PDB: 45817 件ウェブページステータス検索Chemie searchBIRD

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4K96	Structure of Binary Complex of cGAS with Bound dsDNA 分子名称: Cyclic GMP-AMP synthase, DNA-F, DNA-R, ... 著者 Gao, P, Wu, Y, Patel, D.J. 登録日 2013-04-19 公開日 2013-05-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.084 Å) 主引用文献 Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
4K98	Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG 分子名称: Cyclic GMP-AMP synthase, DNA-F, DNA-R, ... 著者 Gao, P, Wu, Y, Patel, D.J. 登録日 2013-04-19 公開日 2013-05-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
1YQK	Human 8-oxoguanine glycosylase crosslinked with guanine containing DNA 分子名称: 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*G)-3', 5'-D(P*CP*AP*GP*GP*TP*CP*TP*AP*C)-3', CALCIUM ION, ... 著者 Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. 登録日 2005-02-01 公開日 2005-04-05 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature, 434, 2005
1YQR	Catalytically inactive human 8-oxoguanine glycosylase crosslinked to oxoG containing DNA 分子名称: 5'-D(P*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3', CALCIUM ION, ... 著者 Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. 登録日 2005-02-02 公開日 2005-04-05 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature, 434, 2005
1YQL	Catalytically inactive hOGG1 crosslinked with 7-deaza-8-azaguanine containing DNA 分子名称: 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*CP*AP*(PPW)P*GP*TP*CP*TP*AP*C)-3', CALCIUM ION, ... 著者 Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. 登録日 2005-02-02 公開日 2005-04-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature, 434, 2005
3OHB	Yeast DNA polymerase eta extending from an 8-oxoG lesion 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*TP*CP*CP*TP*CP*CP*CP*CP*TP*(DOC))-3', 5'-D(*TP*AP*AP*TP*GP*(8OG)P*AP*GP*GP*GP*GP*AP*GP*GP*AP*C)-3', ... 著者 Silverstein, T.D, Jain, R, Aggarwal, A.K. 登録日 2010-08-17 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase eta. Structure, 18, 2010
4YHX	Crystal Structure of LAGLIDADG Meganuclease I-GpeMI Bound to Uncleaved DNA 分子名称: CALCIUM ION, DNA (27-MER), Ribosomal protein 3/homing endonuclease-like fusion protein 著者 Hallinan, J.P, Kaiser, B.K, Stoddard, B.L. 登録日 2015-02-27 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity. Structure, 24, 2016
1D61	THE STRUCTURE OF THE B-DNA DECAMER C-C-A-A-C-I-T-T-G-G: MONOCLINIC FORM 分子名称: CACODYLATE ION, CALCIUM ION, DNA (5'-D(*CP*CP*AP*AP*CP*IP*TP*TP*GP*G)-3') 著者 Lipanov, A, Kopka, M.L, Kaczor-Grzeskowiak, M, Quintana, J, Dickerson, R.E. 登録日 1992-02-26 公開日 1993-04-15 最終更新日 2023-07-26 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure of the B-DNA decamer C-C-A-A-C-I-T-T-G-G in two different space groups: conformational flexibility of B-DNA. Biochemistry, 32, 1993
4Z20	Crystal Structure of Meganuclease I-SmaMI Bound to Uncleaveable DNA with a TTGT Central Four 分子名称: CALCIUM ION, DNA (26-MER), GLYCEROL, ... 著者 Hallinan, J.P, Stoddard, B.L. 登録日 2015-03-27 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity. Structure, 24, 2016
4Z1Z	Crystal Structure of Meganuclease I-SmaMI Bound to Uncleaveable DNA with a TTCT Central Four 分子名称: CALCIUM ION, DNA (28-MER), GLYCEROL, ... 著者 Hallinan, J.P, Stoddard, B.L. 登録日 2015-03-27 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity. Structure, 24, 2016
4FYD	Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA and dGTP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*TP*GP*AP*GP*CP*GP*TP*G*TP*GP*TP*AP*CP*CP*CP*CP*TP*GP*CP*CP*CP*GP*CP*CP*G)-3'), DNA polymerase alpha catalytic subunit A, ... 著者 Perera, R.L, Pellegrini, L. 登録日 2012-07-04 公開日 2013-02-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha eLife, 2, 2013
6RIO	Imidazole Polyamide-DNA complex NMR structure (5'-CGATGTACATCG-3') 分子名称: 3-[3-[[4-[[4-[[4-[[4-[[(2~{R})-2-azaniumyl-4-[[1-methyl-4-[[1-methyl-4-[[1-methyl-4-[(1-methylimidazol-2-yl)carbonylamino]pyrrol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]butanoyl]amino]-1-methyl-imidazol-2-yl]carbonylamino]-1-methyl-pyrrol-2-yl]carbonylamino]-1-methyl-pyrrol-2-yl]carbonylamino]-1-methyl-pyrrol-2-yl]carbonylamino]propanoylamino]propyl-dimethyl-azanium, DNA (5'-(*(DC5)P*GP*AP*TP*GP*TP*AP*CP*AP*TP*CP*(DG3))-3') 著者 Padroni, G, Withers, J.M, Taladriz-Sender, A, Reichenbach, L.F, Parkinson, J.A, Burley, G.A. 登録日 2019-04-24 公開日 2019-06-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Sequence-Selective Minor Groove Recognition of a DNA Duplex Containing Synthetic Genetic Components. J.Am.Chem.Soc., 141, 2019
3UO7	Crystal structure of Human Thymine DNA Glycosylase Bound to Substrate 5-carboxylcytosine 分子名称: 5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*AP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(1CC)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', G/T mismatch-specific thymine DNA glycosylase 著者 Zhang, L, He, C. 登録日 2011-11-16 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.002 Å) 主引用文献 Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat.Chem.Biol., 8, 2012
3FOF	Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases 分子名称: 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, DNA (5'-D(P*AP*CP*CP*AP*AP*GP*GP*TP*CP*AP*TP*GP*AP*AP*T)-3'), DNA (5'-D(P*AP*GP*TP*CP*AP*TP*TP*CP*AP*TP*GP*AP*CP*CP*TP*TP*GP*GP*T)-3'), ... 著者 Laponogov, I, Sohi, M.K, Veselkov, D.A, Pan, X.-S, Sawhney, R, Thompson, A.W, McAuley, K.E, Fisher, L.M, Sanderson, M.R. 登録日 2008-12-30 公開日 2009-02-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases Nat.Struct.Mol.Biol., 16, 2009
3UOB	Crystal structure of Human Thymine DNA Glycosylase Bound to Substrate Analog 2'-deoxy-2'-beta-fluoro-cytidine 分子名称: 5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*GP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(1FC)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', G/T mismatch-specific thymine DNA glycosylase 著者 Zhang, L, He, C. 登録日 2011-11-16 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.011 Å) 主引用文献 Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat.Chem.Biol., 8, 2012
3E44	Q138F HincII bound to cleaved DNA (GTT | AAC) and Mn2+ 分子名称: 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DT)-3', 5'-D(P*DAP*DAP*DCP*DCP*DGP*DGP*DC)-3', MANGANESE (II) ION, ... 著者 Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. 登録日 2008-08-08 公開日 2008-08-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
4K9A	Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pG(2 ,5 )pA 分子名称: ADENOSINE MONOPHOSPHATE, Cyclic GMP-AMP synthase, DNA-F, ... 著者 Gao, P, Wu, Y, Patel, D.J. 登録日 2013-04-19 公開日 2013-05-15 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.264 Å) 主引用文献 Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
4K97	Structure of Ternary Complex of cGAS with dsDNA and Bound ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, DNA-F, ... 著者 Gao, P, Wu, Y, Patel, D.J. 登録日 2013-04-19 公開日 2013-05-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
4K99	Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppdG(2 ,5 )pdG 分子名称: 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, 3'-deoxy-guanosine 5'-monophosphate, Cyclic GMP-AMP synthase, ... 著者 Gao, P, Wu, Y, Patel, D.J. 登録日 2013-04-19 公開日 2013-05-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
4E9F	Structure of the glycosylase domain of MBD4 bound to AP site containing DNA 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*GP*CP*GP*(3DR)P*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*CP*GP*CP*GP*CP*TP*GP*G)-3'), ... 著者 Morera, S, Vigouroux, A. 登録日 2012-03-21 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Biochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNA. Nucleic Acids Res., 40, 2012
3U89	Crystal structure of one turn of g/c rich b-dna revisited 分子名称: 5'-D(*CP*CP*AP*GP*GP*CP*CP*TP*GP*G) -3', MAGNESIUM ION 著者 Maehigashi, T, Woods, K.K, Moulaei, T, Komeda, S, Williams, L.D. 登録日 2011-10-16 公開日 2011-11-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (0.96 Å) 主引用文献 B-DNA structure is intrinsically polymorphic: even at the level of base pair positions. Nucleic Acids Res., 40, 2012
4YIS	Crystal Structure of LAGLIDADG Meganuclease I-CpaMI Bound to Uncleaved DNA 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (28-MER), ... 著者 Hallinan, J.P, Kaiser, B.K, Stoddard, B.L. 登録日 2015-03-02 公開日 2016-03-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity. Structure, 24, 2016
316D	Selectivity of F8-actinomycin D for RNA:DNA hybrids and its anti-leukemia activity 分子名称: 8-FLUORO-ACTINOMYCIN D, DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3') 著者 Takusagawa, F, Takusagawa, K.T, Carlson, R.G, Weaver, R.F. 登録日 1997-03-05 公開日 1997-11-05 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Selectivity of F8-Actinomycin D for RNA:DNA Hybrids and its Anti-Leukemia Activity. Bioorg.Med.Chem., 5, 1997
6UKI	HhaI endonuclease in Complex with DNA in space group P212121 (pH 6.0) 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*CP*TP*GP*TP*TP*GP*CP*GP*CP*TP*TP*GP*GP*A)-3'), ... 著者 Horton, J.R, Cheng, X. 登録日 2019-10-04 公開日 2019-12-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom. Nucleic Acids Res., 48, 2020
6U81	Crystal Structure of the Double Homeodomain of DUX4 in Complex with a DNA aptamer 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*CP*CP*CP*AP*TP*TP*AP*CP*GP*C)-3'), ... 著者 Shi, K, Aihara, H. 登録日 2019-09-04 公開日 2020-02-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD. Faseb J., 34, 2020

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