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1MJV
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DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C51A and C60A)
分子名称: Vascular Endothelial Growth Factor A
著者Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H.
登録日2002-08-28
公開日2002-12-11
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor
J.Biol.Chem., 277, 2002
1YXT
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Crystal Structure of Kinase Pim1 in complex with AMPPNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1Z0J
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Structure of GTP-Bound Rab22Q64L GTPase in complex with the minimal Rab binding domain of Rabenosyn-5
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FYVE-finger-containing Rab5 effector protein rabenosyn-5, GLYCEROL, ...
著者Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G.
登録日2005-03-01
公開日2005-07-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
1YWQ
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Crystal structure of a nitroreductase family protein from Bacillus cereus ATCC 14579
分子名称: FLAVIN MONONUCLEOTIDE, Nitroreductase family protein
著者Midwest Center for Structural Genomics (MCSG)
登録日2005-02-18
公開日2005-04-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a nitroreductase family protein from Bacillus cereus ATCC 14579
To be Published
1KO2
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VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa with an oxidized Cys (cysteinesulfonic)
分子名称: ACETATE ION, VIM-2 metallo-beta-lactamase, ZINC ION
著者Garcia-Saez, I, Docquier, J.-D, Rossolini, G.M, Dideberg, O.
登録日2001-12-20
公開日2003-09-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The three-dimensional structure of VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form
J.Mol.Biol., 375, 2008
1KT3
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Crystal structure of bovine holo-RBP at pH 2.0
分子名称: Plasma retinol-binding protein, RETINOL
著者Calderone, V, Berni, R, Zanotti, G.
登録日2002-01-15
公開日2003-06-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献High-resolution Structures of Retinol-binding Protein in Complex with Retinol: pH-induced Protein Structural Changes in the Crystal State
J.Mol.Biol., 329, 2003
1KVI
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Solution Structure of the Reduced Form of the First Heavy Metal Binding Motif of the Menkes Protein
分子名称: Copper-transporting ATPase 1
著者De Silva, T.M, Veglia, G, Opella, S.J.
登録日2002-01-26
公開日2003-11-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structures of the reduced and Cu(I) bound forms of the first metal binding sequence of ATP7A associated with Menkes disease.
Proteins, 61, 2005
1ZCJ
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Crystal structure of 3-hydroxyacyl-CoA dehydrogenase
分子名称: Peroxisomal bifunctional enzyme
著者Taskinen, J.P, Kiema, T.R, Hiltunen, J.K, Wierenga, R.K.
登録日2005-04-12
公開日2006-01-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Studies of MFE-1: the 1.9A Crystal Structure of the Dehydrogenase Part of Rat Peroxisomal MFE-1
J.Mol.Biol., 355, 2006
1ZBN
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Solution structure of BIV TAR hairpin complexed to JDV Tat arginine-rich motif
分子名称: BIV mRNA, JDV tat protein
著者Calabro, V, Daugherty, M.D, Frankel, A.D.
登録日2005-04-08
公開日2005-04-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A single intermolecular contact mediates intramolecular stabilization of both RNA and protein.
Proc.Natl.Acad.Sci.Usa, 102, 2005
1ZJ7
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Crystal structure of a complex of mutant HIV-1 protease (A71V, V82T, I84V) with a hydroxyethylamine peptidomimetic inhibitor BOC-PHE-PSI[S-CH(OH)CH2NH]-PHE-GLU-PHE-NH2
分子名称: N-{(2S,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4-phenylbutyl}-L-phenylalanyl-L-alpha-glutamyl-L-phenylalaninamide, PROTEASE RETROPEPSIN
著者Skalova, T, Dohnalek, J, Duskova, J, Petrokova, H, Hasek, J.
登録日2005-04-28
公開日2006-05-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献HIV-1 protease mutations and inhibitor modifications monitored on a series of complexes. Structural basis for the effect of the A71V mutation on the active site
J.Med.Chem., 49, 2006
1ZLF
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Crystal structure of a complex of mutant HIV-1 protease (A71V, V82T, I84V) with a hydroxyethylamine peptidomimetic inhibitor
分子名称: N-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4-phenylbutyl}-L-phenylalanyl-L-glutaminyl-L-phenylalaninamide, PROTEASE RETROPEPSIN
著者Skalova, T, Dohnalek, J, Duskova, J, Petrokova, H, Hasek, J.
登録日2005-05-06
公開日2006-04-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献HIV-1 protease mutations and inhibitor modifications monitored on a series of complexes. Structural basis for the effect of the A71V mutation on the active site
J.Med.Chem., 49, 2006
1ZPA
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HIV Protease with Scripps AB-3 Inhibitor
分子名称: Pol polyprotein, TERT-BUTYL 4-[({[1-((1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL)-1H-1,2,3-TRIAZOL-4-YL]METHYL}AMINO)CARBONYL]BENZYLCARBAMATE
著者Brik, A, Alexandratos, J, Lin, Y.C, Elder, J.H, Olson, A.J, Wlodawer, A, Goodsell, D.S, Wong, C.H.
登録日2005-05-16
公開日2005-05-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors
Chembiochem, 6, 2005
1KX6
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NMR solution structure of Glucagon in a lipid-water interphase
分子名称: Glucagon
著者Braun, W, Wider, G, Lee, K.H, Wuthrich, K.
登録日2002-01-31
公開日2002-02-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Conformation of glucagon in a lipid-water interphase by 1H nuclear magnetic resonance.
J.Mol.Biol., 169, 1983
1M9P
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Crystalline Human Carbonmonoxy Hemoglobin C Exhibits The R2 Quaternary State at Neutral pH In The Presence of Polyethylene Glycol: The 2.1 Angstrom Resolution Crystal Structure
分子名称: CARBON MONOXIDE, Hemoglobin alpha chain, Hemoglobin beta chain, ...
著者Patskovska, L.N, Patskovsky, Y.V, Almo, S.C, Hirsch, R.E.
登録日2002-07-29
公開日2003-08-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献COHbC and COHbS crystallize in the R2 quaternary state at neutral pH in the presence of PEG 4000.
Acta Crystallogr.,Sect.D, 61, 2005
2A9X
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TAR RNA recognition by a cyclic peptidomimetic of Tat protein
分子名称: BIV TAR RNA, BIV-2 cyclic peptide
著者Leeper, T.C, Athanassiou, Z, Dias, R.L, Robinson, J.A, Varani, G.
登録日2005-07-12
公開日2005-11-01
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献TAR RNA recognition by a cyclic peptidomimetic of Tat protein.
Biochemistry, 44, 2005
266D
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STRUCTURAL STUDIES ON NUCLEIC ACIDS
分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(5CM)P*GP*CP*G)-3'), MAGNESIUM ION
著者Partridge, B.L, Salisbury, S.A.
登録日1996-07-12
公開日1996-08-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献
To be Published, 1996
28DN
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CRYSTAL STRUCTURE ANALYSIS OF AN A(DNA) OCTAMER D(GTACGTAC)
分子名称: DNA (5'-D(*GP*TP*AP*CP*GP*TP*AP*C)-3')
著者Courseille, C, Dautant, A, Hospital, M, Langlois D'Estaintot, B, Precigoux, G, Molko, D, Teoule, R.
登録日1990-05-03
公開日1991-07-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure Analysis of an A(DNA) Octamer d(GTACGTAC)
Acta Crystallogr.,Sect.A, 46, 1990
1MQJ
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Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with willardiine at 1.65 angstroms resolution
分子名称: 2-AMINO-3-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, ZINC ION, glutamate receptor 2
著者Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E.
登録日2002-09-16
公開日2003-08-05
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
2A2V
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The solution structure of Jingzhaotoxin-XI
分子名称: Jingzhaotoxin-XI
著者Liao, Z, Liang, S.P.
登録日2005-06-23
公開日2005-07-05
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献The solution structure of Jingzhaotoxin-XI
To be published
1MHW
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Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides
分子名称: 4-biphenylacetyl-Cys-(D)Arg-Tyr-N-(2-phenylethyl) amide, Cathepsin L
著者Chowdhury, S, Sivaraman, J, Wang, J, Devanathan, G, Lachance, P, Qi, H, Menard, R, Lefebvre, J, Konishi, Y, Cygler, M, Sulea, T, Purisima, E.O.
登録日2002-08-21
公開日2002-12-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides
J.Med.Chem., 45, 2002
285D
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X-RAY AND SOLUTION STUDIES OF DNA OLIGOMERS AND IMPLICATIONS FOR THE STRUCTURAL BASIS OF A-TRACT-DEPENDENT CURVATURE
分子名称: DNA (5'-D(*CP*GP*CP*AP*IP*AP*TP*(5CM)P*TP*GP*CP*G)-3')
著者Shatzky-Schwartz, M, Shakked, Z, Luisi, B.F.
登録日1996-09-11
公開日1997-05-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray and solution studies of DNA oligomers and implications for the structural basis of A-tract-dependent curvature.
J.Mol.Biol., 267, 1997
2AAP
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Solution structure of jingzhaotoxin-vii
分子名称: Jingzhaotoxin-Vii
著者Liao, Z, Liang, S.P.
登録日2005-07-14
公開日2005-08-02
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure of jingzhaotoxin-vii
TO BE PUBLISHED
2A15
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X-ray Crystal Structure of RV0760 from Mycobacterium Tuberculosis at 1.68 Angstrom Resolution
分子名称: HYPOTHETICAL PROTEIN Rv0760c, NICOTINAMIDE
著者Garen, C.R, Cherney, M.M, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2005-06-17
公開日2005-10-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase
Biochim.Biophys.Acta, 1784, 2008
2A48
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Crystal structure of amFP486 E150Q
分子名称: BETA-MERCAPTOETHANOL, GFP-like fluorescent chromoprotein amFP486
著者Henderson, J.N, Remington, S.J.
登録日2005-06-28
公開日2005-08-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures and mutational analysis of amFP486, a cyan fluorescent protein from Anemonia majano
Proc.Natl.Acad.Sci.Usa, 102, 2005
2AAY
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EPSP synthase liganded with shikimate and glyphosate
分子名称: (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, ...
著者Priestman, M.A, Healy, M.L, Funke, T, Becker, A.
登録日2005-07-14
公開日2006-02-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Molecular basis for the glyphosate-insensitivity of the reaction of 5-enolpyruvylshikimate 3-phosphate synthase with shikimate.
Febs Lett., 579, 2005

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