PDB: 1466 件ウェブページステータス検索Chemie searchBIRD

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7O81	Rabbit 80S ribosome colliding in another ribosome stalled by the SARS-CoV-2 pseudoknot 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. 登録日 2021-04-14 公開日 2021-06-02 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
7O7Y	Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (high resolution) 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. 登録日 2021-04-14 公開日 2021-06-02 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
7MEX	Structure of yeast Ubr1 in complex with Ubc2 and N-degron 分子名称: E3 ubiquitin-protein ligase UBR1, N-degron, Ubiquitin, ... 著者 Pan, M, Zheng, Q, Wang, T, Liang, L, Yu, Y, Liu, L, Zhao, M. 登録日 2021-04-08 公開日 2021-11-24 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.35 Å) 主引用文献 Structural insights into Ubr1-mediated N-degron polyubiquitination. Nature, 600, 2021
7MEY	Structure of yeast Ubr1 in complex with Ubc2 and monoubiquitinated N-degron 分子名称: 2-(ethylamino)ethane-1-thiol, E3 ubiquitin-protein ligase UBR1, Monoubiquitinated N-degron, ... 著者 Pan, M, Zheng, Q, Wang, T, Liang, L, Yu, Y, Liu, L, Zhao, M. 登録日 2021-04-08 公開日 2021-11-24 最終更新日 2021-12-22 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Structural insights into Ubr1-mediated N-degron polyubiquitination. Nature, 600, 2021
7MDZ	80S rabbit ribosome stalled with benzamide-CHX 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S21, ... 著者 Koga, Y, Hoang, E.M, Park, Y, Keszei, A.F.A, Murray, J, Shao, S, Liau, B.B. 登録日 2021-04-06 公開日 2021-09-01 最終更新日 2021-09-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation. J.Am.Chem.Soc., 143, 2021
7MC9	X-RAY STRUCTURE OF PEDV PAPAIN-LIKE PROTEASE 2 bound to UB-PA 分子名称: 3C-like proteinase, Ubiquitin, ZINC ION, ... 著者 Durie, I.A, Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D. 登録日 2021-04-01 公開日 2021-07-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.099 Å) 主引用文献 Structural insights into the interaction of papain-like protease 2 from the alphacoronavirus porcine epidemic diarrhea virus and ubiquitin Acta Cryst. D, 77, 2021
7O2W	Structure of the C9orf72-SMCR8 complex 分子名称: Guanine nucleotide exchange protein SMCR8,Guanine nucleotide exchange protein SMCR8,Maltose/maltodextrin-binding periplasmic protein, Ubiquitin-like protein SMT3,Guanine nucleotide exchange C9orf72 著者 Noerpel, J, Cavadini, S, Schenk, A.D, Graff-Meyer, A, Chao, J, Bhaskar, V. 登録日 2021-03-31 公開日 2021-07-21 最終更新日 2022-02-02 実験手法 ELECTRON MICROSCOPY 主引用文献 Structure of the human C9orf72-SMCR8 complex reveals a multivalent protein interaction architecture. Plos Biol., 19, 2021
7M6T	Crystal structure of SOCS2/ElonginB/ElonginC bound to a non-canonical peptide that enhances phospho-peptide binding 分子名称: Elongin-B, Elongin-C, Non-canonical peptide F3, ... 著者 Kershaw, N.J, Li, K, Linossi, E.M, Nicholson, S.E. 登録日 2021-03-26 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.194 Å) 主引用文献 Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands. Nat Commun, 12, 2021
7M4N	Crystal structure of RBR E3 ligase RNF216 in complex with K63-linked di-ubiquitin 分子名称: E3 ubiquitin-protein ligase RNF216, GLYCEROL, SULFATE ION, ... 著者 Cotton, T.R, Lechtenberg, B.C. 登録日 2021-03-21 公開日 2022-01-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216. Mol.Cell, 82, 2022
7M4M	Crystal structure of RBR E3 ligase RNF216 with ubiquitin 分子名称: E3 ubiquitin-protein ligase RNF216, GLYCEROL, Ubiquitin, ... 著者 Cotton, T.R, Lechtenberg, B.C. 登録日 2021-03-21 公開日 2022-01-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216. Mol.Cell, 82, 2022
7M4O	Crystal structure of phosphorylated RBR E3 ligase RNF216 in complex with K63-linked di-ubiquitin 分子名称: 2-(2-METHOXYETHOXY)ETHANOL, E3 ubiquitin-protein ligase RNF216, GLYCEROL, ... 著者 Cotton, T.R, Lechtenberg, B.C. 登録日 2021-03-21 公開日 2022-01-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216. Mol.Cell, 82, 2022
7M3Q	Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, ... 著者 Chowdhury, A, Singer, A.U, Ogunjimi, A.A, Teyra, J, Zhang, W, Sicheri, F, Sidhu, S.S. 登録日 2021-03-18 公開日 2021-04-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV) To be published
7M2K	CDC34A-Ubiquitin-2ab inhibitor complex 分子名称: 4-[(3',5'-dichloro[1,1'-biphenyl]-4-yl)methyl]-N-ethyl-1-(methoxyacetyl)piperidine-4-carboxamide, Ubiquitin, Ubiquitin-conjugating enzyme E2 R1 著者 Ceccarelli, D.F, St-Cyr, D, Tyers, M, Sicheri, F. 登録日 2021-03-16 公開日 2021-11-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme-ubiquitin complex. Sci Adv, 7, 2021
7NWI	Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S 分子名称: 18S ribosomal RNA, 28S ribosomal RNA+BlaS, 40S ribosomal protein S11, ... 著者 Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. 登録日 2021-03-16 公開日 2021-07-07 最終更新日 2023-01-11 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
7NWG	Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S. 分子名称: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... 著者 Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. 登録日 2021-03-16 公開日 2021-07-07 最終更新日 2023-01-11 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
7NWH	Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S. 分子名称: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... 著者 Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. 登録日 2021-03-16 公開日 2021-07-07 最終更新日 2023-01-11 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
7EB9	The structure of the A20-binding inhibitor of NF-kB 1 in complex with tetra-ubiquitin 分子名称: TNFAIP3-interacting protein 1, tetra ubiquitin 著者 Lo, Y.C, Lin, S.C. 登録日 2021-03-09 公開日 2021-07-21 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural and Biochemical Basis for Higher-Order Assembly between A20-Binding Inhibitor of NF-kappa B 1 (ABIN1) and M1-Linked Ubiquitins. J.Mol.Biol., 433, 2021
7EAL	The structure of the A20-Binding Inhibitor of NF-kB 1 in complex with di-ubiquitin 分子名称: GLYCEROL, TNFAIP3-interacting protein 1, ubiquitin 著者 Lo, Y.C, Lin, S.C. 登録日 2021-03-07 公開日 2021-07-21 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural and Biochemical Basis for Higher-Order Assembly between A20-Binding Inhibitor of NF-kappa B 1 (ABIN1) and M1-Linked Ubiquitins. J.Mol.Biol., 433, 2021
7EAO	The structure of the A20-binding inhibitor of NF-kB 1 in complex with tri-ubiquitin 分子名称: Polyubiquitin-C, TNFAIP3-interacting protein 1 著者 Lo, Y.C, Lin, S.C. 登録日 2021-03-07 公開日 2021-07-21 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural and Biochemical Basis for Higher-Order Assembly between A20-Binding Inhibitor of NF-kappa B 1 (ABIN1) and M1-Linked Ubiquitins. J.Mol.Biol., 433, 2021
7LYC	Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A Lys13 and Lys15 in complex with BARD1 (residues 415-777) 分子名称: BRCA1-associated RING domain protein 1, DNA (146-MER), DNA (147-MER), ... 著者 Hu, Q, Botuyan, M.V, Zhao, D, Cui, D, Mer, E, Mer, G. 登録日 2021-03-06 公開日 2021-06-16 最終更新日 2021-09-01 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation. Nature, 596, 2021
7E8I	Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin 分子名称: BRCA1-associated RING domain protein 1, DNA (145-MER), Histone H2A, ... 著者 Dai, Y, Dai, L, Zhou, Z. 登録日 2021-03-01 公開日 2021-06-30 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin. Mol.Cell, 81, 2021
7NPO	Branched K48-K63-Ub3 分子名称: GLYCEROL, Polyubiquitin-B 著者 Lange, S.M, Kwasna, D, Kulathu, Y. 登録日 2021-02-27 公開日 2022-08-10 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Branched Lys48-Lys63-linked triubiquitin To be published
7NPI	Crystal structure of Mindy2 (C266A) in complex with Lys48-linked penta-ubiquitin (K48-Ub5) 分子名称: CHLORIDE ION, Polyubiquitin-C, SODIUM ION, ... 著者 Lange, S.M, Armstrong, L.A, Kulathu, Y. 登録日 2021-02-26 公開日 2021-09-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2. Mol.Cell, 81, 2021
7E62	Mouse TAB2 NZF in complex with Lys6-linked diubiquitin 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, TGF-beta-activated kinase 1 and MAP3K7-binding protein 2, Ubiquitin, ... 著者 Sato, Y, Li, Y, Okatsu, K, Fukai, S. 登録日 2021-02-21 公開日 2021-08-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structural basis for specific recognition of K6-linked polyubiquitin chains by the TAB2 NZF domain. Biophys.J., 120, 2021
7LTO	Nse5-6 complex 分子名称: Non-structural maintenance of chromosome element 5, Ubiquitin-like protein SMT3,DNA repair protein KRE29 chimera 著者 Yu, Y, Li, S.B, Zheng, S, Tangy, S, Koyi, C, Wan, B.B, Kung, H.H, Andrej, S, Alex, K, Patel, D.J, Zhao, X.L. 登録日 2021-02-19 公開日 2021-05-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Integrative analysis reveals unique structural and functional features of the Smc5/6 complex. Proc.Natl.Acad.Sci.USA, 118, 2021

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