SARS-CoV-2 D614G 1-RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G)

Summary for 7KDL

EMDB information22826 22821 22822 22823 22824 22825
DescriptorSpike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywordssars-cov-2 spike protein trimer, viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains3
Total molecular weight439961.36
Gobeil, S.,Acharya, P. (deposition date: 2020-10-08, release date: 2020-11-04)
Primary citation
Gobeil, S.,Janowska, K.,McDowell, S.,Mansouri, K.,Parks, R.,Manne, K.,Stalls, V.,Kopp, M.,Henderson, R.,Edwards, R.J.,Haynes, B.F.,Acharya, P.
D614G mutation alters SARS-CoV-2 spike conformational dynamics and protease cleavage susceptibility at the S1/S2 junction.
Biorxiv, 2020
PubMed: 33052347 (PDB entries with the same primary citation)
DOI: 10.1101/2020.10.11.335299
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers0 0.3% 0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
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PDB entries from 2020-11-25