PDB: 5793 件ウェブページステータス検索Chemie searchBIRD

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5K92	Crystal Structure of an apo Tris-thiolate Binding Site in a de novo Three Stranded Coiled Coil Peptide 分子名称: Apo-(CSL16C)3, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Ruckthong, L, Zastrow, M.L, Stuckey, J.A, Pecoraro, V.L. 登録日 2016-05-31 公開日 2016-08-31 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 A Crystallographic Examination of Predisposition versus Preorganization in de Novo Designed Metalloproteins. J.Am.Chem.Soc., 138, 2016
7RDH	Crystal structure of the de novo designed binding protein H3mb in complex with the 1968 influenza A virus hemagglutinin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, De novo designed protein H3mb, ... 著者 Kadam, R.U, Wilson, I.A. 登録日 2021-07-09 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Design of protein-binding proteins from the target structure alone. Nature, 605, 2022
7BID	Crystal structure of v31WRAP-T, a 7-bladed designer protein 分子名称: v31WRAP-T 著者 Laier, I, Mylemans, B, Lee, X.Y, Voet, A.R.D. 登録日 2021-01-12 公開日 2021-09-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure and stability of the designer protein WRAP-T and its permutants. Sci Rep, 11, 2021
7BIF	Crystal structure of v22WRAP-T, a 7-bladed designer protein 分子名称: v22WRAP-T 著者 Lee, X.Y, Mylemans, B, Laier, I, Voet, A.R.D. 登録日 2021-01-12 公開日 2021-09-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure and stability of the designer protein WRAP-T and its permutants. Sci Rep, 11, 2021
7BIG	Crystal structure of v13WRAP-T, a 7-bladed designer protein 分子名称: CHLORIDE ION, v13WRAP-T 著者 Lee, X.Y, Mylemans, B, Laier, I, Voet, A.R.D. 登録日 2021-01-12 公開日 2021-09-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure and stability of the designer protein WRAP-T and its permutants. Sci Rep, 11, 2021
7TYD	Crystal structure of FGFR4 domain 3 in complex with a de novo-designed mini-binder in P21 space group 分子名称: Binder, Fibroblast growth factor receptor 4 著者 Park, J.S, Lee, S. 登録日 2022-02-12 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein. Cell Rep, 41, 2022
1S9Z	SYNTHETIC 17 AMINO ACID LONG PEPTIDE THAT FORMS A NATIVE-LIKE COILED-COIL AT AMBIENT TEMPERATURE AND AGGREGATES INTO AMYLOID-LIKE FIBRILS AT HIGHER TEMPERATURES. 分子名称: SODIUM ION, SYNTHETIC COILED-COIL PEPTIDE, ZINC ION 著者 Kammerer, R.A, Kostrewa, D, Zurdo, J, Detken, A, Garcia-Echeverria, C, Green, J.D, Muller, S.A, Meier, B.H, Winkler, F.K, Dobson, C.M, Steinmetz, M.O. 登録日 2004-02-06 公開日 2004-04-06 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Exploring amyloid formation by a de novo design Proc.Natl.Acad.Sci.USA, 101, 2004
8UGC	FD15: Flat repeat helix-turn-helix-turn protein 分子名称: FD15 著者 Davila-Hernandez, F, Bera, A.K, Kang, A, Baker, D. 登録日 2023-10-05 公開日 2023-12-27 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Directing polymorph specific calcium carbonate formation with de novo protein templates. Nat Commun, 14, 2023
6CO2	Structure of an engineered protein (NUDT16TI) in complex with 53BP1 Tudor domains 分子名称: NUDT16-Tudor-interacting (NUDT16TI), TP53-binding protein 1 著者 Botuyan, M.V, Thompson, J.R, Cui, G, Mer, G. 登録日 2018-03-10 公開日 2018-06-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein. Nat. Struct. Mol. Biol., 25, 2018
6CO1	Structure of human TIRR in complex with 53BP1 Tudor domains 分子名称: TP53-binding protein 1, Tudor-interacting repair regulator protein 著者 Cui, G, Botuyan, M.V, Mer, G. 登録日 2018-03-10 公開日 2018-06-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.179 Å) 主引用文献 Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein. Nat. Struct. Mol. Biol., 25, 2018
6D0L	Structure of human TIRR 分子名称: Tudor-interacting repair regulator protein 著者 Cui, G, Botuyan, M.V, Mer, G. 登録日 2018-04-10 公開日 2018-06-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein. Nat. Struct. Mol. Biol., 25, 2018
1OVV	CRYSTAL STRUCTURE OF FOUR-HELIX BUNDLE MODEL di-Co(II)-DF1-L13A (form II) 分子名称: COBALT (II) ION, FOUR-HELIX BUNDLE MODEL di-Co(II)-DF1-L13A (form II) 著者 Di Costanzo, L, Geremia, S. 登録日 2003-03-27 公開日 2004-04-06 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Response of a designed metalloprotein to changes in metal ion coordination, exogenous ligands, and active site volume determined by X-ray crystallography. J.Am.Chem.Soc., 127, 2005
5ZEO	X-ray structure of sperm whale V21C/V66C/F46S myoglobin mutant with an intramolecular disulfide bond 分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE 著者 Yuan, H. 登録日 2018-02-27 公開日 2018-05-09 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Regulation of both the structure and function by a de novo designed disulfide bond: a case study of heme proteins in myoglobin Chem. Commun. (Camb.), 54, 2018
1OVR	CRYSTAL STRUCTURE OF FOUR-HELIX BUNDLE MODEL di-Mn(II)-DF1-L13 分子名称: MANGANESE (II) ION, four-helix bundle model di-Mn(II)-DF1-L13 著者 Di Costanzo, L, Geremia, S. 登録日 2003-03-27 公開日 2004-05-18 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Response of a designed metalloprotein to changes in metal ion coordination, exogenous ligands, and active site volume determined by X-ray crystallography. J.Am.Chem.Soc., 127, 2005
1OVU	CRYSTAL STRUCTURE OF FOUR-HELIX BUNDLE MODEL di-Co(II)-DF1-L13A (form I) 分子名称: COBALT (II) ION, four-helix bundle model di-Co(II)-DF1-L13A (form I) 著者 Di Costanzo, L, Geremia, S. 登録日 2003-03-27 公開日 2004-04-06 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Response of a designed metalloprotein to changes in metal ion coordination, exogenous ligands, and active site volume determined by X-ray crystallography. J.Am.Chem.Soc., 127, 2005
6DHZ	Crystallographic octamer of a metal-free RIDC1 variant bearing two disulfide bonded cysteines 分子名称: CALCIUM ION, HEME C, Soluble cytochrome b562 著者 Tezcan, F.A, Churchfield, L.A. 登録日 2018-05-21 公開日 2018-07-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Determining the Structural and Energetic Basis of Allostery in a De Novo Designed Metalloprotein Assembly. J. Am. Chem. Soc., 140, 2018
6DHY	Crystallogrpahic tetramer of Zn-bound RIDC1 variant bearing two disulfide bonded cysteines 分子名称: CALCIUM ION, HEME C, Soluble cytochrome b562, ... 著者 Tezcan, F.A, Churchfield, L.A. 登録日 2018-05-21 公開日 2018-07-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Determining the Structural and Energetic Basis of Allostery in a De Novo Designed Metalloprotein Assembly. J. Am. Chem. Soc., 140, 2018
6Q5N	Crystal structure of a CC-Hex mutant that forms a parallel six-helix coiled coil CC-Hex*-L24Nle 分子名称: 1,4-DIETHYLENE DIOXIDE, CC-Hex*-L24Nle, GLYCEROL 著者 Wood, C.W, Beesley, J.L, Rhys, G.G, Brady, R.L, Woolfson, D.N. 登録日 2018-12-09 公開日 2019-05-22 最終更新日 2019-06-19 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Navigating the Structural Landscape of De Novo alpha-Helical Bundles. J.Am.Chem.Soc., 141, 2019
6Q5R	Crystal structure of a CC-Hex mutant that forms an antiparallel four-helix coiled coil CC-Hex*-LL-KgEb 分子名称: CC-Hex*-LL-KgEb, GLYCEROL 著者 Beesley, J.L, Rhys, G.G, Wood, C.W, Brady, R.L, Woolfson, D.N. 登録日 2018-12-09 公開日 2019-05-22 最終更新日 2019-06-19 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Navigating the Structural Landscape of De Novo alpha-Helical Bundles. J.Am.Chem.Soc., 141, 2019
6Q5H	Crystal structure of a CC-Hex mutant that forms an antiparallel four-helix coiled coil CC-Hex*-L24D 分子名称: AMMONIUM ION, CC-Hex*-L24D, SULFATE ION 著者 Wood, C.W, Beesley, J.L, Rhys, G.G, Brady, R.L, Woolfson, D.N. 登録日 2018-12-09 公開日 2019-05-22 最終更新日 2019-06-19 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Navigating the Structural Landscape of De Novo alpha-Helical Bundles. J.Am.Chem.Soc., 141, 2019
6Q5K	Crystal structure of a CC-Hex mutant that forms an antiparallel four-helix coiled coil CC-Hex*-L24K 分子名称: AMMONIUM ION, CC-Hex*-L24K, GLYCEROL, ... 著者 Wood, C.W, Beesley, J.L, Rhys, G.G, Brady, R.L, Woolfson, D.N. 登録日 2018-12-09 公開日 2019-05-22 最終更新日 2019-06-19 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Navigating the Structural Landscape of De Novo alpha-Helical Bundles. J.Am.Chem.Soc., 141, 2019
6Q5Q	Crystal structure of a CC-Hex mutant that forms an antiparallel four-helix coiled coil CC-Hex-KgEb 分子名称: CC-Hex-KgEb, L(+)-TARTARIC ACID 著者 Zaccai, N.R, Rhys, G.G, Wood, C.W, Beesley, J.L, Brady, R.L, Woolfson, D.N. 登録日 2018-12-09 公開日 2019-05-22 最終更新日 2019-06-19 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 Navigating the Structural Landscape of De Novo alpha-Helical Bundles. J.Am.Chem.Soc., 141, 2019
6Q5J	Crystal structure of a CC-Hex mutant that forms a parallel six-helix coiled coil CC-Hex*-L24E 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CC-Hex*-L24E 著者 Rhys, G.G, Wood, C.W, Beesley, J.L, Brady, R.L, Woolfson, D.N. 登録日 2018-12-09 公開日 2019-05-22 最終更新日 2019-06-19 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Navigating the Structural Landscape of De Novo alpha-Helical Bundles. J.Am.Chem.Soc., 141, 2019
6Q5M	Crystal structure of a CC-Hex mutant that forms an antiparallel four-helix coiled coil CC-Hex*-L24Dab 分子名称: CC-Hex*-L24Dab, SODIUM ION 著者 Wood, C.W, Beesley, J.L, Rhys, G.G, Brady, R.L, Woolfson, D.N. 登録日 2018-12-09 公開日 2019-05-22 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Navigating the Structural Landscape of De Novo alpha-Helical Bundles. J.Am.Chem.Soc., 141, 2019
4C11	Dengue virus RNA dependent RNA polymerase with residues from the NS5 linker region 分子名称: DENGUE VIRUS TYPE 3 RNA DEPENDENT RNA POLYMERASE, ZINC ION 著者 Lim, S.P, Lescar, J. 登録日 2013-08-09 公開日 2013-08-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A Crystal Structure of the Dengue Virus Ns5 Polymerase Delineates Inter-Domain Amino Acids Residues that Enhance its Thermostability and De Novo Initiation Activities. J.Biol.Chem., 288, 2013

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