7ML8
| The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ001023038 | 分子名称: | 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-2-phenyl-1,6-dihydropyrimidine-4-carboxamide, GLUTAMIC ACID, Hexa Vinylpyrrolidone K15, ... | 著者 | Cuypers, M.G, Slavish, P.J, Yun, M.K, Dubois, R, Rankovic, Z, White, S.W. | 登録日 | 2021-04-27 | 公開日 | 2021-10-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with St Jude compound AC067-19 To Be Published
|
|
7OCH
| Apo-structure of Lassa virus L protein (well-resolved polymerase core) [APO-CORE] | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-04-26 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
|
|
7MKT
| Crystal structure of r(GU)11G-NMM complex | 分子名称: | N-METHYLMESOPORPHYRIN, POTASSIUM ION, RNA (5'-R(*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3') | 著者 | Bingman, C.A, Roschdi, S, Nomura, Y, Butcher, S.E. | 登録日 | 2021-04-26 | 公開日 | 2022-11-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | An atypical RNA quadruplex marks RNAs as vectors for gene silencing. Nat.Struct.Mol.Biol., 29, 2022
|
|
7MKA
| Structure of EC+EC (leading EC-focused) | 分子名称: | DNA (40-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Yang, C, Murakami, K. | 登録日 | 2021-04-22 | 公開日 | 2022-04-27 | 最終更新日 | 2023-05-17 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Mol.Cell, 82, 2022
|
|
7MK9
| |
7OA4
| Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound L-742,001 | 分子名称: | (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, FORMIC ACID, MANGANESE (II) ION, ... | 著者 | Feracci, M, Hernandez, S, Vincentelli, R, Ferron, F, Reguera, J, Canard, B, Alvarez, K. | 登録日 | 2021-04-19 | 公開日 | 2022-08-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound L-742,001 To Be Published
|
|
7O7Z
| Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (classified for pseudoknot) | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | 登録日 | 2021-04-14 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
|
|
7O81
| Rabbit 80S ribosome colliding in another ribosome stalled by the SARS-CoV-2 pseudoknot | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | 登録日 | 2021-04-14 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
|
|
7O7Y
| Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (high resolution) | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | 登録日 | 2021-04-14 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
|
|
7O80
| Rabbit 80S ribosome in complex with eRF1 and ABCE1 stalled at the STOP codon in the mutated SARS-CoV-2 slippery site | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | 登録日 | 2021-04-14 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
|
|
7O75
| Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | 登録日 | 2021-04-13 | 公開日 | 2021-06-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
|
|
7O73
| Yeast RNA polymerase II transcription pre-initiation complex with closed distorted promoter DNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | 登録日 | 2021-04-12 | 公開日 | 2021-06-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
|
|
7O72
| Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | 登録日 | 2021-04-12 | 公開日 | 2021-06-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
|
|
7ELL
| |
7ELH
| |
7ELC
| Structure of monomeric complex of MACV L bound to Z and 3'-vRNA | 分子名称: | 3'-vRNA promoter, MANGANESE (II) ION, RING finger protein Z, ... | 著者 | Xu, X, Peng, R, Peng, Q, Shi, Y. | 登録日 | 2021-04-09 | 公開日 | 2021-05-05 | 最終更新日 | 2021-07-14 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals. Nat Microbiol, 6, 2021
|
|
7ELA
| Structure of Lassa virus polymerase in complex with 3'-vRNA and Z mutant (F36A) | 分子名称: | 3-'vRNA promoter, MANGANESE (II) ION, RING finger protein Z, ... | 著者 | Xu, X, Peng, R, Peng, Q, Shi, Y. | 登録日 | 2021-04-09 | 公開日 | 2021-05-05 | 最終更新日 | 2021-07-14 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals. Nat Microbiol, 6, 2021
|
|
7EL9
| Structure of Machupo virus L polymerase in complex with Z protein and 3'-vRNA (dimeric complex) | 分子名称: | MANGANESE (II) ION, Machupo virus 3'-vRNA promoter, RING finger protein Z, ... | 著者 | Peng, R, Xu, X, Peng, Q, Shi, Y. | 登録日 | 2021-04-09 | 公開日 | 2021-05-05 | 最終更新日 | 2021-07-14 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals. Nat Microbiol, 6, 2021
|
|
7ELB
| Structure of Machupo virus L polymerase in complex with Z protein (dimeric form) | 分子名称: | MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ... | 著者 | Peng, R, Xu, X, Peng, Q, Shi, Y. | 登録日 | 2021-04-09 | 公開日 | 2021-05-05 | 最終更新日 | 2021-07-14 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals. Nat Microbiol, 6, 2021
|
|
7O4J
| Yeast RNA polymerase II transcription pre-initiation complex (consensus) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | 登録日 | 2021-04-06 | 公開日 | 2021-06-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
|
|
7O4I
| Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | 登録日 | 2021-04-06 | 公開日 | 2021-06-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
|
|
7O4L
| Yeast TFIIH in the expanded state within the pre-initiation complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | 登録日 | 2021-04-06 | 公開日 | 2021-06-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
|
|
7O4K
| Yeast TFIIH in the contracted state within the pre-initiation complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | 登録日 | 2021-04-06 | 公開日 | 2021-06-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
|
|
7MEI
| Composite structure of EC+EC | 分子名称: | DNA (74-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Yang, C, Murakami, K. | 登録日 | 2021-04-06 | 公開日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Mol.Cell, 82, 2022
|
|
7EKJ
| |