5Y0W
 
 | | The structure of RVFV Gn head domain | | 分子名称: | NSmGnGc | | 著者 | Wu, Y, Gao, F, Qi, J.X, Chai, Y, Gao, G.F. | | 登録日 | 2017-07-19 | | 公開日 | 2017-09-13 | | 最終更新日 | 2017-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7L87
 | | BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-2 from animal Rh.32034 (Wk26 time point) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ... | | 著者 | Antanasijevic, A, Sewall, L.M, Yang, Y.R, Perrett, H.R, Ward, A.B. | | 登録日 | 2020-12-31 | | 公開日 | 2021-08-04 | | 最終更新日 | 2021-11-24 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
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8YX9
 | | CD40 in complex with Dacetuzumab Fab | | 分子名称: | Dacetuzumab, Heavy chain, light chain, ... | | 著者 | Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. | | 登録日 | 2024-04-02 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab.
Biochem.Biophys.Res.Commun., 714, 2024
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8YX1
 | | CD40 in complex with Bleselumab Fab | | 分子名称: | Bleselumab, heavy chain, light chain, ... | | 著者 | Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. | | 登録日 | 2024-04-01 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab.
Biochem.Biophys.Res.Commun., 714, 2024
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7L86
 | | BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-1 from animal Rh.32034 (Wk26 time point) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ... | | 著者 | Antanasijevic, A, Sewall, L.M, Ward, A.B. | | 登録日 | 2020-12-31 | | 公開日 | 2021-08-04 | | 最終更新日 | 2021-11-24 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
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7L8E
 | | BG505 SOSIP.v5.2(7S) in complex with the polyclonal Fab pAbC-1 from animal Rh.33172 (Wk38 time point) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | | 著者 | Antanasijevic, A, Sewall, L.M, Ward, A.B. | | 登録日 | 2020-12-31 | | 公開日 | 2021-08-04 | | 最終更新日 | 2021-09-08 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
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7L8F
 | | BG505 SOSIP.v5.2(7S) in complex with the polyclonal Fab pAbC-2 from animal Rh.33172 (Wk38 time point) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | | 著者 | Antanasijevic, A, Sewall, L.M, Ward, A.B. | | 登録日 | 2020-12-31 | | 公開日 | 2021-08-04 | | 最終更新日 | 2021-09-08 | | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | | 主引用文献 | Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
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7WVP
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7WVQ
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7LUA
 | | Cryo-EM structure of DH898.1 Fab-dimer bound near the CD4 binding site of HIV-1 Env CH848 SOSIP trimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848 SOSIP gp120, ... | | 著者 | Manne, K, Edwards, R.J, Acharya, P. | | 登録日 | 2021-02-21 | | 公開日 | 2021-03-17 | | 最終更新日 | 2021-06-09 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
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7LSS
 | | Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2-7 variable heavy chain, ... | | 著者 | Rapp, M, Shapiro, L. | | 登録日 | 2021-02-18 | | 公開日 | 2021-03-17 | | 最終更新日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies.
Structure, 29, 2021
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7LU9
 | | Cryo-EM structure of DH851.3 bound to HIV-1 CH505 Env | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Manne, K, Edwards, R.J, Acharya, P. | | 登録日 | 2021-02-21 | | 公開日 | 2021-03-24 | | 最終更新日 | 2021-06-09 | | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | | 主引用文献 | Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
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7U5B
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6U02
 | | CryoEM-derived model of NA-63 Fab in complex with N9 Shanghai2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab-63 Heavy Chain, Fab-63 Light Chain, ... | | 著者 | Ward, A.B, Turner, H.L, Zhu, X. | | 登録日 | 2019-08-13 | | 公開日 | 2019-12-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
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7XLD
 | | Crystal structure of IsdH linker-NEAT3 bound to a nanobody (VHH) | | 分子名称: | Iron-regulated surface determinant protein H, MAGNESIUM ION, Nanobody VHH6, ... | | 著者 | Caaveiro, J.M.M, Valenciano-Bellido, S, Tsumoto, K. | | 登録日 | 2022-04-21 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Targeting hemoglobin receptors IsdH and IsdB of Staphylococcus aureus with a single VHH antibody inhibits bacterial growth.
J.Biol.Chem., 299, 2023
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4NJ9
 | | Crystal structure of Fab 8B10 in complex with MPTS | | 分子名称: | 8-methoxypyrene-1,3,6-trisulfonic acid, 8B10 heavy chain, 8B10 light chain, ... | | 著者 | Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A. | | 登録日 | 2013-11-08 | | 公開日 | 2014-11-12 | | 最終更新日 | 2017-06-14 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
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6WY1
 | | Crystal structure of an engineered thermostable dengue virus 2 envelope protein dimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dengue 2 soluble recombinant envelope | | 著者 | Kudlacek, S.T, Lakshmanane, P, Kuhlman, B. | | 登録日 | 2020-05-12 | | 公開日 | 2021-11-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | | 主引用文献 | Designed, highly expressing, thermostable dengue virus 2 envelope protein dimers elicit quaternary epitope antibodies.
Sci Adv, 7, 2021
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6A3V
 | | Complex structure of human 4-1BB and 4-1BBL | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9 | | 著者 | Li, Y, Zhang, C, Chai, Y, Qi, J, Tien, P, Gao, S, Gao, G.F. | | 登録日 | 2018-06-17 | | 公開日 | 2018-10-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.391 Å) | | 主引用文献 | Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab.
Cell Rep, 25, 2018
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7UMT
 | | Structure of the VP5*/VP8* assembly from the human rotavirus strain CDC-9 - Reversed conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Intermediate capsid protein VP6, ... | | 著者 | Jenni, S, Zongli, L, Wang, Y, Bessey, T, Salgado, E.N, Schmidt, A.G, Greenberg, H.B, Jiang, B, Harrison, S.C. | | 登録日 | 2022-04-07 | | 公開日 | 2022-07-27 | | 最終更新日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Rotavirus VP4 Epitope of a Broadly Neutralizing Human Antibody Defined by Its Structure Bound with an Attenuated-Strain Virion.
J.Virol., 96, 2022
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6A3W
 | | Complex structure of 4-1BB and utomilumab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor receptor superfamily member 9, utomilumab VH, ... | | 著者 | Li, Y, Tan, S, Zhang, C, Chai, Y, Qi, J, Tien, P, Gao, S, Gao, G.F. | | 登録日 | 2018-06-17 | | 公開日 | 2018-10-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab.
Cell Rep, 25, 2018
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4F5C
 | | Crystal structure of the spike receptor binding domain of a porcine respiratory coronavirus in complex with the pig aminopeptidase N ectodomain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | | 著者 | Santiago, C, Reguera, J, Gaurav, M, Ordono, D, Enjuanes, L, Casasnovas, J.M. | | 登録日 | 2012-05-13 | | 公開日 | 2012-08-22 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural bases of coronavirus attachment to host aminopeptidase N and its inhibition by neutralizing antibodies.
Plos Pathog., 8, 2012
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5ODB
 | | Crystal structure of the RA-associated mAb D10 (chimeric Fab fragment) | | 分子名称: | D10 Fab fragment - heavy chain, D10 Fab fragment - light chain, GLYCEROL, ... | | 著者 | Dobritzsch, D, Ge, C, Holmdahl, R, Amara, K, Malmstrom, V. | | 登録日 | 2017-07-05 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.
Arthritis Rheumatol, 71, 2019
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4NJA
 | | Crystal structure of Fab 6C8 in complex with MPTS | | 分子名称: | 6C8 heavy chain, 6C8 light chain, 8-methoxypyrene-1,3,6-trisulfonic acid, ... | | 著者 | Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A. | | 登録日 | 2013-11-08 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | | 主引用文献 | Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
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6BE3
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6BE4
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