PDB: 1955 件ウェブページステータス検索Chemie searchBIRD

---

7MC9	X-RAY STRUCTURE OF PEDV PAPAIN-LIKE PROTEASE 2 bound to UB-PA 分子名称: 3C-like proteinase, Ubiquitin, ZINC ION, ... 著者 Durie, I.A, Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D. 登録日 2021-04-01 公開日 2021-07-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.099 Å) 主引用文献 Structural insights into the interaction of papain-like protease 2 from the alphacoronavirus porcine epidemic diarrhea virus and ubiquitin Acta Cryst. D, 77, 2021
7MC6	Crystal structure of the SARS-CoV-2 ExoN-nsp10 complex containing Mg2+ ion 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... 著者 Moeller, N.M, Shi, K, Banerjee, S, Yin, L, Aihara, H. 登録日 2021-04-01 公開日 2021-05-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN. Proc.Natl.Acad.Sci.USA, 119, 2022
7MC5	Crystal structure of the SARS-CoV-2 ExoN-nsp10 complex 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, L(+)-TARTARIC ACID, ... 著者 Moeller, N.M, Shi, K, Banerjee, S, Yin, L, Aihara, H. 登録日 2021-04-01 公開日 2021-05-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN. Proc.Natl.Acad.Sci.USA, 119, 2022
7EIZ	Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading 分子名称: Helicase, MAGNESIUM ION, Non-structural protein 10, ... 著者 Yan, L, Yang, Y.X, Li, M.Y, Zhang, Y, Zheng, L.T, Ge, J, Huang, Y.C, Liu, Z.Y, Wang, T, Gao, S, Zhang, R, Huang, Y.Y, Guddat, L.W, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2021-04-01 公開日 2021-09-22 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY 主引用文献 Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading Cell, 184, 2021
7EGQ	Co-transcriptional capping machineries in SARS-CoV-2 RTC: Coupling of N7-methyltransferase and 3'-5' exoribonuclease with polymerase reveals mechanisms for capping and proofreading 分子名称: Helicase, MAGNESIUM ION, Non-structural protein 10, ... 著者 Yan, L.M, Yang, Y.X, Li, M.Y, Zhang, Y, Zheng, L.T, Ge, J, Huang, Y.C, Liu, Z.Y, Wang, T, Gao, S, Zhang, R, Huang, Y.Y, Guddat, L.W, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2021-03-25 公開日 2021-07-21 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.35 Å) 主引用文献 Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading. Cell, 184, 2021
7EG7	TFIID-based core PIC on SCP promoter 分子名称: DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. 登録日 2021-03-24 公開日 2021-05-05 最終更新日 2021-05-19 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7EGB	TFIID-based holo PIC on SCP promoter 分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... 著者 Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. 登録日 2021-03-24 公開日 2021-05-05 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7EGA	TFIID-based intermediate PIC on PUMA promoter 分子名称: DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. 登録日 2021-03-24 公開日 2021-05-05 最終更新日 2021-05-19 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7EG9	TFIID-based intermediate PIC on SCP promoter 分子名称: DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Qi, Y, Wang, X, Wu, Z, Li, J, Xu, Y. 登録日 2021-03-24 公開日 2021-05-05 最終更新日 2021-05-19 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7EG8	TFIID-based core PIC on PUMA promoter 分子名称: DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. 登録日 2021-03-24 公開日 2021-05-05 最終更新日 2021-05-19 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7EGC	p53-bound TFIID-based holo PIC on HDM2 promoter 分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... 著者 Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. 登録日 2021-03-24 公開日 2021-05-12 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7EEI	Structure of Rift Valley fever virus RNA-dependent RNA polymerase 分子名称: Replicase 著者 Wang, X, Hu, C.X. 登録日 2021-03-18 公開日 2021-11-17 最終更新日 2022-03-16 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of Rift Valley Fever Virus RNA-Dependent RNA Polymerase. J.Virol., 96, 2022
7EDX	p53-bound TFIID-based core PIC on HDM2 promoter 分子名称: DNA (84-mer), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. 登録日 2021-03-17 公開日 2021-05-05 最終更新日 2021-05-19 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7NVT	RNA polymerase II core pre-initiation complex with closed promoter DNA in distal position 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Aibara, S, Schilbach, S, Cramer, P. 登録日 2021-03-16 公開日 2021-05-05 最終更新日 2021-06-16 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
7NW0	RNA polymerase II pre-initiation complex with open promoter DNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CDK-activating kinase assembly factor MAT1, ... 著者 Aibara, S, Schilbach, S, Cramer, P. 登録日 2021-03-16 公開日 2021-05-05 最終更新日 2021-06-16 実験手法 ELECTRON MICROSCOPY (6.6 Å) 主引用文献 Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
7NVZ	RNA polymerase II pre-initiation complex with closed promoter DNA in distal position 分子名称: CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Aibara, S, Schilbach, S, Cramer, P. 登録日 2021-03-16 公開日 2021-05-05 最終更新日 2021-06-16 実験手法 ELECTRON MICROSCOPY (7.2 Å) 主引用文献 Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
7NVS	RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Aibara, S, Schilbach, S, Cramer, P. 登録日 2021-03-16 公開日 2021-05-05 最終更新日 2021-06-16 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
7NVY	RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position 分子名称: CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Aibara, S, Schilbach, S, Cramer, P. 登録日 2021-03-16 公開日 2021-05-05 最終更新日 2021-06-16 実験手法 ELECTRON MICROSCOPY (7.3 Å) 主引用文献 Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
7NVU	RNA polymerase II core pre-initiation complex with open promoter DNA 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Aibara, S, Schilbach, S, Cramer, P. 登録日 2021-03-16 公開日 2021-05-05 最終更新日 2021-06-16 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
7M1V	Structure of Zika virus NS2b-NS3 protease mutant binding the compound NSC86314 in the super-open conformation 分子名称: 1,2-ETHANEDIOL, 4-(2-{2,4-diamino-5-[2-(4-{[(2E)-1,3-thiazolidin-2-ylidene]sulfamoyl}phenyl)hydrazinyl]phenyl}hydrazinyl)-N-[(2S)-1,3-thiazolidin-2-yl]benzene-1-sulfonamide, CHLORIDE ION, ... 著者 Aleshin, A.E, Shiryaev, S.A, Liddington, R.C. 登録日 2021-03-15 公開日 2021-04-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 To be provided To Be Published
7ED5	A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase 分子名称: MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ... 著者 Shannon, A, Fattorini, V, Sama, B, Selisko, B, Feracci, M, Falcou, C, Gauffre, P, El Kazzi, P, Delpal, A, Decroly, E, Alvarez, K, Eydoux, C, Guillemot, J.-C, Moussa, A, Good, S, Colla, P, Lin, K, Sommadossi, J.-P, Zhu, Y.X, Yan, X.D, Shi, H, Ferron, F, Canard, B. 登録日 2021-03-15 公開日 2022-02-16 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase. Nat Commun, 13, 2022
7NVR	Human Mediator with RNA Polymerase II Pre-initiation complex 分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... 著者 Rengachari, S, Schilbach, S, Aibara, S, Cramer, P. 登録日 2021-03-15 公開日 2021-05-05 最終更新日 2021-06-16 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
7NUG	Influenza A/California/07/2009(H1N1) endonuclease in complex with orientin 分子名称: 1,2-ETHANEDIOL, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, DI(HYDROXYETHYL)ETHER, ... 著者 Radilova, K, Brynda, J. 登録日 2021-03-12 公開日 2021-07-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors. Int J Mol Sci, 22, 2021
7NUH	Influenza A/California/07/2009(H1N1) endonuclease with I38T mutation in complex with orientin 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Radilova, K, Brynda, J. 登録日 2021-03-12 公開日 2021-07-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors. Int J Mol Sci, 22, 2021
7M0N	The crystal structure of wild type PA endonuclease (A/Vietnam/1203/2004) in complex with Raltegravir 分子名称: GLYCEROL, MANGANESE (II) ION, N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(1-methyl-1-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}ethyl)-6-oxo-1,6-di hydropyrimidine-4-carboxamide, ... 著者 Cuypers, M.G, Slavish, P.J, Yun, M.K, Dubois, R, Rankovic, Z, White, S.W. 登録日 2021-03-11 公開日 2022-03-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. Eur.J.Med.Chem., 247, 2023

<11121314151617181920212223242526>