7OCH

Apo-structure of Lassa virus L protein (well-resolved polymerase core) [APO-CORE]

Summary for 7OCH

Entry DOI	10.2210/pdb7och/pdb
EMDB information	12807
Descriptor	RNA-directed RNA polymerase L, ZINC ION, MAGNESIUM ION (3 entities in total)
Functional Keywords	lassa virus rna-dependent rna polymerase viral rna, viral protein
Biological source	Lassa mammarenavirus
Total number of polymer chains	1
Total formula weight	253746.65
Authors	Kouba, T.,Vogel, D.,Thorkelsson, S.,Quemin, E.,Williams, H.M.,Milewski, M.,Busch, C.,Gunther, S.,Grunewald, K.,Rosenthal, M.,Cusack, S. (deposition date: 2021-04-26, release date: 2021-12-01, Last modification date: 2024-05-01)
Primary citation	Kouba, T.,Vogel, D.,Thorkelsson, S.R.,Quemin, E.R.J.,Williams, H.M.,Milewski, M.,Busch, C.,Gunther, S.,Grunewald, K.,Rosenthal, M.,Cusack, S. Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12:7018-7018, 2021 Cited by PubMed: 34857749 DOI: 10.1038/s41467-021-27305-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.14 Å)

Structure validation