entities in total)
Functional Keywords	erk2, inhibitor, reversible probe, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	44314.72
Authors	O'Reilly, M. (deposition date: 2018-05-16, release date: 2019-01-02)
Primary citation	Lebraud, H.,Surova, O.,Courtin, A.,O'Reilly, M.,Valenzano, C.R.,Nordlund, P.,Heightman, T.D. Quantitation of ERK1/2 inhibitor cellular target occupancies with a reversible slow off-rate probe. Chem Sci, 9:8608-8618, 2018 Cited by PubMed: 30568786 DOI: 10.1039/c8sc02754d PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.58 Å)

Structure validation