PDB: 215264 件ウェブページステータス検索Chemie searchBIRD

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1MV0	NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC 分子名称: Myc box-dependent-interacting protein 1, Myc proto-oncogene protein 著者 Pineda-Lucena, A, Arrowsmith, C.H. 登録日 2002-09-24 公開日 2003-09-30 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants. J.Mol.Biol., 351, 2005
4W92	Crystal structure of Bacillus subtilis cyclic-di-AMP riboswitch ydaO 分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, 1,2-ETHANEDIOL, C-di-AMP ribsoswitch, ... 著者 Jones, C.P, Ferre-D'Amare, A.R. 登録日 2014-08-26 公開日 2014-10-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.209 Å) 主引用文献 Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA. Embo J., 33, 2014
5W4S	Solution structure of C2 domain from protein kinase C alpha in ternary complex with calcium and V5-pHM peptide 分子名称: CALCIUM ION, Protein kinase C alpha type, V5-pHM peptide 著者 Yang, Y, Igumenova, T.I. 登録日 2017-06-12 公開日 2018-04-25 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structural Basis of Protein Kinase C alpha Regulation by the C-Terminal Tail. Biophys. J., 114, 2018
8CK8	STRUCTURE OF HIF2A-ARNT HETERODIMER IN COMPLEX WITH (S)-1-Cyclohexyloxy-5,5-difluoro-3-methanesulfonyl-5,6-dihydro-4H-cyclopenta[c]thiophen-4-ol 分子名称: (4~{S})-1-cyclohexyloxy-5,5-bis(fluoranyl)-3-methylsulfonyl-4,6-dihydrocyclopenta[c]thiophen-4-ol, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 著者 Musil, D. 登録日 2023-02-14 公開日 2023-07-19 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 Discovery of Cycloalkyl[ c ]thiophenes as Novel Scaffolds for Hypoxia-Inducible Factor-2 alpha Inhibitors. J.Med.Chem., 66, 2023
8CK3	STRUCTURE OF HIF2A-ARNT HETERODIMER IN COMPLEX WITH (S)-1-(3,5-Difluoro-phenyl)-5,5-difluoro-3-methanesulfonyl-5,6-dihydro-4H-cyclopenta[c]thiophen-4-ol 分子名称: (4~{S})-1-[3,5-bis(fluoranyl)phenyl]-5,5-bis(fluoranyl)-3-methylsulfonyl-4,6-dihydrocyclopenta[c]thiophen-4-ol, Aryl hydrocarbon receptor nuclear translocator, DIMETHYL SULFOXIDE, ... 著者 Musil, D, Lehmannn, M, Diehl, L. 登録日 2023-02-14 公開日 2023-07-19 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.707 Å) 主引用文献 Discovery of Cycloalkyl[ c ]thiophenes as Novel Scaffolds for Hypoxia-Inducible Factor-2 alpha Inhibitors. J.Med.Chem., 66, 2023
4WQB	Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - bisulfite soak 分子名称: DI(HYDROXYETHYL)ETHER, HEME C, IODIDE ION, ... 著者 Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M. 登録日 2014-10-21 公開日 2015-02-18 最終更新日 2015-04-15 実験手法 X-RAY DIFFRACTION (1.5013 Å) 主引用文献 Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION. J.Biol.Chem., 290, 2015
4WQ7	Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - "as isolated" form 分子名称: HEME C, IODIDE ION, SULFATE ION, ... 著者 Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M. 登録日 2014-10-21 公開日 2015-02-18 最終更新日 2015-04-15 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION. J.Biol.Chem., 290, 2015
3CZ6	Crystal Structure of the Rap1 C-terminus 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA-binding protein RAP1 著者 Feeser, E.A, Wolberger, C. 登録日 2008-04-28 公開日 2008-05-20 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural and functional studies of the Rap1 C-terminus reveal novel separation-of-function mutants. J.Mol.Biol., 380, 2008
4WHY	Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 3/11, P21 crystal form 分子名称: Heavy chain of Fab fragment derived from neutralizing antibody 3/11, Light chain of Fab fragment derived from neutralizing antibody 3/11, epitope peptide 著者 Krey, T, Rey, F.A. 登録日 2014-09-24 公開日 2014-12-17 最終更新日 2015-02-04 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein e2 recognized by broadly neutralizing antibodies. J.Virol., 89, 2015
4ZO5	PDE10 complexed with 4-isopropoxy-2-(2-(3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)isoindoline-1,3-dione 分子名称: 2-{2-[3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]ethyl}-4-(propan-2-yloxy)-1H-isoindole-1,3(2H)-dione, 3-(1-hydroxy-2-methylpropan-2-yl)-5-phenyl-3,5-dihydro-1H-imidazo[4,5-c][1,8]naphthyridine-2,4-dione, MAGNESIUM ION, ... 著者 Yan, Y. 登録日 2015-05-06 公開日 2015-08-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of [(11)C]MK-8193 as a PET tracer to measure target engagement of phosphodiesterase 10A (PDE10A) inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
7YVD	The crystal structure of the progerin C-terminal peptide and the Ig-like domain of lamin A/C 分子名称: Lamin-A/C, SELENOCYSTEINE 著者 Ahn, J, Ha, N.C. 登録日 2022-08-19 公開日 2023-08-30 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The crystal structure of the progerin C-terminal peptide and the Ig-like domain of lamin A/C To Be Published
2GGM	Human centrin 2 xeroderma pigmentosum group C protein complex 分子名称: CALCIUM ION, Centrin-2, DNA-repair protein complementing XP-C cells 著者 Thompson, J.R. 登録日 2006-03-24 公開日 2006-04-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The structure of the human centrin 2-xeroderma pigmentosum group C protein complex. J.Biol.Chem., 281, 2006
2G15	Structural Characterization of autoinhibited c-Met kinase 分子名称: activated met oncogene 著者 Wang, W, Marimuthu, A, Tsai, J, Kumar, A, Krupka, H.I, Zhang, C, Powell, B, Suzuki, Y, Nguyen, H, Tabrizizad, M, Luu, C, West, B.L. 登録日 2006-02-13 公開日 2006-03-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural characterization of autoinhibited c-Met kinase produced by coexpression in bacteria with phosphatase. Proc.Natl.Acad.Sci.Usa, 103, 2006
2G01	Pyrazoloquinolones as Novel, Selective JNK1 inhibitors 分子名称: 6-CHLORO-9-HYDROXY-1,3-DIMETHYL-1,9-DIHYDRO-4H-PYRAZOLO[3,4-B]QUINOLIN-4-ONE, C-jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 8, ... 著者 Abad-Zapatero, C. 登録日 2006-02-10 公開日 2006-04-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Synthesis and SAR of 1,9-dihydro-9-hydroxypyrazolo[3,4-b]quinolin-4-ones as novel, selective c-Jun N-terminal kinase inhibitors. Bioorg.Med.Chem.Lett., 16, 2006
2G2L	Crystal Structure of the Second PDZ Domain of SAP97 in Complex with a GluR-A C-terminal Peptide 分子名称: 18-mer peptide from glutamate receptor, ionotropic, AMPA1, ... 著者 Von Ossowski, I, Oksanen, E, Von Ossowski, L, Cai, C, Sundberg, M, Goldman, A, Keinanen, K. 登録日 2006-02-16 公開日 2006-08-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structure of the second PDZ domain of SAP97 in complex with a GluR-A C-terminal peptide Febs J., 273, 2006
3LLU	Crystal structure of the nucleotide-binding domain of Ras-related GTP-binding protein C 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related GTP-binding protein C, ... 著者 Nedyalkova, L, Tempel, W, Tong, Y, Crombet, L, Zhong, N, Guan, X, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2010-01-29 公開日 2010-02-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of the nucleotide-binding domain of Ras-related GTP-binding protein C to be published
2TN4	FOUR CALCIUM TNC 分子名称: CALCIUM ION, TROPONIN C 著者 Love, M.L, Dominguez, R, Houdusse, A, Cohen, C. 登録日 1997-09-18 公開日 1998-04-08 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of four Ca2+-bound troponin C at 2.0 A resolution: further insights into the Ca2+-switch in the calmodulin superfamily. Structure, 5, 1997
6LEN	Structure of NS11 bound FEM1C 分子名称: Protein fem-1 homolog C,NS11 peptide 著者 Chen, x, Liao, S, Xu, C. 登録日 2019-11-25 公開日 2020-10-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.383 Å) 主引用文献 Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
6LF0	Structure of FEM1C 分子名称: Protein fem-1 homolog C, SULFATE ION 著者 Chen, X, Liao, S, Xu, C. 登録日 2019-11-27 公開日 2020-10-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
6LEY	Structure of Sil1G bound FEM1C 分子名称: Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1 著者 Chen, X, Liao, S, Xu, C. 登録日 2019-11-27 公開日 2020-10-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
2GIR	Hepatitis C virus RNA-dependent RNA polymerase NS5B with NNI-1 inhibitor 分子名称: 3-{ISOPROPYL[(TRANS-4-METHYLCYCLOHEXYL)CARBONYL]AMINO}-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA-directed RNA polymerase 著者 Harris, S.F. 登録日 2006-03-29 公開日 2007-04-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Selection and characterization of replicon variants dually resistant to thumb- and palm-binding nonnucleoside polymerase inhibitors of the hepatitis C virus. J.Virol., 80, 2006
2GIQ	Hepatitis C virus RNA-dependent RNA polymerase NS5B with NNI-2 inhibitor 分子名称: 1-(2-CYCLOPROPYLETHYL)-3-(1,1-DIOXIDO-2H-1,2,4-BENZOTHIADIAZIN-3-YL)-6-FLUORO-4-HYDROXYQUINOLIN-2(1H)-ONE, RNA-directed RNA polymerase 著者 Harris, S.F. 登録日 2006-03-29 公開日 2007-04-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Selection and characterization of replicon variants dually resistant to thumb- and palm-binding nonnucleoside polymerase inhibitors of the hepatitis C virus. J.Virol., 80, 2006
6M9K	Crystal structure of lambda exonuclease in complex with the Red beta C-terminal domain 分子名称: Exonuclease, Recombination protein bet, SULFATE ION 著者 Bell, C.E, Caldwell, B.J. 登録日 2018-08-23 公開日 2019-01-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the Red beta C-terminal domain in complex with lambda Exonuclease reveals an unexpected homology with lambda Orf and an interaction with Escherichia coli single stranded DNA binding protein. Nucleic Acids Res., 47, 2019
6LBN	Structure of SIL1-bound FEM1C 分子名称: Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1 著者 Chen, X, Liao, S, Xu, C. 登録日 2019-11-14 公開日 2020-10-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.899 Å) 主引用文献 Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
7SC2	CRYSTAL STRUCTURE OF THE N-DOMAIN OF CARDIAC MUSCLE TROPONIN C TETHERED TO THE SWITCH REGION OF CARDIAC MUSCLE TROPONIN I (TETRAGONAL FORM) 分子名称: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles,Troponin I, ... 著者 Sack, J.S. 登録日 2021-09-27 公開日 2021-12-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.814 Å) 主引用文献 X-ray structure of a human cardiac muscle troponin C/troponin I chimera in two crystal forms. Acta Crystallogr.,Sect.F, 78, 2022

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