5JNH
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7C35
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7WGI
| Crystal structure of AflSQS from Aspergillus flavus | 分子名称: | INDOLE, PHOSPHATE ION, Squalene synthase | 著者 | Shang, N, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2021-12-28 | 公開日 | 2022-11-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A Structural and Bioinformatics Investigation of a Fungal Squalene Synthase and Comparisons with Other Membrane Proteins. Acs Omega, 7, 2022
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6OS6
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5OCJ
| Crystal structure of Ag85C bound to cyclophostin 8beta inhibitor | 分子名称: | DIMETHYL SULFOXIDE, Diacylglycerol acyltransferase/mycolyltransferase Ag85C, methoxy-[(3~{R})-3-[(2~{R})-1-methoxy-1,3-bis(oxidanylidene)butan-2-yl]pentadecyl]phosphinic acid | 著者 | Viljoen, A, Richard, M, Nguyen, P.C, Spilling, C.D, Canaan, S, Cavalier, J.F, Blaise, M, Kremer, L. | 登録日 | 2017-07-03 | 公開日 | 2018-01-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Cyclipostins and cyclophostin analogs inhibit the antigen 85C from J. Biol. Chem., 293, 2018
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7WGH
| Crystal structure of AflSQS from Aspergillus flavus in complex with FSPP | 分子名称: | PHOSPHATE ION, PYROPHOSPHATE 2-, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ... | 著者 | Shang, N, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2021-12-28 | 公開日 | 2022-11-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | A Structural and Bioinformatics Investigation of a Fungal Squalene Synthase and Comparisons with Other Membrane Proteins. Acs Omega, 7, 2022
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5IX3
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5TDT
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5FAL
| Crystal structure of PvHCT in complex with CoA and p-coumaroyl-shikimate | 分子名称: | (3~{R},4~{R},5~{R})-5-[(~{E})-3-(4-hydroxyphenyl)prop-2-enoyl]oxy-3,4-bis(oxidanyl)cyclohexene-1-carboxylic acid, COENZYME A, GLYCEROL, ... | 著者 | Pereira, J.H, Moriarty, N.W, Eudes, A, Yogiswara, S, Wang, G, Benites, V.T, Baidoo, E.E.K, Lee, T.S, Keasling, J.D, Loque, D, Adams, P.D. | 登録日 | 2015-12-11 | 公開日 | 2016-02-24 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.861 Å) | 主引用文献 | Exploiting the Substrate Promiscuity of Hydroxycinnamoyl-CoA:Shikimate Hydroxycinnamoyl Transferase to Reduce Lignin. Plant Cell.Physiol., 57, 2016
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7CPY
| Lovastatin nonaketide synthase with LovC | 分子名称: | Lovastatin nonaketide synthase, enoyl reductase component lovC, polyketide synthase component, ... | 著者 | Wang, J, Wang, Z. | 登録日 | 2020-08-08 | 公開日 | 2021-01-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis for the biosynthesis of lovastatin. Nat Commun, 12, 2021
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6OR8
| An Unexpected Intermediate in the Reaction Catalyzed by Quinolinate Synthase | 分子名称: | 2-hydroxy-N-[(1S)-1-hydroxy-3-oxopropyl]-L-aspartic acid, IRON/SULFUR CLUSTER, PHOSPHATE ION, ... | 著者 | Esakova, O.A, Grove, T.L, Yennawar, N.H, Booker, S.J. | 登録日 | 2019-04-29 | 公開日 | 2019-10-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | An Unexpected Species Determined by X-ray Crystallography that May Represent an Intermediate in the Reaction Catalyzed by Quinolinate Synthase. J.Am.Chem.Soc., 141, 2019
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5FBT
| Crystal structure of rifampin phosphotransferase RPH-Lm from Listeria monocytogenes in complex with rifampin | 分子名称: | CHLORIDE ION, Phosphoenolpyruvate synthase, Rifampin | 著者 | Stogios, P.J, Wawrzak, Z, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2015-12-14 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | 主引用文献 | Rifampin phosphotransferase is an unusual antibiotic resistance kinase. Nat Commun, 7, 2016
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7CBF
| Crystal structure of benzophenone synthase from Garcinia mangostana L. pericarps reveals basis for substrate specificity and catalysis | 分子名称: | 2,4,6-trihydroxybenzophenone synthase, GLYCEROL, IMIDAZOLE, ... | 著者 | Songsiriritthigul, C, Nualkaew, N, Chen, C.-J. | 登録日 | 2020-06-12 | 公開日 | 2020-12-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Crystal structure of benzophenone synthase from Garcinia mangostana L. pericarps reveals basis for substrate specificity and catalysis. Acta Crystallogr.,Sect.F, 76, 2020
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3INV
| Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase COMPLEXED WITH NADPH, dUMP AND C-448 ANTIFOLATE | 分子名称: | 1-[3-(2,3-dichlorophenoxy)propoxy]-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | 著者 | Chitnumsub, P, Yuvaniyama, J, Yuthavong, Y. | 登録日 | 2009-08-13 | 公開日 | 2010-07-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Structural basis of antifolate inhibition of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase To be Published
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6ARL
| Aspergillus fumigatus Cytosolic Thiolase: Apo enzyme in complex with rubidium ions | 分子名称: | Acetyl-CoA acetyltransferase, CHLORIDE ION, GLYCEROL, ... | 著者 | Marshall, A.C, Bond, C.S, Bruning, J.B. | 登録日 | 2017-08-22 | 公開日 | 2018-05-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations Acs Catalysis, 8(3), 2018
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5TDV
| Intermediate O2 diiron complex in the Q228A variant of Toluene 4-moonoxygenase (T4moHD) | 分子名称: | FE (III) ION, PEROXIDE ION, Toluene-4-monooxygenase system protein A, ... | 著者 | Bailey, L.J, Acheson, J.F, Fox, B.G. | 登録日 | 2016-09-19 | 公開日 | 2017-03-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | In-crystal reaction cycle of a toluene-bound diiron hydroxylase. Nature, 544, 2017
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2VU1
| Biosynthetic thiolase from Z. ramigera. Complex of with O-pantheteine- 11-pivalate. | 分子名称: | ACETYL-COA ACETYLTRANSFERASE, PANTOTHENYL-AMINOETHANOL-11-PIVALIC ACID, SODIUM ION, ... | 著者 | Kursula, P, Schmitz, W, Wierenga, R.K. | 登録日 | 2008-05-19 | 公開日 | 2008-10-28 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | The Sulfur Atoms of the Substrate Coa and the Catalytic Cysteine are Required for a Productive Mode of Substrate Binding in Bacterial Biosynthetic Thiolase, a Thioester-Dependent Enzyme. FEBS J., 275, 2008
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7XIH
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7XIG
| Crystal structure of the aminopropyltransferase, SpeE from hyperthermophilic crenarchaeon, Pyrobaculum calidifontis in complex with 5'-methylthioadenosine (MTA) and spermine | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-DEOXY-5'-METHYLTHIOADENOSINE, Polyamine aminopropyltransferase, ... | 著者 | Mizohata, E, Yasuda, Y. | 登録日 | 2022-04-13 | 公開日 | 2022-06-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Substrate Specificity of an Aminopropyltransferase and the Biosynthesis Pathway of Polyamines in the Hyperthermophilic Crenarchaeon Pyrobaculum calidifontis. Catalysts, 12, 2022
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2WGE
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7XIF
| Crystal structure of the aminopropyltransferase, SpeE from hyperthermophilic crenarchaeon, Pyrobaculum calidifontis in complex with 5'-methylthioadenosine (MTA) alone or together with spermidine or thermospermine | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, N-(3-AMINO-PROPYL)-N-(5-AMINOPROPYL)-1,4-DIAMINOBUTANE, Polyamine aminopropyltransferase, ... | 著者 | Mizohata, E, Yasuda, Y. | 登録日 | 2022-04-13 | 公開日 | 2022-06-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Substrate Specificity of an Aminopropyltransferase and the Biosynthesis Pathway of Polyamines in the Hyperthermophilic Crenarchaeon Pyrobaculum calidifontis. Catalysts, 12, 2022
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2VU0
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4C2J
| Crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase in complex with CoA | 分子名称: | 1,2-ETHANEDIOL, 3-KETOACYL-COA THIOLASE, MITOCHONDRIAL, ... | 著者 | Kiema, T.-R, Harijan, R.K, Wierenga, R.K. | 登録日 | 2013-08-19 | 公開日 | 2014-09-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Crystal Structure of Human Mitochondrial 3-Ketoacyl-Coa Thiolase (T1): Insight Into the Reaction Mechanism of its Thiolase and Thioesterase Activities Acta Crystallogr.,Sect.D, 70, 2014
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6OK1
| Ltp2-ChsH2(DUF35) aldolase | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ChsH2(DUF35), ... | 著者 | Kimber, M.S, Mallette, E, Aggett, R, Seah, S.Y.K. | 登録日 | 2019-04-12 | 公開日 | 2019-06-26 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The steroid side-chain-cleaving aldolase Ltp2-ChsH2DUF35is a thiolase superfamily member with a radically repurposed active site. J.Biol.Chem., 294, 2019
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3KGB
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