PDB: 5470 件ウェブページステータス検索Chemie searchBIRD

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6ZHA	Cryo-EM structure of DNA-PK monomer 分子名称: DNA, DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-PKcs, X-ray repair cross-complementing protein 5, ... 著者 Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L. 登録日 2020-06-21 公開日 2020-10-21 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Dimers of DNA-PK create a stage for DNA double-strand break repair. Nat.Struct.Mol.Biol., 28, 2021
6HCJ	Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... 著者 Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. 登録日 2018-08-15 公開日 2018-10-17 最終更新日 2018-11-14 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
6HCQ	Structure of the rabbit collided di-ribosome (collided monosome) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... 著者 Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. 登録日 2018-08-16 公開日 2018-10-17 最終更新日 2018-11-14 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
6ZHE	Cryo-EM structure of DNA-PK dimer 分子名称: DNA (25-MER), DNA (26-MER), DNA (27-MER), ... 著者 Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L. 登録日 2020-06-23 公開日 2020-10-21 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (7.24 Å) 主引用文献 Dimers of DNA-PK create a stage for DNA double-strand break repair. Nat.Struct.Mol.Biol., 28, 2021
7ASV	Crystal structure of tWHD2 of Rpc5 subunit of human RNA Polymerase III 分子名称: ACETATE ION, DNA-directed RNA polymerase III subunit RPC5 著者 Vannini, A, Abascal-Palacios, G, Ramsay, E.P. 登録日 2020-10-28 公開日 2020-12-30 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structure of human RNA polymerase III. Nat Commun, 11, 2020
7DU2	RNA polymerase III EC complex in post-translocation state 分子名称: DNA (5'-D(P*GP*TP*CP*TP*GP*AP*TP*CP*TP*CP*GP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*CP*GP*AP*GP*AP*TP*CP*AP*GP*AP*CP*GP*AP*GP*AP*T)-3'), DNA-directed RNA polymerase III subunit RPC1, ... 著者 Li, L, Yu, Z, Zhao, D, Ren, Y, Hou, H, Xu, Y. 登録日 2021-01-07 公開日 2021-03-17 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.35 Å) 主引用文献 Structure of human RNA polymerase III elongation complex. Cell Res., 31, 2021
1A31	HUMAN RECONSTITUTED DNA TOPOISOMERASE I IN COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX 分子名称: DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*5IUP*5IU*TP*GP*AP*AP*AP*AP*AP*5IUP*5IUP*5IUP*5IUP*T)-3'), DNA (5'-D(*AP*AP*AP*AP*AP*TP*5IUP*5IUP*5IUP*5IUP*CP*AP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3'), PROTEIN (TOPOISOMERASE I) 著者 Redinbo, M.R, Stewart, L, Kuhn, P, Champoux, J.J, Hol, W.G.J. 登録日 1998-01-27 公開日 1998-08-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science, 279, 1998
1A49	BIS MG-ATP-K-OXALATE COMPLEX OF PYRUVATE KINASE 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, OXALATE ION, ... 著者 Larsen, T.M, Benning, M.M, Rayment, I, Reed, G.H. 登録日 1998-02-12 公開日 1999-04-20 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the bis(Mg2+)-ATP-oxalate complex of the rabbit muscle pyruvate kinase at 2.1 A resolution: ATP binding over a barrel. Biochemistry, 37, 1998
1A35	HUMAN TOPOISOMERASE I/DNA COMPLEX 分子名称: DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*AP*(BRU)P*(BRU)P*TP*TP*T)-3'), DNA (5'-D(*AP*AP*AP*AP*AP*TP*+UP*+UP*+UP*+UP*CP*+UP*AP*AP*GP*TP*CP*TP*TP*TP*+ UP*T)-3'), PROTEIN (DNA TOPOISOMERASE I) 著者 Redinbo, M.R, Stewart, L, Kuhn, P, Champoux, J.J, Hol, W.G. 登録日 1998-01-29 公開日 1998-08-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science, 279, 1998
5GT3	Crystal structure of nucleosome particle in the presence of human testis-specific histone variant, hTh2b 分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-D, ... 著者 Kumarevel, T, Sivaraman, P. 登録日 2016-08-18 公開日 2017-02-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b Biophys. Chem., 221, 2017
1A36	TOPOISOMERASE I/DNA COMPLEX 分子名称: DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*A P*TP*TP*TP*TP*T)- 3'), DNA (5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*C P*TP*TP*TP*TP*T)- 3'), TOPOISOMERASE I 著者 Stewart, L, Redinbo, M.R, Qiu, X, Champoux, J.J, Hol, W.G.J. 登録日 1998-01-29 公開日 1998-08-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A model for the mechanism of human topoisomerase I. Science, 279, 1998
1A5U	PYRUVATE KINASE COMPLEX WITH BIS MG-ATP-NA-OXALATE 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, OXALATE ION, ... 著者 Larsen, T.M, Benning, M.M, Rayment, I, Reed, G.H. 登録日 1998-02-18 公開日 1999-03-02 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure of the bis(Mg2+)-ATP-oxalate complex of the rabbit muscle pyruvate kinase at 2.1 A resolution: ATP binding over a barrel. Biochemistry, 37, 1998
1AQF	PYRUVATE KINASE FROM RABBIT MUSCLE WITH MG, K, AND L-PHOSPHOLACTATE 分子名称: L-PHOSPHOLACTATE, MAGNESIUM ION, POTASSIUM ION, ... 著者 Larsen, T.M, Benning, M.M, Wesenberg, G.E, Rayment, I, Reed, G.H. 登録日 1997-07-29 公開日 1998-09-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Ligand-induced domain movement in pyruvate kinase: structure of the enzyme from rabbit muscle with Mg2+, K+, and L-phospholactate at 2.7 A resolution. Arch.Biochem.Biophys., 345, 1997
5FQ2	Crystal structure of human SUMO E1 UFD domain in complex with Ubc9 in a P422 space group. 分子名称: SUMO-ACTIVATING ENZYME SUBUNIT 2, SUMO-CONJUGATING ENZYME UBC9 著者 Liu, B, Castano, L, Lois, M, Reverter, D. 登録日 2015-12-04 公開日 2016-11-16 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 Crystal Structure of Human Sumo E1 Ufd Domain in Complex with Ubc9. To be Published
5IFE	Crystal structure of the human SF3b core complex 分子名称: PHD finger-like domain-containing protein 5A, POTASSIUM ION, Splicing factor 3B subunit 1, ... 著者 Cretu, C, Dybkov, O, De Laurentiis, E, Will, C.L, Luhrmann, R, Pena, V. 登録日 2016-02-25 公開日 2016-10-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations. Mol.Cell, 64, 2016
2O25	Ubiquitin-Conjugating Enzyme E2-25 kDa Complexed With SUMO-1-Conjugating Enzyme UBC9 分子名称: SUMO-1-conjugating enzyme UBC9, Ubiquitin-conjugating enzyme E2-25 kDa 著者 Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2006-11-29 公開日 2007-01-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A Novel and Unexpected Complex Between the SUMO-1-Conjugating Enzyme UBC9 and the Ubiquitin-Conjugating Enzyme E2-25 kDa To be Published
5GSU	Crystal structure of nucleosome core particle consisting of human testis-specific histone variants, Th2A and Th2B 分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-A, ... 著者 Kumarevel, T, Sivaraman, P. 登録日 2016-08-17 公開日 2017-02-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b Biophys. Chem., 221, 2017
2MP2	Solution structure of SUMO dimer in complex with SIM2-3 from RNF4 分子名称: E3 ubiquitin-protein ligase RNF4, Small ubiquitin-related modifier 3 著者 Xu, Y, Plechanovov, A, Simpson, P, Marchant, J, Leidecker, O, Sebastian, K, Hay, R.T, Matthews, S.J. 登録日 2014-05-09 公開日 2014-07-02 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural insight into SUMO chain recognition and manipulation by the ubiquitin ligase RNF4. Nat Commun, 5, 2014
2PX9	The intrinsic affinity between E2 and the Cys domain of E1 in Ubiquitin-like modifications 分子名称: SUMO-activating enzyme subunit 2, SUMO-conjugating enzyme UBC9 著者 Wang, J.H, Hu, W.D, Cai, S, Lee, B, Song, J, Chen, Y. 登録日 2007-05-14 公開日 2007-07-24 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The intrinsic affinity between E2 and the Cys domain of E1 in ubiquitin-like modifications. Mol.Cell, 27, 2007
2LYV	Solution structure of the two RRM domains of hnRNP A1 (UP1) using segmental isotope labeling 分子名称: Heterogeneous nuclear ribonucleoprotein A1 著者 Barraud, P, Allain, F.H.-T. 登録日 2012-09-19 公開日 2012-12-26 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structure of the two RNA recognition motifs of hnRNP A1 using segmental isotope labeling: how the relative orientation between RRMs influences the nucleic acid binding topology. J.Biomol.Nmr, 55, 2013
6CWY	Crystal structure of SUMO E1 in complex with an allosteric inhibitor 分子名称: GLYCEROL, MAGNESIUM ION, SULFATE ION, ... 著者 Lv, Z, Yuan, L, Atkison, J.H, Williams, K.M, Olsen, S.K. 登録日 2018-04-01 公開日 2019-01-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.462 Å) 主引用文献 Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme. Nat Commun, 9, 2018
1NH3	Human Topoisomerase I Ara-C Complex 分子名称: 5'-D(*(GNG)P*GP*AP*AP*AP*AP*AP*UP*UP*UP*UP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*UP*(UBB))-3', 5'-D(*AP*AP*AP*AP*AP*TP*UP*UP*UP*UP*CP*(CAR)P*AP*AP*GP*UP*CP*UP*UP*UP*UP*T)-3', ... 著者 Chrencik, J.E, Burgin, A.B, Pommier, Y, Stewart, L, Redinbo, M.R. 登録日 2002-12-18 公開日 2003-03-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural Impact of the Leukemia Drug 1-beta-D-Arabinofuranosylcytosine (Ara-C) on the Covalent Human Topoisomerase I-DNA Complex J.Biol.Chem., 278, 2003
1LPQ	Human DNA Topoisomerase I (70 Kda) In Non-Covalent Complex With A 22 Base Pair DNA Duplex Containing an 8-oxoG Lesion 分子名称: 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*(8OG)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*CP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3', DNA topoisomerase I 著者 Lesher, D.T, Pommier, Y, Stewart, L, Redinbo, M.R. 登録日 2002-05-08 公開日 2002-08-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 8-Oxoguanine rearranges the active site of human topoisomerase I Proc.Natl.Acad.Sci.USA, 99, 2002
6DCL	Crystal structure of UP1 bound to pri-miRNA-18a terminal loop 分子名称: 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3') 著者 Kooshapur, H, Sattler, M. 登録日 2018-05-07 公開日 2018-06-27 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.497 Å) 主引用文献 Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1. Nat Commun, 9, 2018
6CWZ	Crystal structure of apo SUMO E1 分子名称: SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ZINC ION 著者 Lv, Z, Yuan, L, Atkison, J.H, Williams, K.M, Olsen, S.K. 登録日 2018-04-01 公開日 2019-01-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme. Nat Commun, 9, 2018

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