PDB: 2849 件ウェブページステータス検索Chemie searchBIRD

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5VA3	Cryo-EM structure of the human ether-a-go-go related K+ channel 分子名称: Potassium voltage-gated channel subfamily H member 2 著者 Wang, W.W, MacKinnon, R. 登録日 2017-03-24 公開日 2017-05-03 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Cryo-EM Structure of the Open Human Ether-a-go-go-Related K(+) Channel hERG. Cell, 169, 2017
5VA2	Cryo-EM structure of the human ether-a-go-go related K+ channel 分子名称: Potassium voltage-gated channel subfamily H member 2 著者 Wang, W.W, MacKinnon, R. 登録日 2017-03-24 公開日 2017-05-03 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM Structure of the Open Human Ether-a-go-go-Related K(+) Channel hERG. Cell, 169, 2017
2LE7	Solution nmr structure of the S4S5 linker of herg potassium channel 分子名称: Potassium voltage-gated channel subfamily H member 2 著者 Ng, C.A, Kuchel, P.W, Vandenberg, J.I. 登録日 2011-06-13 公開日 2012-04-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating Plos One, 7, 2012
3PJZ	Crystal Structure of the Potassium Transporter TrkH from Vibrio parahaemolyticus 分子名称: POTASSIUM ION, Potassium uptake protein TrkH 著者 Cao, Y, Jin, X, Huang, H, Levin, E.J, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) 登録日 2010-11-10 公開日 2011-01-19 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (3.506 Å) 主引用文献 Crystal structure of a potassium ion transporter, TrkH. Nature, 471, 2011
2L0W	Solution NMR structure of the N-terminal PAS domain of HERG potassium channel 分子名称: Potassium voltage-gated channel, subfamily H (Eag-related), member 2, ... 著者 Ng, C.A, Hunter, M.J, Mobli, M, King, G.F, Kuchel, P.W, Vandenberg, J.I. 登録日 2010-07-19 公開日 2011-01-26 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The N-Terminal Tail of hERG Contains an Amphipathic alpha-Helix That Regulates Channel Deactivation PLoS ONE, 6, 2011
1S6X	Solution structure of VSTx 分子名称: KvAP CHANNEL 著者 Jung, H.J, Eu, Y.J, Kim, J.I. 登録日 2004-01-28 公開日 2005-03-22 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Solution structure and lipid membrane partitioning of VSTx1, an inhibitor of the KvAP potassium channel. Biochemistry, 44, 2005
4V0C	Crystal Structure of the Kv7.1 proximal C-terminal Domain in Complex with Calmodulin 分子名称: CALCIUM ION, CALMODULIN, POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 1, ... 著者 Sachyani, D, Hirsch, J.A. 登録日 2014-09-14 公開日 2014-11-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Structural Basis of a Kv7.1 Potassium Channel Gating Module: Studies of the Intracellular C-Terminal Domain in Complex with Calmodulin. Structure, 22, 2014
5V02	A positive allosteric modulator binding pocket in SK2 ion channels is shared by Riluzole and CyPPA 分子名称: 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine, CALCIUM ION, Calmodulin-1, ... 著者 Liu, S. 登録日 2017-02-28 公開日 2018-03-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 An Intracellular Allosteric Modulator Binding Pocket in SK2 Ion Channels Is Shared by Multiple Chemotypes. Structure, 26, 2018
6CPV	MicroED structure of NaK ion channel reveals a process of Na+ partition into the selectivity filter 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Potassium channel protein, SODIUM ION 著者 Liu, S, Gonen, T. 登録日 2018-03-14 公開日 2018-09-12 最終更新日 2023-10-04 実験手法 ELECTRON CRYSTALLOGRAPHY (2.5 Å) 主引用文献 MicroED structure of the NaK ion channel reveals a Na+partition process into the selectivity filter. Commun Biol, 1, 2018
5KUK	Crystal Structure of Inward Rectifier Kir2.2 K62W Mutant 分子名称: ATP-sensitive inward rectifier potassium channel 12, DECYL-BETA-D-MALTOPYRANOSIDE, POTASSIUM ION 著者 Lee, S.-J, Ren, F, Heyman, S, Yuan, P, Nichols, C.G. 登録日 2016-07-13 公開日 2016-08-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids. J.Gen.Physiol., 148, 2016
8A7X	NaK C-DI F92A mutant soaked in Cs+ 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CESIUM ION, POTASSIUM ION, ... 著者 Minniberger, S, Plested, A.J.R. 登録日 2022-06-21 公開日 2023-02-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Asymmetry and Ion Selectivity Properties of Bacterial Channel NaK Mutants Derived from Ionotropic Glutamate Receptors. J.Mol.Biol., 435, 2023
3E8B	Crystal Structure of the the open NaK channel- Rb+ complex 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Potassium channel protein, RUBIDIUM ION 著者 Jiang, Y, Alam, A. 登録日 2008-08-19 公開日 2008-12-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural analysis of ion selectivity in the NaK channel Nat.Struct.Mol.Biol., 16, 2009
3E89	Crystal Structure of the the open NaK channel-low Na+ complex 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CESIUM ION, Potassium channel protein, ... 著者 Jiang, Y, Alam, A. 登録日 2008-08-19 公開日 2008-12-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural analysis of ion selectivity in the NaK channel Nat.Struct.Mol.Biol., 16, 2009
3E8G	Crystal Structure of the the open NaK channel-Na+/Ca2+ complex 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CESIUM ION, ... 著者 Jiang, Y, Alam, A. 登録日 2008-08-19 公開日 2008-12-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural analysis of ion selectivity in the NaK channel Nat.Struct.Mol.Biol., 16, 2009
5VRE	Crystal structure of a lysosomal potassium-selective channel TMEM175 homolog from Chamaesiphon Minutus 分子名称: Putative integral membrane protein 著者 Lee, C, Guo, J, Jiang, Y. 登録日 2017-05-10 公開日 2017-07-19 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.299 Å) 主引用文献 The lysosomal potassium channel TMEM175 adopts a novel tetrameric architecture. Nature, 547, 2017
4WFH	Human TRAAK K+ channel in a Tl+ bound nonconductive conformation 分子名称: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ... 著者 Brohawn, S.G, MacKinnon, R. 登録日 2014-09-15 公開日 2014-12-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel. Nature, 516, 2014
4WFG	Human TRAAK K+ channel in a Tl+ bound conductive conformation 分子名称: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ... 著者 Brohawn, S.G, MacKinnon, R. 登録日 2014-09-15 公開日 2014-12-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel. Nature, 516, 2014
7PQU	Ligand-bound human Kv3.1 cryo-EM structure (Lu AG00563) 分子名称: 1-(4-methylphenyl)sulfonyl-N-(1,3-oxazol-2-ylmethyl)pyrrole-3-carboxamide, POTASSIUM ION, Potassium voltage-gated channel subfamily C member 1 著者 Botte, M, Huber, S, Bucher, D, Klint, J.K, Rodriguez, D, Tagmose, L, Chami, M, Cheng, R, Hennig, M, Abdul Rhaman, W. 登録日 2021-09-20 公開日 2022-08-17 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.03 Å) 主引用文献 Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3.1 channel reveal a novel binding site for positive modulators. Pnas Nexus, 1, 2022
6XIS	Cryo-EM structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in apo form 分子名称: G protein-activated inward rectifier potassium channel 2 著者 Niu, Y, Tao, X, MacKinnon, R. 登録日 2020-06-21 公開日 2020-10-07 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-EM analysis of PIP 2 regulation in mammalian GIRK channels. Elife, 9, 2020
7VNQ	Structure of human KCNQ4-ML213 complex in nanodisc 分子名称: (1S,2S,4R)-N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid, Calmodulin-3, POTASSIUM ION, ... 著者 Xu, F, Zheng, Y. 登録日 2021-10-11 公開日 2021-12-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 Structural insights into the lipid and ligand regulation of a human neuronal KCNQ channel. Neuron, 110, 2022
7VNR	Structure of human KCNQ4-ML213 complex in digitonin 分子名称: (1S,2S,4R)-N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid, Calmodulin-3, POTASSIUM ION, ... 著者 Xu, F, Zheng, Y. 登録日 2021-10-11 公開日 2021-12-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural insights into the lipid and ligand regulation of a human neuronal KCNQ channel. Neuron, 110, 2022
7VNP	Structure of human KCNQ4-ML213 complex with PIP2 分子名称: (1S,2S,4R)-N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid, Calmodulin-3, POTASSIUM ION, ... 著者 Xu, F, Zheng, Y. 登録日 2021-10-11 公開日 2021-12-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.79 Å) 主引用文献 Structural insights into the lipid and ligand regulation of a human neuronal KCNQ channel. Neuron, 110, 2022
7OOR	NaK C-DI mutant with Na+ and K+ 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... 著者 Minniberger, S, Plested, A.J.R. 登録日 2021-05-28 公開日 2022-06-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Asymmetry and Ion Selectivity Properties of Bacterial Channel NaK Mutants Derived from Ionotropic Glutamate Receptors. J.Mol.Biol., 435, 2023
7OPH	NaK S-DI mutant with Na+ and K+ 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... 著者 Minniberger, S, Plested, A.J.R. 登録日 2021-05-31 公開日 2022-06-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Asymmetry and Ion Selectivity Properties of Bacterial Channel NaK Mutants Derived from Ionotropic Glutamate Receptors. J.Mol.Biol., 435, 2023
7OOU	NaK C-DI mutant with Li+ and K+ 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... 著者 Minniberger, S, Plested, A.J.R. 登録日 2021-05-28 公開日 2022-06-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Asymmetry and Ion Selectivity Properties of Bacterial Channel NaK Mutants Derived from Ionotropic Glutamate Receptors. J.Mol.Biol., 435, 2023

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