PDB: 1856 件ウェブページステータス検索Chemie searchBIRD

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7D1M	CRYSTAL STRUCTURE OF THE SARS-CoV-2 MAIN PROTEASE COMPLEXED WITH GC376 分子名称: (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, DIMETHYL SULFOXIDE 著者 Fu, L.F, Gilski, M, Shabalin, I, Gao, G.F, Qi, J.X. 登録日 2020-09-14 公開日 2020-10-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease. Nat Commun, 11, 2020
7ACS	The SARS-CoV-2 nucleocapsid phosphoprotein N-terminal domain in complex with 7mer dsRNA 分子名称: Nucleoprotein, RNA (5'-R(P*CP*AP*CP*UP*GP*AP*C)-3'), RNA (5'-R(P*GP*UP*CP*AP*GP*UP*G)-3') 著者 Veverka, V. 登録日 2020-09-11 公開日 2020-11-04 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein. Plos Pathog., 16, 2020
7A4N	Cryo-EM structure of a prefusion stabilized SARS-CoV-2 Spike (D614N, R682S, R685G, A892P, A942P and V987P)(S-closed trimer) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin 著者 Rutten, L, Renault, L.L.R, Juraszek, J, Langedijk, J.P.M. 登録日 2020-08-20 公開日 2020-11-04 最終更新日 2021-01-27 実験手法 ELECTRON MICROSCOPY (2.75 Å) 主引用文献 Stabilizing the closed SARS-CoV-2 spike trimer. Nat Commun, 12, 2021
7KEB	SARS-CoV-2 D614G 1RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub-classification) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Gobeil, S, Acharya, P. 登録日 2020-10-10 公開日 2020-11-04 最終更新日 2021-03-31 実験手法 ELECTRON MICROSCOPY (3.48 Å) 主引用文献 D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021
7AD1	Cryo-EM structure of a prefusion stabilized SARS-CoV-2 Spike (D614N, R682S, R685G, A892P, A942P and V987P)(One up trimer) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Envelope glycoprotein,Spike glycoprotein,Envelope glycoprotein,SARS-CoV-2 S protein 著者 Rutten, L, Renault, L.L.R, Juraszek, J, Langedijk, J.P.M. 登録日 2020-09-14 公開日 2020-11-04 最終更新日 2021-01-27 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 Stabilizing the closed SARS-CoV-2 spike trimer. Nat Commun, 12, 2021
7KDI	SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer fully cleaved by furin without the P986-P987 stabilizing mutations (S-RRAR-D614G) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Gobeil, S, Acharya, P. 登録日 2020-10-08 公開日 2020-11-04 最終更新日 2021-03-31 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021
7KE8	SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub-classification) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Gobeil, S, Acharya, P. 登録日 2020-10-10 公開日 2020-11-04 最終更新日 2022-02-02 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021
7KDL	SARS-CoV-2 D614G 1-RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Gobeil, S, Acharya, P. 登録日 2020-10-08 公開日 2020-11-04 最終更新日 2021-03-31 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021
7KE4	SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G Sub-class) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Gobeil, S, Acharya, P. 登録日 2020-10-10 公開日 2020-11-04 最終更新日 2021-03-31 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021
7KE9	SARS-CoV-2 D614G 1-RBD-up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub-classification) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Gobeil, S, Acharya, P. 登録日 2020-10-10 公開日 2020-11-04 最終更新日 2021-03-31 実験手法 ELECTRON MICROSCOPY (3.08 Å) 主引用文献 D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021
7KDH	SARS-CoV-2 RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Gobeil, S, Acharya, P. 登録日 2020-10-08 公開日 2020-11-04 最終更新日 2021-03-31 実験手法 ELECTRON MICROSCOPY (3.33 Å) 主引用文献 D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021
7KEA	SARS-CoV-2 D614G 1-RBD-up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub classification) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Gobeil, S, Acharya, P. 登録日 2020-10-10 公開日 2020-11-04 最終更新日 2021-03-31 実験手法 ELECTRON MICROSCOPY (3.33 Å) 主引用文献 D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021
7KDG	SARS-CoV-2 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Gobeil, S, Acharya, P. 登録日 2020-10-08 公開日 2020-11-04 最終更新日 2021-03-31 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021
7KE6	SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub-classification) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Gobeil, S, Acharya, P. 登録日 2020-10-10 公開日 2020-11-04 最終更新日 2021-03-31 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021
7KDJ	SARS-CoV-2 D614G 1-RBD-up Spike Protein Trimer fully cleaved by furin without the P986-P987 stabilizing mutations (S-RRAR-D614G) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Gobeil, S, Acharya, P. 登録日 2020-10-08 公開日 2020-11-04 最終更新日 2021-03-31 実験手法 ELECTRON MICROSCOPY (3.49 Å) 主引用文献 D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021
7KE7	SARS-CoV-2 D614G 3-RBD-down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G Sub-Classification) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Gobeil, S, Acharya, P. 登録日 2020-10-10 公開日 2020-11-04 最終更新日 2021-03-31 実験手法 ELECTRON MICROSCOPY (3.32 Å) 主引用文献 D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021
7KDK	SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Gobeil, S, Acharya, P. 登録日 2020-10-08 公開日 2020-11-04 最終更新日 2021-03-31 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021
7KEC	SARS-CoV-2 D614G 1-RBD-up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G Sub-Classification) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Gobeil, S, Acharya, P. 登録日 2020-10-10 公開日 2020-11-04 最終更新日 2021-03-31 実験手法 ELECTRON MICROSCOPY (3.84 Å) 主引用文献 D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021
7D6H	Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant 分子名称: PHOSPHATE ION, Papain-like protease, ZINC ION 著者 Liu, J, Wang, Y, Pan, L. 登録日 2020-09-30 公開日 2020-11-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2. Cell Chem Biol, 28, 2021
7CJF	Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ... 著者 Guo, Y, Li, X, Zhang, G, Fu, D, Schweizer, L, Zhang, H, Rao, Z. 登録日 2020-07-10 公開日 2020-11-11 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.108 Å) 主引用文献 A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes. Nat Commun, 12, 2021
7C33	Macro domain of SARS-CoV-2 in complex with ADP-ribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein 3 著者 Lin, M.H, Hsu, C.H. 登録日 2020-05-11 公開日 2020-11-11 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.83 Å) 主引用文献 Structural, Biophysical, and Biochemical Elucidation of the SARS-CoV-2 Nonstructural Protein 3 Macro Domain. Acs Infect Dis., 6, 2020
7KJ3	SARS-CoV-2 Spike Glycoprotein with two ACE2 Bound 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... 著者 Zhang, J, Xiao, T.S, Cai, Y.F, Chen, B. 登録日 2020-10-25 公開日 2020-11-11 最終更新日 2021-02-24 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent. Nat.Struct.Mol.Biol., 28, 2021
7KJ5	SARS-CoV-2 Spike Glycoprotein, prefusion with one RBD up conformation 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Zhang, J, Xiao, T.S, Cai, Y.F, Chen, B. 登録日 2020-10-25 公開日 2020-11-11 最終更新日 2021-02-24 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent. Nat.Struct.Mol.Biol., 28, 2021
7KJ2	SARS-CoV-2 Spike Glycoprotein with one ACE2 Bound 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... 著者 Zhang, J, Xiao, T.S, Cai, Y.F, Chen, B. 登録日 2020-10-25 公開日 2020-11-11 最終更新日 2021-02-24 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent. Nat.Struct.Mol.Biol., 28, 2021
7KJ4	SARS-CoV-2 Spike Glycoprotein with three ACE2 Bound 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... 著者 Zhang, J, Xiao, T.S, Cai, Y.F, Chen, B. 登録日 2020-10-25 公開日 2020-11-11 最終更新日 2021-02-24 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent. Nat.Struct.Mol.Biol., 28, 2021

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