1MJV
| DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C51A and C60A) | 分子名称: | Vascular Endothelial Growth Factor A | 著者 | Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H. | 登録日 | 2002-08-28 | 公開日 | 2002-12-11 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor J.Biol.Chem., 277, 2002
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1YXT
| Crystal Structure of Kinase Pim1 in complex with AMPPNP | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Proto-oncogene serine/threonine-protein kinase Pim-1 | 著者 | Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R. | 登録日 | 2005-02-22 | 公開日 | 2005-04-26 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma. J.Mol.Biol., 348, 2005
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1Z0J
| Structure of GTP-Bound Rab22Q64L GTPase in complex with the minimal Rab binding domain of Rabenosyn-5 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FYVE-finger-containing Rab5 effector protein rabenosyn-5, GLYCEROL, ... | 著者 | Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. | 登録日 | 2005-03-01 | 公開日 | 2005-07-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | Structural basis of family-wide Rab GTPase recognition by rabenosyn-5. Nature, 436, 2005
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1YWQ
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1KO2
| VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa with an oxidized Cys (cysteinesulfonic) | 分子名称: | ACETATE ION, VIM-2 metallo-beta-lactamase, ZINC ION | 著者 | Garcia-Saez, I, Docquier, J.-D, Rossolini, G.M, Dideberg, O. | 登録日 | 2001-12-20 | 公開日 | 2003-09-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The three-dimensional structure of VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form J.Mol.Biol., 375, 2008
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1KT3
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1KVI
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1ZCJ
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1ZBN
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1ZJ7
| Crystal structure of a complex of mutant HIV-1 protease (A71V, V82T, I84V) with a hydroxyethylamine peptidomimetic inhibitor BOC-PHE-PSI[S-CH(OH)CH2NH]-PHE-GLU-PHE-NH2 | 分子名称: | N-{(2S,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4-phenylbutyl}-L-phenylalanyl-L-alpha-glutamyl-L-phenylalaninamide, PROTEASE RETROPEPSIN | 著者 | Skalova, T, Dohnalek, J, Duskova, J, Petrokova, H, Hasek, J. | 登録日 | 2005-04-28 | 公開日 | 2006-05-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | HIV-1 protease mutations and inhibitor modifications monitored on a series of complexes. Structural basis for the effect of the A71V mutation on the active site J.Med.Chem., 49, 2006
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1ZLF
| Crystal structure of a complex of mutant HIV-1 protease (A71V, V82T, I84V) with a hydroxyethylamine peptidomimetic inhibitor | 分子名称: | N-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4-phenylbutyl}-L-phenylalanyl-L-glutaminyl-L-phenylalaninamide, PROTEASE RETROPEPSIN | 著者 | Skalova, T, Dohnalek, J, Duskova, J, Petrokova, H, Hasek, J. | 登録日 | 2005-05-06 | 公開日 | 2006-04-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | HIV-1 protease mutations and inhibitor modifications monitored on a series of complexes. Structural basis for the effect of the A71V mutation on the active site J.Med.Chem., 49, 2006
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1ZPA
| HIV Protease with Scripps AB-3 Inhibitor | 分子名称: | Pol polyprotein, TERT-BUTYL 4-[({[1-((1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL)-1H-1,2,3-TRIAZOL-4-YL]METHYL}AMINO)CARBONYL]BENZYLCARBAMATE | 著者 | Brik, A, Alexandratos, J, Lin, Y.C, Elder, J.H, Olson, A.J, Wlodawer, A, Goodsell, D.S, Wong, C.H. | 登録日 | 2005-05-16 | 公開日 | 2005-05-31 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | 1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors Chembiochem, 6, 2005
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1KX6
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1M9P
| Crystalline Human Carbonmonoxy Hemoglobin C Exhibits The R2 Quaternary State at Neutral pH In The Presence of Polyethylene Glycol: The 2.1 Angstrom Resolution Crystal Structure | 分子名称: | CARBON MONOXIDE, Hemoglobin alpha chain, Hemoglobin beta chain, ... | 著者 | Patskovska, L.N, Patskovsky, Y.V, Almo, S.C, Hirsch, R.E. | 登録日 | 2002-07-29 | 公開日 | 2003-08-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | COHbC and COHbS crystallize in the R2 quaternary state at neutral pH in the presence of PEG 4000. Acta Crystallogr.,Sect.D, 61, 2005
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2A9X
| TAR RNA recognition by a cyclic peptidomimetic of Tat protein | 分子名称: | BIV TAR RNA, BIV-2 cyclic peptide | 著者 | Leeper, T.C, Athanassiou, Z, Dias, R.L, Robinson, J.A, Varani, G. | 登録日 | 2005-07-12 | 公開日 | 2005-11-01 | 最終更新日 | 2022-03-09 | 実験手法 | SOLUTION NMR | 主引用文献 | TAR RNA recognition by a cyclic peptidomimetic of Tat protein. Biochemistry, 44, 2005
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266D
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28DN
| CRYSTAL STRUCTURE ANALYSIS OF AN A(DNA) OCTAMER D(GTACGTAC) | 分子名称: | DNA (5'-D(*GP*TP*AP*CP*GP*TP*AP*C)-3') | 著者 | Courseille, C, Dautant, A, Hospital, M, Langlois D'Estaintot, B, Precigoux, G, Molko, D, Teoule, R. | 登録日 | 1990-05-03 | 公開日 | 1991-07-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure Analysis of an A(DNA) Octamer d(GTACGTAC) Acta Crystallogr.,Sect.A, 46, 1990
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1MQJ
| Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with willardiine at 1.65 angstroms resolution | 分子名称: | 2-AMINO-3-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, ZINC ION, glutamate receptor 2 | 著者 | Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E. | 登録日 | 2002-09-16 | 公開日 | 2003-08-05 | 最終更新日 | 2017-08-02 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural basis for partial agonist action at ionotropic glutamate receptors Nat.Neurosci., 6, 2003
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2A2V
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1MHW
| Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides | 分子名称: | 4-biphenylacetyl-Cys-(D)Arg-Tyr-N-(2-phenylethyl) amide, Cathepsin L | 著者 | Chowdhury, S, Sivaraman, J, Wang, J, Devanathan, G, Lachance, P, Qi, H, Menard, R, Lefebvre, J, Konishi, Y, Cygler, M, Sulea, T, Purisima, E.O. | 登録日 | 2002-08-21 | 公開日 | 2002-12-11 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides J.Med.Chem., 45, 2002
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285D
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2AAP
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2A15
| X-ray Crystal Structure of RV0760 from Mycobacterium Tuberculosis at 1.68 Angstrom Resolution | 分子名称: | HYPOTHETICAL PROTEIN Rv0760c, NICOTINAMIDE | 著者 | Garen, C.R, Cherney, M.M, James, M.N.G, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2005-06-17 | 公開日 | 2005-10-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase Biochim.Biophys.Acta, 1784, 2008
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2A48
| Crystal structure of amFP486 E150Q | 分子名称: | BETA-MERCAPTOETHANOL, GFP-like fluorescent chromoprotein amFP486 | 著者 | Henderson, J.N, Remington, S.J. | 登録日 | 2005-06-28 | 公開日 | 2005-08-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures and mutational analysis of amFP486, a cyan fluorescent protein from Anemonia majano Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AAY
| EPSP synthase liganded with shikimate and glyphosate | 分子名称: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, ... | 著者 | Priestman, M.A, Healy, M.L, Funke, T, Becker, A. | 登録日 | 2005-07-14 | 公開日 | 2006-02-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Molecular basis for the glyphosate-insensitivity of the reaction of 5-enolpyruvylshikimate 3-phosphate synthase with shikimate. Febs Lett., 579, 2005
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