8X0Y
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![BU of 8x0y by Molmil](/molmil-images/mine/8x0y) | Crystal structure of JM-1A in complex with SARS-CoV-2 RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Heavy chain of JM-1A Fab, ... | 著者 | Mohapatra, A, Chen, X. | 登録日 | 2023-11-06 | 公開日 | 2024-06-05 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine. Plos Pathog., 20, 2024
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8X0X
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![BU of 8x0x by Molmil](/molmil-images/mine/8x0x) | Crystal structure of JE-5C in complex with SARS-CoV-2 RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of JE-5C Fab, Light chain of JE-5C Fab, ... | 著者 | Mohapatra, A, Chen, X. | 登録日 | 2023-11-06 | 公開日 | 2024-06-05 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine. Plos Pathog., 20, 2024
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8X0S
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![BU of 8x0s by Molmil](/molmil-images/mine/8x0s) | Crystal structure of r(G4C2)2 | 分子名称: | POTASSIUM ION, RNA (5'-R(*GP*GP*GP*GP*CP*CP*GP*GP*GP*GP*C)-3') | 著者 | Geng, Y, Liu, C, Cai, Q, Zhu, G. | 登録日 | 2023-11-05 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.956 Å) | 主引用文献 | Crystal structure of a tetrameric RNA G-quadruplex formed by hexanucleotide repeat expansions of C9orf72 in ALS/FTD. Nucleic Acids Res., 2024
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8WZB
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![BU of 8wzb by Molmil](/molmil-images/mine/8wzb) | RS head-neck monomer | 分子名称: | DPY30 domain containing 2, DnaJ homolog subfamily B member 13, Nucleoside diphosphate kinase homolog 5, ... | 著者 | Meng, X, Cong, Y. | 登録日 | 2023-11-01 | 公開日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia. Nat Commun, 15, 2024
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8WZ2
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![BU of 8wz2 by Molmil](/molmil-images/mine/8wz2) | Structure of 26RFa-pyroglutamylated RFamide peptide receptor complex | 分子名称: | G-alpha q, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Jin, S, Li, X, Xu, Y, Guo, S, Wu, C, Zhang, H, Yuan, Q, Xu, H.E, Xie, X, Jiang, Y. | 登録日 | 2023-11-01 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Structural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor. Cell Discov, 10, 2024
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8WYG
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![BU of 8wyg by Molmil](/molmil-images/mine/8wyg) | Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor 22 | 分子名称: | 2-[[5-[2-(4-fluoranyl-2,6-dimethyl-phenoxy)-5-(2-oxidanylpropan-2-yl)phenyl]-1-methyl-2-oxidanylidene-pyridin-4-yl]amino]-~{N}-(4-oxidanylcyclohexyl)ethanamide, Bromodomain-containing protein 2 | 著者 | Xu, H, Zhao, X, Shen, H, Xu, Y, Wu, X. | 登録日 | 2023-10-30 | 公開日 | 2024-01-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | 主引用文献 | Discovery of Novel Phenoxyaryl Pyridones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with High Selectivity for the Second Bromodomain (BD2) to Potentially Treat Acute Myeloid Leukemia. J.Med.Chem., 67, 2024
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8WY7
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![BU of 8wy7 by Molmil](/molmil-images/mine/8wy7) | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor 22 | 分子名称: | 2-[[5-[2-(4-fluoranyl-2,6-dimethyl-phenoxy)-5-(2-oxidanylpropan-2-yl)phenyl]-1-methyl-2-oxidanylidene-pyridin-4-yl]amino]-~{N}-(4-oxidanylcyclohexyl)ethanamide, Bromodomain-containing protein 4 | 著者 | Xu, H, Zhao, X, Shen, H, Xu, Y, Wu, X. | 登録日 | 2023-10-30 | 公開日 | 2024-01-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | Discovery of Novel Phenoxyaryl Pyridones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with High Selectivity for the Second Bromodomain (BD2) to Potentially Treat Acute Myeloid Leukemia. J.Med.Chem., 67, 2024
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8WY3
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![BU of 8wy3 by Molmil](/molmil-images/mine/8wy3) | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor 21 | 分子名称: | Bromodomain-containing protein 4, ~{N}-cyclopropyl-2-[[5-[2-(4-fluoranyl-2,6-dimethyl-phenoxy)-5-(2-oxidanylpropan-2-yl)phenyl]-1-methyl-2-oxidanylidene-pyridin-4-yl]amino]ethanamide | 著者 | Xu, H, Zhao, X, Shen, H, Xu, Y, Wu, X. | 登録日 | 2023-10-30 | 公開日 | 2024-01-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Discovery of Novel Phenoxyaryl Pyridones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with High Selectivity for the Second Bromodomain (BD2) to Potentially Treat Acute Myeloid Leukemia. J.Med.Chem., 67, 2024
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8WXY
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![BU of 8wxy by Molmil](/molmil-images/mine/8wxy) | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor 23 | 分子名称: | 5-[2-(4-fluoranyl-2,6-dimethyl-phenoxy)-5-(2-oxidanylpropan-2-yl)phenyl]-1-methyl-4-[(2-morpholin-4-yl-2-oxidanylidene-ethyl)amino]pyridin-2-one, Bromodomain-containing protein 4, GLYCEROL | 著者 | Xu, H, Zhao, X, Shen, H, Xu, Y, Wu, X. | 登録日 | 2023-10-30 | 公開日 | 2024-01-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | 主引用文献 | Discovery of Novel Phenoxyaryl Pyridones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with High Selectivity for the Second Bromodomain (BD2) to Potentially Treat Acute Myeloid Leukemia. J.Med.Chem., 67, 2024
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8WXX
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8WWY
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![BU of 8wwy by Molmil](/molmil-images/mine/8wwy) | Crystal structure of mouse TIFA/TIFAB heterodimer | 分子名称: | (2R,5R)-hexane-2,5-diol, TRAF-interacting protein with FHA domain-containing protein A, TRAF-interacting protein with FHA domain-containing protein B | 著者 | Nakamura, T. | 登録日 | 2023-10-27 | 公開日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | TIFAB regulates the TIFA-TRAF6 signaling pathway involved in innate immunity by forming a heterodimer complex with TIFA. Proc.Natl.Acad.Sci.USA, 121, 2024
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8WWW
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![BU of 8www by Molmil](/molmil-images/mine/8www) | Crystal structure of the adenylation domain of SyAstC | 分子名称: | Carrier domain-containing protein, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Li, Z, Zhu, Z, Zhu, D, Shen, Y. | 登録日 | 2023-10-27 | 公開日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Functional Application of the Single-Module NRPS-like d-Alanyltransferase in Maytansinol Biosynthesis Acs Catalysis, 14, 2024
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8WWS
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![BU of 8wws by Molmil](/molmil-images/mine/8wws) | Crystal structure of cis-epoxysuccinate hydrolase from Klebsiella oxytoca with L(+)-tartaric acid | 分子名称: | (S)-2-haloacid dehalogenase, 1,2-ETHANEDIOL, CARBONATE ION, ... | 著者 | Han, Y, Kong, X.D, Li, J, Xu, J.H. | 登録日 | 2023-10-26 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structural Insights of a cis -Epoxysuccinate Hydrolase Facilitate the Development of Robust Biocatalysts for the Production of l-(+)-Tartrate. Biochemistry, 63, 2024
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8WWR
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8WUX
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![BU of 8wux by Molmil](/molmil-images/mine/8wux) | Cryo-EM structure of H. thermophilus GroEL-GroES bullet complex | 分子名称: | Chaperonin GroEL, Co-chaperonin GroES, MAGNESIUM ION, ... | 著者 | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | 登録日 | 2023-10-21 | 公開日 | 2024-03-27 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural insights into thermophilic chaperonin complexes. Structure, 32, 2024
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8WUW
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![BU of 8wuw by Molmil](/molmil-images/mine/8wuw) | Cryo-EM structure of H. thermophilus GroEL-GroES2 asymmetric football complex | 分子名称: | Chaperonin GroEL, Co-chaperonin GroES, MAGNESIUM ION, ... | 著者 | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | 登録日 | 2023-10-21 | 公開日 | 2024-03-27 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural insights into thermophilic chaperonin complexes. Structure, 32, 2024
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8WUV
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![BU of 8wuv by Molmil](/molmil-images/mine/8wuv) | SpCas9-MMLV RT-pegRNA-target DNA complex (elongation 16-nt) | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (50-MER), ... | 著者 | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | 登録日 | 2023-10-21 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature, 2024
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8WUU
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![BU of 8wuu by Molmil](/molmil-images/mine/8wuu) | SpCas9-pegRNA-target DNA complex (pre-initiation) | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (34-MER), DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), ... | 著者 | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | 登録日 | 2023-10-21 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature, 2024
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8WUT
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![BU of 8wut by Molmil](/molmil-images/mine/8wut) | SpCas9-MMLV RT-pegRNA-target DNA complex (initiation) | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (51-MER), ... | 著者 | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | 登録日 | 2023-10-21 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature, 2024
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8WUS
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![BU of 8wus by Molmil](/molmil-images/mine/8wus) | SpCas9-MMLV RT-pegRNA-target DNA complex (termination) | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (40-MER), DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), ... | 著者 | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | 登録日 | 2023-10-21 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature, 2024
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8WUC
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![BU of 8wuc by Molmil](/molmil-images/mine/8wuc) | Cryo-EM structure of H. thermoluteolus GroEL-GroES2 football complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | 著者 | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | 登録日 | 2023-10-20 | 公開日 | 2024-03-27 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural insights into thermophilic chaperonin complexes. Structure, 32, 2024
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8WU7
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![BU of 8wu7 by Molmil](/molmil-images/mine/8wu7) | Structure of a cis-Geranylfarnesyl Diphosphate Synthase from Streptomyces clavuligerus | 分子名称: | Isoprenyl transferase | 著者 | Li, F.R, Wang, Q.L, Pan, X.M, Dong, L.B. | 登録日 | 2023-10-20 | 公開日 | 2024-05-08 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Discovery, Structure, and Engineering of a cis-Geranylfarnesyl Diphosphate Synthase. Angew.Chem.Int.Ed.Engl., 63, 2024
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8WU6
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![BU of 8wu6 by Molmil](/molmil-images/mine/8wu6) | Structure of a Nerylneryl Diphosphate Synthase from Solanum lycopersicum | 分子名称: | Nerylneryl diphosphate synthase CPT2, chloroplastic | 著者 | Li, F.R, Wang, Q.L, Pan, X.M, Dong, L.B. | 登録日 | 2023-10-20 | 公開日 | 2024-05-08 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Discovery, Structure, and Engineering of a cis-Geranylfarnesyl Diphosphate Synthase. Angew.Chem.Int.Ed.Engl., 63, 2024
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8WU5
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![BU of 8wu5 by Molmil](/molmil-images/mine/8wu5) | The complex of CAG repeat sequence-specific binding cPIP and dsDNA with A-A mismatch | 分子名称: | (1^2Z,4^2Z,11^2Z,14^2Z,22^2Z,25^2Z,32^2Z,35^2Z,19R,40R)-1^1,4^1,11^1,14^1,22^1,25^1,32^1,35^1-octamethyl-2,5,9,12,15,20,23,26,30,33,36,41-dodecaoxo-1^1H,4^1H,11^1H,14^1H,22^1H,25^1H,32^1H,35^1H-3,6,10,13,16,21,24,27,31,34,37,42-dodecaaza-1(2,4),11,22,32(4,2)-tetraimidazola-4,14,25,35(4,2)-tetrapyrrolacyclodotetracontaphane-19,40-diaminium, DNA (5'-D(*GP*CP*(CBR)P*GP*AP*GP*CP*AP*GP*CP*AP*CP*GP*GP*C)-3') | 著者 | Abe, K, Takeda, K, Sugiyama, H. | 登録日 | 2023-10-20 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Studies of a Complex of a CAG/CTG Repeat Sequence-Specific Binding Molecule and A-A-Mismatch-Containing DNA. Jacs Au, 4, 2024
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8WU4
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![BU of 8wu4 by Molmil](/molmil-images/mine/8wu4) | Cryo-EM structure of native H. thermoluteolus TH-1 GroEL | 分子名称: | Chaperonin GroEL | 著者 | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | 登録日 | 2023-10-20 | 公開日 | 2024-03-27 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into thermophilic chaperonin complexes. Structure, 32, 2024
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