8GCV
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![BU of 8gcv by Molmil](/molmil-images/mine/8gcv) | |
8GCT
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8GCS
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8GCL
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![BU of 8gcl by Molmil](/molmil-images/mine/8gcl) | Cryo-EM structure of hAQP2 in DDM | 分子名称: | Aquaporin-2 | 著者 | Kamegawa, A, Suzuki, S, Nishikawa, K, Numoto, N, Suzuki, H, Fujiyoshi, Y. | 登録日 | 2023-03-02 | 公開日 | 2023-06-21 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Structural analysis of the water channel AQP2 by single-particle cryo-EM. J.Struct.Biol., 215, 2023
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8GCI
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8GCC
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![BU of 8gcc by Molmil](/molmil-images/mine/8gcc) | T. cruzi topoisomerase II alpha bound to dsDNA and the covalent inhibitor CT1 | 分子名称: | 2-{3-[(Z)-iminomethyl]-1H-1,2,4-triazol-1-yl}-1-{(3M)-3-[2-(trifluoromethyl)phenyl]-6H-pyrrolo[3,4-b]pyridin-6-yl}ethan-1-one, DNA (28-MER), DNA topoisomerase 2 | 著者 | Schenk, A, Deniston, C, Noeske, J. | 登録日 | 2023-03-01 | 公開日 | 2023-07-12 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science, 380, 2023
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8GC9
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![BU of 8gc9 by Molmil](/molmil-images/mine/8gc9) | RNase A-Uridine 5'-Heptaphosphate (RNase A.p7U) | 分子名称: | Ribonuclease pancreatic, uridine 5'-heptaphosphate | 著者 | Park, G, Cummins, C. | 登録日 | 2023-03-01 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Experimental and Computational Studies for the Effect of Lengthening the Phosphate Chain of Nucleotide on the RNase A Inhibitors. To Be Published
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8GC8
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8GC1
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8GC0
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![BU of 8gc0 by Molmil](/molmil-images/mine/8gc0) | Crystal structure of PC39-50L, an anti-HIV broadly neutralizing antibody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PC39-50L Fab heavy chain, PC39-50L Fab light chain | 著者 | Murrell, S, Omorodion, O, Wilson, I.A. | 登録日 | 2023-02-28 | 公開日 | 2023-06-07 | 最終更新日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
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8GBZ
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![BU of 8gbz by Molmil](/molmil-images/mine/8gbz) | Crystal structure of PC39-55C, an anti-HIV broadly neutralizing antibody | 分子名称: | DI(HYDROXYETHYL)ETHER, PC39-55C Fab heavy chain, PC39-55C Fab light chain | 著者 | Murrell, S, Omorodion, O, Wilson, I.A. | 登録日 | 2023-02-28 | 公開日 | 2023-06-07 | 最終更新日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
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8GBY
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![BU of 8gby by Molmil](/molmil-images/mine/8gby) | Crystal structure of PC39-50E, an anti-HIV broadly neutralizing antibody | 分子名称: | GLYCEROL, PC39-50E Fab heavy chain, PC39-50E Fab light chain | 著者 | Murrell, S, Omorodion, O, Wilson, I.A. | 登録日 | 2023-02-28 | 公開日 | 2023-06-07 | 最終更新日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
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8GBX
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8GBW
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![BU of 8gbw by Molmil](/molmil-images/mine/8gbw) | Crystal structure of PC39-23D, an anti-HIV broadly neutralizing antibody | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PC39-23D Fab heavy chain, ... | 著者 | Murrell, S, Omorodion, O, Wilson, I.A. | 登録日 | 2023-02-28 | 公開日 | 2023-06-07 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
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8GBV
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![BU of 8gbv by Molmil](/molmil-images/mine/8gbv) | Crystal structure of PC39-17A, an anti-HIV broadly neutralizing antibody | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, PC39-17A Fab heavy chain, ... | 著者 | Murrell, S, Omorodion, O, Wilson, I.A. | 登録日 | 2023-02-28 | 公開日 | 2023-06-07 | 最終更新日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
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8GBU
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![BU of 8gbu by Molmil](/molmil-images/mine/8gbu) | Hepatitis B capsid Y132A mutant with compound AB-506 | 分子名称: | (1-methyl-1H-1,2,4-triazol-3-yl)methyl {(1S)-4-[(3-chloro-4-fluorophenyl)carbamoyl]-7-fluoro-2,3-dihydro-1H-inden-1-yl}carbamate, 1,2-ETHANEDIOL, Capsid protein | 著者 | Horanyi, P.S, Mayclin, S.J. | 登録日 | 2023-02-28 | 公開日 | 2023-09-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Design, synthesis, and structure-activity relationship of a bicyclic HBV capsid assembly modulator chemotype leading to the identification of clinical candidate AB-506. Bioorg.Med.Chem.Lett., 94, 2023
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8GBS
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![BU of 8gbs by Molmil](/molmil-images/mine/8gbs) | Integrative model of the native Ana GV shell | 分子名称: | Gas vesicle protein C, Gas vesicle structural protein | 著者 | Dutka, P, Metskas, L.A, Hurt, R.C, Salahshoor, H, Wang, T.U, Malounda, D, Lu, G, Chou, T.F, Shapiro, M.G, Jensen, J.J. | 登録日 | 2023-02-28 | 公開日 | 2023-04-19 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (8 Å) | 主引用文献 | Structure of Anabaena flos-aquae gas vesicles revealed by cryo-ET. Structure, 31, 2023
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8GBQ
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![BU of 8gbq by Molmil](/molmil-images/mine/8gbq) | Structure of RNF125 in complex with UbcH5b | 分子名称: | E3 ubiquitin-protein ligase RNF125, GLYCEROL, Ubiquitin-conjugating enzyme E2 D2, ... | 著者 | Middleton, A.J, Day, C.L, Fokkens, T.J. | 登録日 | 2023-02-27 | 公開日 | 2023-07-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation. Structure, 31, 2023
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8GBN
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![BU of 8gbn by Molmil](/molmil-images/mine/8gbn) | Structure of Apo Human SIRT5 P114T Mutant | 分子名称: | 1,2-ETHANEDIOL, NAD-dependent protein deacylase sirtuin-5, mitochondrial, ... | 著者 | Petrunak, E.M, Stuckey, J.A. | 登録日 | 2023-02-26 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice. Iscience, 27, 2024
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8GBL
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![BU of 8gbl by Molmil](/molmil-images/mine/8gbl) | Structure of Apo Human SIRT5 | 分子名称: | NAD-dependent protein deacylase sirtuin-5, mitochondrial, ZINC ION | 著者 | Petrunak, E.M, Stuckey, J.A. | 登録日 | 2023-02-26 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice. Iscience, 27, 2024
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8GB8
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8GB7
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8GB6
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8GB5
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![BU of 8gb5 by Molmil](/molmil-images/mine/8gb5) | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody 25F9 | 分子名称: | 25F9 Heavy chain, 25F9 Light chain, BICINE, ... | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | 登録日 | 2023-02-24 | 公開日 | 2023-05-24 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine. Sci Transl Med, 15, 2023
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8GAV
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![BU of 8gav by Molmil](/molmil-images/mine/8gav) | Structure of human NDS.3 Fab in complex with influenza virus neuraminidase from A/Darwin/09/2021 (H3N2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab NDS.3, heavy chain, ... | 著者 | Tsybovsky, Y, Lederhofer, J, Kwong, P.D, Kanekiyo, M. | 登録日 | 2023-02-23 | 公開日 | 2024-02-28 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Protective human monoclonal antibodies target conserved sites of vulnerability on the underside of influenza virus neuraminidase. Immunity, 57, 2024
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