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1UY6
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Human Hsp90-alpha with 9-Butyl-8-(3,4,5-trimethoxy-benzyl)-9H-purin-6-ylamine
分子名称: 9-BUTYL-8-(3,4,5-TRIMETHOXYBENZYL)-9H-PURIN-6-AMINE, HEAT SHOCK PROTEIN HSP 90-ALPHA
著者Wright, L, Barril, X, Dymock, B, Sheridan, L, Surgenor, A, Beswick, M, Drysdale, M, Collier, A, Massey, A, Davies, N, Fink, A, Fromont, C, Aherne, W, Boxall, K, Sharp, S, Workman, P, Hubbard, R.E.
登録日2004-03-02
公開日2004-07-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms
Chem.Biol., 11, 2004
1L98
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PERTURBATION OF TRP 138 IN T4 LYSOZYME BY MUTATIONS AT GLN 105 USED TO CORRELATE CHANGES IN STRUCTURE, STABILITY, SOLVATION, AND SPECTROSCOPIC PROPERTIES
分子名称: BETA-MERCAPTOETHANOL, T4 LYSOZYME
著者Pjura, P, Mcintosh, L.P, Wozniak, J.A, Matthews, B.W.
登録日1992-07-13
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Perturbation of Trp 138 in T4 lysozyme by mutations at Gln 105 used to correlate changes in structure, stability, solvation, and spectroscopic properties.
Proteins, 15, 1993
1V9W
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Solution structure of mouse putative 42-9-9 protein
分子名称: putative 42-9-9 protein
著者Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-02-03
公開日2004-08-03
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of mouse putative 42-9-9 protein
To be Published
1L00
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PERTURBATION OF TRP 138 IN T4 LYSOZYME BY MUTATIONS AT GLN 105 USED TO CORRELATE CHANGES IN STRUCTURE, STABILITY, SOLVATION, AND SPECTROSCOPIC PROPERTIES
分子名称: BETA-MERCAPTOETHANOL, T4 LYSOZYME
著者Pjura, P, Mcintosh, L.P, Wozniak, J.A, Matthews, B.W.
登録日1992-07-13
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Perturbation of Trp 138 in T4 lysozyme by mutations at Gln 105 used to correlate changes in structure, stability, solvation, and spectroscopic properties.
Proteins, 15, 1993
1L99
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BU of 1l99 by Molmil
PERTURBATION OF TRP 138 IN T4 LYSOZYME BY MUTATIONS AT GLN 105 USED TO CORRELATE CHANGES IN STRUCTURE, STABILITY, SOLVATION, AND SPECTROSCOPIC PROPERTIES
分子名称: BETA-MERCAPTOETHANOL, T4 LYSOZYME
著者Pjura, P, Mcintosh, L.P, Wozniak, J.A, Matthews, B.W.
登録日1992-07-13
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Perturbation of Trp 138 in T4 lysozyme by mutations at Gln 105 used to correlate changes in structure, stability, solvation, and spectroscopic properties.
Proteins, 15, 1993
1V32
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Solution structure of the SWIB/MDM2 domain of the hypothetical protein At5g08430 from Arabidopsis thaliana
分子名称: hypothetical protein RAFL09-47-K03
著者Yoneyama, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-10-24
公開日2004-04-24
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the SWIB/MDM2 domain of the hypothetical protein At5g08430 from Arabidopsis thaliana
To be Published
1V6E
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Solution Structure of a N-terminal Ubiquitin-like Domain in Mouse Tubulin-specific Chaperone B
分子名称: cytoskeleton-associated protein 1
著者Zhao, C, Kigawa, T, Saito, K, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-11-29
公開日2004-12-14
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution Structure of a N-terminal Ubiquitin-like Domain in Mouse Tubulin-specific Chaperone B
To be Published
222L
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GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W.
登録日1997-06-25
公開日1998-03-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions.
J.Mol.Biol., 277, 1998
230L
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T4 LYSOZYME MUTANT M6L
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Lipscomb, L.A, Gassner, N.C, Snow, S, Eldridge, A.M, Drew, D.L, Baase, W.A, Matthews, B.W.
登録日1997-10-02
公開日1998-01-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme.
Protein Sci., 7, 1998
1ZZ1
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Crystal structure of a HDAC-like protein with SAHA bound
分子名称: Histone deacetylase-like amidohydrolase, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, POTASSIUM ION, ...
著者Nielsen, T.K, Hildmann, C, Dickmanns, A, Schwienhorst, A, Ficner, R.
登録日2005-06-13
公開日2005-11-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Crystal structure of a bacterial class 2 histone deacetylase homologue
J.Mol.Biol., 354, 2005
268D
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STRUCTURAL STUDIES ON NUCLEIC ACIDS
分子名称: BERENIL, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(5CM)P*GP*CP*G)-3'), MAGNESIUM ION
著者Partridge, B.L, Salisbury, S.A.
登録日1996-07-12
公開日1996-08-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献
To be Published, 1996
1UUQ
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BU of 1uuq by Molmil
Exo-mannosidase from Cellvibrio mixtus
分子名称: GLYCEROL, MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE, SULFATE ION
著者Dias, M.V.F, Vincent, F, Pell, G, Prates, J.A.M, Centeno, M.S.J, Ferreira, L.M.A, Gilbert, H.J, Davies, G.J, Fontes, C.M.G.A.
登録日2004-01-09
公開日2004-04-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Insights Into the Molecular Determinants of Substrate Specificity in Glycoside Hydrolase Family 5 Revealed by the Crystal Structure and Kinetics of Cellvibrio Mixtus Mannosidase 5A
J.Biol.Chem., 279, 2004
227L
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BU of 227l by Molmil
GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS
分子名称: BENZENE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
著者Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W.
登録日1997-06-25
公開日1998-03-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions.
J.Mol.Biol., 277, 1998
2A2X
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BU of 2a2x by Molmil
Orally Active Thrombin Inhibitors in Complex with Thrombin Inh12
分子名称: N-(CARBOXYMETHYL)-3-CYCLOHEXYL-D-ALANYL-N-({6-[AMINO(IMINO)METHYL]PYRIDIN-3-YL}METHYL)-N~2~-METHYL-L-ALANINAMIDE, Thrombin heavy chain, Thrombin light chain, ...
著者Lange, U.E.W, Baucke, D, Hornberger, W, Mack, H, Seitz, W, Hoeffken, H.W.
登録日2005-06-23
公開日2006-11-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Orally active thrombin inhibitors. Part 2: optimization of the P2-moiety
BIOORG.MED.CHEM.LETT., 16, 2006
1M33
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Crystal Structure of BioH at 1.7 A
分子名称: 1,2-ETHANEDIOL, 3-HYDROXY-PROPANOIC ACID, BioH protein
著者Sanishvili, R, Savchenko, A, Skarina, T, Edwards, A, Joachimiak, A, Yakunin, A, Midwest Center for Structural Genomics (MCSG)
登録日2002-06-26
公開日2003-01-21
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli.
J.Biol.Chem., 278, 2003
1UWW
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X-ray crystal structure of a non-crystalline cellulose specific carbohydrate-binding module: CBM28.
分子名称: CALCIUM ION, ENDOGLUCANASE
著者Jamal, S, Nurizzo, D, Boraston, A, Davies, G.J.
登録日2004-02-12
公開日2004-05-13
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献X-Ray Crystal Structure of a Non-Crystalline Cellulose-Specific Carbohydrate-Binding Module: Cbm28
J.Mol.Biol., 339, 2004
1UP0
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Structure of the endoglucanase Cel6 from Mycobacterium tuberculosis in complex with cellobiose at 1.75 angstrom
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETATE ION, PUTATIVE CELLULASE CEL6, ...
著者Varrot, A, Leydier, S, Pell, G, Gilbert, H.J, Davies, G.J.
登録日2003-09-26
公開日2004-11-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mycobacterium Tuberculosis Strains Possess Functional Cellulases.
J.Biol.Chem., 280, 2005
2A97
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Crystal structure of catalytic domain of Clostridium botulinum neurotoxin serotype F
分子名称: Botulinum neurotoxin type F, CADMIUM ION, ZINC ION
著者Agarwal, R, Binz, T, Swaminathan, S.
登録日2005-07-11
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural analysis of botulinum neurotoxin serotype f light chain: implications on substrate binding and inhibitor design
Biochemistry, 44, 2005
1W2F
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Human Inositol (1,4,5)-trisphosphate 3-kinase substituted with selenomethionine
分子名称: INOSITOL-TRISPHOSPHATE 3-KINASE A, SULFATE ION
著者Gonzalez, B, Schell, M.J, Irvine, R.F, Williams, R.L.
登録日2004-07-01
公開日2004-09-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a Human Inositol 1,4,5-Trisphosphate 3-Kinase; Substrate Binding Reveals Why It is not a Phosphoinositide 3-Kinase
Mol.Cell, 15, 2004
2A9X
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TAR RNA recognition by a cyclic peptidomimetic of Tat protein
分子名称: BIV TAR RNA, BIV-2 cyclic peptide
著者Leeper, T.C, Athanassiou, Z, Dias, R.L, Robinson, J.A, Varani, G.
登録日2005-07-12
公開日2005-11-01
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献TAR RNA recognition by a cyclic peptidomimetic of Tat protein.
Biochemistry, 44, 2005
1MAF
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The Active Site Structure of Methylamine Dehydrogenase: Hydrazines Identify C6 as the Reactive Site of the Tryptophan Derived Quinone Cofactor
分子名称: METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT), METHYLAMINE DEHYDROGENASE (LIGHT SUBUNIT), NITROGEN MOLECULE
著者Huizinga, E.G, Vellieux, F.M.D, Hol, W.G.J.
登録日1992-05-20
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor.
Biochemistry, 31, 1992
1WFV
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Solution structure of the fifth PDZ domain of human membrane associated guanylate kinase inverted-2 (KIAA0705 protein)
分子名称: membrane associated guanylate kinase inverted-2
著者Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-27
公開日2004-11-27
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the fifth PDZ domain of human membrane associated guanylate kinase inverted-2 (KIAA0705 protein)
To be Published
2A4D
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Structure of the human ubiquitin-conjugating enzyme E2 variant 1 (UEV-1)
分子名称: Ubiquitin-conjugating enzyme E2 variant 1
著者Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2005-06-28
公開日2005-07-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
1WFS
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Solution Structure of Glia Maturation Factor-gamma from Mus Musculus
分子名称: Glia maturation factor gamma
著者Goroncy, A.K, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-26
公開日2004-11-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR solution structures of actin depolymerizing factor homology domains.
Protein Sci., 18, 2009
1WCK
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Crystal structure of the C-terminal domain of BclA, the major antigen of the exosporium of the Bacillus anthracis spore.
分子名称: BCLA PROTEIN, CACODYLATE ION
著者Rety, S, Salamitou, S, Augusto, L.A, Chaby, R, Lehegarat, F, Lewit-Bentley, A.
登録日2004-11-17
公開日2005-10-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献The Crystal Structure of the Bacillus Anthracis Spore Surface Protein Bcla Shows Remarkable Similarity to Mammalian Proteins.
J.Biol.Chem., 280, 2005

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