7P0V

Crystal structure of human SF3A1 ubiquitin-like domain in complex with U1 snRNA stem-loop 4

Summary for 7P0V

• Entry DOI: 10.2210/pdb7p0v/pdb
• Related: 7P08
• Descriptor: Isoform 2 of Splicing factor 3A subunit 1, RNA (5'-R(P*GP*GP*GP*GP*AP*CP*UP*GP*CP*GP*UP*UP*CP*GP*CP*GP*CP*UP*UP*UP*CP*CP*CP*C)-3'), PENTAETHYLENE GLYCOL, ... (5 entities in total)
• Functional Keywords: splicing, rgg/rg motif, intrinsically disordered region, rna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 18129.72

Authors

Sabath, K.,de Vries, T.,Jonas, S. (deposition date: 2021-06-30, release date: 2022-04-20, Last modification date: 2024-01-31)

• Primary citation: de Vries, T.,Martelly, W.,Campagne, S.,Sabath, K.,Sarnowski, C.P.,Wong, J.,Leitner, A.,Jonas, S.,Sharma, S.,Allain, F.H.; Sequence-specific RNA recognition by an RGG motif connects U1 and U2 snRNP for spliceosome assembly.; Proc.Natl.Acad.Sci.USA, 119:-, 2022; PubMed: 35101980; DOI: 10.1073/pnas.2114092119

Experimental method

X-RAY DIFFRACTION (1.56 Å)