7KG3
Crystal structure of CoV-2 Nsp3 Macrodomain
Summary for 7KG3
Entry DOI | 10.2210/pdb7kg3/pdb |
Related | 7KFP 7KG0 7KG1 7KG6 7KG7 7KG8 |
Descriptor | Non-structural protein 3, MALONATE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (6 entities in total) |
Functional Keywords | hydrolase, sars-cov-2, macrodomain |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
Total number of polymer chains | 1 |
Total formula weight | 18894.27 |
Authors | Arvai, A.,Brosey, C.A.,Link, T.,Jones, D.E.,Ahmed, Z.,Tainer, J.A. (deposition date: 2020-10-15, release date: 2020-10-28, Last modification date: 2023-10-18) |
Primary citation | Brosey, C.A.,Houl, J.H.,Katsonis, P.,Balapiti-Modarage, L.P.F.,Bommagani, S.,Arvai, A.,Moiani, D.,Bacolla, A.,Link, T.,Warden, L.S.,Lichtarge, O.,Jones, D.E.,Ahmed, Z.,Tainer, J.A. Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors. Prog.Biophys.Mol.Biol., 163:171-186, 2021 Cited by PubMed: 33636189DOI: 10.1016/j.pbiomolbio.2021.02.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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